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This book presents extensive and up-to-date information on the anti-proliferative properties of various plant seeds for their application in pharmaceutical industry and medicinal research. This information is imperative for understanding and developing high quality products from the seeds.The book provides insights about anticancer and antitumour activities present in seeds. Different chapters cover the traditional knowledge as well as recent innovations in various seeds, such as prune, pumpkin, grape fruit, sesame, sunflower, bitter gourd, papaya, mango, apple, black plum, cumin, water melon, musk melon, cotton, carambola, pear, cardamon, moringa, wallich, Chinese cabbage, pistachio, etc. and their bioactivities for the applications in cancer and malignancy proliferation. The book introduces the readers to seed as a bioactive compound, and delineates the various health effects. It further explains the relation between the different metabolites and their effect on cell proliferation. Finally the book goes on to explain different seeds and their specific anti-cancer properties. This book is useful for students and researchers of pharmacology, botany and cancer research. It also caters to industry experts in pharmaceutical sciences.

This innovative book offers a multidimensional exploration of the epistemological foundations of psychiatry and its major disorders. By emphasizing the importance of phenomenology in unravelling the intricate interplay between basic categories of human experience and neurobiological processes, it advocates for a shift in both psychiatric research and clinical practice. Phenomenological Neuropsychiatry presents psychiatry as a hybrid discipline that synthesizes subjective mental experiences with objective neuroscientific findings and forms an integrative and interdisciplinary structure that provides a dialectical bridge between understanding, compassion, and explanation. The first section of the book presents the lived experience of psychosis and argues for a more inclusive approach to mental health issues. The second section examines the ways in which psychiatric knowledge is constructed and the unique challenges posed by combining understanding and explanation of mental disorders. Section three sheds light on how disruptions in bodily experiences, memory processes, and self-perception can contribute to the development and manifestation of psychiatric issues. The following section discusses disorders of mood and anxiety, including the phenomena of depression, obsessions, and depersonalization. The fifth and final section provides an in-depth examination of psychotic disorders. It covers a range of topics, such as timing, intentionality, self-monitoring of action in schizophrenia, and the neurobiology of prodromal psychosis. As a singular work dedicated to revitalizing and advancing cross-fertilization between psychiatry and phenomenology, this groundbreaking book clears the foggy operationalized clusters of mental symptoms that may obscure diagnosis and treatment and argues for systematic integration of patient subjectivity and collaboration in clinical research. It features an authorship of the leading clinicians and thinkers from throughout the world in psychiatry, psychology, neuroscience, social sciences, and philosophy. Phenomenological Neuropsychiatry: How Patient Experience Bridges the Clinic with Clinical Neuroscience is a major contribution to the clinical literature and a must-read for psychiatrists, neurologists, psychologists, and professionals and students from other disciplines concerned with absorbing a deeper understanding of psychiatric disorders.

This book examines women's behavioral health (defined as alcohol, drug use, and mental health) problems from a population or public health perspective. It provides the current state of knowledge for women's behavioral health and examines the need for behavioral health services and implications for policy. It also reviews major issues in the organization, financing, and provision of women's behavioral health services. Global and national studies show that women are nearly twice as likely as men to have selected mental disorders. There also has been increasing attention to the social, behavioral, institutional, and economic determinants of health that result in service inequities for women in the United States compared to women in other countries. This textbook highlights mental and substance use disorders of particular concern to women, emphasizes services research issues in women's behavioral health, incorporates the social determinants of health, and provides a discussion of these critical issues from an interprofessional and interdisciplinary public health perspective. It also presents an overview of the epidemiology of mental and substance use disorders across the lifespan of women and service delivery issues from a population and system-level perspective. Applied services research chapters comprise the book's 14 chapter contributions that are organized into three parts: Part I. Framing Women's Behavioral Health; Part II. Selected At-Risk Populations; and Part III. Services Delivery issues. Women's Behavioral Health: A Public Health Perspective is a textbook for advanced undergraduate and graduate students in many academic disciplines, including the social and behavioral sciences, public health, women's studies, medical anthropology, and medical sociology. It also is useful for postdoctoral students in public health, population health, and the health professions. This volume can serve as a reference book for academicians and researchers in community and social psychology, community health, community nursing, community and preventive medicine, and public health; practitioners and policymakers at various levels of government; and behavioral health professionals at mental health and substance use programs in various national and global healthcare organizations.

