4 results
Search Results
2. Comparison of Clot Activator Gel Biochemistry Tubes.
- Author
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Güler, Eray Metin, Özkan, Beyza Nur, Beyaztaş, Hakan, Daştan, Ali İmran, and Yekrek, Mehmet Murat
- Subjects
STATISTICAL power analysis ,CENTRIFUGATION ,T-test (Statistics) ,CREATININE ,BLOOD chemical analysis ,AUTOANALYZERS ,BLOOD collection ,POTASSIUM ,ASPARTATE aminotransferase ,PHARMACEUTICAL gels ,BIOCHEMISTRY ,DESCRIPTIVE statistics ,LACTATE dehydrogenase ,CALCIUM ,UREA ,SODIUM ,ALANINE aminotransferase ,COLLECTION & preservation of biological specimens ,COMPARATIVE studies ,DATA analysis software ,ALBUMINS ,TRIGLYCERIDES ,CONFIDENCE intervals - Abstract
Introduction: The clinical laboratory testing process has three phases, and one of the most common errors that adversely affect the accuracy of laboratory test results occurs in the pre-analytical phase. Different brands of blood collection tubes used in laboratories can adversely affect the accuracy of the parameters. This study aims to compare the clot activator gel biochemistry tubes for selected clinical parameters. Methods: Fifty healthy volunteers aged between 18-70 years were included who didn't have any chronic or inflammatory disease, any clinical or pathological disease, and didn't use any medication. The biochemical parameters such as serum albumin, creatinine (crea), urea, triglyceride (TG), calcium (Ca), sodium (Na), potassium (K), and chloride (Cl) levels; aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) activity were measured by an autoanalyzer. Student's t-test and Bland-Altman plot methods were used for statistical data analysis by SPSS software. Results: There was no statistical difference between the two different tube brands in terms of all evaluated clinical parameters that could affect the accuracy of the test results. Discussion and Conclusion: When the BD® brand tube is taken as a reference, it is thought that AYSET® tubes give the same or close values, and the clinical use of AYSET® brand tubes will not cause an error in laboratory tests. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
3. Investigation of the Acute Subacute Toxicity of KL21® Supplementary Food Product in Rats.
- Author
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Yasar, Mustafa, Sarac, Guliz, Gok, Ali, Sipahi, Nisa, and Agan, Aydan Fulden
- Subjects
BIOCHEMISTRY ,EXPERIMENTAL design ,IN vivo studies ,ANIMAL experimentation ,HEMATOLOGY ,PATHOLOGY ,ONE-way analysis of variance ,DIETARY supplements ,RATS ,TOXICITY testing ,RESEARCH funding ,BLOOD testing ,HISTOLOGY ,DATA analysis software - Abstract
Objective: KL
21 ®; It is a food supplement using remember regeneration therapy method (RTM). KL21 ®. Whereas products that containing combined medicinal plants are expected to be beneficial for health, on the other hand, their toxic properties are able to potentially increase due to the interactions of the active ingredients in the plants. With this study, it was aimed to investigate the toxic effect of KL21 ®. Material-Method: In the study conducted with control (n: 8), acute (n: 8), subacute (n: 8) and post-subacute (n: 8) groups; the daily dose of the product was tested by gavage in 8-week-old female Wistar rats. Biochemical parameters P, Ca, ALB, TG, TP, TC, Creatinine, Bilirubin, GGT, ALP, AST and ALT were analyzed. In hematological parameters; WBC, RBC, PLT, HCT, HGB were examined. Liver, lung, spleen, kidney and heart tissues were investigated histopathologicaly. Clinical observation was made throughout the entire process. Results: When the acute, subacute and post-subacute groups were compared to control, it was observed that there was no significant difference in biochemical, hematological, histopathological terms. No toxicity-related side effects were found in clinical observations. Conclusion: The potential toxic effect of daily use dose of KL21 ® containing the combined medicinal plant was investigated in vivo. According to the hemogram, biochemistry and pathology tests, it was determined that it does not show acute and subacute toxicity. [ABSTRACT FROM AUTHOR]- Published
- 2022
- Full Text
- View/download PDF
4. New Research on Sepsis from Mardin Artuklu University Summarized (Osajin from Maclura pomifera alleviates sepsis-induced liver injury in rats: biochemical, histopathological and immunohistochemical estimation).
- Subjects
SEPSIS ,LIVER injuries ,SUPEROXIDE dismutase ,HISTOPATHOLOGY ,RATS - Abstract
A recent study conducted by researchers at Mardin Artuklu University in Turkey examined the effects of a flavonoid called osajin (OSJ) on liver damage caused by sepsis. The study used male rats divided into different groups and found that sepsis led to increased lipid peroxidation and decreased levels of glutathione and superoxide dismutase in the liver tissues. However, the administration of OSJ resulted in a significant decrease in lipid peroxidation and an increase in glutathione levels and superoxide dismutase activity. Additionally, OSJ reduced the expression of interleukin-33 and caspase-3 and improved histopathological integrity. The study concluded that OSJ has a hepatoprotective effect against sepsis-induced liver injury. [Extracted from the article]
- Published
- 2023
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