9 results on '"Tao Lin"'
Search Results
2. Higher family and individual resilience and lower perceived stress alleviate psychological distress in female breast cancer survivors with fertility intention: a cross-sectional study
- Author
-
Tao, Lin, Zhong, Ting, Hu, Xiaoxia, Fu, Lan, and Li, Junying
- Published
- 2023
- Full Text
- View/download PDF
3. Factors influencing the burden on spousal caregivers of breast cancer survivors
- Author
-
Tao, Lin, Hu, Xiaoxia, Chen, Hongxiu, Xiao, Shuwen, and Zhang, Xiaoxia
- Published
- 2022
- Full Text
- View/download PDF
4. Psychological distress in adult women of reproductive age at different stages after breast cancer diagnosis: A qualitative study.
- Author
-
Tao, Lin, Wang, Qiuzhou, Zeng, Xiaohong, Fu, Lan, Li, Junying, and Chen, Hong
- Subjects
- *
BREAST tumor diagnosis , *CHILDBEARING age , *FERTILITY , *PSYCHOLOGICAL distress , *REPRODUCTIVE health , *ATTITUDES toward illness , *QUALITATIVE research , *INTERVIEWING , *PSYCHOLOGY of women , *AGE distribution , *JUDGMENT sampling , *MENTAL fatigue , *THEMATIC analysis , *NURSING research , *PHYSICAL fitness , *PHENOMENOLOGY , *HEALTH education , *SOCIAL support , *PATIENTS' attitudes , *INTIMACY (Psychology) - Abstract
Aim: To explore the actual experience of psychological distress of adult women of reproductive age at different stages after breast cancer diagnosis. Design: Qualitative. Methods: Eighty‐one patients with breast cancer‐related distress thermometer scores >4 were selected using a purposive sampling method. Patients were divided into newly diagnosed and 1‐, 3‐, 6‐, 9‐ and 12‐month groups according to time since diagnosis and then interviewed. A phenomenological approach was adopted to analyse interview content, and different themes were extracted. Results: Women exhibited different levels of psychological distress depending on the time since diagnosis, with newly diagnosed patients showing the highest distress. Within 1 year post‐diagnosis, different events caused patients distress. Themes extracted at new diagnosis and 1‐, 3‐, 6‐, 9‐ and 12 months post‐diagnosis included sadness and disbelief, loss of control, optimistic but concerned, physical and mental exhaustion, difficulties returning to society and limited sexual intimacy, respectively; all groups expressed reproductive concerns. Conclusion: Clinical nurses should focus on different psychologically distressing events to provide targeted interventions at distinct phases. For women of childbearing age, clinical nurses should pay particular attention to patients' marriage and reproductive concerns. Implications for the Profession and/or Patient Care: During the year after a breast cancer diagnosis, patients of childbearing age experience events that cause psychological distress that differ depending on time since diagnosis. Nurses should focus on core stressful events and perform specific nursing interventions. Impact: To provide holistic care, nurses should consider the psychological and emotional changes patients may undergo. For women of childbearing age, clinical nurses should pay particular attention to patients' marriage and fertility concerns, and be able to provide evidence‐based professional guidance on reproductive preservation techniques. Reporting Method: The study was reported using the consolidated criteria for reporting qualitative research guidelines. Patient or Public Contribution: Patients contributed to data collection through interviews. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
