1. Unraveling the Intricate Interplay: Iron and Zinc’s Regulatory Mechanisms on Calcium Bioavailability During Intestinal Absorption.
- Author
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Li, Yi, Cheng, Yongqiang, and Tang, Ning
- Subjects
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IRON in the body , *INTESTINAL absorption , *MALNUTRITION , *IRON , *CALCIUM - Abstract
Calcium, iron, and zinc are essential minerals crucial for human health, yet their deficiencies can lead to debilitating conditions like osteoporosis, anemia, and chronic diseases. While calcium is known to interfere with iron and zinc absorption, the reverse is also true – iron and zinc, as micronutrients, can modulate calcium bioavailability. Unraveling the intricate interplay of these minerals’ absorption mechanisms in the intestine is paramount for developing effective strategies to combat nutritional deficiencies. This review delves into the current understanding of calcium, iron, and zinc absorption dynamics in the gut, exploring the effects of iron or zinc intake on calcium solubility and absorption processes. Furthermore, it elucidates the underlying molecular mechanisms governing these interactions, summarized through inductive methods. By shedding light on iron and zinc’s regulatory mechanisms on calcium bioavailability during intestinal absorption, this comprehensive analysis provides valuable insights for formulating efficient strategies to optimize mineral intake and absorption. Ultimately, this knowledge paves the way for preventing nutritional deficiencies that pose significant public health challenges. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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