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Appointment scheduling is critical for logistic parks of manufacturing industry firms to manage inventory turnover and schedule service objects. This work studies the appointment scheduling problem of a logistic park considering truck heterogeneity and order fulfillment delay, where the number of time windows in a day, the number of each type of appointment slot, and the service schedule in each time window are decided. The objective is to minimise the expected total cost of the truck waiting time, inventory, and overtime. We introduce a weighted shortest processing time first scheduling rule to determine the service sequence in each time window and prove that it generates optimal scheduling solutions. Based on our proposed scheduling rule, we develop a recursive calculation to formulate the cost function, which provides a tractable approach to solving combinatorially complex problems. The proposed model is solved by a dual-selection based genetic algorithm (DSGA). The performance of the DSGA is validated by comparing it to a genetic algorithm using a single tournament selection operation. Our experimental results show that the DSGA enlarges the size of subgroups with better fitness and therefore performs satisfactorily. [ABSTRACT FROM AUTHOR]

Online news can be shared and promoted via social media, mobile push messages, newsletters, "most read" boxes, or the like. This can result in feedback loops, in which views attract even more views. Using full click logs for five regional newspapers in the Netherlands, spanning $N_{{\rm views}} =$ N views = 12,108,263 views of $N_{{\rm articles}}=$ N articles = 17,982 articles for each minute over the course of 13 weeks, we shed light on potential feedback loops. While article placement and promotion decisions indeed increase their views, we find these effects to be short-lived, contradicting the feedback-loop hypothesis. Exceptions in line with the feedback-loop hypothesis mostly concern social media: If an article is spread via social media, it is not only clicked more, but also clicked on for a longer period of time. [ABSTRACT FROM AUTHOR]

Background and Aims: Although the evidence is uncertain, existing estimates for hepatitis C virus (HCV) in sub‐Saharan Africa (SSA) indicate a high burden. We estimated HCV seroprevalence and viraemic prevalence among the general population in SSA. Methods: We searched Medline, Embase, Web of Science, APA PsycINFO, and World Health Organization Africa Index Medicus for community‐based studies. Study quality was assessed using the Joanna Briggs Institute critical appraisal tool, and heterogeneity using the index of heterogeneity (I2). Two approaches were deployed. First, we used random‐effects meta‐analysis to pool prevalence. Second, to derive representative estimates, we weighted each country's HCV seroprevalence using 2021 United Nations country population sizes. Results: We synthesized 130 studies. Overall, SSA HCV seroprevalence from the random‐effects model was 4.17% (95% confidence interval [CI]: 3.71–4.66, I2 = 99.30%). There were no differences between males (4.31%) and females (4.03%). Seroprevalence was 2.25%, 3.31%, and 16.23% for ages ≤20, 21–64, and ≥65 years, respectively, and was higher in rural (6.63%) versus urban (2.93%). There was indication of decrement overtime from 5.74% to 4.35% to 3.03% in the years 1984–2000, 2001–2014, and 2015–2023, respectively. The weighted overall SSA HCV seroprevalence was estimated to be 2.30% (95% CI: 1.59–3.00) with regional variation: Africa‐Southern (.79%), Africa‐Central (1.47%), Africa‐Eastern (2.71%), and Africa‐Western (2.88%). HCV viremia among HCV seropositives was 54.77% (95% CI: 47.80–61.66). Conclusions: HCV seroprevalence in SSA remains high. Populations aged ≥65 years, rural communities, Africa‐Western, and some countries in Africa‐Central and Africa‐Eastern appear disproportionately affected. These results underline the need for governmental commitment to achieve the 2030 global HCV elimination targets. [ABSTRACT FROM AUTHOR]

High cardiorespiratory fitness (CRF) has been associated with a lower risk of depression, anxiety, and cerebrovascular disease. The aim was to explore CRF changes over-time associated with these outcomes. This large-scale prospective cohort study, using data from Swedish population-wide registries and databases (during 1972–2020), included men (n =131,431), with measures of estimated CRF (estCRF) in late adolescence (maximal cycle test) and adulthood (submaximal cycle test) (mean years between 24.6, SD 8.8). The study explored how change in estCRF was associated with incident depression, anxiety, and cerebrovascular disease using Cox proportional hazards models. Analyses were performed in 2023. Higher estCRF in late adolescence and adulthood were associated with a lower risk of incident depression, anxiety, and cerebrovascular disease later in life. For all three outcomes, an increase in estCRF (mL/min/kg and z-score) between the two-time points was associated with a lower risk. Further, decreasing from moderate or high estCRF in adolescence to low estCRF in adulthood, compared to staying at a moderate or high level, was associated with a higher risk of depression and anxiety (HR: 1.24 95% CI 1.07–1.45 and 1.25 95% CI 1.06–1.49, respectively). Conversely, increasing from moderate to high estCRF was associated with a lower risk of incident anxiety (HR: 0.84 95% CI 0.71–0.99). The findings indicate that there is a longitudinal association between negative change in estCRF and increased risk of depression, anxiety, and cerebrovascular disease later in life. Decreasing levels of estCRF could be a helpful indicator when identifying these disorders at a population level. [ABSTRACT FROM AUTHOR]

Proteomic investigations result in high dimensional datasets, but integration or comparison of different studies is hampered by high variances due to different experimental setups. In addition, cell culture conditions can have a huge impact on the outcome. This study systematically investigates the impact of experimental parameters on the proteomic profiles of commonly used cell lines—A549, differentiated THP-1 macrophage-like cells, and NR8383—for toxicity studies. The work focuses on analyzing the influence at the proteome level of cell culture setup involving different vessels, cell passage numbers, and post-differentiation harvesting time, aiming to improve the reliability of proteomic analyses for hazard assessment. Mass-spectrometry-based proteomics was utilized for accurate protein quantification by means of a label-free approach. Our results showed that significant proteome variations occur when cells are cultivated under different setups. Further analysis of these variations revealed their association to specific cellular pathways related to protein misfolding, oxidative stress, and proteasome activity. Conversely, the influence of cell passage numbers on the proteome is minor, suggesting a reliable range for conducting reproducible biological replicates. Notable, substantial proteome alterations occur over-time post-differentiation of dTHP-1 cells, particularly impacting pathways crucial for macrophage function. This finding is key for the interpretation of experimental results. These results highlight the need for standardized culture conditions in proteomic-based evaluations of treatment effects to ensure reliable results, a prerequisite for achieving regulatory acceptance of proteomics data. [ABSTRACT FROM AUTHOR]