5. Activation of Piezo1 increases the sensitivity of breast cancer to hyperthermia therapy.
- Author
-
Shao-kang Wang, Xiao-ting Zhang, Xuan-yao Jiang, Bi-jiang Geng, Tao-lin Qing, Lei Li, Yun Chen, Jin-feng Li, Xiao-fang Zhang, Shuo-gui Xu, Jiang-bo Zhu, Yu-ping Zhu, Mei-tang Wang, and Ji-kuai Chen
- Abstract
Photothermal therapy (PTT) of nanomaterials is an emerging novel therapeutic strategy for breast cancer. However, there exists an urgent need for appropriate strategies to enhance the antitumor efficacy of PTT and minimize damage to surrounding normal tissues. Piezo1 might be a promising novel photothermal therapeutic target for breast cancer. This study aims to explore the potential role of Piezo1 activation in the hyperthermia therapy of breast cancer cells and investigate the underlying mechanisms. Results showed that the specific agonist of Piezo1 ion channel (Yoda1) aggravated the cell death of breast cancer cells triggered by heat stress in vitro. Reactive oxygen species (ROS) production was significantly increased following heat stress, and Yoda1 exacerbated the rise in ROS release. GSK2795039, an inhibitor of NADPH oxidase 2 (NOX2), reversed the Yoda1-mediated aggravation of cellular injury and ROS generation after heat stress. The in vivo experiments demonstrate the well photothermal conversion efficiency of TiCN under the 1,064 nm laser irradiation, and Yoda1 increases the sensitivity of breast tumors to PTT in the presence of TiCN. Our study reveals that Piezo1 activation might serve as a photothermal sensitizer for PTT, which may develop as a promising therapeutic strategy for breast cancer. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
6. The Application of Mixed Reality to Sentinel Lymph Node Biopsy in Breast Cancer.
- Author
-
Tao, Lin, Feng, Zhenchu, Qi, Yuan, Shao, Nan, Wang, Xi, Ma, Fei, Wang, Chao, Qiu, Zhaowen, Liang, Wenlong, and Chen, Xi
- Subjects
- *
SENTINEL lymph node biopsy , *BREAST biopsy , *MIXED reality , *SENTINEL lymph nodes , *BREAST cancer - Abstract
Objective: To explore the value of mixed reality (MR) in sentinel lymph node biopsy (SLNB) in patients with breast cancer. Methods: A total of 300 patients with breast cancer who underwent SLNB enrolled and were randomly divided into two groups. In group A, only dye (an injection of methylene blue) was used to detect sentinel lymph nodes, while in group B MR was used for positioning in addition to dye. (MR localization method: Before the surgery, we built a 1:1 3D reconstruction model based on the patient's CT or MRI original data, and after the patient was injected with dye, we completed MR localization by overlapping the pre-marked image with the model.) Results: During surgery, the detection time in group B was significantly shorter than in group A (3.62 ± 1.20 vs.7.87 ± 1.86; p < 0.001). At 1-month post-surgery follow-up, the incidence of pain in group B was lower than that in group A (2.70 vs. 8.28%, p = 0.036). The incidence of upper limb dysfunction was lower in group B than in group A (2.03 vs. 8.97%, p = 0.009). In terms of the incidence of pain, group B was better than group A (0.68 vs. 3.45%, p = 0.094). The satisfaction of the two groups was scored, and the results showed that group B was better than group A (4.04 ± 0.91 vs.3.32 ± 0.94, p < 0.001). Conclusion: The application of MR to SLNB in breast cancer can significantly reduce the detection time and the occurrence of complications and improve patient satisfaction. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
7. Effects of family beliefs and family strength on individual resilience and quality of life among young breast cancer survivors: A cross‐sectional study.
- Author
-
Tao, Lin, Hu, Xiaoxia, Fu, Lan, Zhang, Xiaoxia, and Chen, Hong
- Subjects
- *
FAMILIES & psychology , *CANCER patient psychology , *STRUCTURAL equation modeling , *HOSPITALS , *CLUSTER sampling , *CONFIDENCE intervals , *CROSS-sectional method , *HEALTH status indicators , *QUANTITATIVE research , *SURVEYS , *NURSING practice , *PEARSON correlation (Statistics) , *QUALITY of life , *DESCRIPTIVE statistics , *QUESTIONNAIRES , *FAMILY relations , *VALUES (Ethics) , *STATISTICAL sampling , *DATA analysis software , *MAXIMUM likelihood statistics , *PSYCHOLOGICAL resilience , *BREAST tumors - Abstract
Aims and objectives: This study examines the effects of family beliefs and family strength on individual resilience and quality of life among young breast cancer survivors and determines whether family strength mediates the effect of family beliefs on individual resilience and quality of life. Background: Family beliefs and family strength are meaningful protective factors that help individuals maintain physical and mental health. However, few studies have explored their impact on individual resilience and quality of life. Design: This study was conducted using a cross‐sectional survey with a three‐stage, stratified, convenience sampling approach following the STROBE guideline. Methods: From August 2020 to May 2021, participants completed the shortened Chinese version of the Connor–Davidson Resilience Scale, the Chinese version of the Family Beliefs Scale, the Family Strength Scale and the Functional Assessment of Cancer Therapy‐Breast scale. Structural equation modelling and multiple mediation effects test were used to explore the relationships among family beliefs, family strength, individual resilience and quality of life. Results: The final model accounted for 44.5% and 78.1% of the total variance of individual resilience and quality of life, respectively. Family beliefs had an indirect effect on both individual resilience and quality of life through family strength. Family strength had a direct effect on individual resilience and had both a direct and an indirect effect on quality of life. Family strength mediated the correlations of family beliefs with individual resilience and quality of life. Conclusion: Mobilising family resources to establish healthy family beliefs and exert positive family strength will help increase young breast cancer survivors' individual resilience and improve quality of life. Relevance to clinical practice: This study confirms the importance for clinical nursing practice to mobilise family resources and develop interventions centred on family beliefs and family strength. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
8. Relationships between Attachment Style, Emotional Self-Disclosure, and Quality of Life among Young Breast Cancer Survivors: A Cross-Sectional Study.