This book is a comprehensive exploration of the science and clinical applications of fasting, with a particular focus on its effects on body weight and metabolic disease risk factors. It delves into various fasting methods, including time-restricted eating, intermittent fasting, alternate day fasting, and periodic fasting.The key concepts explored in this book include the physiological and cellular adaptations to different types of fasting, their impact on body weight and metabolic health, and their potential role in longevity, aging and disease prevention. The book addresses critical questions such as: What are the safety and efficacy of time-restricted eating? How does alternate day fasting affect body weight and metabolic disease risk factors? What are the evolutionary perspectives explaining the clinical benefits of periodic fasting? And how effective is periodic fasting in treating human chronic diseases? This book is aimed at healthcare professionals, researchers, nutritionists, and anyone interested in understanding the science behind fasting. Readers with a scientific or professional background will appreciate the rigorous research and clinical studies presented in this book. They will learn about the latest findings in this field and gain a deeper understanding of how different types of fasting can impact health, wellbeing and aging.

This book offers a new look at well-being from a multidisciplinary standpoint. Research from industry clearly indicates that factors such as creativity, critical awareness, well-being, interdisciplinary understanding of positive psychology, and the ability to form strong relationships will determine the viability of organizations as collectively we enter the second half of the twenty-first century. Thus, a sound understanding of how these facets become melded into entrepreneurship, the workplace environment, and creative innovation is a requirement for individuals in the workplace. With a dearth of information about these facets as individual components and as a collective whole, this book draws these elements of overall well-being into a multidisciplinary focus. Thus, with chapters covering diverse fields such as philosophy, education, economics, mathematics, and medicine, the book offers a fresh approach to how positive psychology impacts entrepreneurship.

This book is about access to mental health care in South Asia. South Asia consists of eight countries with low and middle-income backgrounds. The region contains a combined population of about 2 billion, making up about a quarter of the global population. The people of this region share common cultures, beliefs, and behavioral patterns regarding physical and mental health. Among them, about 15% (about 300 million) have been suffering from common mental disorders. However, there is a persisting high treatment gap for mental illness in the region. Hence, despite having a mental illness, only a small percentage of the population is able to have access to essential mental healthcare. Though governments are trying to bridge the gap by improving mental health policies and programs, it is still a major challenge delivering mental healthcare to all people in need. Due to the income category and dual disease burden of the countries, there are some additional enduring challenges like poor funding and research, inadequate and inequitable manpower, huge out-of-pocket expenses, poor mental health literacy, income disparity, and high stigma. This book aims to highlight the issues related to accessing mental health services in a densely populated low and middle-income setting. This book is the first of its kind in comparing and contrasting the delivery status of mental health services in South Asian countries.

