3 results
Search Results
2. CannibiSenS: an on-demand rapid screen for THC in human saliva.
- Author
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Churcher, Nathan Kodjo Mintah, Dhamu, Vikram Narayanan, and Prasad, Shalini
- Subjects
SALIVA ,CANNABIDIOL ,SURFACE plasmon resonance ,SUBSTANCE abuse - Abstract
Management of substances that possess high potential for abuse requires a comprehensive understanding of the temporal effects of a corresponding volume of intake. Cannabis is deemed as one of the most widely used drugs in the United States and studies related to the primary psychoactive compound present in it, Δ-9-tetrahydrocannabinol (THC), have revealed that it causes adverse health effects. In this study, we present a field-deployable electrochemical sensing system that can detect THC at the 5 ng mL
−1 cut-off level with a dynamic range of 0.1–100 ng mL−1 in human saliva. Considering the complexity of the human saliva matrix, the specificity study demonstrated selectivity towards THC with minimum interactions with ethanol and cannabidiol (CBD). Surface Plasmon Resonance (SPR) has been implemented to visualize and validate the capture probe as a means for THC detection. A robust, compatible binary classifier model has been shown in this work to effectively group samples into THC+ (high) and THC− (low) groups from human saliva with an accuracy greater than 90% considering a limited dataset. Hence, we demonstrate the potential of an innovative end-to-end system to effectively regulate cannabis use and prevent substance abuse in our surroundings. [ABSTRACT FROM AUTHOR]- Published
- 2023
- Full Text
- View/download PDF
3. Conversion of plastic waste into high-value lubricants: techno-economic analysis and life cycle assessment.
- Author
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Cappello, Vincenzo, Sun, Pingping, Zang, Guiyan, Kumar, Shishir, Hackler, Ryan, Delgado, Hernan E., Elgowainy, Amgad, Delferro, Massimiliano, and Krause, Theodore
- Subjects
PRODUCT life cycle assessment ,PLASTIC scrap ,HIGH density polyethylene ,CIRCULAR economy ,MONETARY incentives ,PLASTIC recycling ,LUBRICATION & lubricants - Abstract
Given the low recycling rate of plastic waste in the United States due to low economic incentives, it is of great interest to develop a technology to upgrade plastic waste with favorable economics. Plastic upcycling to valuable chemicals could ensure a circular economy for plastics and reduce the environmental burden caused by their end use cycle and disposal. A conceptual facility to convert 250 metric ton (MT) per day of plastic waste was modeled; the main product was a high-quality liquid (HQL) with a similar performance to polyalphaolefin (PAO) lubricants. The modeled process had a lubricant yield of up to 90% based on the experimental results at the laboratory scale. Techno-economic analysis (TEA) and life cycle assessment (LCA) were also performed to evaluate the process economics and its environmental impact. By using a mixture of colored and natural high-density polyethylene (HDPE), the production cost was in the range of $0.6–$1.98 per kg of lubricant, depending on the operating conditions. The life cycle emissions were in the range of 0.48–1.2 kg
CO kg2e Lub −1 showing, for the best case scenario, a 52% reduction relative to the emissions for petroleum lubricants, and a 74% reduction relative to the emissions for PAO lubricants. The impacts of the lubricant yield, the catalyst amount, and reaction time were evaluated, and their effect on the final production cost was discussed. [ABSTRACT FROM AUTHOR]- Published
- 2022
- Full Text
- View/download PDF
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