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Chondrus ocellatus is a kind of red algae and shows diverse pharmacological activities. This article planned to extract polyphenols and study their pharmacological activities. The extraction conditions were optimized utilizing response surface methodology. Antioxidant activities, α‐amylase, and α‐glucosidase inhibitory activity were tested. The consequences revealed that optimal extraction was obtained with an ethanol concentration of 61%, an extraction time of 41 min, and an extraction temperature of 60°C. The extracts inhibited ABTS and DPPH with 43.48%–53.50% and 13.11%–25.77%, respectively. For H2O2, the inhibition was 18.4–85.6 U/ml. The IC50 values were 16.92 ± 2.31 mg/ml (anti‐α‐glycosidase) and 375.3 ± 3.47 mg/ml (anti‐α‐glucosidase). The extracts showed competitive and mixed inhibition against α‐amylase and α‐glucosidase, respectively. This study provided preliminary data for the anti‐type 2 diabetes treatment of phenolic compounds from C. ocellatus. Practical applications: The algae were not only a marine plants but also a medicine. This study demonstrated that polyphenol extract of the alga Chondrus ocellatus is a potential drug for the treatment of type 2 diabetes. Further study is necessary to evaluate the effect of polyphenol extracts in animal models and establish their beneficial activity in humans. [ABSTRACT FROM AUTHOR]

The relation between electroencephalogram signals, thermal comfort, and cognitive performance in neutral to hot indoor environment was investigated. The experiments were carried out at four temperatures: 26ºC, 30ºC, 33ºC, and 37ºC, and two relative humidity levels: 50% and 70%. Thirty‐two subjects were exposed for 175 min. The electroencephalogram signals were measured for 30 min 25 min after the onset of exposure while the recruited subjects performed neurobehavioral tests and rated their thermal comfort. The relative power of electroencephalogram signals has a significant correlation with thermal comfort and performance of neurobehavioral tests. The ratings of acceptability of thermal environment and thermal comfort, the speed, accuracy, and PI of completing the tests are negatively correlated with the relative power of δ‐band, but positively correlated with θ‐band, α‐band, and β‐band. The ratings of thermal sensation have a better correlation with the above four bands, but the correlation trend is opposite. A linear relation was found between electroencephalogram signals and the speed. The results showed that the relative power of P7 channel located in the occipital lobe is the most suitable as a single electroencephalogram channel to reflect joint thermal comfort and cognitive performance at high temperatures, especially its α‐band. [ABSTRACT FROM AUTHOR]