Search

A recent study conducted in Karnataka, India, explores the role of the enzyme aromatase in polycystic ovary syndrome (PCOS). The researchers found that down-regulation of aromatase leads to elevated levels of testosterone, a key characteristic of PCOS. The study also highlights the influence of genetic polymorphisms, microRNAs, pathogenic metabolism, and environmental toxins on the regulation of aromatase and steroidogenesis. The findings suggest that aromatase is a crucial factor in the pathophysiology of PCOS and warrant further investigation. [Extracted from the article]