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Background: Evolution is a unifying theme in biology and its understanding is essential to address sustainability problems. However, many people across the world do not understand evolution. Textbooks are among the most widely used educational resources and the way they depict evolution may greatly impact students' scientific literacy in evolution. In this paper we investigate which evolution concepts are addressed in European science textbooks, from the 1st to the 9th grade. A content analysis using the 'Framework for the Assessment of school Curricula on the presence of Evolutionary concepts", was performed on textbooks from eight European countries: Belgium, Cyprus, Czech Republic, Greece, Italy, Netherlands, Portugal and Slovenia. At least two experienced coders per country independently analysed the texts, images and activities, discussed the results and reached a final consensus. Results: Our results show that textbooks lack or rarely address concepts considered important for evolution understanding, notably the processes driving evolution and their daily life implications, limiting opportunities for education for sustainability. Conclusions: We recommend that science textbooks emphasize evolution and its processes since the first school years. This recommendation is particularly relevant for the analysed textbooks from Cyprus and Belgium, that cover less than 45% of the concepts important to evolution literacy. [ABSTRACT FROM AUTHOR]

Social media platforms can play a pivotal role in shaping public opinion during times of crisis and controversy. The COVID-19 pandemic resulted in a large amount of dubious information being shared online. In Belgium, a crisis emerged during the pandemic when a soldier (Jürgen Conings) went missing with stolen weaponry after threatening politicians and virologists. This case created further division and polarization in online discussions. In this paper, we develop a methodology to study the potential of coordinated spread of incorrect information online. We combine network science and content analysis to infer and study the social network of users discussing the case, the news websites shared by those users, and their narratives. Additionally, we examined indications of bots or coordinated behavior among the users. Our findings reveal the presence of distinct communities within the discourse. Major news outlets, conspiracy theory websites, and anti-vax platforms were identified as the primary sources of (dis)information sharing. We also detected potential coordinated behavior and bot activity, indicating possible attempts to manipulate the discourse. We used the rapid semantic similarity network for the analysis of text, but our approach can be extended to the analysis of images, videos, and other types of content. These results provide insights into the role of social media in shaping public opinion during times of crisis and underscore the need for improved strategies to detect and mitigate disinformation campaigns and online discourse manipulation. Our research can aid intelligence community members in identifying and disrupting networks that spread extremist ideologies and false information, thereby promoting a more informed and resilient society. [ABSTRACT FROM AUTHOR]

In the geological disposal of high-level radioactive waste in argillaceous rocks, studying the barrier integrity after gas transport and the pathway closure thanks to self-sealing capacity is a crucial aspect for the safety assessment. This paper presents experimental research in Boom Clay (a potential host rock in Belgium) to evaluate the effectiveness of self-sealing and possible fissure reactivation during a second gas invasion event. Initial water permeability under oedometer conditions was first measured on samples at two bedding orientations, being higher the sample with bedding planes parallel to flow, highlighting marked anisotropy. Then, gas injection tests at a constant volume rate were performed. Results indicated that Boom Clay underwent expansion and degradation during gas injection due to the development of fissures that were quantified using microstructural techniques. The computed effective gas permeability was not significantly dependent on bedding orientation and was slightly larger than the initial intrinsic water permeability. The re-saturation of the samples led to a recovery of the initial water permeability for both orientations, replicating the original anisotropy. The microstructural analyses confirmed the gas pathways' closure, indicating good self-sealing and the regaining of the hydraulic barrier function. However, a small volume of large unconnected pores was detected on undrained unloading before the microstructural study. An additional gas injection after the self-sealing resulted in a higher effective gas permeability and a larger increase in pore volume, suggesting the reopening of fissures generated during the first injection. Finally, the experimental data were compiled within a multi-scale phenomenological model to relate the microstructural information to macroscopic flow transport properties capturing the intrinsic permeability increase on gas invasion and its recovery during self-sealing. Highlights: Gas transport on Boom Clay occurs along fissures, increasing its permeability The re-saturation process induces the recovery of the initial water permeability, demonstrating an excellent self-sealing capacity. A subsequent gas injection after the re-saturation suggests the reopening of previous gas paths. A multi-scale model is proposed to account for the permeability changes derived from a microstructural damage variable. [ABSTRACT FROM AUTHOR]

In a healthcare context, the success of a fire safety procedure in a real-life emergency mainly depends on staff decisions and actions. One of the factors influencing staff decision-making is their training. In most healthcare facilities, safety educators use slide-based lectures as a training tool. Virtual Reality (VR) is gaining fire safety community attention for being an interesting training tool. However, few studies have assessed the effectiveness of VR-based fire safety training simulators compared with a slide-based lecture. The present research proposes a novel non-immersive VR-based training for healthcare fire safety education. This paper describes the prototyping steps required to develop a non-immersive VR serious game (SG) to train the staff of Vincent Van Gogh (VVG) hospital in Belgium. The paper finally validates the VR SG comparing its effectiveness against slide-based lecture training. 78 staff from VVG hospital in Belgium participated in this study. They were divided into two groups: Group A was trained using a slide-based lecture, and Group B was trained using the VR SG. The results indicated that the VR SG was more effective than the slide-based lecture in terms of knowledge acquisition and retention and in terms of self-efficacy increment in short and long terms than the slide-based lecture. [ABSTRACT FROM AUTHOR]

The BELSAR dataset consists of high-resolution multitemporal airborne mono- and bistatic fully-polarimetric synthetic aperture radar (SAR) data in L-band, alongside concurrent measurements of vegetation and soil biogeophysical variables measured in maize and winter wheat fields during the summer of 2018 in Belgium. Its collection was funded by the European Space Agency (ESA) to address the lack of publicly-accessible experimental datasets combining multistatic SAR and in situ measurements. As such, it offers an opportunity to advance the development of SAR remote sensing science and applications for agricultural monitoring and hydrology. This paper aims to facilitate its adoption and exploration by offering comprehensive documentation and integrating its multiple data sources into a unified, analysis-ready dataset. [ABSTRACT FROM AUTHOR]

This paper started from an inductive ethnography conducted within a cancer research lab in Belgium. The primary objective was to explore how researchers make decisions and rationalize their scientific practices. Through data collected from participant observation, interviews, and analysis of research protocols, the study exposes serious knowledge gaps that compromise research ethics. Specifically, the findings reveal the scientists' need for more understanding of the validity of their lab machines and the readymade consumables procured from external providers. Moreover, without questioning this dependency, our participants (scientists) rely heavily on machines and consumables for almost all their research protocols. The findings suggest that cancer researchers place unjustifiable trust in the lab's machines and the external providers' reliability; this compromises the following three fundamental ethical principles: research integrity, responsible conduct, and the responsibility of using resources and technologies. [ABSTRACT FROM AUTHOR]

