1. Intravenous chlorpromazine for acute paediatric migraine.
- Author
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Löllgen, Ruth MC, Babl, Franz E, Mackay, Mark T, Hill, Ashley, and Palmer, Greta M
- Subjects
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DRUG efficacy , *LENGTH of stay in hospitals , *HOSPITAL emergency services , *CONFIDENCE intervals , *MIGRAINE , *ANALGESICS , *CHLORPROMAZINE , *RETROSPECTIVE studies , *ACQUISITION of data , *COMPARATIVE studies , *OXYCODONE , *MEDICAL records , *DESCRIPTIVE statistics , *INTRAVENOUS injections , *DATA analysis software , *EVALUATION , *CHILDREN , *ADOLESCENCE - Abstract
Objective: In paediatric migraine, ibuprofen, acetaminophen and triptans are safe, effective therapies but there is scant paediatric data informing second‐line emergency treatment. Methods: Retrospective cohort study of children diagnosed with migraine at a tertiary children's hospital ED. Results: There were 207 children with migraine over a 1 year period. 46% received simple oral analgesia. 25% intravenous chlorpromazine, of whom 45% received further analgesia. Conclusions: While intravenous chlorpromazine as second‐line agent was mostly safe, it had unclear efficacy given the requirement for further treatment and hospital admissions. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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