Using data from China Migrants Dynamic Survey (CMDS), this study finds that migrants' housing expenditure pressure is negatively associated with their physical health. And the impact is mainly reflected in three aspects: the crowding-out effect, overtime working effect, and psychological anxiety effect. The association between migrants' housing expenditure pressure and their physical health varies across individual characteristics and home ownership types. Our findings carry many policy implications from the perspective of improving the physical health level of migrants. [ABSTRACT FROM AUTHOR]

Introduction: Cerebral malaria (CM) is a devastating disease and better understanding of etiologies of the resulting neurologic injury is needed. The purpose of this study is to describe the day-to-day (DTD) pulsatility index (PI) change measured by transcranial Doppler ultrasound (TCD), a novel measure of cerebral and vascular changes, in children with CM. Methods: A retrospective analysis of 122 children in sub-Saharan Africa with CM and 3 or more sequential TCD measurements was performed. Variability of DTD PI change was calculated as a measure of changes in vasculature overtime. Neurologic outcome was determined by the Pediatric Cerebral Performance Category (PCPC) score, a measure of neurologic function. Results: Of the 122 participants, 77.9% had a good neurologic outcome (no neurologic sequelae), and 22.1% had a poor outcome (neurologic sequelae or died). Patients who had a poor neurologic outcome had higher levels of variability of DTD PI change in the right middle cerebral artery (MCA) (0.14 ± 0.21) and left MCA (0.17 ± 0.41) compared to those who had a good neurologic outcome (0.1 ± 0.1 and 0.11 ± 0.19, respectively). A higher variability of both left and right MCA DTD PI change was also associated with higher brain volume assessed through neuroimaging. Discussion: Variability of DTD PI change may provide early prognostic information regarding PCPC outcomes and brain volume changes seen in CM patients. Expanded research on pathophysiologic contributors to variability of DTD PI changes in children with CM is warranted. [ABSTRACT FROM AUTHOR]

Background: Risdiplam is a validated treatment for adult SMA patients, but clear guidelines concerning functional assessment at baseline and during the follow-up are still limited, especially in terms of sensible and validated outcome measures able to capture minimal changes in motor performances induced by therapy. The aim of this work is to describe the effect of Risdiplam on a cohort of 6 adult type 2 and type 3 SMA patients, using Motor Function Measure (MFM32) as a standardized scaleto quantify the motor improvements induced by therapy. Results: Risdiplam at the dose of 5 mg/daily was administered to a population of 6 (4 F;2 M) type 2 (N = 4) and type 3 (N = 2), adult SMA patients. Two patients were previously treated by Nusinersen, later suspended due to side effects. At baseline, all patients received a neuromuscular evaluation and a MFM32 assessment. After the beginning of treatment, we evaluated MFM32, patient reported outcomes (PROs), and adverse events over 7–27 months of follow-up. The MFM32 showed an increased score ranging from + 2.16% to + 7.29% in 4 patients. The improvement was maintained overtime, with two patients presenting the longest follow-up period of 24 and 27 months respectively. Subdomain D3 was ameliorated in 66.6% of patients. Two patients previously treated with Nusinersen maintained the pre-Risdiplam scores. The HFMSE was also performed and failed to show significant improvements after treatment. All patients reported subjective ameliorations. The commonest PROs were improvements in breath fatigue, voice's intelligibility, hand strength and dexterity. Adverse effects were mild and decreased over time. Conclusions: Risdiplam is a well-tolerated treatment in our cohort of adult type 2 and type 3 SMA patients and resulted in improvement or stabilization in motor functions. MFM32 proved to be sensitive to detect changes induced by therapy. Subjective meaningful improvements were sustained overtime especially in bulbar functions, breath fatigue and distal motor abilities. [ABSTRACT FROM AUTHOR]

Population studies have shown that the infant's microbiome and metabolome undergo significant changes in early childhood. However, no previous study has investigated how diverse these changes are across subjects and whether the subject-specific dynamics of some microbes correlate with the over-time dynamics of specific metabolites. Using mixed-effects models, and data from the ABC study, we investigated the early childhood dynamics of fecal microbiome and metabolome and identified 83 amplicon sequence variants (ASVs) and 753 metabolites with seemingly coordinated trajectories. Enrichment analysis of these microbes and molecules revealed eight ASV families and 23 metabolite groups involving 1032 ASV-metabolite pairs with their presence-absence changing in a coordinated fashion. Members of the Lachnospiraceae (464/1032) and metabolites related to cholestane steroids (309/1032) dominated proportional shifts within the fecal microbiome and metabolome as infants aged. Longitudinal analyses of subject-specific dynamics in infants' microbiome and metabolome identified microbes and metabolites with seemingly coordinated dynamics. [ABSTRACT FROM AUTHOR]

Appointment scheduling (AS) plays a crucial role in outpatient clinic management. Traditional methods involve patient grouping using pre-defined rules and scheduling based on these groups. However, pre-defined rules may not adequately capture the heterogeneity in patients' service times (i.e., consultation duration). Advanced machine learning (ML) methods can address individual-level heterogeneity but pose challenges for practical scheduling. To strike a balance, we propose a data-driven AS decision support system, Cluster-Predict-Schedule (CPS), integrating both supervised and unsupervised ML for efficient patient grouping and scheduling. The novelty of CPS lies in its adaptability to service time heterogeneity through a data-driven approach, determining patient groups based on data rather than pre-defined rules. Additionally, CPS includes a generic and efficient algorithm for generating appointment templates adaptable to any number of patient groups. Our system's efficacy is demonstrated using a real-world dataset. Evaluated by the weighted sum of patient wait times, physician idle time, and overtime, CPS achieves up to 15.0% cost reduction compared to the FCFA (first-call, first-appointment) scheme and over 4.7% savings against the common New/Return classification with traditional sequencing candidate (TSC) rules. In addition, CPS enhances outpatient operational efficiency without compromising fairness. [ABSTRACT FROM AUTHOR]

