27 results on '"wipe"'
Search Results
2. Contact Dermatitis to Isothiazolinone Preservatives
- Author
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Latheef, Faheem and Wilkinson, Stephen Mark
- Published
- 2023
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3. A Wipe-Based Stool Collection and Preservation Kit for Microbiome Community Profiling.
- Author
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Hua, Hui, Meydan, Cem, Afshin, Evan E., Lili, Loukia N., D'Adamo, Christopher R., Rickard, Nate, Dudley, Joel T., Price, Nathan D., Zhang, Bodi, and Mason, Christopher E.
- Subjects
ETHYLENEDIAMINETETRAACETIC acid ,DIMETHYL sulfoxide ,SPECIES diversity ,SALT ,COLLECTIONS - Abstract
While a range of methods for stool collection exist, many require complicated, self-directed protocols and stool transfer. In this study, we introduce and validate a novel, wipe-based approach to fecal sample collection and stabilization for metagenomics analysis. A total of 72 samples were collected across four different preservation types: freezing at -20°C, room temperature storage, a commercial DNA preservation kit, and a dissolvable wipe used with DESS (dimethyl sulfoxide, ethylenediaminetetraacetic acid, sodium chloride) solution. These samples were sequenced and analyzed for taxonomic abundance metrics, bacterial metabolic pathway classification, and diversity analysis. Overall, the DESS wipe results validated the use of a wipe-based capture method to collect stool samples for microbiome analysis, showing an R
2 of 0.96 for species across all kingdoms, as well as exhibiting a maintenance of Shannon diversity (3.1-3.3) and species richness (151-159) compared to frozen samples. Moreover, DESS showed comparable performance to the commercially available preservation kit (R2 of 0.98), and samples consistently clustered by subject across each method. These data support that the DESS wipe method can be used for stable, room temperature collection and transport of human stool specimens. [ABSTRACT FROM AUTHOR]- Published
- 2022
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4. A Wipe-Based Stool Collection and Preservation Kit for Microbiome Community Profiling
- Author
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Hui Hua, Cem Meydan, Evan E. Afshin, Loukia N. Lili, Christopher R. D’Adamo, Nate Rickard, Joel T. Dudley, Nathan D. Price, Bodi Zhang, and Christopher E. Mason
- Subjects
microbiome ,wipe ,metagenomics ,DESS ,stool collection ,Immunologic diseases. Allergy ,RC581-607 - Abstract
While a range of methods for stool collection exist, many require complicated, self-directed protocols and stool transfer. In this study, we introduce and validate a novel, wipe-based approach to fecal sample collection and stabilization for metagenomics analysis. A total of 72 samples were collected across four different preservation types: freezing at -20°C, room temperature storage, a commercial DNA preservation kit, and a dissolvable wipe used with DESS (dimethyl sulfoxide, ethylenediaminetetraacetic acid, sodium chloride) solution. These samples were sequenced and analyzed for taxonomic abundance metrics, bacterial metabolic pathway classification, and diversity analysis. Overall, the DESS wipe results validated the use of a wipe-based capture method to collect stool samples for microbiome analysis, showing an R2 of 0.96 for species across all kingdoms, as well as exhibiting a maintenance of Shannon diversity (3.1-3.3) and species richness (151-159) compared to frozen samples. Moreover, DESS showed comparable performance to the commercially available preservation kit (R2 of 0.98), and samples consistently clustered by subject across each method. These data support that the DESS wipe method can be used for stable, room temperature collection and transport of human stool specimens.
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- 2022
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5. Mechanical Wiping Increases the Efficacy of Liquid Disinfectants on SARS-CoV-2.
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Sloan, Angela, Kasloff, Samantha B., and Cutts, Todd
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SARS-CoV-2 ,DISINFECTION & disinfectants ,BIOCIDES ,VIRUS inactivation ,CHLORINE dioxide ,STAINLESS steel ,SURFACE cleaning - Abstract
High-touch environmental surfaces are acknowledged as potential sources of pathogen transmission, particularly in health care settings where infectious agents may be readily abundant. Methods of disinfecting these surfaces often include direct application of a chemical disinfectant or simply wiping the surface with a disinfectant pre-soaked wipe (DPW). In this study, we examine the ability of four disinfectants, ethanol (EtOH), sodium hypochlorite (NaOCl), chlorine dioxide (ClO
2 ), and potassium monopersulfate (KMPS), to inactivate SARS-CoV-2 on a hard, non-porous surface, assessing the effects of concentration and contact time. The efficacy of DPWs to decontaminate carriers spiked with SARS-CoV-2, as well as the transferability of the virus from used DPWs to clean surfaces, is also assessed. Stainless steel carriers inoculated with approximately 6 logs of SARS-CoV-2 prepared in a soil load were disinfected within 5 min through exposure to 66.5% EtOH, 0.5% NaOCl, and 1% KMPS. The addition of mechanical wiping using DPWs impregnated with these biocides rendered the virus inactive almost immediately, with no viral transfer from the used DPW to adjacent surfaces. Carriers treated with 100 ppm of ClO2 showed a significant amount of viable virus remaining after 10 min of biocide exposure, while the virus was only completely inactivated after 10 min of treatment with 500 ppm of ClO2 . Wiping SARS-CoV-2-spiked carriers with DPWs containing either concentration of ClO2 for 5 s left significant amounts of viable virus on the carriers. Furthermore, higher titers of infectious virus retained on the ClO2 -infused DPWs were transferred to uninoculated carriers immediately after wiping. Overall, 66.5% EtOH, 0.5% NaOCl, and 1% KMPS appear to be highly effective biocidal agents against SARS-CoV-2, while ClO2 formulations are much less efficacious. [ABSTRACT FROM AUTHOR]- Published
- 2022
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6. Baby wipes and nappy rash – what is the relationship? A review.