R&D activities by indigenous firms create new knowledge and technology in a region, while foreign-owned firms bring advanced knowledge and technologies from their home countries. This paper analyses the spillover effects of R&D-active or foreign-owned firms on total factor productivity of domestic non-R&D active firms. It combines two sets of literature: the one on spillover effects of intra-industry and inter-industry linkages and the other on the regional context in which these linkages occur. As measured through input-output tables, industry linkages reveal that R&D or FDI spillovers take on diverse roles in regions. Focusing on productivity spillover effects on domestic non-R&D active firms in three regions in Belgium between 2000 and 2017, we conclude that R&D spillovers generally occur more frequently than FDI spillovers. By focussing on two sources of spillovers, the paper offers a more nuanced picture of industrial transformation and regional path development. Region-specific analyses show that the effects on the productivity of domestic non-R&D active firms originate from different spillover sources. The impact of spillovers and their contribution to industrial transformation differs according to the regional development path characterised by the varying degrees of organisational thickness and specialisation of the regional innovation system. Linkages of R&D active or foreign-owned firms with domestic non-R&D active firms exert a heterogeneous impact on their productivity. Therefore, an adapted regional innovation policy, such as smart specialisation, should consider these region-specific spillover effects on productivity when establishing future regional development paths. [ABSTRACT FROM AUTHOR]

Background: At the COP21, cities were recognised as key actors in combatting climate change. In supporting cities, climate city networks such as transnational climate networks (TCNs) and national climate networks (NCNs) have emerged to enable cities in building capacities and formulating climate policy whilst also encouraging citizen engagement and participation in public decision-making. This paper addresses the question whether and how TCN or NCN membership enables municipalities to implement citizen participation in public decision-making. Six propositions are presented addressing: presumed influence of TCN membership on citizen participation, organization of citizen participation, initiator capacity, goal setting, involvement of stakeholders, participatory methods used, and planning processes. A multi-case study research design is used to verify these propositions, comprising of four medium-sized cities in the Netherlands and three in Belgium. Results: Results of the analysis of four cities in The Netherlands show that municipalities having membership to climate city networks only to a low extent empower citizen participation via local climate agendas. Citizen participation emerges rather bottom-up via local initiatives or capacity building via EU framework programs—outside TCNs or NCNs—that better suit financial needs and provide more immediate benefits to municipalities. None of the six propositions were confirmed. A more positive image resulted from the Belgian cases that moderately confirmed four out of six propositions (i.e., organizing citizen participation, goal setting, selection of methods, and planning), and featured indirect empowerment via externally funded implementation projects following firm integration of participation in local climate policy through TCN influence. Conclusions: In terms of citizen participation selected municipalities in the Netherlands having TCN and/or NCN membership only to a small extent differ from those not having membership. This is partly due to poor implementation of TCNs and NCNs—with Covenant of Mayors and 'Klimaatverbond' lacking support structure and capacity—having lost importance during the past years. However, there is reason to believe that context makes a difference as revealed by the cases from Belgium, which revealed more positive results. [ABSTRACT FROM AUTHOR]

Most studies on the spatial determinants of radical voting adopt a purely contemporary approach, suggesting that the current characteristics of one's geographical environment (most notably diversity and economic deprivation) largely determine the propensity to vote for a radical party. While this approach has led to new insights, in the current paper we also investigate whether there is a historical pattern with regard the spatial determinants of radical voting. Theoretically, this would suggest there is at least some form of continuity between the 'tribalist' voting of the 1930s (Popper, The open society and its enemies, Routledge, London, 1945), and the current wave of populist voting. In this results in the region. Our analysis, however, does not show any significant correlation between both results at the level of the small electoral districts. We do find more support for some level of historical continuity between communist electoral scores and left populist voting, than for the same relation on the radical right side of the electoral spectrum, and we close by offering some speculation on causes for this lack of continuity. [ABSTRACT FROM AUTHOR]

This correction notice addresses errors in the original article titled "In-Season Potato Crop Nitrogen Status Assessment from Satellite and Meteorological Data." The errors pertain to the grouping of tuber samples and the calculation of biomass per hectare. While these errors do not compromise the overall findings of the paper, they require minor corrections in the results and discussion sections. The corrected figures and details of the corrections are provided in the notice. The article discusses the assessment of potato crop nitrogen status using remote sensing and meteorological data, highlighting the relevance of assessing shoots biomass and nitrogen content. The study focuses on potato fields in Belgium and emphasizes the need for efficient monitoring and advisory systems for potato fertilization. [Extracted from the article]

In clinical practice, many drug therapies are associated with prolongation of the QT interval. In literature, estimation of the risk of prescribing drug-induced QT prolongation is mainly executed by means of logistic regression; only one paper reported the use of machine learning techniques. In this paper, we compare the performance of both techniques on the same dataset. High risk for QT prolongation was defined as having a corrected QT interval (QTc) ≥ 450 ms or ≥ 470 ms for respectively male and female patients. Both conventional statistical methods (CSM) and machine learning techniques (MLT) were used. All algorithms were validated internally and with a hold-out dataset of respectively 512 and 102 drug-drug interactions with possible drug-induced QTc prolongation. MLT outperformed the best CSM in both internal and hold-out validation. Random forest and Adaboost classification performed best in the hold-out set with an equal harmonic mean of sensitivity and specificity (HMSS) of 81.2% and an equal accuracy of 82.4% in a hold-out dataset. Sensitivity and specificity were both high (respectively 75.6% and 87.7%). The most important features were baseline QTc value, C-reactive protein level, heart rate at baseline, age, calcium level, renal function, serum potassium level and the atrial fibrillation status. All CSM performed similarly with HMSS varying between 60.3% and 66.3%. The overall performance of logistic regression was 62.0%. MLT (bagging and boosting) outperform CSM in predicting drug-induced QTc prolongation. Additionally, 19.2% was gained in terms of performance by random forest and Adaboost classification compared to logistic regression (the most used technique in literature in estimating the risk for QTc prolongation). Future research should focus on testing the classification on fully external data, further exploring potential of other (new) machine and deep learning models and on generating data pipelines to automatically feed the data to the classifier used. [ABSTRACT FROM AUTHOR]

