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Seleno-Yeasts (SY) used as feed additives are known to contain different Selenium (Se) species. Seleno-Yeasts has been shown, on previous analytical methods, to contain selenomethionine (SeMet), selenocysteine (SeCys), selenate (SeIV) and selenite (SeVI), and various other organic and inorganic Se forms identified but rarely quantified. A new advanced method has allowed elemental Se (Se0), an inorganic Se species, to be quantified, thereby obtaining better insight into the proportion of inorganic Se in SY products. The study aimed to quantify the Se0 in SY products and assess the proportion of inorganic Se in SY. The Se speciation of 13 fresh commercials SY from different suppliers and batches, was assayed for the total Se, inorganic Se species (SeIV, SeVI and Se0), and organic Se species (SeMet and SeCys). Results on total Se were in line with the expected Se concentrations for all evaluated samples. The proportion of Se present as Se0 ranged from 3.6% to 51.8%. The quantity of Se0 in the SY products, added to SeIV and SeVI, indicated an average proportion of inorganic Se of 14.2% for the 13 analyzed SY products. The proportion of Se as SeMet ranged from 19.0% to 71.8%, (average of 55.8%), and a large variability in the SeMet content was observed. The SeCys content was also variable, with an average of 3.8%, relative to the total Se. In conclusion, advances in the analytical characterization have revealed that SY products can have a significantly high proportion of inorganic Se, which could affect the bioavailability of Se from SY supplements and explain their variable and lower bio-efficacy than pure SeMet supplements, such as hydroxy-selenomethionine. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Agro-Environment Science is the property of Journal of Agro-Environment Science Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Selenium pollution in water is a worldwide issue. Se(IV) and Se(VI) are mainly found in contaminated water due to their high solubility and mobility; their presence poses a serious risk as they can severely harm human health. Although iron oxide and hydroxide nanoparticles can be efficient candidates for the removal of selenium oxyanions due to their high adsorption capacity, the role of each iron species has not been fully elucidated. Furthermore, iron species are often found to be less effective for Se(VI) than Se(IV). The challenge and novelty of this study was to develop a carbon material impregnated with different iron phases, including oxides (magnetite/hematite) and hydroxides (goethite/lepidocrocite) capable of removing both Se(IV) and Se(VI). Since the phase and morphology of the iron nanoparticles play a significant role in Se adsorption, the study evaluated both characteristics by modifying the impregnation method, which is based on an oxidative hydrolysis with FeSO4 7H2O and CH3COONa, and the type of carbonaceous support (activated carbon or sucrose-based carbon foam). Impregnated activated carbons provide better removal efficiencies (70–80%) than carbon foams (<40%), due to their high surface areas and point zero charges. These results show that the adsorption of Se(VI) is more favorable on magnetic oxides (78%) and hydroxides (71%) than in hematite (<40%). In addition, the activated carbon decorated with magnetite showed a high adsorption capacity for both selenium species, even in alkaline conditions, when the sorbent surface is negatively charged. A mechanism based on the adsorption of inner-sphere complexes was suggested for Se(IV) immobilization, whereas Se(VI) removal occurred through the formation of outer-sphere complexes and redox processes. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Hydrobiology is the property of Editorial Department of Journal of Hydrobiology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Previous studies indicated that the antioxidant and water balance capacity played important roles in improving the vase life of cut flowers. As a trace element, selenium (Se) has been proven to play an important role in extending the vase life of lily cut flowers. However, there is still no report on the effects of Se on the vase life of other cut flowers. In this study, we explored the role of inorganic selenium, named sodium selenite (Na2SeO3), in improving the vase life of Eustoma grandiflorum cut flowers. Compared with the control (distilled water) and the other Na2SeO3 concentrations, 4.0 mg/L Na2SeO3 significantly increased the superoxide dismutase, catalase, ascorbate peroxidase glutathione reductase, glutathione peroxidase and glutathione S-transferase activities, and decreased the malondialdehyde content and the electrolyte leakage. Meanwhile, compared with the control and the other of Na2SeO3 concentrations, 4.0 mg/L Na2SeO3 significantly increased the soluble sugar, proline and soluble protein contents, relative water content, average fresh weight change rate and average water balance value. The above results imply that Na2SeO3 showed an important role in strengthening the antioxidant capacity and maintaining the water balance. Besides, 4.0 mg/L Na2SeO3 significantly increased the flower diameter and the vase life. The above findings suggested that Na2SeO3 extended the vase life and the ornamental value of E. grandiflorum cut flowers by enhancing the antioxidant capacity and water balance, which provides new knowledge for the application of Na2SeO3 in improving the fresh keeping of E. grandiflorum cut flowers.