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Mactaggart, Emma, Orchard, David, and Mui Tam, Mei
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NONWOVEN fabric wipes , *BETAINE , *ALLERGENS , *LITERATURE reviews , *LINALOOL - Abstract
Baby wipes are a commonly used cleansing method for infants. A literature review has been performed to assess if using baby wipes is beneficial or harmful compared to water and cloth in terms of nappy rash. This includes a detailed analysis of baby wipe ingredients, as many skin irritants as well as allergens are identified. MedLine, Embase and PubMed were searched and after 420 titles and abstracts were screened, 21 studies remained for inclusion. Baby wipes are deemed as superior to water and cloth in the majority of the literature. However, no definitive conclusion can be drawn as many studies are also industry funded. The most notable allergens identified are fragrances, such as linalool, cocamidopropyl betaine (surfactant), formaldehyde‐releasing preservatives and other preservatives, including methylisothiazolinone and methylchloroisothiazolinone. As not all allergens are listed on the label accurately, this can be misleading for the consumer. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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7. Polybrominated diphenyl ether (PBDE) concentrations and resulting exposure in homes in California: relationships among passive air, surface wipe and dust concentrations, and temporal variability.
- Author
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Bennett, DH, Moran, RE, Wu, X May, Tulve, NS, Clifton, MS, Colón, M, Weathers, W, Sjödin, A, Jones, R, and Hertz-Picciotto, I
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Humans ,Dust ,Flame Retardants ,Housing ,Air Pollution ,Indoor ,Environmental Exposure ,Environmental Monitoring ,Age Factors ,Time Factors ,Floors and Floorcoverings ,Adult ,Aged ,Middle Aged ,Child ,Child ,Preschool ,California ,Halogenated Diphenyl Ethers ,Air concentration ,Polybrominated diphenyl ethers ,Residential environment ,Temporal variability ,Wipe ,Health Effects of Indoor Air Pollution ,Earth Sciences ,Engineering ,Medical and Health Sciences ,Building & Construction - Abstract
Polybrominated diphenyl ethers (PBDEs) are used as flame retardants in furniture foam, electronics, and other home furnishings. A field study was conducted that enrolled 139 households from California, which has had more stringent flame retardant requirements than other countries and areas. The study collected passive air, floor and indoor window surface wipes, and dust samples (investigator collected using an HVS3 and vacuum cleaner) in each home. PentaBDE and BDE209 were detected in the majority of the dust samples and many floor wipe samples, but the detection in air and window wipe samples was relatively low. Concentrations of each PBDE congener in different indoor environmental media were moderately correlated, with correlation coefficients ranging between 0.42 and 0.68. Correlation coefficients with blood levels were up to 0.65 and varied between environmental media and age group. Both investigator-collected dust and floor wipes were correlated with serum levels for a wide range of congeners. These two sample types also had a relatively high fraction of samples with adequate mass for reliable quantification. In 42 homes, PBDE levels measured in the same environmental media in the same home 1 year apart were statistically correlated (correlation coefficients: 0.57-0.90), with the exception of BDE209 which was not well correlated longitudinally.
- Published
- 2015
8. An in vitro comparison of standard cleaning to a continuous passive disinfection cap for the decontamination of needle-free connectors
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Anna L. Casey, Tarja J. Karpanen, Peter Nightingale, and Tom S. J. Elliott
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Disinfection cap ,Wipe ,Needle-free connectors ,Isopropyl alcohol ,Chlorhexidine ,Infectious and parasitic diseases ,RC109-216 - Abstract
Abstract Background The optimal decontamination method for needle-free connectors is still unresolved. The objective of this study was to determine if a continuous passive disinfection cap is as effective as standard cleaning for the microbial decontamination of injection ports of two types of needle-free connectors. Methods The injection ports of needle-free connectors were inoculated with Staphylococcus aureus and allowed to dry. Disinfection caps containing 70% (v/v) isopropyl alcohol (IPA) were attached to the connectors for one, three or 7 days and were compared with needle-free connectors cleaned with 2% (w/v) chlorhexidine gluconate (CHG) in 70% (v/v) IPA. The number of S. aureus remaining on the injection ports was evaluated. Median log10 reductions and 95% confidence interval (CI) were calculated and data analyzed using the Mann-Whitney test. Results The application of the disinfection cap resulted in a significantly higher reduction in S. aureus than the 2% (w/v) CHG in 70% (v/v) IPA wipe, achieving a > 5 Log10 reduction in CFU at each time point. Conclusions The disinfection caps resulted in a significantly higher reduction in S.aureus on the injection ports when compared to the use of a 2% (w/v) CHG in 70% (v/v) IPA wipe. This offers an explanation for the lower rates of central-line associated bloodstream infection (CLABSI) associated with the use of disinfection caps reported in clinical studies.
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- 2018
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9. Transport of non-flushable wipes in sewers and its application in sewer management.