America is said to be more polarized than ever before, and extensive research examines the causes and effects of political polarization. A less studied but more pronounced trend is that citizens perceive society and politics as sharply divided. We focus on news exposure as a key reason for these perceptions. We disentangle the unique effects of exposure to partisan outlets and to news coverage of polarization in general, whether in partisan or centrist news media. We rely on 9 months of online behavioral data (127,400,000 visits) from large samples in the U.S. and Poland (total N = 2,462 & 2,120), paired with a three-wave panel survey on participants' attitudes and perceptions. We measure individual exposure, over-time and unobtrusively, to partisan outlets as well as to news coverage of polarization through a fine-tuned BERT-based machine learning classifier. We find that both exposures increase perceived polarization, independently, in both countries. Yet, in both contexts, it is news coverage of polarization, regardless of whether it is ideologically left, right, or centrist news outlets, that is the strongest driver of perceived polarization. These changes are confined to personal-level polarization (perceived distance between oneself and members of the opposing party), while no measure significantly influences perceptions of society, more generally, as being polarized. These findings have important implications for our understanding of how the media’s increasing tendency to focus on conflict as a central reporting frame can be the driver of often exaggerated perceptions of partisan divisions. [ABSTRACT FROM AUTHOR]

Conspiracy theories accusing specific groups of secret malevolent actions can foster a perception of the world as a dangerous place. In our research, we contend that both adherence and exposure to conspiracy beliefs can serve as a potential cause of certain psychological problems in the form of paranoid thoughts. This hypothesis was tested in three studies conducted among Polish and British participants. In Study 1 (longitudinal, N = 603), we found that conspiracy beliefs exerted a positive overtime effect on paranoid thoughts. Experimental studies 2 (N = 384) and 3 (N = 445), showed that being exposed to conspiracy theories (vs. control stimuli) heightened paranoid thoughts. In Study 3, we proposed a potential mechanism explaining this effect, according to which exposure to conspiracies increased paranoid thoughts via only negative intense emotions. Our work adds to the discussion on the consequences of conspiracy beliefs and has implications for mental health research, underlining the importance of designing interventions limiting the adverse effects of conspiracy beliefs. [ABSTRACT FROM AUTHOR]

Objectives: To investigate long‐term alveolar ridge bone changes in patients treated with the split‐crest technique (SCT) with simultaneous implant placement. Materials and Methods: Alveolar ridge width (ARW) was measured with a caliper immediately before (ARW1) and after SCT (ARW2) with a caliper. Existing CBCT scans taken at least 5 years postoperatively were used to assess the healed ARW (ARWF), buccal bone thickness (BBT), and lingual/palatal bone thickness (L/PBT) at 0, 3, and 5 mm apically from implant platform level (IPL). The distance between IPL and buccal bone crest (IPL‐BBC) was also measured. Findings were compared with Wilcoxon and Student's t tests (p <.05). Results: Records of thirty patients with 85 implants were included. Eleven patients (31 implants) presented CBCT scans taken in two separate occasions, resulting in 116 measurements. Tomographic follow‐up ranged from 5 to 18 years (11.5 ± 4.18 years). Mean ARW increased from 3.2 ± 0.6 to 6.6 ± 0.48 mm after SCT, but significantly reduced overtime to 4.46 ± 0.83 mm (ARWF) (p <.0001). Mean BBT was 0.5 ± 0.9, 1.3 ± 0.9, and 2.0 ± 1.2 mm, while mean L/PBT was 0.9 ± 0.7, 1.6 ± 0.9, and 2.1 ± 1.0 mm at 0, 3, and 5 mm from IPL, respectively. IPL‐BBC distance varied up to 8.7 mm (1.4 ± 2.0 mm), with 56/116 measurements (51/85 implants) showing IPL‐BBC = 0 mm. Conclusion: Although SCT with simultaneous implant placement can predictably increase ARW postoperatively, ARW tended to significantly reduce over time, due to reductions in BBT and L/PBT, especially coronally. Nonetheless, 60% of the implants still presented some buccal bone at IPL. [ABSTRACT FROM AUTHOR]

This article seeks to explain why spatial policy in England has been so ineffective in recent decades. It offers a novel framework – 'Hyper-Active Incrementalism' – to conceptualise the way that public policy in this area is prone to being short-term, under-evaluated, reactive, fragmented, incremental and top-down. It applies this framework to a historical survey of spatial policy, offering a nuanced understanding of the causes of these pathologies. We argue that Hyper-Active Incrementalism helps explain the persistence of a range of Westminster pathologies, as it drives the ongoing dialectic relationship between over-centralisation and policy failure. The data drawn from our historical survey suggest that Hyper-Active Incrementalism has accelerated overtime, a dynamic of increasing governance fragmentation that contributes to the incoherence of the UK state. In conclusion, we argue that governments must learn from past failure not just in this policy area but also elsewhere, by adopting a system-wide approach to reform. [ABSTRACT FROM AUTHOR]

Prisons are stressful environments for both people living and working in them. Extant literature suggests that correctional staff have increased stress levels that lead to compromised physical health, mental health, social relationships, and increased emotional strain. This article reports on a project utilizing a modified Participatory Action Research (PAR) approach to understand the mechanisms that lead to increased stress levels among correctional officers who reported working overtime. The analysis utilizes organizational justice and social comparison frameworks to explore predictors of individual levels of stress among correctional officers working overtime in a Delaware prison. The findings indicate that individual-level stress spreads through perceptions of coworker's stress and is inversely related to perceived levels of organizational justice. This analysis is useful to prison administrators, leadership, in suggesting avenues to improve the climate of correctional environments. [ABSTRACT FROM AUTHOR]

In this paper, we examine the relationships between racial resentment and use of partisan media in the U.S. Our paper first examines the correlation between these two variables then tries to assess whether there are over-time relationships between them. Our paper first establishes that racial resentment is indeed associated with higher levels of using conservative media and lower levels of using liberal media. We then examine whether people's level of racial resentment drives their use or avoidance of specific media content or if using these different outlets changes people's levels of racial resentment. We find some evidence that racial resentment tends to be associated with avoiding liberal media outlets. By contrast, racial resentment does not predict changes in conservative media use. Moreover, we do not find that media use affects racial resentment. [ABSTRACT FROM AUTHOR]