Using time use diary data collected among 2603 teachers from the Flemish community of Belgium, this article investigates the 'family friendliness' of the teaching profession by exploring the family time of teachers in couple households with children. Teachers are an interesting case as the teaching profession is heavily feminised and considered to be a 'family friendly' occupation; it allows to synchronize the workers' schedule with their children's. Flexible work arrangements such as schedule or work-place flexibility function as so called 'boundary-spanning strategies'. However, research on the impact of flexible work on work-life balance has shown mixed results. This paper develops a number of time-use based indicators to measure the quality of family time and validates these by relating them to work-life balance. Subsequently, it is assessed how teachers' use of work time flexibility affects the quality of family time to evaluate whether this flexibility can be understood as a resource for increasing work-family balance. Results show that teachers with children have a better quality of family time and subsequently a better work-life balance if they work on standard hours rather than using their schedule flexibility to optimize the amount of family time. Highlights: Postponing work from afternoons to evenings and weekends proves to be detrimental for the quality of family time. The quality of family time is more important for self-reported work-life balance than the total amount of family time. Uncontaminated family leisure time is positively associated with the perceived work-life balance. Contaminated non-free time with family and fragmented shared time is negatively associated with the perceived work-life balance. [ABSTRACT FROM AUTHOR]

We examine the drivers of research performance of 1431 economists from six European countries. Data from the Scopus database are collected. We compare the relative performance of economists from three northern European countries: Belgium, Denmark and Germany with three from the south: Greece, Italy and Portugal. Relative performance is measured as the deviation from the country average in both citations and papers. The dependent variables take the value of 1 if the productivity of the researcher is above the country average and 0 if it is below. Probit/logit analysis is employed and marginal effects are estimated to examine the significance of factors like the country of their PhD studies, gender and inbreeding at the national level. A US PhD or a German PhD affects negatively the relative productivity of German economists. Inbreeding at the national level (locally trained economists) reduces productivity among Greek, Italian and Portuguese economists. Gender is significant in the case of Denmark, Germany and Italy, but it does not affect productivity in Belgium, Greece and Portugal. [ABSTRACT FROM AUTHOR]

In this paper, I investigated whether the sustainability attitudes and behaviour of young people are similar to those of the older generation. Furthermore, I examined to which extent today's parents play a role as socialization agents in shaping the broader sustainability attitudes and behaviour of their children by investigating whether specific family characteristics are important to explain this association. The research questions were analysed by using data from a Belgian study conducted among Flemish pupils from 47 primary and secondary schools and one of their parents (n = 880). I found that children's attitudes towards sustainability are higher compared to those of the older generation (e.g. their parents) but that the older generation, on the contrary, act more sustainably. Furthermore, there were small but positive correlations within the family for sustainability attitudes and behaviour. Finally, the results showed that increased intrafamily discussions are associated with more sustainable attitudinal parent–child congruence. However, the results did not provide evidence in support of behavioural congruence. It was concluded that the transmission of sustainability attitudes and behaviour is not limited to the classic top-down approach where parents influence children's attitudes and behaviour and children are considered as passive recipients. [ABSTRACT FROM AUTHOR]

In intensive European agricultural areas, the control of weeds and wildlife within plots is of great importance. Yet, we can observe in many farming systems a renewal of farmers' relationships with nature. Using the theoretical framework of care ethics, this paper aims to answer the following question: how observing plots allows farmers to develop more cooperation with nature in field crops? We base our results on an ethnographic survey conducted in Wallonia (Belgium) in 2019 among farm advisors and farmers in conventional, organic and conservation agriculture. The 19 in-depth interviews crossed partly with micro phenomenological interviews and participant observation sessions revealed that: (1) Observing plots increase farmers' attentiveness to plots and plants, and favor care and knowledge based on direct contact with nature ; (2) Such observations renew how farmers take care of their plots and plants, towards adaptation, limitation and reduction of pesticides; (3) They also allow farmers to cooperate with specific species. In conclusion, we underline the importance of direct knowledge on agrosystems based on attentiveness to enable farmers to diversify how they relate to non-humans and especially how they care for their plots and plants. The attentiveness developed through plot observations thus enables farmers to establish more complex relationships with nature, made up of ecological care, based in particular on cooperation with non-humans. This emphasizes the value of the ethic of care in order to build communities. Declaration of competing interest. [ABSTRACT FROM AUTHOR]

This manuscript explores the potential of macro-X-ray fluorescence (MA-XRF) for the non-invasive analysis of heritage textiles. XRF, especially with the portable instruments, is a well-known technique for the non-destructive examination of various cultural heritage objects. It allows analysis of elemental composition based on single-point measurements. However, large, or complex textiles require numerous analysis points to identify the materials used and correctly interpret the spectra. MA-XRF takes this type of research to the next level, as it is possible to visualise the element distribution over an entire mapped area. In this paper, we discuss the application of this technique to the study of complex and multi-layered textile objects from exceptional Belgian heritage collections, including two mitres attributed to Bishop Jacques de Vitry, dating between twelfth and thirteenth century, and two of the seven extremely fine medieval reliquary purses from Namur. These are very fragile, richly decorated textile objects whose current state of preservation is a major impediment to sampling. MA-XRF mapping was applied for the identification of the elements of different materials in a non-invasive manner, including metal threads, ink, dyes, and various materials used in illuminations. In addition to material identification, stratigraphic information was obtained from the visualisation of element distributions, and hidden structural details were discovered. MA-XRF was also tested on some areas with more relief, such as the embroidery and braid made with metal threads, and the undulated multi-layered structure of the parchment mitre. Even though the analyses here could not be carried out in optimal conditions, these locations could also be analysed, albeit at a lower resolution. Finally, the technique proved very effective as a tool for screening, allowing samples to be taken at a more informative and representative location and minimising sampling. [ABSTRACT FROM AUTHOR]

Scholars have long had difficulties when dealing with cross-time and cross-boundary issues in the Index of Sustainable Economic Welfare (ISEW) and Genuine Progress Indicator (GPI). This case study for Belgium is the very first that tackles these complexities by calculating two ISEW-variants with distinct time and boundary perspectives that are based on Fisherian or Hicksian income. Experiential welfare looks at what is currently experienced within domestic borders, whereas the benefits and costs of present activities also include the welfare impacts shifted in time and space. The former construct only registers present ecological costs within borders and does not include capital changes, while the latter includes capital changes and ecological cost-shifting. As we find substantial ecological cost-shifting, we suggest to move forward with the latter concept. Next, the paper introduces a number of advances to the ISEW-methodology. These include the introduction of a sufficiency threshold for consumption expenditures when accounting for the diminishing marginal utility of income, the adoption of a consumption footprint view for the emissions embodied in trade with an additional focus on the climate impacts of aviation and shipping and the inclusion of the shadow economy. Finally, we propose to look beyond the aggregate ISEW and adopt a disaggregated approach to evaluate economic performance in detail. [ABSTRACT FROM AUTHOR]