Kinder- und Jugendpsychiatrie und Psychotherapie und Kinder- und Jugendlichenpsychotherapie haben in den letzten Jahren in der Forschung und Versorgung eine enorme Entwicklung gemacht. Durch die Einführung des Grundständigen Psychotherapiestudiums und der damit verbundenen Einführung einer fachspezifischen Weiterbildung in Kinder- und Jugendpsychotherapie, wird es zukünftig zwei heilberufliche Weiterbildungsgänge im Bereich der psychischen Gesundheit von Kindern und Jugendlichen geben. Die Neuauflage der Kinder- und Jugendpsychiatrie und Psychotherapie mit zahlreichen neuen Themen und fast komplett neuen Texten, spiegelt diese Entwicklung wider. Hierfür wurde das Herausgeberboard und das Autorenteam deutlich erweitert. Ausgewiesene Kinder- und Jugendlichenpsychotherapeutinnen und Psychotherapeuten sind gleichberechtigte Mitherausgeber. Insofern steht das Buch in der Tradition des Springer-Referenzlehrbuchs, ist aber dennoch weit mehr als eine dritte Auflage der Kinder- und Jugendpsychiatrie und Psychotherapie, denn hier wird kooperativ und interdisziplinär das Fachgebiet der Psychiatrie und Psychotherapie des Kindes- und Jugendalters präsentiert. Die Fülle an Information und Wissen ist ein unerlässliches Werkzeug für die tägliche Arbeit von Assistenzärzt•innen, Fachärzt•innen, Assistenzpsychotherapeut•innen in Fachweiterbildung Kinder- und Jugendpsychotherapie, Kinder- und Jugendlichenpsychotherapeut•innen in Ausbildung, Psychotherapeut•innen und Psycholog•innen und Sozialarbeiter•innen, auch in angrenzenden Fachgebieten. Das Buch beschreibt Schulen übergreifend die am besten geeigneten Therapieverfahren und bietet einen evidenzbasierten Handlungsleitfaden für alle, die in ihrem beruflichen Leben mit Kindern und Jugendlichen mit psychischen Störungen zu tun haben. Bedingt durch diese inhaltliche Ausweitung und angesichts der Fülle neuen Wissens, wurde zwar die klare Struktur und didaktische Aufbereitung im Lehrbuch beibehalten, gleichzeitig wurde das Buch in zwei Teile aufgeteilt. Ein allgemeiner Teil und ein spezieller störungsspezifischer Teil wird in zwei Bänden präsentiert, die durch die gleiche Struktur und didaktische Merkmale alle Leser•innen bei der Orientierung im Text unterstützen.

This book focuses on ocular manifestations of general human diseases with chapters divided according to the human organ system. Specialists in each field detail individual illnesses and ophthalmologists present an overview of ocular complications of these diseases. Manifestations of vascular, endocrine, autoimmune, rheumatological, pulmonary, gastrointestinal, hematological, infectious, skin, neurological, sexually transmitted and cancer diseases are discussed in detail throughout the book. Ocular Manifestations of Systemic Diseases is a highly illustrated guide with the basic data presented in clear tables and graphs with a further reading lists included for each topic. Ophthalmologists and experts in other fields, including general practitioners, will find this book to be an essential resource for their clinical and academic activities.

This book shows how psychological and social interventions can help people with psychosis. It brings together both theoretical chapters that contribute to the reconceptualization of psychosis and clinical cases illustrating how contemporary psychotherapeutic intervention models can be applied in the treatment of this mental health condition, with reflections, strategies and practical guidelines demonstrating how these models can inform professional practice in mental healthcare. Chapters brought together in this volume aim to reflect a paradigm shift in psychosis care. They present person-centered models that lead to a way of seeing, understanding and treating psychosis that is very different from the traditional biomedical model. Current authors and approaches are revolutionizing an outdated model trapped in purely pharmacological actions and tautological explanations of a biological nature, where symptom control is the basic and fundamental form of approach, and in which psychotherapeutic actions take second place as subsidiary to the former. Approaches such as Acceptance and Commitment Therapy, Acceptance and Recovery Therapy by Levels, Open Dialogue, Compassion-Centered Therapy or the Hearing Voices movement, to name but a few of those presented in this book, represent a journey of self-knowledge and learning for those recovering from psychosis, and have an intense transformative potential for the therapeutic team. The fundamental principle that guides this book is to share models belonging to psychology that aim at personal development while respecting the needs, values and goals of each person, and that can be adopted by any professional or student of clinical psychology, psychiatry, nursing, social work or any other discipline searching for more humanistic approaches to treat psychosis.

