We consider an asymmetric left-invariant norm ∥ ⋅ ∥ K in the first Heisenberg group ℍ 1 induced by a convex body K ⊂ ℝ 2 containing the origin in its interior. Associated to ∥ ⋅ ∥ K there is a perimeter functional, that coincides with the classical sub-Riemannian perimeter in case K is the closed unit disk centered at the origin of ℝ 2 . Under the assumption that K has C 2 boundary with strictly positive geodesic curvature we compute the first variation formula of perimeter for sets with C 2 boundary. The localization of the variational formula in the non-singular part of the boundary, composed of the points where the tangent plane is not horizontal, allows us to define a mean curvature function H K out of the singular set. In the case of non-vanishing mean curvature, the condition that H K be constant implies that the non-singular portion of the boundary is foliated by horizontal liftings of translations of ∂ K dilated by a factor of 1 H K . Based on this we can define a sphere 핊 K with constant mean curvature 1 by considering the union of all horizontal liftings of ∂ K starting from (0 , 0 , 0) until they meet again in a point of the vertical axis. We give some geometric properties of this sphere and, moreover, we prove that, up to non-homogeneous dilations and left-translations, they are the only solutions of the sub-Finsler isoperimetric problem in a restricted class of sets. [ABSTRACT FROM AUTHOR]