Selenium is an essential microelement involved in various biological processes. Selenium deficiency increases the risk of human immunodeficiency virus infection, cancer, cardiovascular disease, and inflammatory bowel disease. Selenium possesses anti-oxidant, anti-cancer, immunomodulatory, hypoglycemic, and intestinal microbiota-regulating properties. The non-linear dose-response relationship between selenium status and health effects is U-shaped; individuals with low baseline selenium levels may benefit from supplementation, whereas those with acceptable or high selenium levels may face possible health hazards. Selenium supplementation is beneficial in various populations and conditions; however, given its small safety window, the safety of selenium supplementation is still a subject of debate. This review summarizes the current understanding of the health-promoting effects of selenium on the human body, the dietary reference intake, and evidence of the association between selenium deficiency and disease.

This study was aimed to investigate the effect of in-ovo injection with vitamin E and selenium during the incubation and post-hatching period. 360 fertilized eggs of Ross 308 broiler breeders were incubated, then distributed on 10th day into three groups (120 eggs/group). 1st group: uninjected eggs, 2nd group: eggs were injected with 0.1 ml deionized water/egg in the chorioallantoic cavity, and 3rd group: eggs were injected with 0.1 ml/egg of Introvit-E-Selen in chorioallantoic cavity. After hatching, 270 chicks were randomly distributed into six groups, and reared until 42 days aged as follows: birds in 1st, 3rd and 5th groups drinks tap water only (free from any addition), while birds of other groups, were reared on drinking water supplemented with 12.5 mg vitamin E and 500 µg sodium selenite/liter water. Results showed a significant increase in hemoglobin, lymphocytes% and serum globulin, and a significant decrease in packed cell volume%, heterophils%, heterophils/lymphocytes ratio, glucose, cholesterol, triglycerides and albumin concentration as compared with control. In conclusion, vitamin E and selenium have enhanced some immunological aspects and reduced stress, as well as a number of hematological parameters of broiler chicks, also, the continuity of Vit.E)Selenium addition led to continuous improvement of physiological parameters, and when it stopped, the values of those parameters were retracted [ABSTRACT FROM AUTHOR]

Flavonoids from Ginkgo biloba have antioxidant and free radical scavenging activity. In the present study, we used different concentrations of OS (organic selenium), NS (nano-selenium), and IS (inorganic selenium) to treat the 2-year-old Ginkgo seedlings and studied the effects of different concentrations of selenium treatment on the physiological indexes and flavonoid content of Ginkgo at different growth stages. Our results showed that the content of chlorophyll, soluble sugar, and total flavonoid glycosides in the 1.6-mM NS treatment group increased significantly in July and September (by 43.87%, 59.92%, and 43.99% and 13.86%, 18.60%, and 35.04%), compared to the control respectively, all P < 0.05. To further analyze the changes of flavonoid content and gene expression levels in Ginkgo leaves, transcriptome sequencing analysis was performed on the treated seedlings. Sequencing analysis results showed that NS could promote PAL, COMT, CAD, and F6H gene expression levels in the flavonoid synthesis pathway; OS up-regulates the CCR and HCT genes. IS promotes the expression of C3'H, CCoAOMT, CYP, DFR, and HCT genes. Furthermore, the increase of key genes and enzyme levels promotes the increase of total flavonoid content. These data suggest that the appropriate concentration of OS and NS can promote the expression level of flavonoid synthesis genes and further promote the increase of total flavonoid content in Ginkgo leaves, which is beneficial to the medicinal value of Ginkgo extract. [ABSTRACT FROM AUTHOR]