This paper estimates conditional demand models to examine the impact of immigration and different measures of offshoring on the labour demand and demand elasticities of native workers in four different types of occupational groups: managers/professionals, clerical workers, craft (skilled) workers and manual workers. The analysis is conducted for the period 2008–2017 for four economies Austria, Belgium, France and Spain. Our results point to important and occupation-specific direct and indirect effects: both offshoring – particularly services offshoring – and immigration have negative direct employment effects on all occupations, but native clerks and manual workers are affected the most, and native managers/professionals the least. Our results also identify an important elasticity-channel of immigration and offshoring and show that some groups of native workers can also gain from globalisation through an improvement in their wage-bargaining position. Overall, our results indicate a deterioration in the bargaining power of native manual workers arising from both immigration and offshoring and an improvement in the bargaining position of native craft workers. [ABSTRACT FROM AUTHOR]

This study examines how non-profit organizations that engage in advocacy gain their legitimacy in the eyes of their target group of vulnerable citizens. The existing body of literature shows that these organizations are challenged in their pursuit of citizen legitimacy, defined as the extent to which their constituent target group perceives the organization as justified, accepted, and appropriate. This paper draws on the results of qualitative research in government-funded non-profit community work organizations that develop advocacy activities to influence policymakers. We interviewed community workers and their target group of citizens in four community centers in Flanders, the northern region of Belgium. We show that community workers engage in practices to enhance both the input and throughput legitimacy of their advocacy activities. More specifically, they construct safe spaces through informality, ensure proximity by taking care of individual needs, and collectivize individual needs. [ABSTRACT FROM AUTHOR]

This paper analyzes the impact of automatic wage indexation on employment. To boost competitiveness and increase employment, Belgium suspended its automatic wage indexation system in 2015. This resulted in a 2% fall in real wages for all workers. In the absence of a suitable control group, we use machine learning for the counterfactual analysis. We artificially construct the control group for a difference-in-difference analysis based on the pre-treatment evolution of treated firms. We find a positive impact on employment of 1.2%, which corresponds to a labor demand elasticity of − 0.6. This effect is more pronounced for manufacturing firms, where the elasticity reaches − 1. These results show that a suspension of the automatic wage indexation mechanism can be effective in preserving employment. [ABSTRACT FROM AUTHOR]

Pilot tests for (semi-)autonomous transport via inland waterways are already taking place in Belgium and other European countries. However, the full commercial implementation of autonomous inland shipping might be hampered by liability issues. The allocation of liability, especially extracontractual liability, is an important concern for shipowners who want to invest in autonomous barges, and for other ecosystem actors. For this reason, a balanced risk distribution framework could boost the investment decision. A legal analysis of the current laws and regulations is necessary to evaluate whether they can be applied to new autonomous systems. The research approach consists of two steps. First, an in-depth literature review is carried out to determine whether extracontractual liability research has already been conducted and to highlight the gaps in autonomous inland waterways transport studies. Once it is proved that the vast majority of the research focuses on technology, it can be affirmed that there is a need to inquire about extracontractual liability. In the second part, thus, the two international Conventions on liability limitation and collision in inland navigation are examined. [ABSTRACT FROM AUTHOR]

Parenting perfectionism, especially the dimension of perfectionistic concerns—preoccupation with self-criticism including concern over mistakes and doubts about own behaviors—, has been shown to be a weighty factor for parental burnout. Drawing on the Balance between Risks and Resources (BR2) theory of parental burnout, this paper examines whether emotional competence could moderate/buffer the effect of parenting perfectionism on parental burnout. We investigated this question in two independent samples of parents collected in Belgium (N = 347) and Poland (N = 377). The results of both studies show that emotional competence cancels out the detrimental effect of perfectionistic concerns on parental burnout. Beyond its contribution to parenting perfectionism and emotional competence literatures, the present article also provides further evidence of the potential of the BR2 theory of parental burnout. [ABSTRACT FROM AUTHOR]

The Family Perceptions of Physician-Family Caregiver Communication scale (FPPFC) was developed to assess quality of physician-family end-of-life communication in nursing homes. However, its validity has been tested only in the USA and the Netherlands. The aim of this paper is to evaluate the FPPFC construct validity and its reliability, as well as the psychometric characteristics of the items comprising the scale. Data were collected in cross-sectional study in Belgium, Finland, Italy, the Netherlands and Poland. The factorial structure was tested in confirmatory factor analysis. Item parameters were obtained using an item response theory model. Participants were 737 relatives of nursing home residents who died up to 3 months prior to the study. In general, the FPPFC scale proved to be a unidimensional and reliable measure of the perceived quality of physician-family communication in nursing home settings in all five countries. Nevertheless, we found unsatisfactory fit to the data with a confirmatory model. An item that referred to advance care planning performed less well in Poland and Italy than in the Northern European countries. In the item analysis, we found that with no loss of reliability and with increased coherency of the item content across countries, the full 7-item version can be shortened to a 4-item version, which may be more appropriate for international studies. Therefore, we recommend use of the brief 4-item FPPFC version by nursing home managers and professionals as an evaluation tool, and by researchers for their studies as these four items confer the same meaning across countries. [ABSTRACT FROM AUTHOR]

In 2015 the Council of Europe introduced a new criminal law convention to address organ trafficking. The main focus of the Council of Europe Convention against Trafficking in Human Organs is the crime of illicit organ removal. The act of illicit organ removal is also criminalised under international human trafficking instruments that consider it as a form of exploitation of a living organ donor. As both legal frameworks rely on two key concepts to determine if the respective crimes occurred, namely, valid consent to organ removal and the presence of monetary benefits, a clear overlap exists when an organ is removed from a living donor. The question arises as to whether the illicit organ removal, based on the same factual circumstances and material evidence, is sufficiently distinct for an offender to be prosecuted under both regimes simultaneously or in separate criminal proceedings, without violating the principle of ne bis in idem. This paper aims to answer that question by (1) examining the crime of illicit organ removal under both criminal regimes and (2) analysing Belgian criminal law frameworks on human trafficking and organ trafficking in the context of the applicability of the principle of ne bis in idem as developed by the European Court of Human Rights and the Court of Justice of the European Union. This analysis reveals the complexity of the issue. It also confirms the proximity of the legal definitions of both types of crimes, resulting in a considerable overlap and a clear risk of double prosecution and punishment. On the basis of these findings, recommendations are formulated on how to harmonise the application of both trafficking frameworks so as to minimise that risk. [ABSTRACT FROM AUTHOR]

This paper analyses the wage effects of educational mismatch by workers' origin using a sizeable, detailed matched employer–employee dataset for Belgium. Relying on a fine-grained approach to measuring educational mismatch, the results show that over-educated workers, regardless of their origin, suffer a wage penalty compared to their well-matched former classmates. However, the magnitude of this wage penalty is found to vary considerably depending on workers' origin. In addition, the estimates show that origin-based differences in over-education wage penalties significantly depend on both demographics (workers' region of birth, education, gender and tenure) and employer characteristics (firm size and collective bargaining). To our knowledge, the role played by these different moderating variables has been either little or not explored in this context before. [ABSTRACT FROM AUTHOR]

