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Your search keyword '"Takahashi, M."' showing total 12 results
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12 results on '"Takahashi, M."'

1. P125 Neoadjuvant pembrolizumab + chemotherapy vs placebo + chemotherapy followed by adjuvant pembrolizumab vs placebo for early TNBC: surgical outcomes from the phase 3 KEYNOTE-522 study.

Author

Kümmel, S., Schmid, P., Harbeck, N., Takahashi, M., Untch, M., Boileau, J.-F., Cortes, J., McArthur, H., Dent, R., O'Shaughnessy, J., Pusztai, L., Foukakis, T., Park, Y.H., Hui, R., Cardoso, F., Denkert, C., Zhu, Y., Pan, W., Karantza, V., and Fasching, P.

Subjects
PEMBROLIZUMAB, PLACEBOS, CANCER chemotherapy
Published
2023
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4. VP7-2021: KEYNOTE-522: Phase III study of neoadjuvant pembrolizumab + chemotherapy vs. placebo + chemotherapy, followed by adjuvant pembrolizumab vs. placebo for early-stage TNBC.

Author

Schmid, P., Cortes, J., Dent, R., Pusztai, L., McArthur, H., Kümmel, S., Bergh, J., Denkert, C., Park, Y.H., Hui, R., Harbeck, N., Takahashi, M., Untch, M., Fasching, P.A., Cardoso, F., Ding, Y., Tryfonidis, K., Aktan, G., Karantza, V., and O'Shaughnessy, J.

Subjects
*ADJUVANT treatment of cancer, *TRIPLE-negative breast cancer, *PEMBROLIZUMAB, *CANCER chemotherapy, *PLACEBOS, *CANCER treatment
Published
2021
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5. 135MO HRQoL with neoadjuvant pembrolizumab + chemotherapy vs placebo + chemotherapy, followed by adjuvant pembrolizumab vs placebo for early-stage TNBC: Results from KEYNOTE-522.

Author

Dent, R.A., Cortés, J., Pusztai, L., McArthur, H.L., Kuemmel, S., Bergh, J., Denkert, C., Park, Y.H., Hui, R., Harbeck, N., Takahashi, M., Untch, M., Fasching, P.A., Cardoso, F., Haiderali, A., Jia, L., Nguyen, A.M., Pan, W., O'Shaughnessy, J., and Schmid, P.

Subjects
*PEMBROLIZUMAB, *PLACEBOS, *CANCER chemotherapy, *QUALITY of life
Published
2022
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6. The void fraction and frictional pressure drop of upward two-phase flow under high pressure brine condition.

Author

Shibata, N., Miwa, S., Sawa, K., Moriya, H., Takahashi, M., Murayama, T., and Tenma, N.

Subjects
*TWO-phase flow, *PRESSURE drop (Fluid dynamics), *POROSITY, *TRANSITION flow, *METHANE hydrates, *SALT
Abstract

• Extensive literature survey on two-phase flow experiment using 12 m or longer vertical tube was conducted. • Experiments were conducted on two-phase flow regime observation, void fraction and frictional pressure drop measurement over a long channel length under high-pressure brine conditions. • The transition of flow regime took place at higher superficial gas velocity under brine conditions. • Through drift-flux model analysis, change in gas velocity under brine conditions was confirmed. • New frictional pressure drop model at high-pressure two-phase flow under brine conditions is proposed. The offshore methane hydrate production test conducted in Japan has demonstrated a successful production of methane gas from marine gas hydrates using depressurization methods. The method produces methane gas by dissociating methane hydrate, which is stable at low temperature and high pressure conditions, by lowering the bottom-hole pressure in the wellbore. Under this method, stable control of bottom-hole pressure is necessary to ensure continuous methane gas production. Therefore, understanding the behavior of upward gas–liquid two-phase flow, involving gas-brine mixture, in a wellbore is essential for the proper pressure drop evaluation in the production line. In the present study, void fraction and frictional pressure drop behaviors under nitrogen-brine two-phase flow conditions is investigated using the high-pressure test facility of 52.7 mm inner diameter and 28 m height. The measured void fraction was assessed using drift-flux model, and the results showed that the decrease in bubble diameter under bubbly flow in gas-brine two-phase flow conditions resulted in decrease in bubble rise velocity and uniformity of bubble distribution. It was also found that, under bubbly flow in gas-brine mixture, the frictional pressure drop tends to further decrease with elevation. Based on these findings and obtained experimental dataset, the new frictional pressure model for gas-brine two-phase flow under high-pressure conditions is developed in the present study. [ABSTRACT FROM AUTHOR]