[Display omitted] • Garlic Se absorption and transportation were largely affected by Se speciation. • Organic Se was superior to inorganic Se in enriching Se and antagonizing Cd. • Bulb Se content treated with organic Se was about twice (or more) than inorganic Se. • Organic Se was significantly more effective in reducing Cd content than inorganic Se. • Se was mainly enriched in bulb, Cd was enriched in root under organic Se application. Currently, planting selenium-rich crops using inorganic selenium such as selenate and selenite is used to address human selenium deficiency problems. In this paper, besides the above two traditional inorganic selenium speciation, we chose a new organic selenium speciation of potassium selenocyanoacetate to investigate the different effects of selenium speciation on selenium absorption, selenium transformation and cadmium antagonism via foliar application. Planting experiments showed that the selenium content of garlic bulbs treated with organic selenium was 1.8–3.9 times higher than that of inorganic selenium. Additionally, the absorption and transformation efficiency of organic selenium in garlic was also the highest, reaching over 95 %. Importantly, it was noteworthy that the cadmium content in bulbs treated with organic selenium was significantly lower than the Chinese food safety standard (0.2 mg/kg). Hence, this study provides an efficient organic selenium speciation which is beneficial to meet human selenium requirements and ensure safe utilization of cadmium-contaminated soils. [ABSTRACT FROM AUTHOR]

This study aims to investigate the effects of different selenium (Se) sources on the growth performance of Chinese broilers and provide a scientific rationale for adding Se additives to broiler feed. Relevant studies that meet standard inclusion criteria were identified and extracted from China National Knowledge Infrastructure and Wanfang and Chinese Scientific Journal (VIP) databases. A total of 9 studies with 539 subjects were included. A meta-analysis was performed with STATA15.0 to estimate the combined standardized mean difference (SMD) with a 95% confidence interval (95% CI). Heterogeneity test of articles was examined by Q-test, and the results showed that P values of feed conversion ratio, average daily gain (ADG), and average daily intake were all less than 0.05, suggesting a strong heterogeneity among the selected literature. Therefore, the random effect model is selected to calculate the SMD of the three indexes. The combined SMDs (95% CI) of feed:gain, ADG, and average daily feed intake (ADFI) were −0.39 (−1.03, 0.25), 0.26 (−0.29, 0.81), and −1.45 (−3.09, 0.20), respectively, and the P values were all less than 0.05. This study shows that the absolute differences in the growth performance (feed:gain, ADG, and ADFI) of broilers fed with either organic or inorganic Se supplements at the same dose were quite small. The P values of Egger’s test were 0.770, 0.089, and 0.426, respectively, for the above indexes, showing no significant publication bias. Sensitivity analysis ensured the stability and reliability of the results. In summary, the effects of organic and inorganic Se in feed on the growth performance of broilers are statistically equal.

Abstract The chemical properties including toxicity of selenium depend on the concentration and chemical structure present in the natural environment. Inorganic selenium is more toxic than organic selenium; thus, the accurate determination of inorganic selenium in various sample has been needed. HG-AAS, HPLC-ICP-MS, and GC-MS are the current methods for the determination of inorganic selenium. However, these methods have the disadvantage of expensive equipment, complicated sample preparation, and long analysis time. LIBS coupled with ion exchange membrane was used for the determination of inorganic selenium. The detection limit of inorganic selenium by the analytical method was 11.21 mg/kg, and the recoveries of 50 and 100 mg/kg Se(VI) were 98.5 % and 101.80 %, respectively. The speciation method is cost-effective, simple, and not labor intensive for the quantitation of inorganic selenium.

The total selenium content of selenium-enriched agricultural products was determined by inductively coupled plasma mass spectrometry after microwave digestion. The total selenium content in the tested samples ranged from 27.9 μg/kg to 13.6 mg/kg. High performance liquid chromatography–inductively coupled plasma mass spectrometry was employed to determine selenite and selenate in selenium-enriched rice, tea, and garlic. The separation of inorganic and organic selenium was realized within 15 min by using 40 mmol/L diammonium phosphate (pH 5.0) and 60 mmol/L diammonium phosphate (pH 6.0) as the mobile phase with gradient elution. Selenite and selenate were isolated by ultrasonic assisted extraction at 78 °C for 30 min with 0.1 mol/L potassium hydroxide as the extraction solution. The detection limits were 2.5 and 5 μg/kg for selenite and selenate, respectively. The relative standard deviation was less than 5.5%. Recoveries of inorganic selenium were between 88.2% and 113.0%. The proposed method was successfully applied for the determination of inorganic selenium as well as total selenium in selenium-enriched rice, tea, and garlic. The results showed that inorganic selenium in natural selenium-enriched agricultural products is primarily present in selenite composing no more than 20% of total selenium. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Asian Journals of Ecotoxicology is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