In Northwestern Europe, Germany, France, the Netherlands, the UK and Belgium constitute the biggest five potato producers, with total potato crop production around 60% of EU-28 production before Brexit. Soil and climate conditions are highly favourable for potato growth in this region. Production is under driving forces of (i) the potato processing industry, particularly in Belgium; (ii) the innovation for fresh potato in the UK, France and Germany; (iii) the leadership of Germany and the Netherlands for starch potato; and (iv) the dominance of the Netherlands for seed production. Based on an industrial agri-food production system, the region has the highest potato yield levels worldwide and developed relevant trade networks for export of seed, fresh and processed potato products in and outside Europe. Conventional and intensive potato production is widespread over the region, whilst organic production started to develop in Germany and France. Whether the coming decades will be as successful as the last ones for sustainable potato production will depend on how the sector and stakeholders of the whole potato value-chain will overcome new issues and challenges. These are mainly soil quality and health conservation, consequences of climate change, increasing bans on the use of plant protection products, tightening environmental standards, food waste reduction and increasing trade tensions hampering the flow of potatoes around the world. After a detailed description of the potato production in the region, this paper contains a SWOT analysis aiming to identify potential solutions to overcome environmental, technical, economic, political and societal issues in the region for sustainable potato production in the coming years and decades. [ABSTRACT FROM AUTHOR]

Aim: The goal of this paper is to analyze the COVID-19 policies of 10 European countries, including Sweden, Finland, Norway, Italy, France, Germany, Poland, Belgium, the Netherlands, and Hungary, with a time-series policy analysis tool. Subject and methods: The results of the COVID-19 policy analysis are based on a single time-series indicator, or daily population mortality rate: the number of COVID-19 daily cumulative deaths divided by the population in millions. The lower the score, the better the policy. Although many experts believe that the COVID-19 policy outcome analysis is premature, time series analysis is an excellent analysis that can provide information on the progress and transition of policy outcomes. In other words, the proposed time series analysis tool allows policymakers to identify and quantify when mistakes were made during the on-going COVID-19 pandemic. Results: The COVID-19 policy analysis discovered many useful facts. Sweden failed due to the herd immunity approach. Hungary made a fundamental mistake in COVID-19 tactics. Countries such as Sweden, Hungary, Belgium, and Poland showed time-series changes that differed from the others. Conclusion: Public health interventions can play a key role in mitigating the COVID-19 pandemic. The proposed policy analysis tool, hiscovid demonstrated the effectiveness of the time-series score behavior for discovering when policymakers made mistakes. [ABSTRACT FROM AUTHOR]

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INSIDER (Improved Nuclear SIte characterization for waste minimization in D&D operations under constrained EnviRonment) was a European project funded under the H2020-EURATOM programme and launched in June 2017. The project was coordinated by the French Commissariat à l'énergie atomique et aux énergies alternatives (CEA), it had a total duration of 4 years and covered a budget of 4 M€. INSIDER's work was performed by 5 technical working groups (WG) which brought together 18 institutions from 10 countries, leading to a total of 68 participating researchers. The objective of the project was to optimise the radiological characterisation of nuclear installations in constrained environments in order to obtain an accurate estimate of the content of contaminated materials as well as to optimise the quantity of contaminated materials to be treated as waste. The focus of this paper is on the statistical analysis of an interteam comparison of measurement results (dose rate, total gamma measurement, and gamma spectrometry) made in situ at the BR3 reactor, Belgium. [ABSTRACT FROM AUTHOR]

According to self-determination theory, individual well-being is universally dependent upon the satisfaction of three basic psychological needs: autonomy, competence and relatedness. This study set out to further elucidate the relationship between basic psychological need satisfaction (BPNS) and well-being across age by (i) more closely examining the age distribution of BPNS, and (ii) investigating whether BPNS is comparably associated with well-being across all ages, as predicted by the universality assumption, while taking into account variability in other demographic factors. A general population sample of Dutch speaking adults from The Netherlands and Belgium (N = 1709; Mage = 48.6 years, SD = 19.0, range 18–97) filled out a cross-sectional online or paper-and-pencil survey questionnaire, providing self-reports of BPNS and well-being, using the Basic Psychological Need Satisfaction and Frustration Scale and Mental Health Continuum-Short Form, respectively. Data analyses consisted of initial visual inspection using LOESS smoothed curve plotting, and subsequent model testing using multiple regression analyses. When correcting for other demographic factors, results showed a positive linear relationship between age and autonomy satisfaction, no significant relationship between age and competence satisfaction, and a slight positive cubic relationship between age and relatedness satisfaction (initial 'peak', followed by a slight decline and 'dip', and steady rise for later ages). All basic psychological needs factors were positively linked to well-being in all domains, with associations generally comparable between adults of different ages, thus lending support to the universality assumption of self-determination theory. Despite distinct age distributions, all three basic psychological needs seem important for maintaining a sense of well-being throughout life. [ABSTRACT FROM AUTHOR]

This paper presents two datasets obtained from laboratory experiments of urban flooding in a street network performed at the University of Liège. The experimental model represents a part of a synthetic urban district that consists of three inlets, three outlets and several three- and four- branches crossroads. The following experimental data was produced: (i) dataset 1: time-series of flow depths at model inlets and time-series of discharges at model outlets for a two-branch junction model, a two-branch bifurcation model and a district model. The datasets were generated by varying the upstream and downstream boundary conditions, i.e. flooding conditions; (ii) dataset 2 includes the same data type as dataset 1 complemented by 2D surface velocity measured using the non-intrusive LSPIV technique for eight urban form configurations in the district model. The collected data enable improving the understanding of the effect of urban forms on the urban flood processes. These two datasets are valuable for validating and improving numerical or analytical models of urban flooding and may contribute to flood risk management and flood-resilient urban design. Measurement(s) flow depth • Outflow discharge • Surface velocity field • Inflow discharge Technology Type(s) Ultrasonic sensor • Calibrated rating curve Q~H • Large Scale Particle Images Velocity (LSPIV) with a commercial camera LUMIX-GH4 • Electromagnetic flowmeters Factor Type(s) Flooding scenario • Model geometry • Scale factors Sample Characteristic - Organism Water Sample Characteristic - Environment laboratory environment Sample Characteristic - Location Belgium [ABSTRACT FROM AUTHOR]