- Author
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Peng, Xinzai, Zhu, David Z., and Zhang, Wenming
- Subjects
- *
SEWERAGE , *FLOW velocity , *COVID-19 pandemic , *FROUDE number , *SPECIFIC gravity , *SHEAR flow - Abstract
Flushing wipes into sewers has caused severe blockage issues in urban sewer systems, especially during the COVID-19 pandemic; however, the transport mechanism of wipes in sewers has not been reported. To address this knowledge gap, the transport of non-flushable wipes with different densities was systematically studied in a circular pipe. The critical shear stress and flow velocity for the incipient motion of wipes were found to increase with increasing wipe density and with decreasing relative wipe size, starting from 0.02 Pa and 0.05 m/s, respectively. Non-dimensional equations were developed for characterizing the incipient motion using two parameters: the critical Shield number and particle Froude number. The mean wipe velocity, mean ambient flow velocity, and wipe density could be well described by a power relationship. The ratio of wipe velocity to local flow velocity increased with the increase of wipe vertical position in the pipe. Different movement modes of wipes were observed and classified by using the ambient cross-sectional average velocity U a : the sliding mode started first, followed by rolling/saltation at U a = 0.18 m/s and suspension at U a = 0.41 m/s. The threshold values for each mode were found to increase with increasing wipe density. Finally, the research results were applied in sewer management. [Display omitted] • Wipe incipient motion depends on critical Shield number & particle Froude number. • The relationship between wipe velocity and ambient flow velocity was established. • Different transport modes of wipes were classified using ambient flow velocity. • Transport mechanism of wipes can be applied in effective sewer solid management. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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10. WPŁYW SPOSOBU ŁĄCZENIA UJĘĆ NA ATRAKCYJNOŚĆ REKLAMY AUDIOWIZUALNEJ (NA PODSTAWIE BADAŃ ANKIETOWYCH).
- Author
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Barczyk-Sitkowska, Agnieszka
- Abstract
Copyright of Media Research / Zeszyty Prasoznawcze is the property of Jagiellonian University Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
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11. Evaluation of bacterial presence on lead X-ray aprons utilised in the operating room via IBIS and standard culture methods.
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Jain, Sameer, Rajfer, Rebecca A, Melton-Kreft, Rachel, Nistico, Laura, Miller, Mark C, Stoodley, Paul, Altman, Daniel T, and Altman, Gregory T
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- *
BIOFILMS , *CHI-squared test , *MASS spectrometry , *PROTECTIVE clothing , *MICROBIAL sensitivity tests , *MICROSCOPY , *NEISSERIA , *OPERATING rooms , *POLYMERASE chain reaction , *PROPIONIBACTERIUM , *PSEUDOMONAS , *STATISTICAL sampling , *STAPHYLOCOCCUS aureus , *STERILIZATION (Disinfection) , *STREPTOCOCCUS , *X-rays , *FLUORESCENCE in situ hybridization , *BACTERIAL contamination - Abstract
Background: Despite precautions, surgical procedures carry risk of infection. Radiation-protective lead aprons worn by operating personnel are a potential source of bacterial contamination and have not been fully evaluated. Aim/objective: To evaluate lead aprons as a source of bacterial contamination, identify organisms most commonly found on this source, and devise a method with which to lower the risk of contamination. Methods: In this basic science study, 20 randomly selected lead X-ray aprons were swabbed at three time points. The experimental treatment was with a hospital-grade disinfectant wipe. The samples were assessed for bacterial growth via traditional plating methods and mass spectrometry. Plates were graded on a scale of 0 to 4+ based on the number of quadrants with growth. Growth on one quadrant or more was considered contaminated. Findings/results: Bacteria were initially detected via IBIS on a majority of the aprons (32/40), most commonly Staphylococcus epidermidis and Propionibacterium acnes. Virulent organisms cultured were Methicillin-resistant Staphylococcus epidermidis (MRSE), Neisseria, Streptococcus viridans and pseudomonas. MRSE were detected on 5/20 of the samples. Immediately after treatment, the majority of aprons showed less bacterial contamination (0/20 standard culture positive; 13/20 IBIS positive) with some recurrence at the 6-h time point (2/20 standard culture positive, 16/20 IBIS positive). All MRSE detected initially was eradicated. Discussion: Lead X-ray aprons worn in the operating room harbour bacteria. Disinfecting before use may prevent the introduction of virulent organisms to patients. Our proposed method of sanitising with a disinfectant wipe is quick and effective. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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12. Employ of magnetic polyaniline coated chitosan nanocomposite for extraction and determination of phthalate esters in diapers and wipes using gas chromatography.
- Author
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Razavi, Nourolhoda and Es'haghi, Zarrin
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PHTHALATE esters , *POLYANILINES , *GAS chromatography , *PEARSON correlation (Statistics) , *STANDARD deviations - Abstract
In the present study, an efficient method for the simultaneous extraction and determination of four types of trace phthalate esters (PAEs) in diapers and wipes samples using magnetic chitosan coated with polyaniline (Fe 3 O 4 @CHI@PANI) solid-phase extraction coupled with gas chromatography equipped with a flame ionization detector (GC–FID) was developed. For this purpose, magnetic chitosan coated with polyaniline (Fe 3 O 4 @CHI@PANI) synthesized, characterized by FT-IR, FESEM, TEM, VSM, TGA and used as a sorbent in extraction procedure. At first, the effective parameters such as the amount of sorbent, extraction solvent, time of extraction and desorption, aqueous solution pH, and salt addition were optimized. Following extraction for the adsorbent, under optimum extraction conditions, the analytes were quantified by GC-FID. Acceptable linearity ranges 0.001–2 μgmL −1 with correlation coefficients (R 2 ) larger than 0.9886 was achieved for all four phthalate esters. Limits of detection (LOD) ranged from 0.0002 to 0.0005 μgmL −1 and precision of the method, expressed as the relative standard deviation (RSD%, n = 3), was checked at three levels obtaining good results (1.41–3.94%). Finally, the applicability of the method successfully investigated for phthalates in the diaper and wipe samples. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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13. Video Shot Boundary Detection Using Dual Tree and Double Density Dual Tree Complex Wavelet Transform: A Comparison
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Mishra, Ravi and Singhai, S. K