This book reviews the relationship between cytokines, glia, and neurons in the pathophysiology of neuropsychiatric disorders and examines the mechanisms of action of the drugs used for the treatment of these disorders. Increasing evidence has suggested that glia perform important roles in various brain functions, but much remains to be learned about these crucial cells and their interplay with neurons. In addition, a better understanding of the interaction between inflammatory mediators, such as cytokines, and the activated immune response will be of critical importance for the development of new therapeutic strategies. These key areas are the focus of this book, which documents the latest research findings in the field. Evidence is provided for the role of inflammation-induced toxic metabolites from the tryptophan pathway in a wide range of neuropsychiatric disorders, including depression, schizophrenia, and Alzheimer's disease. In presenting state of the art knowledge on the interactions between cytokines, glia, and neurons, the book will help to pave the way for the development of novel targets for the prevention and treatment of neuropsychiatric disorders.

This book provides a comprehensive overview of various chronic diseases - including their clinical characteristics, diagnostic methods, treatment options, and recent research findings - with a special focus on the psychosexual impacts of these conditions on patients and their partners. Each chapter in the book is dedicated to a specific chronic illness, examining its impact on the patient's sexual health and relationships. The book starts with an overview of the disease and its management, including both traditional and contemporary therapies, diagnostic tools, and international research studies. This is followed by a thorough discussion of the psychosexual consequences of the disease, along with the potential interventions that a multidisciplinary healthcare team can offer to provide comprehensive support to the patient. The book's primary objective is to improve healthcare professionals'approach to chronic patients by emphasizing the importance of addressing the patient's sexual health and intimacy. By acknowledging and addressing these aspects of the patient's life, healthcare providers can offer more holistic and effective care, leading to better patient outcomes. Overall, this book serves as a practical and essential guide for healthcare professionals seeking to enhance their knowledge and understanding of the psychosexual impacts of chronic illnesses. It is a valuable resource for those looking to provide compassionate, patient-centered care to those living with chronic conditions.

This book presents the ‘state of the art'of biomarkers research in neuropsychiatric conditions, from dementia to eating disorders, as well as providing methodological, practical and ethical issues related to the development of biomarkers. Biomarkers have revolutionized clinical research and practice in most fields of medicine, but psychiatry has lagged behind. However, in the last decade, there has been a growing expectation that biomarkers will advance and, ultimately, reframe psychiatry research and practice. Biomarkers might inform about diagnosis, therapeutics, prognosis, contributing to a ‘personalized medicine'. Understanding their meaning, possibilities and limitations will help clinicians, researchers and students in the related areas navigate and excel in the challenging and ever changing field of neuropsychiatric disorders.

This book aims to provide the reader a neuroscientific understanding surrounding a very simple question: how do we learn not to fear? Exploring answers to this question is very important for two reasons. First, learning about the neural mechanisms of fear extinction is of relevance to everyone's life - it is such a basic yet relevant question to our daily experiences. Therefore, understanding brain mechanisms of fear and its regulation is essential from a basic neuroscience point of view. Second, excessive fear and the inability to regulate its expression is one of the hallmarks of fear-, anxiety-, trauma-, and stressor-related psychopathologies. And as such, learning about how fear is acquired, stored, expressed, and regulated could help advance our understanding of the etiology of psychopathology, the maintenance of symptoms pertaining to failure to regulate fear, and could help us develop novel therapeutics to equip providers and patients with the tools to better quell their fears.The contributions contained in this book are provided by experts in the fields of basic and clinical neuroscience, experimental and clinical psychology, and neuropsychiatry. The contributions are organized to start the reader with basic definitions of how we define fear, how we study its neural circuits at the molecular and cellular levels, how to study human behavior and the brain using state-of-the art experimental and statistical tools, to how much fear contributes to psychopathology. This volume ends with current advances aimed to enhance the capacity to extinguish fear; a clinical result that would aid in the treatment of multiple psychiatric disorders, followed by a discussion on future directions of this highly important and relevant field.