This paper examines the effect of languages on corporate tax avoidance. We hypothesize and find that managers of firms in countries with languages that grammatically distinguish the future from the present (languages with a strong future time reference or FTR) perceive the potential future tax repayments and penalties to be more distant and therefore engage in more tax avoidance. Further tests exploiting the variation in language FTR within Switzerland and Belgium, which have different official languages in different regions but a single tax system, suggest that our findings are not driven by country-level differences in the tax system. We also provide evidence that U.S. firms with CEOs born in countries with strong FTR languages avoid more taxes than those with CEOs born in weak FTR countries, indicating that it is the CEO's native tongue that affects tax avoidance. Collectively, our findings highlight the importance of social norms in understanding corporate tax strategies. [ABSTRACT FROM AUTHOR]

This paper is concerned with the historical roots of gender equality. It proposes and empirically assesses a new determinant of gender equality: gender-specific outside options in the marriage market. In particular, enlarging women's options besides marriage—even if only temporarily—increases their bargaining power with respect to men, leading to a persistent improvement in gender equality. We illustrate this mechanism focusing on Belgium, and relate gender-equality levels in the 19th century to the presence of medieval, female-only communities called beguinages that allowed women to remain single amidst a society that traditionally advocated marriage. Combining geo-referenced data on beguinal communities with 19th-century census data, we document that the presence of beguinages contributed to decrease the gender gap in literacy. The reduction is sizeable, amounting to a 12.3% drop in gender educational inequality. Further evidence of the beguinal legacy is provided leveraging alternative indicators of female agency. [ABSTRACT FROM AUTHOR]

By 2040, over half a billion people globally are expected to have diabetes. This disease implies a loss in life quality and comes with a significant financial impact. To avoid prevalence increases in the main category of diabetes—type-2 diabetes (T-2D)—, preventive action among high-risk groups is necessary. Lifestyle and medical interventions with metformin among prediabetic individuals show strong potential to decrease or delay T-2D. The aim of this paper is to evaluate the cost-effectiveness and budget impact of a nation-wide implementation of these interventions, between 2020 and 2040, in Belgium. This is done through a dynamic, non-homogeneous, semi-Markov model which simulates prevalence and costs of a type of prediabetes (impaired glucose tolerance or IGT) and T-2D in Belgium. High-risk individuals are first screened; individuals with IGT then enroll in a lifestyle or metformin program. Compared to no intervention, both programs are very cost effective from the perspective of the health care system and cost-saving from a broader societal perspective. Both interventions require an initial, affordable government investment and later yield government savings. The lifestyle program is a cost-effective alternative to the metformin intervention and may yield additional benefits through, for example, improvements in mental health. [ABSTRACT FROM AUTHOR]

This paper explores the supply chain (SC) disruption impacts to the performance outcomes of a semiconductor company during the Covid-19 pandemic and proposes appropriate risk mitigation strategies to overcome the crisis. The research uses a single case study methodology and 24 SC employees from Belgium and Germany who take part in the survey. To measure the effect of SC disruptions to the firm's financial performance, some quarterly financial statement data are used from 2018 to 2021. The regression analysis results show that there is no significant impact of SC disruptions to the firm's productivity and non-financial performance. The paired samples t-test suggests that there is no significant change in the firm's financial performance before and during Covid-19 either due to the market's political and economic stability or the semiconductor company develops effective SC risk management strategies. [ABSTRACT FROM AUTHOR]

The extremal index is an important parameter in the characterization of extreme values of a stationary sequence. This paper presents a novel approach to estimation of the extremal index based on truncation of interexceedance times. The truncated estimator based on the maximum likelihood method is derived together with its first-order bias. The estimator is further improved using penultimate approximation to the limiting mixture distribution. In order to assess the performance of the proposed estimator, a simulation study is carried out for various stationary processes satisfying the local dependence condition D (k) (u n) . An application to daily maximum temperatures at Uccle, Belgium, is also presented. [ABSTRACT FROM AUTHOR]

It is often claimed that green walls (GW) and living wall systems (LWS) have a positive effect on urban air pollution problems if their plants composition is optimal (design of the LWS). An in-depth review of the knowledge on plants traits maximizing GW effects on air pollution shows that these might be hasty conclusions: there are still some important knowledge gaps. Robust conclusions can only be drawn for particulate matter (PM): the other pollutants are not analyzed by a sufficient number of studies. It can be concluded that leaves with hairs/trichomes are the most effective to capture PM. The rougher and the smaller the leaf is, the more PM it catches. The analysis of the plant composition of six LWS in Belgium indicated that these LWS supported a plant community dominated by only a few species, which do not exhibit in majority the most effective traits to maximize their PM capture. Regarding climbing plants, only three out of seven commonly used creepers in Belgium present hairs/trichomes on their leaves. Studies conducted on other pollutants and other traits are required to optimize the GW plant composition and to maximize their effects on air quality. [ABSTRACT FROM AUTHOR]

Since the late 1990s and early 2000s, in what can be called an 'integrationist wave', standardised integration requirements for naturalisation have become increasingly common in Europe. To examine the impact of such measures, I combine original ethnographic data on institutions involved in the implementation of citizenship policies in Belgium and the UK with a qualitative meta-analysis of existing ethnographic studies of the implementation of citizenship policies. I show how, in addition to introducing new obstacles to naturalisation, standardised requirements have also reduced the discretion inscribed in earlier procedures, albeit not uniformly across different cases. The integrationist wave could thus be understood not simply as the introduction of restrictive notions of integration, but also as the systemisation of earlier evaluation practices. I further show signs of a more recent tendency for states to retreat from examining the integration of candidates to citizenship, outsourcing the evaluation directly or indirectly to private actors. [ABSTRACT FROM AUTHOR]

The i-DREAMS project focuses on establishing a framework known as the 'Safety Tolerance Zone (STZ)' to ensure drivers operate within safe boundaries. This study compares Long-Short-Term-Memory Networks and shallow Neural Networks to assess participants' safety levels during i-DREAMS on-road trials. Thirty German drivers' trips and Forty-Three Belgian drivers were analyzed using these methods, revealing factors contributing to risky behavior. Results indicate i-DREAMS interventions significantly enhance driving behavior, with Neural Networks displaying superior performance among the algorithms considered. [ABSTRACT FROM AUTHOR]