- Published
- 2015
14. Volatile Organic Compounds in Disposable Diapers and Baby Wipes in the US: A Survey of Products and Health Risks.
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Lin N, Ding N, Meza-Wilson E, Devasurendra AM, Godwin C, Park SK, and Batterman S
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- Adult, Infant, Child, Aged, Humans, Child, Preschool, Alkanes, Benzene, Carcinogens, Dioctyl Sulfosuccinic Acid, Volatile Organic Compounds
- Abstract
Many thousands of diapers are worn by young children and the elderly, who have thin and sensitive skin that is highly vulnerable to chemicals, including volatile organic compounds (VOCs) that may be ingredients of these products or present as inadvertent or residual components. The levels and potential health risks of VOCs in diapers have not been reported previously. In this study, we collected 31 disposable hygiene products in the US market based on market share and analyzed 98 target VOCs using purge and trap sampling and thermal desorption/gas chromatography/mass spectrometer analysis. Exposures and risks were modeled using reasonable upper level exposure scenarios. Adult diapers contained the highest total target VOC concentration (median level of 23.5 μg/g), and the predominant VOCs were alkanes. In some diapers, the estimated noncancer risk from these VOCs was sometimes very large (hazard quotient of 1609) due to n -heptane. Baby diapers contained several known or suspected carcinogens, including benzene and 1,4-dioxane, and the lifetime cancer risk from some diapers approached 1 per million under a worst-case scenario. Store-brand products had higher levels of VOCs than generic brands, and products labeled "organic" or "for sensitive skin" did not necessarily have lower levels. Our results show that toxic VOCs were found in all tested disposable diapers and wipes at trace levels, and risks from using some diapers in high use exposure scenarios are high enough to warrant additional attention and possibly corrective measures. We recommend eliminating and monitoring toxic ingredients and disclosing all chemicals that may be in these products.
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- 2023
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15. Research of the selection of a gelling agent with further saturation of wipes with active prolonged effect
- Author
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Buhai, A. V. and Semchenko, K. V.
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apple pectin ,xanthan gum ,carbopol ,technology ,aristoflex ,wipe ,carbomer 940 ,gelling agent - Abstract
Introduction. During our research of the selection of gelling agents followed by saturation of wipes with an active prolonged effect, many factors should be considered. This fact may influence further drug development. The most important characteristics include the physical and chemical properties of studied gelling agents, the technological characteristics of these gelling agents, the quality of gels they form, their stability and safety, the possibility of choosing a gelling agent with an active pharmaceutical ingredient without any incompatibility. Also, one of the most important characteristics of studied gelling agents is their ability to form stable and homogeneous disperse systems, that should be easy to dissolve and make it possible to create series of gels with various viscosities. The aim of our work is to substantiate the selection of gelling agent for further saturation of wipes with an active prolonged effect. Materials and methods. As the objects of research were gelling agents, as well as the resulting samples of wipes that were based on them. For a more objective analysis, gelling agents were chosen by natural and synthetic origin. There were researched such gelling agents as apple pectin (natural origin), aristoflex (synthetic origin), xanthan gum (natural origin), carbopol (synthetic origin) and carbomer 940 (synthetic origin). Results and discussion. For the immobilization and fixation of gels when creating a wipe, the adsorption method, which is the easiest to perform and the most economically beneficial and essentially represents the saturation of the carrier with a saturating solution, was chosen. Based on the biblio-semantic, physico-chemical and technological studies, a laboratory technology of material saturation was developed – a carrier that allows for maximum fixation of gelling agents on a wipe – the first saturation by immersion for 20 minutes, followed by wringing and drying, repeated saturation for 15 and 10 minutes with subsequent wringing and drying at temperature 75±5 ºС. 15 series of wipes samples based on selected gelling agents were investigated. The concentration of each gelling agent was established based on well-known technological recommendations and previously conducted scientific studies: apple pectin – 5.0 %, aristoflex – 0.5 %, xanthan gum – 1.0 %, carbopol – 0.5 %, carbomer 940 – 0,5 %. The mass of the wipe without saturation is 0.17 g. The saturation followed by drying was carried out in 3 stages. The obtained results indicate the following: Apple pectin: 5 minutes after the start of the experiment, saturation of the wipe with the gel almost does not occur, since subsequent saturations with a probability of 95 % fall into the confidence interval of the five-minute experiment [2,24;2,50]. The average percentage of drying is 52.79 %, which indicates an unsatisfactory result. Aristoflex: the maximum saturation of the wipe material with the gel occurs after 15 minutes, which with a probability of 95 % falls into the confidence interval [2.48; 3.02], and the calculated coefficients of variation confirm the correctness of the conducted experiment. The average percentage of drying is 29.75 %, which indicates an unsatisfactory result. Xanthan gum: the maximum saturation of the wipe material with the gel occurs after 15 minutes, which with a probability of 95 % falls into the confidence interval [2.45; 2.63], and the calculated coefficients