[Display omitted] • A 2,3-diaminonaphthalene post-synthetic modified magnetic MOF was fabricated. • The material was applied to the selective extraction of inorganic selenium. • The material exhibited selectivity toward Se(IV) at a pH of 2.5. • LOD and linear range were 8.0 ng/L and 25–8000 ng/L, respectively. • The analytical applicability was confirmed in various food, and water samples. In this work, a 2,3-diaminonaphthalene post-synthetic modified magnetic metal–organic framework was fabricated for fast and selective determination of inorganic selenium in real food and water samples. The results exhibited that selenium (IV) is adsorbed by the nano-material at a pH of 2.5, and in this way, selenium (IV) can be quantified selectively. After identifying the nanosorbent with FT-IR, CHNS, XRD, SEM, TEM, VSM, and BET surface analysis, parameters affecting the retention and desorption were optimized. Under optimal conditions, the detection limit of 8 ng/L was achieved for selenium (IV), and the method's precisions were less than 12.5 % intra-day RSD% and < 14.4 % for inter-day RSD%. The highest adsorption capacity was obtained as 264 mg/g. Finally, the desired adsorbent was used to extract and determine selenium species in water samples and total selenium in food samples. One of the most important advantages of the present method is its speed, ease, time-saving, and high accuracy. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Inorganic Analytical Chemistry / Zhongguo Wuji Fenxi Huaxue is the property of Beijing Research Institute of Mining & Metallurgy Technology Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Cadmium (Cd) is an element injurious for human health and is possibly toxic to organisms at minor concentrations. While some of other trace metallic elements have antagonistic features to it. One of them is the interaction between selenium (Se) and Cd in plant different organs. Literature review disclosed that the intake of Se to some extent can reduce the accumulation of Cd in plants, while the research on of trace metallic elements (Cd) and Se-enriched food (rice) in the living body has rarely been reported. This study intended to explore whether there was a mitigating effect of Se-enriched rice on mice poisoned with Cd. A mouse model of low-dose and high-dose Cd poisoning was established (supplemented with cadmium chloride(CdCl2·2½H20)), followed by feeding two groups (1) Se-enriched rice and (2) setting an equal amount of inorganic Se group. After that, the impact of Se-enriched rice on the antioxidant activity was evaluated. The Se-enriched diet enhanced the total antioxidant capacity (T-AOC), superoxide dismutase (SOD), and enzyme activities of GSH peroxidase (GSH-Px) in mice livers and kidney whereas significantly decreased the malondialdehyde (MDA) contents. Moreover, the degree of physiological damage in mice with low cadmium poisoning was significantly alleviated, and the expression of antioxidant genes (Nrf-2, GPX1, TrxR2, TNF-2) was increased. In conclusion, the Se-enriched diet has a positive effect on the biological effects in mice, and it can be used as a daily diet to resist damage to the body's low Cd state and support enzymatic antioxidant systems by eliminating oxidative injury. [ABSTRACT FROM AUTHOR]

The chemical properties including toxicity of selenium depend on the concentration and chemical structure present in the natural environment. Inorganic selenium is more toxic than organic selenium; thus, the accurate determination of inorganic selenium in various sample has been needed. HG-AAS, HPLC-ICP-MS, and GC-MS are the current methods for the determination of inorganic selenium. However, these methods have the disadvantage of expensive equipment, complicated sample preparation, and long analysis time. LIBS coupled with ion exchange membrane was used for the determination of inorganic selenium. The detection limit of inorganic selenium by the analytical method was 11.21 mg/kg, and the recoveries of 50 and 100 mg/kg Se(VI) were 98.5 % and 101.80 %, respectively. The speciation method is cost-effective, simple, and not labor intensive for the quantitation of inorganic selenium. [ABSTRACT FROM AUTHOR]