Of the early Eocene amber deposits known across the world, Belgian amber has been mostly absent from the relevant literature. We reinvestigated amber held in the palaeobotanical collection of the Royal Belgian Institute of Natural Sciences, Brussels, which derived from three localities in Belgium that originated from two geographical areas (Leval-Trahegnies and Orp-le-Grand). Using Fourier transform infrared (FTIR) spectroscopy we show the close chemical relationship of Belgian amber to the early Eocene Oise amber from the Paris Basin, and highlight the potential effect of weathering on the amber chemistry. The amber derives from a very similar botanical source as the Oise amber (Combretaceae or Leguminosae-Caesalpinioideae), but from different coeval basins. The two Leval-Trahegnies localities provided amber that exhibit different stages of weathering (heavily fissured and crazed, darkened) and lacking any inclusions. The Orp-le-Grand locality provided the least weathered amber, with one amber piece containing two inclusions: a mite and a new genus and species of hemipteran (Cativolcus uebruum gen. et sp. nov.), and a second one that preserved the impression of insect wings pressed into the surface. [ABSTRACT FROM AUTHOR]

Manure is used as a source of nutrients and organic matter for agricultural lands, but its unbalanced use has unfortunately made nitrogen (N) and phosphorous (P) leakage to the environment quite common in Western Europe. One way to optimize the use of manure is variable rate (VR) application, wherein within field spatial variability of soil nutrient provision is accounted for. This work evaluated the economic and environmental benefits of a P-based VR manure application and compared it to an N-based uniform rate (UR) application. An on-line visible and near-infrared spectroscopy sensor was used to collect on-line spectral data from soils in two fields of 7.9 and 5.1 ha with barley and wheat, respectively, in Belgium. A calibration model to predict extractable P (P) in soil was developed by partial least squares regression. Based on the locally predicted P level, the P-fertilizer application rate was calculated. According to P2O5 content in manure, manure application rates were set based on the level of soil P measured with the on-line soil sensor. Based on application maps, a strip experiment was conducted to compare the efficiency of VR and UR treatments. The results showed that P-based VR manure application resulted in almost the same yield as the UR treatment; however, it saved the environment by reducing N by 44 kg/ha and 29 kg/ha, and P2O5 by 18 kg/ha and 12 kg/ha, when applied in the two fields. Since farmers received compensation from the manure providers for allowing the manure to be applied in their fields, the P-based VR manure application using less manure has resulted in a smaller gross margin than the N-based UR method, by which more manure was applied. However, if farmers had to pay for this application (as is the case in some European countries), a P-based VR manure application would result in positive gross margins. It is encouraged to adopt VR manure applications in arable crop production, as both economic and environmental benefits are feasible. [ABSTRACT FROM AUTHOR]

Purpose: Research on return to work (RTW) following transition-related gender-affirming care (GAC) is lacking. We aim to study the RTW outcomes and experiences of transgender and gender diverse (TGD) people during social and medical transition to understand their needs better and provide tailored support. Methods: In this convergent mixed-methods study, the questionnaires of 125 employed TGD people, who took steps in transition (social and GAC), were analyzed for personal- and work characteristics, medical work absences, RTW, support at work, and health literacy. In-depth interviews were held with twenty TGD people to explore perceived facilitators and barriers to RTW. Results: One hundred and nine participants reported an average of 38 sick days after GAC. The majority (90.2%) resumed their job at the same employer. Although TGD workers felt supported, their health literacy (55.1%) was lower compared to the general population. The qualitative data analysis revealed four major themes: (1) the need and access to information; (2) having multidisciplinary TGD allies; (3) the influence of the occupational position; (4) the precarious balance between work, life, and GAC. Especially participants with a low health literacy level experienced RTW barriers by struggling: (1) to find and/or apply information; (2) to navigate (occupational) health and insurance services. Conclusion: Our research has shown that RTW for TGD individuals is a multifaceted process, affected by personal factors, work-related elements, and the characteristics of the healthcare and social insurance system. Enhancing support for TGD people at work and their RTW requires a high need for centralized information and promoting health literacy while engaging relevant stakeholders, such as prevention services and employers. [ABSTRACT FROM AUTHOR]

Numerous representation studies suggest that political elites are responsive to the expressed preferences of their voters, but scholars in the field have called for experimental research on the topic to shed light on the underlying mechanisms. This paper responds to this call. Results from a survey experiment with members of parliament in Belgium show, for the first time, that an important mechanism driving responsiveness is opinion adaptation by political elites. Just like 'ordinary' citizens adapt their opinions when learning where their preferred party stands on an issue, politicians update their position when learning that it opposes the preferences of a majority of their electorate. This implies that elite responsiveness involves less discord between politicians' own preferences and voter preferences than is often assumed. [ABSTRACT FROM AUTHOR]

Estimates of the energy potential of the different energy sources are essential for modelling energy systems. However, the potential of biomass is debatable due to the numerous dimensions and assumptions embedded. It is thus important to investigate further the final potential to understand their implications. Therefore, this study analyses European studies assessing biomass potential and proposes a critical discussion on the different results to converge to a realistic range of potentials for 2030. Biomass is divided into four categories: forestry products, agricultural residues, energy crops and other waste, each with sub-categories. Belgium is used as a case study to highlight the convergences and divergences of the studies. Having a national case study allows for more precise analyses through in-depth comparisons with national data and reports. The potential estimates are compared with the current production for each category in order to have a better view of the gap to be bridged. From these national perspectives, the European potential can be better apprehended. The results show that the realistic potentials for 2030 for Belgium and Europe are somewhat in the lower range of the estimates of the different studies: from 30 to 41 TWh and from 2000 to 2500 TWh, respectively. The forestry biomass is already well exploited with a slight potential increase, while the agricultural residues present the most significant potential increase. The realistic potential for energy crops in Belgium turned out to be close to the minimum estimates. Indeed, the implications of those crops are considerable regarding the agricultural structure and logistics. This article emphasises that no energy potential is neutral, as it involves a specific system in terms of agriculture, forestry or waste management, with broader social, economic or environmental implications. Consequently, using one estimate rather than another is not a trivial matter; it has an impact on the system being modelled from the outset. [ABSTRACT FROM AUTHOR]

In 2019, a joint eight-variant model was published in which eight single nucleotide polymorphisms (SNPs) in seven Apis mellifera genes were associated with Varroa destructor drone brood resistance (DBR, i.e. mite non-reproduction in drone brood). As this model was derived from only one Darwinian Black Bee Box colony, it could not directly be applied on a population-overarching scale in the northern part of Belgium (Flanders), where beekeepers prefer the carnica subspecies. To determine whether these eight SNPs remained associated with the DBR trait on a Flemish colony-broad scope, we performed population-wide modelling through sampling of various A. mellifera carnica colonies, DBR scoring of Varroa-infested drone brood and variant genotyping. Novel eight-variant modelling was performed and the classification performance of the eight SNPs was evaluated. Besides, we built a reduced three-variant model retaining only three genetic variants and found that this model classified 76% of the phenotyped drones correctly. To examine the spread of beneficial alleles and predict the DBR probability distribution in Flanders, we determined the allelic frequencies of the three variants in 292 A. mellifera carnica queens. As such, this research reveals prospects of marker-assisted selection for Varroa drone brood resistance in honeybees. [ABSTRACT FROM AUTHOR]