of variation also confirm the correctness of the conducted experiment. The average percentage of drying is 35.65 %, which indicates an unsatisfactory result. Carbopol: the maximum saturation of the wipe material with the gel occurs after 15 minutes, which with a probability of 95 % falls into the confidence interval [2.45; 2.63], and the calculated coefficients of variation also confirm the correctness of the conducted experiment. The average percentage of drying is 20.21 %, which indicates a satisfactory result and the advisability of using carbopol to saturate wipes. Carbomer 940: the maximum saturation of the wipe material with gel occurs after 10 min, which with a probability of 95 % falls into the confidence interval [1.54; 2.29], and the calculated coefficients of variation also confirm the correctness of the conducted experiment. The average percentage of drying is 39.48 %, which indicates an unsatisfactory result. , it was found that the best organoleptic and technological characteristics among the presented samples were given by gelling agent of synthetic origin carbopol. It was experimentally found that this gelling agent has a low percentage of drying, as well as a high saturation coefficient compared to other gelling agents, presented in the samples. The additional statistical analysis showed that carbopol had many advantages in comparison with the other gelling agents. Conclusions. Based on the results obtained, carbopol is substantiated as the most prospect gelling agent for the further saturation of the wipes with an active prolonged effect. It has been experimentally proven that this gelling agent has all the necessary technological characteristics for the further development of a new drug based on carbopol., {"references":["1.\tKhokhlenkova NV. Development of methodical approaches to the creation of pharmacologically active dressings // Zaporizhzhya Medical Journal. 2012. Vol. 5. P. 105-109.","2.\tDulong, C., Brett, K., & Argáez, C.. Skin Preparation for Injections: A Review of Clinical Effectiveness, Cost-Effectiveness and Guidelines. 2020. Canadian Agency for Drugs and Technologies in Health.","3.\t Naumann, B. D., Arnold, S. F. Setting surface wipe limits for skin sensitizers // Toxicology and industrial health. 2019. Vol. 35(9). P. 614–625. https://doi.org/10.1177/0748233719875365","4.\tKaegi, M., Adlhart, C., Lehmann, M., Risch, M., Wessling, W., Klaffenbach, P. A Novel Microfiber Wipe for Delivery of Active Substances to Human Skin: Clinical Proof of Concept. // Polymers. 2020. Vol. 12(11). P. 2715. https://doi.org/10.3390/polym12112715","5.\tHariyadi, D. M., Isnaeni, I., Sudarma, S., Suciati, S., Rosita, N. Peel-off emulgel mask of Cocos nucifera L. Extract using gelling agent carbomer 940 as antiacne against Propionibacterium acnes ATCC 11827 // Journal of advanced pharmaceutical technology & research. 2020. Vol. 11(4). P. 220–225. https://doi.org/10.4103/japtr.JAPTR_51_20","6.\tDouglas, T., Dziadek, M., Schietse, J., Boone, M., Declercq, H. A., Coenye, T., Vanhoorne, V., Vervaet, C., Balcaen, L., Buchweitz, M., Vanhaecke, F., Van Assche, F., Cholewa-Kowalska, K., Skirtach, A. G. Pectin-bioactive glass self-gelling, injectable composites with high antibacterial activity. // Carbohydrate polymers. 2019. Vol. 205. P. 427–436. https://doi.org/10.1016/j.carbpol.2018.10.061","7.\tGiri, T. K., Choudhary, C., Alexander, A., Ajazuddin, Badwaik, H., Tripathy, M., Tripathi, D. K. Sustained Release of Diltiazem Hydrochloride from Cross-linked Biodegradable IPN Hydrogel Beads of Pectin and Modified Xanthan Gum // Indian journal of pharmaceutical sciences. 2013. Vol. 75(6). P. 619–627.","8.\tAlgin Yapar, E., Tuncay Tanriverdi, S., Aybar Tural, G., Gümüş, Z. P., Turunç, E., Gokce, E. H. An examination of carbopol hydrogel/organogel bigels of thymoquinone prepared by microwave irradiation method // Drug development and industrial pharmacy. 2020. Vol. 46(10). P. 1639–1646. https://doi.org/10.1080/03639045.2020.1820031","9.\tLaffleur F. Evaluation of chemical modified hydrogel formulation for topical suitability // International journal of biological macromolecules. 2017. Vol. 105(Pt 1). P. 1310–1314. https://doi.org/10.1016/j.ijbiomac.2017.07.152","10.\tBasic statistics and Student's t-test // Portal of knowledge. StatSoft. URL: http://statistica.ru/local-portals/medicine/osnovnye-statistiki-i-t-kriteriy-styudenta/"]}
- Published
- 2022
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16. The Reliability of Swipe/Wipe Classification and Directionality Determination Methods in Bloodstain Pattern Analysis.
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Yuen, Sita K.Y., Taylor, Michael C., Owens, Glynn, and Elliot, Douglas A.
- Subjects
- *
BLOODSTAIN pattern analysis , *FORENSIC sciences , *BLIND experiment , *TARRING & feathering , *FORENSIC hematology , *CRIME analysis - Abstract
Swipe and wipe are types of transfer patterns commonly encountered at bloodied scenes. So far, there have been little published data on the reliability of evaluating these patterns. In this study, 36 bloodstain patterns were randomly assigned to 12 analysts in three separate trials, and the analysts were required to evaluate the pattern type and directionality. The results revealed that correct classifications of patterns type were problematic, with an overall error rate of 32%. Wipes created from wet bloodstains were the most difficult to identify due to the absence of signs of alteration. The directionality of swipes made with a gloved finger had a 100% success rate; however, for swipes made with cloth, the analysts mistook the direction in nearly every case, which is of significant concern, considering these are common patterns at crime scenes. This study suggested there is a need for revising the current protocols for interpretation of these pattern types. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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17. Study on Frictional Characteristics of Medical Wipes in Contact with Mechanical Skin Equivalents.
