1. Is four years enough? An audit of post-hepatectomy surveillance for liver metastases.
- Author
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Reid, Jessica L., Ting, Ying Yang, Salih, Salma, Trochsler, Markus I., Mazzarolo, Deanna, Bonnici, Aliyah, and Maddern, Guy J.
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COLORECTAL liver metastasis - Abstract
Optimal timing and modality of surveillance post hepatectomy for colorectal cancer liver metastases (CLM) has not been established. Recommendations vary between countries and surgical units. Individual clinicians do not always adhere to guidelines. Using a prospectively collected database of consecutive hepatectomy patients at The Queen Elizabeth Hospital in Adelaide, Australia, CLM patients were reviewed for evidence of recurrent disease (20 February 1996–30 June 2018). Timing and modality of disease detection was analysed. Follow up was until 30 June 2020 or death. 244 patients underwent hepatectomy for CLM during the study period. 139 patients (57%) experienced recurrence post initial hepatectomy (mean time 13.2 months; range 0.6–84.7). For all hepatic recurrences (n = 172), majority of disease was detected in the first seven months post hepatectomy (55%) and by four years, 97.7% of recurrent disease was detected. 51 patients underwent curative repeat hepatectomy after recurrence was detected. Nearly all disease was detected via surveillance CT (160/172; 93%); 12 patients presented with clinical symptoms. Hepatectomy patients are likely to experience recurrent disease and clinicians must ensure a robust surveillance plan is in place. We recommend a triple-phase CT at 6, 12, 18, 24, 36 and 48 months. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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