Research has shown that gender role attitudes develop during adolescence; however, the relevant predictors remain a matter of debate. In adolescence, the school environment gains in importance. Thus, the present study investigates how students' and especially teachers' culture and composition predict the development of gender role attitudes in young adolescents. The study addresses this question using a sample of 7360 Flemish students (44.8% girls), who were surveyed three times after entering secondary education between 2012 (Mage = 13.14, SD = 0.56) and 2014. Latent change models reveal that boys' initial gender role attitudes are associated with the students' gender role culture; however, boys with more traditional gender role attitudes do not develop in an even more traditional direction at the beginning of secondary education. In contexts with a more privileged student SES composition, boys develop less traditional attitudes, while a traditional gender role culture among teachers supports the development of more traditional gender role attitudes among boys. Girls with more traditional gender role attitudes find themselves within student contexts with a more traditional culture. However, the development does not vary with the students' gender role culture. Overall, boys seem more susceptible to students' cultural and compositional characteristics. [ABSTRACT FROM AUTHOR]

Background: Energy cooperatives in Europe have become more prominent due to the growing interest in and development of renewable energy sources. Cooperatives are often seen as an instrument in the transition to a low-carbon future. The cooperative prosumer is gaining importance, taking on the role of both consumer and producer by setting up and joining electricity cooperatives as investors, shareholders and clients. As is the case with other cooperatives and social enterprises, there are tensions and trade-offs to be made between social, ecological and financial goals. To navigate these tensions and to work towards becoming a resilient institution, it is important that cooperatives preserve their support base made up of their members, who are both clients and shareholders. This study investigates the preference heterogeneity and motivations of members of a large energy cooperative in Belgium, by using stated-choice data from a Discrete Choice Experiment in combination with self-reported membership motives. Results: Despite the significant presence of member preferences for participation and democratic voting rights, the financial and above all the ecological motives seem to be most important for being a member of the energy cooperative. Based on the stated-choice data, we classify three member types: the financial, the ecological and the social–societal member type. We find a small discrepancy in motives between members who joined early and members who joined later. Where early members care most about ecological aspects, members who joined later have more societal and financial considerations. In terms of effect size and willingness to pay per kilowatt hour, ecological motives prove to be by far the most important factor for cooperative energy prosumers in our sample. In addition, the latent-class analysis shows that over half of the member sample belongs to the ecological motives class. Conclusions: Preference heterogeneity is present to an extent, but there is an overarching preference for sustainability. Though, cooperatives should be aware that their legal form may not be the only factor that drives membership. Rather, keeping high levels of renewable energy, competitive pricing and being an interesting investment opportunity may be key to cooperatives' resilience and further development on the energy market. [ABSTRACT FROM AUTHOR]

In Belgium, migrants from Sub-Saharan Africa (SSA) accounted for 45% of new heterosexual HIV infections in 2021, while only 1.5% of PrEP starters were of SSA descent. We explored the acceptance of PrEP and barriers towards PrEP uptake and use among SSA migrant and diaspora communities in Belgium using a participatory action research approach. Trained community researchers (CRs), involved in all phases of the study, co-designed and moderated group discussions (GDs) while simultaneously providing information on HIV and PrEP during workshops. Extensive summaries and field notes were analysed using reflexive thematic analysis. CRs were involved in data analysis, interpretation and reporting. We conducted seven GDs with 51 participants. We identified five major themes: (1) Participants had limited PrEP knowledge, which created feelings of surprise and annoyance about not being informed. This was partly explained by (2) the taboo and stigma that surrounds sexuality and HIV, which could shape PrEP acceptance. (3) Participants shared feelings of otherness due to experiences of racism and discrimination, also in relationship to HIV prevention. (4) PrEP was considered a high-threshold prevention tool, because of its perceived side-effects and its specialized service delivery. (5) Despite nuanced opinions about PrEP, all participants agreed that PrEP promotion should be mainstreamed, so everyone can make an informed decision. In conclusion, PrEP seemed acceptable among our participants. Our qualitative study provides insights into the intersecting barriers to accessing HIV services, showing that SSA diaspora communities are 'hardly reached' rather than 'hard to reach' by PrEP promotion messages. [ABSTRACT FROM AUTHOR]

Background: Documentation of drug related problems (DRPs) and pharmaceutical interventions (PIs) is essential for an objective evaluation of the pharmacist's contribution to pharmacotherapy. However, in Belgium, a nationally used classification system is not available, prohibiting structured and uniform documentation of DRPs and PIs. Aim: To develop and validate a national classification system for in-hospital clinical pharmacy activities, based on literature and field experience, specifically intended for routine registration. Method: Based on a literature review, a survey among Belgian hospital pharmacists and a stakeholder focus group, a first version of Be-CLIPSS (Belgian CLInical Pharmacy claSsification System) was developed. Inter-rater reliability of the DRPs and PIs was assessed. Additionally, its usability was reviewed. The system was further refined, followed by a second validation. Results: Both the survey and focus group discussion revealed little use of validated DRP and PI classification systems in Belgium, although these were considered highly desirable if practical and minimally time-consuming. The final classification system encompassed seven clinical pharmacy activities, grouped into four activity classes. The inter-rater reliability for the second activity class was substantial for the DRPs (κ = 0.737) and almost perfect for the PIs (κ = 0.872). The interpretability (86.4%), user-friendliness (61.4%), user satisfaction (84.1%), interest for use in daily practice (68.2%) and difficulty in correctly classifying the DRP and PI (31.8%) were assessed. Conclusion: Be-CLIPSS, a newly developed and partially validated classification system for DRPs and PIs, was found to be user-friendly, with a good interpretability and user satisfaction, resulting in a high interest for use in daily practice. [ABSTRACT FROM AUTHOR]

Public holidays have been associated with SARS-CoV-2 incidence surges, although a firm link remains to be established. This association is sometimes attributed to events where transmissions occur at a disproportionately high rate, known as superspreading events. Here, we describe a sudden surge in new cases with the Omicron BA.1 strain amongst higher education students in Belgium. Contact tracers classed most of these cases as likely or possibly infected on New Year's Eve, indicating a direct trigger by New Year celebrations. Using a combination of contact tracing and phylogenetic data, we show the limited role of superspreading events in this surge. Finally, the numerous simultaneous transmissions allowed a unique opportunity to determine the distribution of incubation periods of the Omicron strain. Overall, our results indicate that, even under social restrictions, a surge in transmissibility of SARS-CoV-2 can occur when holiday celebrations result in small social gatherings attended simultaneously and communitywide. [ABSTRACT FROM AUTHOR]