Shoe manufacturing companies often use overtime work but neglect the impacts and importance of physical recovery time. Ergonomic methods aim to analyze this, but they focus on deterministic aspects, which limits their ability to evaluate working conditions amid variations over time. This research explores how a simulation model can mitigate these limitations and enhance analysis of overtime and physical recovery on worker absenteeism. The objective was developed a simulation model using System Dynamics (SD) to represent working conditions and assess the influence of overtime and recovery time in Brazil's footwear industry. An Ergonomic Analysis of Work was conducted in a large company's production cell. Using SD, were constructed a causal and simulation model to analyze three scenarios. An additional hour of work increased physical overload by 44%, leading to 5, 4 leave requests, and 48 days of absenteeism per year. Increasing recovery time by 15 min reduced overload to 38,96%, resulting in 4, 9 leave requests and 13,68 days of absenteeism. The SD simulation model mitigated the limitations of ergonomic methods in understanding the dynamic relationships over time, emphasizing the importance of actively managing overtime and physical recovery time. [ABSTRACT FROM AUTHOR]

China's fertility rate continues to decline despite government fertility policies. This study aims to explore the micro-level causes of China's declining fertility rate by examining the impact of changes in Chinese work patterns in recent years, particularly the prevalence of overtime work, on fertility intentions. Using data from the China Family Panel Studies (CFPS), this study examines the impact of overtime work on fertility intentions at both the provincial and urban levels. It also examines the specific mechanisms through which different types of overtime (e.g. weekend overtime, night shifts, on-call duty) affect fertility intentions. The results show that overtime work significantly inhibits fertility intentions, a trend that is consistent at both provincial and urban levels. Weekend overtime, night shifts, and on-call duties exhibit particularly pronounced inhibitory effects on fertility intentions. However, not all work arrangements negatively impact fertility intentions. Reasonable work schedules may even foster them. The research implies the need for policy measures to mitigate the negative effects of overtime work on fertility intentions. [ABSTRACT FROM AUTHOR]

Traditional varieties are a valuable tool in modern apple breeding. However, the use of synonyms and missing source documentation hinder an effective identification and conservation of relevant cultivars. During several projects, the authenticity and diversity of the apple cultivar collection of the German Fruit Genebank (GFG) was evaluated extensively. The trueness-to-type of 7890 apple trees was assessed on a pomological and molecular level. Pomological evaluations were performed by at least two experienced experts to identify the original cultivar names. On the molecular level, a set of 17 SSR markers was used to determine a unique genetic profile for each apple cultivar. The pomological and molecular characterization was expressed in terms of a comprehensive trueness-to-type criterion and the results were previously published as a well-curated dataset. In this study, the published dataset was analyzed to evaluate the quality and diversity of the apple collection of the GFG and highlight new findings based on phylogenetic and parentage analysis. The dataset contains 1404 unique genetic profiles corresponding to unambiguous cultivar names. Of these 1404 cultivars, 74% were assessed as true-to-type. The collection of diploid apple cultivars showed a high degree of expected heterozygosity (Hexp = 0.84). Genetic diversity in terms of year and location of origin was investigated with a STRUCTURE analysis. It was hypothesized that genetic diversity might decline overtime due to restrictive breeding programs. The results showed a shift dynamic between older and newer cultivars in one specific cluster, but no significant decrease in genetic diversity was observed in this study. Lastly, a parentage analysis was performed to check parental relationships based on historical research. Out of 128 parent–child trios, 110 trios resulted in significant relationships and reconfirmed the information from the literature. In some cases, the information from the literature was disproven. This analysis also allowed for readjusting the trueness-to-type criteria for previously undetermined cultivars. Overall, the importance of authenticity evaluations for gene bank cultivars was highlighted. Furthermore, the direct use of the dataset was shown by relevant investigations on the genetic diversity and structure of the apple cultivar collections of the GFG. [ABSTRACT FROM AUTHOR]

OBJECTIVES: This study aimed to evaluate the independent and interactive effects of changes in overtime and night shifts on burnout among nurses during the COVID-19 pandemic. METHODS: Nurses working in an Italian university hospital (N=317) completed the Maslach Burnout Inventory in September 2019 and again in December 2020. Based on hospital administrative data, changes in overtime and night shifts in the same years were categorized into three groups each. Linear regressions were used to estimate 2020 burnout differences between exposure groups, controlling for 2019 burnout levels, demographic and work-related characteristics, and to test the interaction between the two exposures. RESULTS: Nurses in the onset of high overtime group had higher emotional exhaustion [4.33, 95% confidence interval (CI) 1.74−6.92], depersonalization (2.10, 95% CI 0.49−3.71), and poor personal accomplishment (2.64, 95% CI 0.55−4.74) compared to stable low overtime nurses. Nurses in the increase in night shifts group had lower emotional exhaustion (-4.49, 95% CI -7.46− -1.52) compared to no night shift nurses. Interaction analyses revealed that this apparently paradoxical effect was limited to stable low overtime nurses only. Moreover, increases in night shifts were associated with higher depersonalization and poor personal accomplishment in nurses in the stable high overtime group. CONCLUSIONS: Increase in overtime is an independent risk factor for burnout among nurses, highlighting the need for specific regulations and actions to address it. Long-standing guidelines for the assignment of night shifts might have contributed to attenuate the impact of their increase on nurses’ mental health.

Background: Outpatient Clinics (OCs) are under pressure because of increasing patient volumes and provider shortages. At the same time, many patients with chronic diseases receive routine follow-up consultations that are not always necessary. These patients block access to care for patients that are in actual need for care. Pre-assessing patient charts has shown to reduce unnecessary outpatient visits. However, the resulting late cancellations due to the pre-assessment, challenge efficient alignment of capacity with actual patient demand, leading to either empty slots or overtime. This study aims to develop a method to analyse the effect of pre-assessing patients before inviting them to the OC. This involves 1) to select who should come and 2) to optimize the impact of pre-assessment on the schedule and efficient use of OC staff. Methods: This prospective mixed-methods evaluation study consists of 1) an expert meeting to determine a pre-assessment strategy; 2) a retrospective cohort study to review the impact of this strategy (12 months of a Dutch nephrology OC); 3) mathematical optimization to develop an optimal criteria-based scheduling strategy; and 4) a computer simulation to evaluate the developed strategy. Primary outcomes are the staff idle time and staff overtime. Secondary outcomes evaluate the number of weekly offered appointments. Results: The expert group reached consensus about the pre-assessment criteria. 875 (18%) of the realized appointments in 2022 did not meet the OC visit pre-assessment criteria. In the best performing scheduling strategy, 94 slots (87% of the available capacity) should be scheduled on a weekly basis. For this schedule, 26.8% of the OC weeks will experience idle time (μ =2.51, σ =1.44 appointment slots), and 21% of the OC weeks will experience overtime (μ =2.26, σ =1.65 appointment slots) due to the variation in patient appointment requests. Using the pre-assessment strategy combined with the best performing scheduling strategy under full capacity (108 slots), up to 20% increase in patient demand can be handled with equal operational performance. Conclusions: This evaluation study allows OC managers to virtually test operational impact of pre-assessment strategies on the capacity of their OC, and shows the potential of increasing efficient use of scarce healthcare capacity. Trial registration: Not applicable. [ABSTRACT FROM AUTHOR]

