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Twenty-two compounds were isolated from the fruit of Albizia lebbeck including one unprecedented, rare amino acid-derived zwitterionic and one new flavone derivative. The isolation was performed on repeated column chromatography over silica gel and their structures were determined by 1D-, 2D-NMR and HR-ESI-MS spectra together with reported data in the literature. The chemophenetic significance is also discussed. Some isolated compounds were reported for the first time to be found in the species. Additionally, compound 2 showed antibacterial activity and compounds 1 and 2 revealed moderate cytotoxic activity against the Raw 264.7 cancer cell line with IC50 values of 37.19 µM and 29.36 µM, respectively. Furthermore, a proposed biosynthetic pathway of compound 1 is described. [ABSTRACT FROM AUTHOR]

The phytochemical investigation of the CH 2 Cl 2 /MeOH (1:1) crude extract from the stems of Angylocalyx oligophyllus (Baker) led to the isolation and characterization of 2 α ,3 α ,24-trihydroxyolean-12-en-28-oïc acid (1), 2 α ,3 α ,24-trihydroxyolean-11,13(18)-dien-28-oic acid (2) betulinic acid (3), ursolic acid (4), lupeol (5), lupenone (6), 8- O -methylretusin (7), 3-methoxydainzein (8), afromosin (9), β -sitosterol (10), β -sitosterol 3- O - β - D -glucopyranoside (11), and α - D -glucopyranosyl- O -(1 → 2)- β - D -fructofuranoside (12). The structures of compounds 1 – 12 were elucidated on the basis of 1D and 2D NMR, mass spectrometry and the spectroscopic data as well as comparison with the literature. All the isolated compounds (1 – 12) were reported for the first time from the genus Angylocalyx. Compounds 1 and 2 are reported from the Fabaceae family for the first time. The chemophenetic significance of these compounds is also discussed. The stems of Angylocalyx oligophyllus (Baker) Baker f. and isolated compounds. [Display omitted] • Isolation of twelve compounds from the stem of Angylocalyx oligophyllus Baker. (Fabaceae). • First report in these compounds from the genus Angylocalyx. • First report of two compounds from the Fabaceae family. [ABSTRACT FROM AUTHOR]