- Author
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Ramamurthy, Pasupathy, Chellamani, Kandan Perumal, Dhurai, Bharaathi, and Subramaniam, Venkataraman
- Subjects
NONWOVEN fabric wipes ,SURFACE roughness measurement ,STATIC friction ,VISCOSE process ,POLYURETHANES - Abstract
The optimum surface and frictional properties of textiles depend on their specific application. In this study, we examined the frictional behaviour of medical wipes against 15 mechanical near skin equivalents using synthetic leather material and bovine leather. The frictional behaviour characteristics, both static and kinetic, were evaluated at four different normal loads. It was seen that the static and kinetic frictional coefficients decrease with an increasing normal load for all the reference candidates studied. Higher friction was experienced for the movement of the cotton and viscose wipe against leather than that for synthetic polyurethane (PU) and silicone material.The friction of the wipe against any equivalent skin material was found to be dependent on its surface nature and the morphology of the material against which it is in contact and moves. Friction is necessary in real-time use for a wipe to have an inherent frictional resistance for movement against skin during use. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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18. Understanding Exposures to Volatile and Semivolatile Organic Compounds in Indoor Environments
- Author
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Parthasarathy, Srinandini
- Subjects
Environmental health ,Environmental engineering ,Dermal ,Inhalation ,Squalene ,SVOCs ,VOCs ,Wipe - Abstract
Humans spend most of their time indoors, in residences and commercial buildings. In this thesis, I evaluate exposures to volatile (VOCs) and semivolatile organic compounds (SVOCs) in indoor environments. I use a combination of literature review and evaluation, mechanistic modeling, and skin-wipe collection and analysis to develop an understanding of the role of indoor air as an exposure medium for inhalation and passive dermal uptake of pollutants. This dissertation explores three related research topics on indoor environments and human exposures. In Chapter 2, I conduct a comprehensive review of reported measurements of pollutants found in commercial buildings. I used the literature review to estimate concentration ranges that can be compared to health-based exposure limits as basis for hazard assessment. I use the regulatory exposure limits set by government agencies to calculate hazard indices as the ratio of observed concentrations to regulatory standards. I also compare the odor and pungency thresholds of individual pollutants to observed concentrations to evaluate their potential to exceed odor thresholds. The hazard evaluation identifies the potential for health impacts at concentrations commonly found in commercial buildings. This analysis focuses exclusively on VOCs and SVOCs in commercial buildings and identified a limited set of pollutants that pose health concerns. I also characterize the selected pollutants in terms of the chemical properties that,affect partitioning to various indoor surfaces, and subsequently their fate and transport in indoor environments. Based on chemical properties and indoor fate, I grouped the pollutants into five groups. I use an hierarchical k-means analysis based on octanol-air partitioning coefficient, octanol-water partitioning coefficient, air-water partitioning coefficient, and molecular weight. The pollutants in each group are expected to behave similarly in indoor environments. In Chapter 3, I evaluate the role of buildings operation parameters such as ventilation and filtration in limiting exposures to pollutants originating from indoor and outdoor sources. I use a simple well-mixed-air model of an indoor space to study the impact of ventilation on concentrations of ozone, nitrogen dioxide, carbon monoxide, and radon. I employ a chemical-thermodynamics-(fugacity)-based mass balance model in conjunction with a particle mass balance to study the fate and transport of particulate matter, VOCs, and SVOCs. The fugacity mass balance model accounts for chemical partitioning among air, air-borne particles, and indoor surfaces. I ran the fugacity model with indoor and outdoor source of VOCs and SVOCs and indoor and outdoor sources of particulate matter. I evaluate the consequent inhalation exposures these sources with two outcome metrics, intake fraction (iF) for indoor sources and indoor/outdoor concentration ratio for outdoor sources. The exposure to particulate matter of indoor and outdoor origin was evaluated using the outcome metrics iF and the indoor proportion of outdoor particles (iPOP). The model evaluation shows that ventilation is most effective at controlling exposures to VOCs that have an indoor source. Filtration is seen to be effective at controlling exposures to particulate matter and SVOCs that partition preferentially onto particulate matter. In Chapter 4, I explore the role of indoor air in delivering SVOCs to human occupants through passive dermal uptake. I collected wipe samples from thirteen subjects who were randomly chosen. For each subject, I collected three sequential wipe samples from the forehead and one sample from the palm. I analyzed the samples for a suite of SVOCs and skin lipids (squalene and sapienic acid) in an analytical laboratory using gas chromatography and liquid chromatography. All forehead wipe samples contained SVOCs indicating that air to skin transfer of pollutants for passive dermal uptake could be a significant exposure pathway for SVOCs. Because skin lipid concentrations decrease with depth the quantitation of skin lipid concentrations from each wipe allowed me to estimate the depth of sampling by each skin wipe. This is the first study to quantitatively evaluate the depth of sampling by skin wipes. I use the experimental results together with a theoretical model to explore the potential role of skin as a passive sampler for short-term personal exposures, indoors. For this I develop a metric called the equivalent time of exposure (ETE) to study the usefulness of sequential skin wipe samples as a passive sampler. I used partitioning coefficients from air to skin surface, combined with a dynamic skin mass transport model, to study the theoretical transport of pollutant through the stratum corneum. I compare the modeled concentrations to measured concentrations, at comparable depths. The ETE is the amount of time to which the subject would have to be exposed to a constant air concentration to attain the observed skin-wipe concentration depth profile in the stratum corneum. Based on the ETE, I find that skin wipe samples could be indicative of exposures up to 6 hours prior to wipe sampling, depending on the diffusion coefficient of the pollutant. The overarching goal of this research is to evaluate the role of indoor air in mediating the transfer to human receptors of pollutants released indoors or brought indoors from outdoor sources. The indoor air mass controls the fate and transport of pollutants in indoor spaces, and the rate of delivery of pollutants for inhalation and dermal uptake. The research highlights the important role of air-to-surface and air-to-particle partitioning in facilitating or mitigating source-receptor relationships. The work illustrates future research opportunities for tracking the complex web of indoor/outdoor pathways that bring pollutants into the human environment and into the blood and other viable tissues of the human population.