Despite the recent and sharp rise in psychedelic research, few studies have investigated how classic psychedelic use relates to employees' work-related outcomes. This is surprising given that the increased use, decriminalization, and legalization of classic psychedelics in the United States (U.S.) has the potential to impact both employees and their organizations. Addressing this gap, the current study explores how employees' lifetime psilocybin use relates to the amount of overtime they work, thereby offering insight into what current trends in psilocybin use could mean for businesses. Using pooled, cross-sectional data from the National Survey on Drug Use and Health (2002–2014) on 217,963 adults employed in the U.S. full-time, this study tests whether lifetime psilocybin use is associated with employees' number of overtime hours worked in the past week. After adjusting for sociodemographics and other substance use, a significant negative association is found between employees' lifetime psilocybin use and the amount of overtime they reported working. Specifically, the findings suggest that lifetime psilocybin use in the U.S. full-time working population is associated with an estimated 44,348,400 fewer overtime hours worked per year and may help explain recent findings linking employees' lifetime psilocybin use to a reduction in sick leave taken. [ABSTRACT FROM AUTHOR]

In most studies on news repertoires and the linkage between media use and (mis)perceptions of social and political matters, the use of political alternative media has not been included. In this paper, we therefore investigate how people combine both traditional and political alternative media into different media repertoires, and how these media repertoires are related to misperceptions. We rely on a two-wave panel survey, conducted in 2020 and 2021, with a probability-recruited sample of the Swedish population. Measures on the use of a wide range of media, including political alternative ones, are used to conduct a Latent Profile Analysis. This analysis distinguishes five media repertoires in the data. The results show that these repertoires coincide with different levels of misperceptions, with those dominated by TV use showing higher levels of misperceptions and those with higher newspaper and alternative media use showing lower levels of misperceptions. Results also show that media repertoires do not affect over-time changes in misperceptions. [ABSTRACT FROM AUTHOR]

This paper presents a model that examines sports teams' strategic choices about the extent of offense/defense to adopt in competing with other teams. The mathematical formulation adopted permits the derivation of a team's optimal strategy under different game scenarios (current score and time left to play), and team characteristics (playing at home or away, and each team's quality). A novel feature of the model is that teams can choose a strategy at several moments in the game, thereby incorporating a comprehensive dynamic element. The National Hockey League is used as an application. Optimal coaching behavior is derived in this setting, and the impact of rule changes is assessed. The study found that removing the overtime period, disproportionally increasing the rewards for a win, or removing the point that is currently awarded to the team that loses the shootout at the end of overtime, would all lead to the adoption of more offensive strategies during the game. That outcome is aligned with higher fan interest and team revenue. [ABSTRACT FROM AUTHOR]

Many firms use short-term capacity adjustments to deal with demand changes over time, and a broad literature assesses when and where to adjust capacity. This study highlights that this may be dependent on the type of capacity flexibility used to actually realize the adjustment. By comparing for the first-time capacity adjustments by speeding up processing rates, working in parallel, or using overtime, significant differences in the operational performance are identified, with the latter resulting in the best percentage tardy performance. This provides important insights for the interpretation of the existing literature, guides the future literature, and helps managers to make better decisions. [ABSTRACT FROM AUTHOR]

The detection efficiency (DE) of the World Wide Lightning Location Network (WWLLN) is evaluated in Southeast Asia by comparing WWLLN data with the Earth Network Total Lightning Network (ENTLN) data taking into account time, distance, and peak‐current parameters. The performance of WWLLN is evaluated in the months of November and December in two different years (2020–2021). These periods are selected to assess the change (if any) in DE overtime and the inclusion of new stations. The strokes between the two networks were considered matched if they fell within a time criterion of 100 µs and a location difference of 25 km. Using this criterion, 5.2 × 106 WWLLN strokes were matched with ENTLN cloud‐to‐ground (CG) lightning strokes in November‐December 2020, resulting in a DE of 32.9%. Similarly, 4.6 × 106 WWLLN strokes were found to match in November‐December 2021, yielding a DE of 36.5%. Analysis of the peak‐currents reveals that DE is lowest (<10%) for a peak‐current below ±10 kA. However, for peak‐current exceeding ±50 kA, the DE increases to ∼60%. During November‐December 2021, WWLLN reported 38.95 × 106 lightning strokes globally; amongst them, Dhaka station detected 0.5 × 106 strokes, contributing to a 1.3% increase in the global DE. Dhaka station detects most lightning strokes within 8 × 103 km, which diminishes to zero after 10 × 103 km. The Dhaka station recorded a larger number of strokes at longer detection distances during midnight (22:00–02:00) than during noon (10:00–14:00). The results signify a positive impact of the Dhaka station on WWLLN's DE during the mentioned period. Plain Language Summary: This comprehensive study delves into the detection efficiency (DE) of the World‐Wide Lightning Location Network (WWLLN) in Southeast Asia, compared to Earth Network Total Lightning Network (ENTLN) data. A matching strategy is involved to identify the matched strokes between two networks. Spanning key intervals in November‐December 2020 and 2021, this study unveils significant results, highlighting an enhanced DE in WWLLN. This investigation delves into the repercussions of adding or removing detection stations. Establishing a WWLLN station in Dhaka emerges as significant, detecting over 0.5 × 106 lightning strokes and contributing to a notable global DE augmentation during the investigation period. This study identified a total count of cloud‐to‐ground (CG) lightning strokes in the specified region during the investigation period, with a WWLLN DE for CG strokes. The study unveils nuanced DE dynamics based on peak‐currents, showing the lowest detection efficiency below for lower peak‐currents and a remarkable surpass for higher peak‐currents value. Key Points: In Southeast Asia, the detection efficiency of World Wide Lightning Location Network (WWLLN) improved by 3.6% in 1 year (2020–2021)In the region of interest, the detection efficiency of the WWLLN is lower than 10% for 10 kA peak‐currents but surpasses 60% for 50 kADuring November–December 2021, WWLLN Dhaka station detected 500 × 103 lightning strokes, contributing to a 1.3% increase in global detection efficiency [ABSTRACT FROM AUTHOR]

