It is an important link for optimizing land and resource management and coordinating the relationship between people and land to analyze the spatio-temporal expansion characteristics and driving forces of impervious surface. But the research on the difference of impervious surface expansion and its influence mechanism in Yunnan needs to be improved. Therefore, data from 2006 to 2015 Statistical Yearbook of Yunnan and Tsinghua Universitys GAIA (Global Artificial Impervious Area) data are used to analyze the spatio-temporal expansion characteristics of impervious surfaces in the whole province, then the driving factors affecting expansion of impervious surfaces in Yunnan by using geographic detector is analyzed. The results are as follows: (1) From the perspective of space, from 2006 to 2015, the impervious surfaces of 16 prefectures and cities in Yunnan experienced unprecedented expansion, but there were regional differences, uneven expansion and other problems, among which Kunming, Qujing, Honghe Prefecture and Yuxi had a strong expansion. (2) In the time series, the impervious surface of Yunnan shows a state of continuous accelerating expansion. (3) The main factors influencing the expansion of impervious surface in Yunnan from 2006 to 2015 are the secondary industry, the tertiary industry and highway mileage, and the interaction among different factors has enhanced the expansion of impervious surface. The results can provide reference for understanding the mechanism of impervious surface expansion and promote sustainable development and coordinated development in Yunnan. [ABSTRACT FROM AUTHOR]