Published
2023
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7. 1224P Final analysis of clinical outcomes in the DELIVER trial: Observational study of nivolumab treatment in advanced gastric cancer (JACCRO GC-08).

Author

Sunakawa, Y., Inoue, E., Sakamoto, Y., Kawabata, R., Ishiguro, A., Akamaru, Y., Kito, Y., Takahashi, M., Matsuyama, J., Yabusaki, H., Makiyama, A., Suzuki, T., Tsuda, M., Yasui, H., Kawakami, H., Nakajima, T.E., Muro, K., Matoba, R., Ichikawa, W., and Fujii, M.

Subjects
*STOMACH cancer, *TREATMENT effectiveness, *NIVOLUMAB, *SCIENTIFIC observation, *THERAPEUTICS
Published
2022
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8. 256P Difference of immunological status and response to immune checkpoint inhibitor between recurrent and de novo stage IV HER2-negative breast cancer in NEWBEAT trial (WJOG9917BTR).

Author

Ozaki, Y., Kitano, S., Yamashita, M., Ikarashi, D., Tsurutani, J., Iwasa, T., Takahashi, M., Mukohara, T., Masuda, N., Futamura, M., Minami, H., Matsumoto, K., Tanabe Hashimoto, Y., Kawabata, H., Yoshimura, K., and Takano, T.

Subjects
*IMMUNE checkpoint inhibitors, *IMMUNITY, *IMMUNE response, *IPILIMUMAB
Published
2022
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9. 1776P Immune microenvironment, homologous recombination deficiency and therapeutic response to neoadjuvant chemotherapy in triple-negative breast cancer: JBCRG22 TR.

Author

Ueno, T., Kitano, S., Masuda, N., Ikarashi, D., Yamashita, M., Kadoya, T., Bando, H., Yamanaka, T., Ohtani, S., Nagai, S., Nakayama, T., Takahashi, M., Saji, S., Aogi, K., Velaga, R.M., Kawaguchi, K., Morita, S., Haga, H., Ohno, S., and Toi, M.

Subjects
*CANCER chemotherapy, *TRIPLE-negative breast cancer, *NEOADJUVANT chemotherapy
Published
2021
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10. P-56 A multicenter prospective translational study using circulating tumor DNA to identify acquired genomic alterations in recurrent gastric or gastroesophageal junction adenocarcinoma in patients who received curative-intent treatment (Liquid-GEAR).

Author

Takeda, H., Suzuki, T., Okita, A., Ishiguro, A., Yabusaki, H., Matsuyama, J., Takahashi, M., Takegawa, N., Fukushima, N., Nishina, S., Kawabata, R., Kito, Y., Negoro, Y., and Sunakawa, Y.

Subjects
*CIRCULATING tumor DNA, *ESOPHAGOGASTRIC junction
Published
2021
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12. 277P Phase II randomized study of trimebutine maleate and probiotics for abemaciclib-induced diarrhea in patients with HR-positive and HER2-negative advanced breast cancer (MERMAID) WJOG11318B.

Author

Masuda, H., Tanabe, Y., Matsumoto, K., Shimomura, A., Doi, M., Miyoshi, Y., Takahashi, M., Sagara, Y., Tokunaga, S., Iwasa, T., Niikura, N., Yoshimura, K., Takano, T., and Tsurutani, J.

Subjects
*BREAST cancer, *MALEIC acid, *PROBIOTICS, *MERMAIDS, *DIARRHEA, *TUMOR classification
Published
2021
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