The handbook examines the latest research and clinical advancements in assessing and treating ADHD (attention deficit hyperactivity disorder) across the lifespan. It synthesizes the most current research data and trends combined with best-practice interventions to form a comprehensive, state-of-the-art resource. The handbook identifies the most relevant, effective treatments for individuals with ADHD. Key areas of coverage include: Core symptoms of ADHD in minority children. Lifestyles for children with ADHD. Digital interventions for children and adolescents with ADHD. Telemedicine to manage ADHD across the lifespan. Healthcare use and costs for adults with ADHD. The Clinical Handbook of ADHD Assessment and Treatment Across the Lifespan is an essential reference for researchers, professors, and graduate students as well as clinicians and other professionals across such interrelated disciplines as clinical child, school, and developmental psychology, child and adolescent psychiatry, social work, rehabilitation medicine/therapy, pediatrics, and special education.

This book provides an overview on current trends and developments in precision nutrition and personalized health preservation, focussing on a field which is undergoing rapid change. Today, personalized strategies contrast generally accepted guidelines for specified groups and improved health and disease markers are shifting health care toward preventive strategies. At the same time, advances in food additives, nutraceuticals, functional, and medical foods are breaking down the traditional domains of health-related disciplines. This book aims to provide an overview on these processes, discusses arising problems, and provides an outlook on the future of personalized health care and the role of precision nutrition. It covers preliminary thoughts on what has been achieved and focusses on developments in the area of metabolic diseases, aging, and neurology. The book is intended as a primer in the field of precision nutrition and is aimed at researchers, clinicians, and students in health-related disciplines, who would like to get insights into current trends and developments in this area

The book provides a clear and comprehensive description of both personal and clinical recovery in severe mental disorders, including schizophrenia and related disorders, and mood disorders such as major depression and bipolar disorders. Divided into two main parts: recovery in schizophrenia and related disorders, and recovery in mood disorders, it offers a broad overview of the factors associated with better or worse outcomes in terms of recovery, as well as the rates (how many people affected by mental disorders may gain recovery), and the time course (how long people affected by mental disorders take to recover) of recovery. It also discusses in detail the pharmacological and psychosocial interventions that can be considered recovery-oriented. Covering the main aspects of recovery in major mental disorders, the book is intended for professionals, scholars, students and anyone interested in mental health.

This book provides a reference guide describing the current status of medication in all major psychiatric and neurological indications, together with comparisons of pharmacological treatment strategies in clinical settings in Europe, USA, Japan and China. In addition, it highlights herbal medicine as used in China and Japan, as well as complementary medicine and nutritional aspects. This novel approach offers international readers a global approach in a single dedicated publication and is also a valuable resource for anyone interested in comparing treatments for psychiatric disorders in three different cultural areas. There are three volumes devoted to Basic Principles and General Aspects, offering a general overview of psychopharmacotherapy (Vol. 1); Classes, Drugs and Special Aspects covering the role of psychotropic drugs in the field of psychiatry and neurology (Vol. 2) and Applied Psychopharmacotherapy focusing on applied psychopharmacotherapy (Vol. 3). These books are invaluable to psychiatrists, neurologists, neuroscientists, medical practitioners and clinical psychologists.

This book is a practical guide in understanding how to prevent HIV transmission, to recognize risk behaviors, and to add something else to their repertoires. It aims to empower clinicians and provide a sense of security and competence with the recognition and understanding of some of the psychiatric illnesses that complicate and perpetuate the HIV pandemic that continue to persist throughout every area of the world despite the magnitude of the progress that has transformed the illness from a rapidly fatal to chronic illness that is no longer life-limiting. Missing in most of the literature on HIV is the subtle, and sometimes not so subtle, contribution of psychiatric symptoms, psychiatric illness, and risk behaviors that drive the pandemic and serve as catalysts for new infections. This practical guide provides state-of-the-art understanding of not only prevention but also a way to recognize risk behaviors, psychiatric symptoms, and psychiatric illnesses that will demystify and decode the sometimes enigmatic and frustrating reasons for nonadherence with diagnostic procedures and life-saving treatments and care. All behaviors and pathology are covered as well as the resources and treatments available. The goal of this text is to refresh knowledge on the current state of psychiatric illness management among people living with HIV, to provide a concise volume on the psychiatric aspects of HIV prevention and treatment that substantially impact the overall care of the patient, and to help understand the psychiatric catalysts of the pandemicWritten by experts in the field, HIV Psychiatry: A Practical Guide for Clinicians provides enduring guidance to medical and other professionals caring for complicated clinical patients as they face ongoing challenges in working with persons with HIV and AIDS.

