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Background: The 2022/23 influenza season in the United Kingdom saw the return of influenza to prepandemic levels following two seasons with low influenza activity. The early season was dominated by A(H3N2), with cocirculation of A(H1N1), reaching a peak late December 2022, while influenza B circulated at low levels during the latter part of the season. From September to March 2022/23, influenza vaccines were offered, free of charge, to all aged 2–13 (and 14–15 in Scotland and Wales), adults up to 49 years of age with clinical risk conditions and adults aged 50 and above across the mainland United Kingdom. Methods: End‐of‐season adjusted vaccine effectiveness (VE) estimates against sentinel primary‐care attendance for influenza‐like illness, where influenza infection was laboratory confirmed, were calculated using the test negative design, adjusting for potential confounders. Methods: Results In the mainland United Kingdom, end‐of‐season VE against all laboratory‐confirmed influenza for all those > 65 years of age, most of whom received adjuvanted quadrivalent vaccines, was 30% (95% CI: −6% to 54%). VE for those aged 18–64, who largely received cell‐based vaccines, was 47% (95% CI: 37%–56%). Overall VE for 2–17 year olds, predominantly receiving live attenuated vaccines, was 66% (95% CI: 53%–76%). Conclusion: The paper provides evidence of moderate influenza VE in 2022/23. [ABSTRACT FROM AUTHOR]

Brown macroalgae habitats provide a range of ecosystem services, offering coastal protection, supporting and increasing biodiversity, and more recently have been recognized for their potential role as blue carbon habitats. Consequently, accurate areal estimates of these habitats are vitally important. Satellite imagery is often utilized for areal estimates of vegetated habitats due to their ability to capture vast areas but are disadvantaged by their lower resolution. In contrast, imagery collected by unmanned aerial vehicles (UAV) provide high‐resolution datasets but are unable to cover the necessary spatial scale required for calculating areal estimates at regional, national or international scales. This study successfully and accurately corrects the outputs from low‐resolution Sentinel 2 imagery to the standard of high‐resolution UAV imagery by using a novel brown algae index and a simple regression model to provide accurate spatial estimates. This model was applied to rocky shores across Wales, UK to predict a spatial extent of 6.2 km2 for three fucoid macroalgae species; Ascophyllum nodosum, Fucus vesiculosus and F. serratus. The regression model was validated in two ways. First, the data used to create the regression model was split to train and test (50:50) the model, with a root mean square error of ~8%–14%. Secondly, spatial estimates of fucoids in independent aerial imagery were assessed using aerial photography interpretation and compared to that of the regression model (7% difference). The carbon standing stock of fucoids calculated from the spatial estimate (6.2 km2) was found to be significantly lower than that of other marine carbon stores, indicating that fucoids do not significantly contribute as a blue carbon habitat based on biomass alone. This study produces a robust and accurate remote sensing technique to estimate spatial extent of macroalgae at large spatial scales, with possible worldwide applicability. [ABSTRACT FROM AUTHOR]

Context: Too many people living with chronic kidney disease are opting for and starting on hospital‐based dialysis compared to a home‐based kidney replacement therapy. Dialysis services are becoming financially unsustainable. Objective: This study aimed to assess the efficacy of coproductive research in chronic kidney disease service improvement to achieve greater sustainability. Design: A 2‐year coproductive service improvement study was conducted with multiple stakeholders with the specific intention of maximizing engagement with the national health kidney services, patients and public. Setting and Participants: A national health kidney service (3 health boards, 18 dialysis units), patients and families (n = 50), multidisciplinary teams including doctors, nurses, psychologists, social workers, and so forth (n = 68), kidney charities, independent dialysis service providers and wider social services were part of this study. Findings: Coproductive research identified underutilized resources (e.g., patients on home dialysis and social services) and their potential, highlighted unmet social care needs for patients and families and informed service redesign. Education packages were reimagined to support the home dialysis agenda including opportunities for wider service input. The impacts of one size fits all approaches to dialysis on specialist workforce skills were made clearer and also professional, patient and public perceptions of key sustainability policies. Discussion and Conclusions: Patient and key stakeholders mapped out new ways to link services to create more sustainable models of kidney health and social care. Maintaining principles of knowledge coproduction could help achieve financial sustainability and move towards more prudent adult chronic kidney disease services. Patient or Public Contribution: Involved in developing research questions, study design, management and conduct, interpretation of evidence and dissemination. [ABSTRACT FROM AUTHOR]

The use of regulation of sex work is undergoing sweeping changes across Europe and client criminalization is becoming very widespread, with conflicting claims about the intended and actual consequences of this policy. We discuss changes in demand for paid sex accompanying the criminalization of prostitution in the United Kingdom, which moved from a relatively permissive regime under the Wolfenden Report of 1960, to a much harder line of aiming to crack down on prostitution with the Prostitution (Public Places) Scotland Act 2007 and the Policing and Crime Act of 2009 in England and Wales. We make use of two waves of the British National Survey of Sexual Attitudes and Lifestyles (NATSAL2, conducted in 2000–2001 and NATSAL3, conducted in 2010–2012) to document the changes in both the amount of demand for paid sex and in the type of clients that have taken place across the two waves, and their possible implications for policies that frame prostitution as a form of crime. [ABSTRACT FROM AUTHOR]