The aim of the present study was to assess the effects of selenium feed supplements on the functional properties of eggs. The hens in experimental groups were fed diets supplemented with 0.2 mg/kg selenium from sodium selenite (Group 1), selenium-enriched yeast (Group 2), synthetic L-selenomethionine (Group 3), or hydroxy analog of selenomethionine (Group 4). The Control Group (Group C) was fed with basal feed without supplementation. The highest values of albumen gel firmness were shown in Group C eggs; differences with all experimental groups were significant (p < 0.001 to p = 0.009). It was ascertained that albumen gel firmness correlated with albumen pH (rs = 0.490; p < 0.001), which was highest in eggs from non-supplemented hens. Group 1 eggs and Group C eggs showed lower albumen foaming capacity (p < 0.001) compared to eggs from other groups. Both albumen foaming capacity and albumen foam stability were higher in Group 2 eggs than in Group C eggs (p < 0.001). The highest yolk foaming capacity was found in Group 2 eggs (p < 0.001). Sponge cakes baked with Group C eggs had a smaller volume than those baked with eggs from Group 2 (p = 0.005), Group 3 (p = 0.004) and Group 4 (p = 0.024). The results of the study confirmed that selenium added to the laying hen feed significantly affected the monitored functional properties of both albumen and yolk. The most distinctive effect of selenium was shown in eggs from the group supplemented with selenium-enriched yeast, for which the results of albumen foam capacity and stability and yolk foaming capacity were the best. [ABSTRACT FROM AUTHOR]

Copyright of Alexandria Journal of Food Science & Technology is the property of Egyptian National Agricultural Library (ENAL) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Accurately quantifying selenium (Se) speciation and transformation in Se-enriched crops is highly significant for human health. The investigation of Se species in Se-enriched crops involves assessing the enrichment of both organic and inorganic Se species, considering their plant families and edible parts. The staple crops of rice, corn, and wheat showed no or less inorganic Se with the increase of total Se; however, potatoes expressed a proportion of selenate [Se(VI)]. In addition, the organic Se proportions in Se-enriched crops of Cruciferous, Brassicaceae , and Umbelliferae plant families were relatively lower than the proportion of inorganic Se. Concurrently, the edible parts of the Se-enriched gramineous or cereal crops enriched with organic Se and crops with fruit, stem, leaf, and root as edible parts contain the maximum percentage of organic Se with a certain proportion of inorganic Se. This study contributes to a sparse body of literature by meticulously discerning appropriate Se-enriched crop selection through a comprehensive evaluation of Se speciation and its organic and inorganic accumulation potential.

This study aimed to evaluate effects of supplementing the diets of laying hens with different sources of Se and different levels of flaxseed on egg Se concentration, yolk antioxidant properties and immune response. In a completely randomized design, 384 Hy-Line W-36 hens (aged 50 weeks) were assigned to a 3 × 4 factorial arrangement, comprising four replicates of eight hens. For 10 weeks, the birds were fed one of three basal diets containing 0, 50, and 100 g/kg of flaxseed and regular Se content from mineral premix, supplemented with no additional Se (SN) and 1 mg/kg of Se from sodium selenite (SS), Se-enriched yeast (SY), and hydroxy selenomethionine (SOH). The greatest Se concentration in the yolk was observed in diets containing organic Se sources. The SOH diet produced the greatest albumen Se concentration, followed by SY, and then SS. Using any Se supplementation improved glutathione peroxidase activity and total antioxidant capacity, compared with SN. However, superoxide dismutase activity and malondialdehyde were not affected by Se supplementation. Cell-mediated immune response was improved by Se supplementation, especially SS. Antibody response against sheep red blood cell (SRBC) was not affected by Se source, except that IgM was greater in the hens that received SS and SY. Neither flaxseed supplementation, nor its interaction with Se source was significant for any trait. Thus, supplementation of diets with 1 mg/kg Se, especially from organic sources, enriched the egg and improved some yolk antioxidant properties and immune system function. Supplemental flaxseed did not influence any measured traits. [ABSTRACT FROM AUTHOR]