Burnout and trauma related employment stress (TRES), which includes compassion fatigue, secondary traumatic stress, and vicarious trauma, are increasing in prevalence as attrition rates, mental health disturbances, and suicide rates are climbing for those in the helping professions. This book highlights the imperative for prevention and early intervention using acceptance and commitment strategies. It includes cognitive, acceptance, and mindfulness techniques to assist the individual in achieving goals through values-based living. Among the topics discussed: Definitions of Burnout and TRESPrevalence rates of burnout and TRES in the helping professionsMindfulness and acceptance practicesDefusion and cognitive techniquesValues based goal settingOrganizational responsibilities and strategiesAssessment resources Burnout and Trauma Related Employment Stress will be a valuable resource for clinicians working with those experiencing the symptoms of TRES and burnout, as well as the individuals themselves.

Therapieresistente depressive und bipolare Störungen stellen ungebrochen eine klinische Herausforderung dar: Therapeutisches Nichtansprechen bzw. Therapieresistenz depressiver und bipolarer Erkrankungen sind nicht nur häufig, sie erfordern oft auch eine stationäre Behandlung. Für Betroffene und Angehörige bedeutet das erhebliche Einschränkungen der Lebensqualität und der sozialen und beruflichen Funktionsfähigkeit. Therapieresistente Verläufe verursachen gleichzeitig sehr hohe Behandlungskosten.Um dieser Herausforderung zu begegnen, steht heute ein breites Spektrum pharmakologischer, psychotherapeutischer und psychosozialer Behandlungsmöglichkeiten zur Verfügung, das spezielle Kenntnisse und Erfahrungen voraussetzt. In diesem Buch stellen daher namhafte ExpertInnen in kurzen, prägnanten Kapiteln wissenschaftlich fundiert und mit hohem Praxisbezug den aktuellen Wissensstand dar und bieten Leitlinien für die Behandlung in Klinik und Praxis.Dabei werden auch neue Methoden, wie weiterentwickelte Hirnstimulationsverfahren, Chancen und Grenzen pharmakogenetischer Methoden zur präziseren Therapieempfehlung („bedside genotyping“), neue psychotherapeutische und pharmakologische Ansätze sowie innovative integrierte Versorgungsformen berücksichtigt. Das Buch richtet sich an PsychiaterInnen, NervenärztInnen, PsychotherapeutInnen und PsychologInnen, insbesondere im stationären Setting, aber auch in spezialisierten Praxen, sowie WissenschaftlerInnen von Forschungseinrichtungen und Industrieunternehmen.

This book provides a structured and analytical guide to the use of artificial intelligence in medicine. Covering all areas within medicine, the chapters give a systemic review of the history, scientific foundations, present advances, potential trends, and future challenges of artificial intelligence within a healthcare setting. Artificial Intelligence in Medicine aims to give readers the required knowledge to apply artificial intelligence to clinical practice. The book is relevant to medical students, specialist doctors, and researchers whose work will be affected by artificial intelligence.

This book discusses all aspects infectious CNS pathology, including different bacterial, viral, fungal, mycoplasma and protozoan pathogens, accompanied by illustrations that show macro- and histopathological changes. It also presents microbiological, epidemiological and clinical data, with a particular focus on meningitis and encephalitis of different bacterial and viral aetiologies, influenza, COVID-19 and other viral and bacterial generalized infections. Further, the book explores the importance of mixed infections, including those in the late stages of HIV infection, as well as pathological changes in different age groups including newborns. A special chapter is devoted to the probable role of biological pathogens in noninfectious brain pathology.