- Author
-
Tao, Lin, Lv, Jieying, Tan, Xueling, Hu, Xiaoxia, Fu, Lan, and Li, Junying
- Abstract
This investigation aims to explore relationships between adult attachment, emotional self-disclosure, and quality of life (QoL). The study sample completed the Chinese versions of the Experiences in Close Relationships Inventory, the Functional Assessment of Cancer Therapy-Breast Scale, and the Distress Disclosure Index between October 2021 and March 2022. The relationships between adult attachment, emotional self-disclosure, and QoL were investigated using a multiple mediation effects test and structural equation modeling. Attachment anxiety and avoidance were risk factors for young Chinese breast cancer survivors' emotional self-disclosure and QoL. Emotional self-disclosure mediates the association between attachment anxiety or avoidance and QoL. Assessing and easing attachment anxiety and avoidance may improve the emotional self-disclosure and QoL of young breast cancer survivors. This study confirms that adult attachment plays an important role in young breast cancer patients' adaptation to the disease and that high adult anxiety and avoidance levels can significantly reduce emotional self-disclosure and QoL in young breast cancer survivors. Identifying attachment patterns can help caregivers better understand patients' responses, adaptation, and treatment adherence to cancer, thereby helping caregivers develop targeted and personalized cancer care practice programs or psychotherapy interventions to improve patients' physical and mental health outcomes. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
9. Activation of Piezo1 increases the sensitivity of breast cancer to hyperthermia therapy
- Author
-
Wang Shao-kang, Zhang Xiao-ting, Jiang Xuan-yao, Geng Bi-jiang, Qing Tao-lin, Li Lei, Chen Yun, Li Jin-feng, Zhang Xiao-fang, Xu Shuo-gui, Zhu Jiang-bo, Zhu Yu-ping, Wang Mei-tang, and Chen Ji-kuai
- Subjects
photothermal therapy ,heat stress ,piezo1 ,breast cancer ,Medicine - Abstract
Photothermal therapy (PTT) of nanomaterials is an emerging novel therapeutic strategy for breast cancer. However, there exists an urgent need for appropriate strategies to enhance the antitumor efficacy of PTT and minimize damage to surrounding normal tissues. Piezo1 might be a promising novel photothermal therapeutic target for breast cancer. This study aims to explore the potential role of Piezo1 activation in the hyperthermia therapy of breast cancer cells and investigate the underlying mechanisms. Results showed that the specific agonist of Piezo1 ion channel (Yoda1) aggravated the cell death of breast cancer cells triggered by heat stress in vitro. Reactive oxygen species (ROS) production was significantly increased following heat stress, and Yoda1 exacerbated the rise in ROS release. GSK2795039, an inhibitor of NADPH oxidase 2 (NOX2), reversed the Yoda1-mediated aggravation of cellular injury and ROS generation after heat stress. The in vivo experiments demonstrate the well photothermal conversion efficiency of TiCN under the 1,064 nm laser irradiation, and Yoda1 increases the sensitivity of breast tumors to PTT in the presence of TiCN. Our study reveals that Piezo1 activation might serve as a photothermal sensitizer for PTT, which may develop as a promising therapeutic strategy for breast cancer.
- Published
- 2024
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.