- Published
- 2016
19. Efficacy of removing bacteria and organic dirt from hands – a study based on bioluminescence measurements for evaluation of hand hygiene when cooking
- Author
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Paula Teixeira, Solveig Langsrud, Daniela Borda, Corina Neagu, Anca Ioana Nicolau, Octavian Augustin Mihalache, and Veritati - Repositório Institucional da Universidade Católica Portuguesa
- Subjects
Washing ,greasy hand ,Health, Toxicology and Mutagenesis ,Colony Count, Microbial ,Greasy hands ,cleaning ,Washing hands ,Soap ,0302 clinical medicine ,Hygiene ,Hand Hygiene ,wipe ,Cooking ,030212 general & internal medicine ,media_common ,0303 health sciences ,Pulp and paper industry ,6. Clean water ,3. Good health ,Warm water ,Medicine ,Greasy hand ,Hand Disinfection ,2019-20 coronavirus outbreak ,Coronavirus disease 2019 (COVID-19) ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,media_common.quotation_subject ,Cleaning ,Wipe ,Soaps ,Article ,03 medical and health sciences ,soap ,Humans ,washing ,Rinsing ,Pandemics ,Hand disinfection ,Bacteria ,SARS-CoV-2 ,030306 microbiology ,Public Health, Environmental and Occupational Health ,technology, industry, and agriculture ,COVID-19 ,Dirt ,Hand ,rinsing ,Luminescent Measurements ,Environmental science - Abstract
The objective of this study was to evaluate the efficacy of dirt removal (bacteria and organic matter) of several hand-cleaning procedures. The results from the hand hygiene experiment indicated that washing hands with warm water and soap for 20 s is the most effective method investigated when hands are either dirty or greasy. Even if not proper washing, rinsing under running water for 5 s is a cleaning procedure that may significantly reduce the probability of cross-contamination, as it removes 90% of the hands’ dirt. Although less effective than water and soap, the usage of antibacterial wipes was significantly more effective than wet wipes, indicating that they are a better choice when water and soap are not available. The results of this study enable us to inform consumers about the effectiveness of hand-cleaning procedures applied in their homes when cooking. Moreover, it can make consumers understand why, during the COVID-19 pandemic, authorities recommended washing hands as a preventive measure of infection and using an anti-bacterial hand gel or wiping hands with an antimicrobial wipe if water and soap are not available.
- Published
- 2021
20. An in vitro comparison of standard cleaning to a continuous passive disinfection cap for the decontamination of needle-free connectors
- Author
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Casey, Anna L., Karpanen, Tarja J., Nightingale, Peter, and Elliott, Tom S. J.
- Published
- 2018
- Full Text
- View/download PDF
21. Contact allergy caused by isothiazolinone derivatives: an overview of non-cosmetic and unusual cosmetic sources
- Author
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Aerts, Olivier, Goossens, An, Lambert, Julien, and Lepoittevin, Jean-Pierre
- Published
- 2017
- Full Text
- View/download PDF
22. An in vitro comparison of standard cleaning to a continuous passive disinfection cap for the decontamination of needle-free connectors
- Author
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Tom S.J. Elliott, Tarja J. Karpanen, Anna L. Casey, and Peter Nightingale
- Subjects
Microbiology (medical) ,Staphylococcus aureus ,Colony Count, Microbial ,Isopropyl alcohol ,Wipe ,030501 epidemiology ,Statistics, Nonparametric ,lcsh:Infectious and parasitic diseases ,2-Propanol ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Bloodstream infection ,Chlorhexidine gluconate ,Humans ,Medicine ,lcsh:RC109-216 ,Pharmacology (medical) ,030212 general & internal medicine ,Decontamination ,Log10 reduction ,Needle free ,Cross Infection ,Chromatography ,business.industry ,Research ,Chlorhexidine ,Public Health, Environmental and Occupational Health ,Equipment Design ,Human decontamination ,Disinfection ,Infectious Diseases ,chemistry ,Disinfection cap ,Equipment Contamination ,Needle-free connectors ,0305 other medical science ,business ,Microbial decontamination ,Disinfectants ,medicine.drug - Abstract
Background The optimal decontamination method for needle-free connectors is still unresolved. The objective of this study was to determine if a continuous passive disinfection cap is as effective as standard cleaning for the microbial decontamination of injection ports of two types of needle-free connectors. Methods The injection ports of needle-free connectors were inoculated with Staphylococcus aureus and allowed to dry. Disinfection caps containing 70% (v/v) isopropyl alcohol (IPA) were attached to the connectors for one, three or 7 days and were compared with needle-free connectors cleaned with 2% (w/v) chlorhexidine gluconate (CHG) in 70% (v/v) IPA. The number of S. aureus remaining on the injection ports was evaluated. Median log10 reductions and 95% confidence interval (CI) were calculated and data analyzed using the Mann-Whitney test. Results The application of the disinfection cap resulted in a significantly higher reduction in S. aureus than the 2% (w/v) CHG in 70% (v/v) IPA wipe, achieving a > 5 Log10 reduction in CFU at each time point. Conclusions The disinfection caps resulted in a significantly higher reduction in S.aureus on the injection ports when compared to the use of a 2% (w/v) CHG in 70% (v/v) IPA wipe. This offers an explanation for the lower rates of central-line associated bloodstream infection (CLABSI) associated with the use of disinfection caps reported in clinical studies.
- Published
- 2018
23. Efficacy of Removing Bacteria and Organic Dirt from Hands-A Study Based on Bioluminescence Measurements for Evaluation of Hand Hygiene When Cooking.
- Author
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Mihalache OA, Borda D, Neagu C, Teixeira P, Langsrud S, and Nicolau AI
- Subjects
- Bacteria, Colony Count, Microbial, Cooking, Hand, Hand Disinfection, Humans, Luminescent Measurements, Pandemics, SARS-CoV-2, Soaps, COVID-19, Hand Hygiene
- Abstract
The objective of this study was to evaluate the efficacy of dirt removal (bacteria and organic matter) of several hand-cleaning procedures. The results from the hand hygiene experiment indicated that washing hands with warm water and soap for 20 s is the most effective method investigated when hands are either dirty or greasy. Even if not proper washing, rinsing under running water for 5 s is a cleaning procedure that may significantly reduce the probability of cross-contamination, as it removes 90% of the hands' dirt. Although less effective than water and soap, the usage of antibacterial wipes was significantly more effective than wet wipes, indicating that they are a better choice when water and soap are not available. The results of this study enable us to inform consumers about the effectiveness of hand-cleaning procedures applied in their homes when cooking. Moreover, it can make consumers understand why, during the COVID-19 pandemic, authorities recommended washing hands as a preventive measure of infection and using an anti-bacterial hand gel or wiping hands with an antimicrobial wipe if water and soap are not available.