This study aims to determine the effect of overtime on employee performance, the effect of work environment on employee performance, the effect of overtime on employee performance mediated by job satisfaction, the effect of work environment on employee performance mediated by job satisfaction, and the effect of job satisfaction on employee performance. This research was conducted at PT Bio Farma (Persero) with a sample size of 237 people. The method used was quantitative with data collection techniques using questionnaires. Statistical testing used SEM PLS (Structural Equation Modeling Partial Least Square) to measure the relationship between variables. The results showed that the work environment and job satisfaction have a direct positive and significant effect on performance. Furthermore, overtime work and the work environment have a positive and significant indirect effect on performance through job satisfaction, while overtime work has a direct negative and nonsignificant effect on employee performance. This research can have good implications for companies and leaders in efforts to improve employee performance by implementing appropriate overtime work policies, maintaining a conducive work environment, and not neglecting job satisfaction as a positive booster for employees. [ABSTRACT FROM AUTHOR]

State socialist Vietnam formally embraced market reforms in the mid-1980s, and since then advancing marketization under the undisrupted rule of the Communist party. As marketization deepens, the party state's legitimacy continues to rest on socialist practices of governance, structures of feeling and visions of a class-free society. This political-economic context gives rise to struggles between market and socialist logics over the social question in an economy that now powers global production with raw material and cheap labour, much of which is migrant labour. This article highlights these struggles through an analysis of the public debates around the regulation of overtime work during the revision of the 1994 Labour Code by Vietnam's National Assembly in 2019, which foresees limiting it to ensure workers' well-being. While parties to the debate position themselves as pro-business or pro-workers, they all evoke socialist narratives of nation-building, solidarity and care while emphasizing the market ethos of competitiveness and productivity. In arguing for removing the limit, the pro-business camp highlights the workers' responsibility to contribute to the competitiveness of the country and their employers by working overtime to make up for their low productivity. In contrast, the pro-worker camp pleads for limiting overtime work on the grounds of workers' poor health and difficult family lives, portraying their sufferings as deserving compassion. Despite these contrasting justifications, both arguments are characterized by the assumption of self-responsibility as the mainstay of well-being and failure to acknowledge the deeper societal problems posed by the commodification of labour. [ABSTRACT FROM AUTHOR]

Background: Unpaid overtime—describing a situation where extra hours are worked but not paid for—is a common feature of the labor market that, together with other forms of wage theft, costs workers billions of dollars annually. In this study, we examine the association between unpaid overtime and mental health in the Canadian working population. We also assess the relative strength of that association by comparing it against those of other broadly recognized work stressors. Methods: Data were drawn from a survey administered to a heterogeneous sample of workers in Canada (n = 3691). Generalized linear models quantified associations between unpaid overtime, stress, and burnout, distinguishing between moderate (1−5) and excessive (6 or more) hours of unpaid overtime. Results: Unpaid overtime was associated with higher levels of stress and burnout. Relative to those working no unpaid overtime, men working excessive unpaid overtime were 85% more likely to report stress (prevalence ratios [PR]: 1.85, 95% confidence interval [CI]: 1.26−2.72) and 84% more likely to report burnout (PR: 1.84, 95% CI: 1.34−2.54), while women working excessive unpaid overtime were 90% more likely to report stress (PR: 1.90, 95% CI: 1.32−2.75) and 52% more likely to report burnout (PR: 1.52; 95% CI: 1.12−2.06). The association of excessive unpaid overtime with mental health was comparable in magnitude to that of shift work and low job control. Conclusions: Unpaid overtime may present a significant challenge to the mental health of working people, highlighting the potential role of wage theft as a neglected occupational health hazard. [ABSTRACT FROM AUTHOR]

The aim of this study is to identify women's perceptions of the main reasons for discrimination at work. Furthermore, the aim is to analyse the effects of public working time policies on gender equality and their impact on discrimination at work and on women's career paths. This article presents a framework for the topic through an analysis of documents and literature, as well as an exploratory study carried out in Portugal. Working time policies since 2011 in Portugal are examined and through an empirical study, the impact of overtime on women's work and careers is analysed. The documentary analysis carried out in Portugal shows the difficulties women face in reconciling work with family and personal life. While most studies focus on job satisfaction and women's willingness to work long hours for better career progression, this paper examines gender discrimination at work associated with working time policies. Gender equality and women's empowerment are among the goals set by the 2030 Agenda for Sustainable Development. This study, based on a survey completed by female employees, concludes that women feel discriminated against in their careers due not only to the persistence of gender stereotypes but also to long working hours. Studying women's perceptions of the reasons for discrimination at work, as well as the relationship between working time and equality at work, can be important for understanding the under-representation of women in leadership positions and can help enrich public policies in this area. [ABSTRACT FROM AUTHOR]

Calculation of hidden quality costs has also become important in order to accurately calculate and record quality costs. In research, it trial to calculated the hidden quality costs with the Grey Prediction Method GM (1.1) model and the Taguchi Quality Loss Function, using the data obtained from a business in Denizli that manufactures bagalite parts between the years 2019-2020. In the study, firstly using the grey prediction method GM (1.1) model, the forward prediction of the reclamation expenses, poor quality product costs, internal reprocessing costs, overtime costs and quality training costs were made. Then by making Taguchi Quality Loss application; The loss of quality in the business is examined by considering Taguchi's idea of Loss of Quality and the information obtained from the grey prediction application and the actual costs obtained from the business. Afterwards, the number of quality training and quality training costs in the business were examined according to the years and it was determined whether there was a loss of quality. As a result, in the application of Taguchi Quality Loss detection with Grey prediction method, it was determined that quality loss occurred in poor quality product costs, internal reprocessing costs, quality training costs. It has been determined that there is no loss of quality in the reclamation expenses. It has been tried to show that Taguchi Quality Loss and Quality Loss Function formula can be used not only in certain places but also in every activity and cost calculation. As in the study, original studies should be carried out with different applications. [ABSTRACT FROM AUTHOR]

