Since the beginning of the 21st century, with the continuous growth and improvement of the comprehensive strength of our national economy and the continuous improvement of our modern industrial machinery and equipment, the level of safety technology, production level, and quality management level see continuous steady improvement, resulting in the rapid economic growth of chemical industries in China in recent years. In recent years, chemicals have been widely used and demand is increasing. However, the physical properties of some chemical substances are very unstable and vary according to process conditions, making it difficult to control. At the same time, safety issues have become a major "red warning" for industrial enterprises. Various safety incidents have attracted social attention, and the chemical industry has also learned from them, sounding the safety alarm for itself and reviewing its own shortcomings, and taking improvement measures. Therefore, it is obviously necessary to always emphasize the concept of "safety first, prevention first, and comprehensive management" to prevent enterprise safety accidents. It is necessary to regularly investigate and analyze the situation of safety accidents to summarize and continuously improve. This is the most important thing for enterprises to prevent the continuous occurrence of safety accidents in a good and effective way. Regularly analyzing, summarizing, and improving safety issues are the best way to prevent accidents. Deep learning mainly relies on letting computers or other electronic devices perform iterative learning on a large number of data samples according to the rules defined by the program. The computer after learning will have the analysis ability similar to humans, but its analysis ability is limited to the range of the sample data to be learned. Artificial intelligence technology realizes an operation system that simulates human thinking through the definition of algorithms and programs. The use of deep learning and artificial intelligence in industrial enterprise safety production supervision can realize enterprise safety production supervision, early warning, and intelligent operation. Without the security of the production chain, a business cannot develop. Based on the basic theory of safety supervision and early warning in the field of enterprise safety production and related knowledge of artificial intelligence, this paper studies the work safety in the supervision and early warning mechanism abides by the selection principle of the management system, safety production indicators and indicator system, and conducts work based on the production work data of industrial plants. Reasonable safety supervision and early warning mechanism provide technical assistance for effectively controlling safety accidents in production and management measures to improve enterprise safety. [ABSTRACT FROM AUTHOR]