- Published
- 2021
- Full Text
- View/download PDF
24. Detection of fuel-oxidizer explosives utilizing portable capillary electrophoresis with wipe-based sampling.
- Author
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Krauss ST, Forbes TP, Lawrence JA, Gillen G, and Verkouteren JR
- Subjects
- Explosive Agents chemistry, Explosive Agents isolation & purification, Limit of Detection, Nitrates chemistry, Perchlorates chemistry, Powders, Electrophoresis, Capillary methods, Explosive Agents analysis
- Abstract
Portable analytical instrumentation that can provide an alarm indication for the presence of explosives and related components is critical for the identification of explosives-based hazards and threats. Many explosives incident reports involve an inorganic oxidizer-fuel mixture which can include pyrotechnics, fireworks, flash powders, black powders, black powder substitutes, and improvised or homemade explosives. A portable CE instrument with targeted analysis of common inorganic oxidizer ions, for example, chlorate, perchlorate, and nitrate, was used here as a rapid detection platform. Unlike frequently used gas-phase separation and detection instrumentation such as ion mobility spectrometry (IMS), an automated liquid extraction mechanism is required for CE separation using acetate paper sample collection wipes. Target inorganic oxidizers were inkjet-printed onto sample wipes to investigate instrument response relative to the collected analyte spatial distribution. Overall, analyte signal intensities increased with off-center sample deposition due to improved sample extraction from wipes and no change in response was observed for varied array distributions across wipes. The system demonstrated sub 200 ng detection limits for all target analytes, with further improvement when normalizing to an internal standard., (Published 2020. This article is a U.S. Government work and is in the public domain in the USA.)
- Published
- 2020
- Full Text
- View/download PDF
25. Polybrominated diphenyl ether (PBDE) concentrations and resulting exposure in homes in California: relationships among passive air, surface wipe and dust concentrations, and temporal variability
- Author
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Walter Weathers, Nicolle S. Tulve, Richard S. Jones, Irva Hertz-Picciotto, Andreas Sjödin, Xiangmei May Wu, Deborah H. Bennett, Maribel Colón, Matthew S. Clifton, and Rebecca E. Moran
- Subjects
Adult ,Environmental Engineering ,business.product_category ,Time Factors ,Wipe ,Medical and Health Sciences ,Article ,California ,chemistry.chemical_compound ,Polybrominated diphenyl ethers ,Engineering ,Air concentration ,Air Pollution ,Floors and Floorcoverings ,Halogenated Diphenyl Ethers ,Residential environment ,Vacuum cleaner ,Humans ,Two sample ,Indoor ,Child ,Preschool ,Flame Retardants ,Aged ,Building & Construction ,Diphenyl ether ,Public Health, Environmental and Occupational Health ,Age Factors ,Temporal variability ,Dust ,Building and Construction ,Environmental exposure ,Environmental Exposure ,Middle Aged ,Health Effects of Indoor Air Pollution ,Congener ,chemistry ,Environmental chemistry ,Air Pollution, Indoor ,Child, Preschool ,Housing ,Earth Sciences ,Environmental science ,business ,Fire retardant ,Environmental Monitoring - Abstract
Polybrominated diphenyl ethers (PBDEs) are used as flame retardants in furniture foam, electronics, and other home furnishings. A field study was conducted that enrolled 139 households from California, which has had more stringent flame retardant requirements than other countries and areas. The study collected passive air, floor and indoor window surface wipes, and dust samples (investigator collected using an HVS3 and vacuum cleaner) in each home. PentaBDE and BDE209 were detected in the majority of the dust samples and many floor wipe samples, but the detection in air and window wipe samples was relatively low. Concentrations of each PBDE congener in different indoor environmental media were moderately correlated, with correlation coefficients ranging between 0.42 and 0.68. Correlation coefficients with blood levels were up to 0.65 and varied between environmental media and age group. Both investigator-collected dust and floor wipes were correlated with serum levels for a wide range of congeners. These two sample types also had a relatively high fraction of samples with adequate mass for reliable quantification. In 42 homes, PBDE levels measured in the same environmental media in the same home 1year apart were statistically correlated (correlation coefficients: 0.57-0.90), with the exception of BDE209 which was not well correlated longitudinally.
- Published
- 2015
26. TIDY UP YOUR OFFICE FOR SPRING.
- Author
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MARCIANO, ROB and JOHNSON, TORY
- Abstract
ROB MARCIANO (ABC NEWS) (Off-camera) Well, spring is finally here. And it's the weekend, I hope you're enjoying it. But the work week just around the corner. Who better to give us some tips on how to tidy up your work space for spring than Tory Johnson? You're now our workplace expert, Tory. What's the first thing we should be doing for spring? [ABSTRACT FROM PUBLISHER]
- Published
- 2016
27. PRIVACY RISKS OF SELLING YOUR PHONE.
- Author
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HARRIS, DAM and BENITEZ, GIO
- Abstract
DAN HARRIS (ABC NEWS) (Off-camera) Back now at almost 7:41 with "GMA Investigates" how to wipe your cell phone clean before you sell it. It could be packed with important personal information, even if you think you've erased everything. ABC's Gio Benitez is here with much more on how you can protect yourself. Hey, Gio, good morning. [ABSTRACT FROM PUBLISHER]
- Published
- 2014
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