Contention over COVID-19 is only a recent example of increasing social division around science in the U.S. Many blame these divisions on actors who have strategically sowed doubt and distrust around expert supported positions and policies. However, this overlooks how scientists have fueled narratives of social and political conflict around science. This study explores how science influencers on social media have used group identity language in ways that may perpetuate narratives of intergroup conflict around science. Using computer-assisted content analytic methods, we examine how science influencers' use of group identity language has changed in response to recent events (Trump presidency, COVID-19 pandemic) and across different social media platforms (Twitter, Facebook, Instagram). While there are slight increases in group identity language between 2016 and 2021, different patterns across platforms suggest that science influencers use different platforms to perform multiple roles of engaging diverse audiences, building ingroup solidarity, and defending against outgroup criticism. [ABSTRACT FROM AUTHOR]

The Covid-19 pandemic contributed to an unprecedented expansion of remote work across European countries, transforming what was once a marginal form of work into a new 'normal', particularly in its hybrid form. While bringing advantages for both employers and workers, remote work is also associated with some negative impacts on workers' rights and well-being, including isolation, overtime, stress and difficulties to socialize and organize collectively. This paper explores post-pandemic changes in the regulation of telework in selected European Union (EU) Member States, in an attempt to identify common trends and obstacles in coping with the challenges outlined above. The analysis, attentive to the articulation of different legal sources and regulatory levels, focuses on four areas that are particularly relevant for the regulation of working from home: health and safety; working time; the right to disconnect; and privacy. The five jurisdictions examined - Italy, Spain, France, Luxembourg and Sweden - are representative of different models in the regulation of remote work within the EU. The paper argues that the current regulation of remote work arising from different legal sources and regulatory levels, while offering flexibility to adapt to its specificities, falls short of ensuring a coherent and comprehensive legal framework. This leaves unaddressed some of the challenges raised by the extensive recourse to remote work, giving rise to the need for a more targeted and holistic approach in regulation at different levels. [ABSTRACT FROM AUTHOR]

The stability of money demand is central to South Africa’s monetary policy. Furthermore, it has implications on the work of the SARB which is the monetary authority of South Africa. Since year 2000, the SARB has been hawkish in its behaviour, which raises questions about stability of money demand. This is because for an inflation targeting economy that provides information to the public to stabilize the market, its money demand should be stable, thereby, making the behaviour of the central bank more stable. However, the behaviour of the SARB does not seem to portray that the demand for money in South Africa is stable. Hence, this study assesses the demand for money in order to comprehend its behaviour. The study uses CUSUM test to test for the stability of money demand. And it is found that before year 2015, money demand was stable. Hence, the money demand in South Africa is becoming unstable overtime. The sample data used in the study is from 2003 to 2023. [ABSTRACT FROM AUTHOR]

Education holds significant implications for individual health. This work aims to examine the relationship between educational attainment, lifestyle, self-rated health, and depressive symptoms among Chinese adults. We used China Family Panel Studies data from 2012 to 2020. Multiple linear regression models were used to explore the relationship between educational attainment and self-rated health and depressive symptoms, where multidimensional lifestyle (sleep time, exercise time, overtime time, leisure time, housework time, and protein intake) was the mediator variable of the above relationship, and the causal step method was used to test the mediating effect. Our findings show that educational attainment is associated with higher levels of self-rated health and lower levels of depressive symptoms. More importantly, educational attainment also indirectly affects individuals’ self-rated health and depressive symptoms through lifestyle. These findings reveal health interventions to develop education further and improve its quality.

Orientation: Workplace fatigue has harmed the working environment, with workers becoming increasingly exhausted, disgruntled and detached from their work and co-workers. Curbing workplace fatigue is important to increase job performance, commitment, satisfaction and safety in the work environment. Research purpose: The objective of the study was to investigate the impact of fatigue on the relationship between overtime, burnout, commitment and engagement among South African blue-collar workers. The study also aims to understand the mediating role burnout and engagement play in the relationship model. Motivation of the study: The motivation behind this study was to understand the role fatigue plays in the working life of blue-collar workers. Research approach/design and method: A quantitative, non-experimental, cross-sectional study explored the relationship between overtime, burnout, engagement and commitment among blue-collar workers in South Africa. Data from 381 participants were gathered using purposive sampling. Main findings: The study found negative links between burnout, work engagement, and fatigue, showing that burnout or low engagement increases fatigue. Burnout and fatigue both reduce work commitment, weakening dedication to work. Practical/managerial implications: Reducing fatigue in blue-collar workers may lower burnout and increase commitment, engagement, and overtime willingness. Addressing burnout and promoting engagement is key to minimising fatigue’s negative impact on organisational outcomes. Contribution/value-add: The study contributed to deeper insight into the effect fatigue and burnout have on the blue-collar sample’s work commitment, work engagement and willingness to work overtime.

This paper studies an industrial lot-sizing and scheduling problem coming from the food-industry that extends the multi-item capacitated lot-sizing and includes lost sales, overtimes, safety stock and non-uniform sequence-dependent setups on parallel machines. We introduce two different formulations and adapt the well-known Relax-and-Fix and Fix-and-Optimise heuristics in order to quickly obtain feasible solutions on large industrial instances. The complexity of our problem prevents the procedure to obtain good solutions within the time allocated by practitioners on real-life cases, hence we propose to use a clustering approach to approximate the sequence-dependent setup times. The resulting problem is significantly smaller to solve and experimental results suggest that this transformation effectively improves the solutions found on industrial instances. In particular, the combination of this clustering method and Relax-and-Fix and Fix-and-Optimise procedure turns out to be a promising approach to obtain good solutions in the given time-limit. [ABSTRACT FROM AUTHOR]

This research focuses on the dynamic landscape of today’s competitive market, where production management must meet clients’ expectations for high-quality products and shorter lead times while managing internal disruptions due to inevitable defects and unpredictable equipment failures. Achieving these operational goals without compromising product quality, missing deadlines, or experiencing production disruptions is essential for minimizing operational expenses. The study examines the dynamics of the system’s operating costs through the development of models, mathematical formulations, optimization techniques, and algorithm proposals. It demonstrates the system’s convexity and establishes the optimal batch time for implementing the proposed methodologies. The research results show relevant failure costs of 3.51 %, overtime added costs of 4.57 %, outsourcing setup costs of 0.73 %, outsourcing variable costs of 41.82 %, quality-related costs of 2.98 %, in-house variable costs of 40.42 %, and in-house holding costs of 3.55 %. The study develops strategies for optimal overtime use to meet production targets without excessive labor costs and provides a structured framework for making informed outsourcing decisions that balance cost savings with quality and reliability considerations. Overall, the research provides a robust framework for reducing operational costs while maintaining or improving the quality and reliability of manufacturing processes [ABSTRACT FROM AUTHOR]

