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This article focuses on the western cult of two saints, Cyrus and John, which was founded in Egypt – where Sophronios of Jerusalem composed the anargyroi 's hagiographic dossier in the seventh century – and quickly spread to Italy. The analysis of the manuscripts containing the Latin translations of Sophronios's texts allows us to trace the diffusion of this hagiographic corpus in Rome, and to link its transfer and first reception in Italy to a broad Mediterranean migration. [ABSTRACT FROM AUTHOR]