Background: Transcatheter aortic valve implantation (TAVI) is a well-established treatment for high and intermediate-risk patients with severe aortic stenosis (AS). Recent studies have demonstrated non-inferiority of TAVI compared to surgery in low-risk patients. In the past decade, numerous literature reviews (SLRs) have assessed the use of TAVI in different risk groups. This is the first attempt to provide an overview of SRs (OoSRs) focusing on secondary studies reporting clinical outcomes/process indicators. This research aims to summarize the findings of extant literature on the performance of TAVI over time. Methods: A literature search took place from inception to April 2024. We searched MEDLINE and the Cochrane Library for SLRs. SLRs reporting at least one review of clinical indicators were included. Subsequently, a two-step inclusion process was conducted: [1] screening based on title and abstracts and [2] screening based on full-text papers. Relevant data were extracted and the quality of the reviews was assessed. Results: We included 33 SLRs with different risks assessed via the Society of Thoracic Surgeons (STS) score. Mortality rates were comparable between TAVI and Surgical Aortic Valve Replacement (SAVR) groups. TAVI is associated with lower rates of major bleeding, acute kidney injury (AKI) incidence, and new-onset atrial fibrillation. Vascular complications, pacemaker implantation, and residual aortic regurgitation were more frequent in TAVI patients. Conclusion: This study summarizes TAVI performance findings over a decade, revealing a shift to include both high and low-risk patients since 2020. Overall, TAVI continues to evolve, emphasizing improved outcomes, broader indications, and addressing challenges. [ABSTRACT FROM AUTHOR]

This article advances the literature on the spatial patterns of EU support by arguing that the relationship between regional inequality and EU trust is not linear. We posit that, to fully understand this relationship, we should systematically investigate three dimensions of regional inequality, i.e., regional wealth status, regional wealth growth, and regional wealth growth at different levels of wealth status. Using individual-level survey data for EU27 countries and the UK from 11 Eurobarometer waves (2015–2019), we show that a non-linear association exists whereby poor and rich European regions tend to trust the EU more compared to middle-income regions, and that within-region over-time growth is associated with higher levels of EU trust. We demonstrate that the association between growth and EU trust is more pronounced among poor and middle-income regions compared to rich regions. Our findings have implications about the nature of public Euroscepticism and the ways in which to address it. [ABSTRACT FROM AUTHOR]

The unprecedented power of Big Tech corporations and the complexity of regulating them requires considering the role of news media as a corporate accountability mechanism. The aim of this article is to examine news media's watchdog role through a performative lens, extending it to the corporate context by looking at three manifestations of performance: media visibility, way of coverage, and sourcing patterns. Based on a longitudinal quantitative content analysis of 920 news stories on Big Tech from four media outlets (2000–2021) in the United States and Germany, we explain variances in the watchdog role taking an over-time, cross-country, and cross-political leaning perspective. Our findings suggest that Big Tech corporations receive little but increasing media attention over the years that is driven by events. Similarly, news coverage contains an increasingly strong presence of a detached watchdog role performance. A more interventionist watchdog role is also on the rise – even though marginally – and political actors are increasingly given a voice in news coverage. From a comparative perspective, our results show that Big Tech corporations are more visible in the US and across right leaning news outlets. US journalists exhibit a more detached approach, while German journalists perform a significantly higher interventionist performance. Corporate sources are overall prominent in the media arena yet dominate more in the US. In conclusion, US and German news media are critical but passive observers over Big Tech corporations and can therefore be labeled a tame yet increasingly growling watchdog when it comes to holding Big Tech accountable. [ABSTRACT FROM AUTHOR]

Supportive measures for employees raising children may have increased workloads on other nurses, causing psychological stress. This study aimed to clarify the differences in working conditions and psychological status among female Japanese nurses based on child-rearing attributes. We used data from 1,600 female nurses at 10 Japanese hospitals collected by the study of the Work Environment for Hospital Nurses in Japan conducted in 2016. The variables included work conditions (number of night shifts per month, daily overtime, number of paid holidays per year, and social support received), psychological status (sense of coherence, emotional exhaustion, and work engagement), and sociodemographic characteristics. An analysis of covariance was performed on the differences between the three groups (without children, with preschool-age children, and with children of other ages groups). The group without children had a relatively higher workload (p<0.01) and lower social support (p<0.01 and p<0.05). Additionally, they had higher emotional exhaustion and lower work engagement (p<0.01). This study confirmed the uneven distribution of work environment by work-life balance measures. [ABSTRACT FROM AUTHOR]

This paper critically examines the notion of working time flexibility of platform takeaway riders and its impact on them in China. Drawing on 25 interviews with platform and takeaway delivery company managers and takeaway riders as well as secondary data, the study finds that the management model adopted by the platform companies and their agency companies often encourages riders to extend their working hours by being designed into the rider's earning system, status level and various incentive schemes. Driven by profits, takeaway delivery platform companies pursue speed and impose harsh punishments for poor customer reviews. Severe competition and the platforms' aggressive pricing and commissioning practices mean that takeaway riders' remuneration is tightly squeezed, with no subsidies or overtime payment, and with rules for bonuses that make it increasingly difficult to earn. Working excessively long and intense hours is the only way that riders can increase their income, which suggests that rider-oriented working time flexibility is virtually non-existent. We propose the notion of fragmented employment relationships and fragmented working time to conceptualise working time flexibility in the takeaway delivery context in China. We accentuate the need to examine the quality of working time flexibility when examining this practice. We call for state interventions to provide a greater level of social protection than the takeaway riders are currently experiencing to advance the decent work agenda as part of the Sustainable Development Goals. [ABSTRACT FROM AUTHOR]

Overtime, choosing not to have children has become a more common phenomenon. Alongside this change, studies have found that women without children are just as fulfilled, if not more so, in their lives as those who have had children. These studies, in the context of theories of second-wave feminism, psychosocial theory, and stigma theory, are reviewed. This study presents a dissatisfied older woman who has not had children to examine the differences in such cases. As a product of thematic analysis, five themes stand out during Holly's interview: focus on the past, stigma, fear, relationships with younger generations, and regret. Results are discussed in the context of what they may mean for future research and practice with the suggestion that perhaps an over-focus on the past, in lieu of present and future circumstances, may be a factor in childless women's dissatisfaction in life. [ABSTRACT FROM AUTHOR]