• Lactic acid bacteria convert sodium selenite into organic selenocysteine and elemental Nano-selenium. • Lactic acid bacteria were selected on their ability to grow in a sodium selenite medium and to convert selenite to organic and Nano-Se. • The ability of lactic acid bacteria to act as silage inoculants was not compromised by the addition of sodium selenite. • Lactic acid bacteria inoculants can convert sodium selenite in silo to supplement livestock with organic and predominately Nano-Se. Selenium (Se) is a non-metallic trace element essential for normal cellular function, which has been linked with reduced risk of cancer, cardiovascular disease, cognitive decline and thyroid disease in humans. Se deficiency in livestock is associated with white muscle disease, retained placenta, ill-thrift and mastitis. Where Se status or bioavailability from the soil for plants is poor, livestock rely on supplemental Se in their diets predominantly as either sodium selenite (inorganic form) or selenised-yeast (organic form). As lactic acid bacteria (LAB) have been shown to incorporate Se as either organic or elemental (Nano-Se) there may be potential to use silage inoculant bacteria to improve the Se status of feed to provide the Se requirements of livestock. We screened twenty-seven LAB in MRS broth in the presence of sodium selenite for growth and uptake of Se as organic (selenocysteine and selenomethionine), inorganic (selenite and selenate) or/and Nano-Se, with the aim to identify potential candidates for a mini-silo study. Sodium selenite addition into the growth medium of LAB reduced growth rates but also resulted in the conversion of the inorganic sodium selenite into predominately Nano-Se and small quantities of organic-Se. Based on a rank analysis of growth and ability to take up (total Se content) and convert inorganic Se (Nano and organic Se content), three LAB were selected for further investigation as silage inoculants: L. brevis DSMZ (A), L. plantarum LF1 (B), and L. plantarum SSL MC15 (C). Each LAB was used as an inoculant within a grass mini-silo trial, either cultured in the presence of sodium selenite before inoculation or sodium selenite added to the inoculum at inoculation versus controls with no Se. The addition of sodium selenite either into the growth media of LAB or applied at inoculation of grass silage did not interfere with the ability of the LAB to act as a silage inoculant with no difference in silage fermentation characteristic between LAB with no Se added. The addition of sodium selenite either to the LAB growth medium or at inoculation resulted in the conversion of sodium selenite into Nano-Se and organic-Se (Nano-Se, ca. 103 higher than organic), as previously shown in the screening trial. There was no difference between the three LAB for incorporation of Se or in silage quality, indicating the potential to develop silage inoculants to increase the bioavailable form of Se (elemental and organic) to livestock through conversion of inorganic forms during ensiling. [ABSTRACT FROM AUTHOR]

BACKGROUND: Selenium is an indispensable trace element for humans and its deficiency can lead to serious health complications. Nearly 70% of the area of China faces selenium deficiency. To deal with this problem, selenium‐enriched rice has been increasingly incorporated into everyday diets. However, there is a lack of in‐depth studies of the absorption, translocation, and transformation of selenium in the different parts of the rice plant when sprayed with sodium selenite. RESULTS: Foliar sodium selenite applied at critical growth stages can significantly improve the total and organic selenium content of plants. Application of 10 mg L−1 sodium selenite led to the most organic selenium (0.03 mg kg−1) in polished rice. Correlation studies of sodium selenite applied to leaves and other plant parts showed that total selenium accumulated most in glume, followed by rice bran, then polished rice, and finally embryo. The behavior of organic selenium was different. Organic selenium accumulated most in polished rice, then embryo, then rice bran, and finally glume. Moreover, 75–85% of the Se found in polished rice and embryo was organic in nature. CONCLUSIONS: We propose that 10 mg L−1 sodium selenite can be recommended as appropriate for foliar fertilization in the organic selenium biofortification of Se‐free rice. © 2018 Society of Chemical Industry [ABSTRACT FROM AUTHOR]

The present study amid to evaluate the effect of feeding Silver Montazah parents reared in open system house during winter season on different selenium sources and levels on the fertility of cocks, performance and mortality % of hatched chicks. The examined two selenium sources were nano selenium (Nano-Se) and sodium selenite (SS), and the three supplemental levels of each source were 0.10, 0.25 and 0.40 ppm. 180 females and 90 males of Silver Montazah chickens divided into 6 treatments of three replicates of each. Males and females located in separate battery cages in open system house. Semen characterization was carried out, then hens were artificially inseminated by semen from cocks with the same dietary treatment. A total number of 90 eggs/treatment were incubated and fertility and hatchability were calculated. Hatched chicks fed on control diet containing 0.10 mg SS /kg diet up to 2 wks of age then chicks of each treatment received the same Se treatments of their parents. Growth performance of chicks was recorded up to 8 wks of age. The obtained Results showed that: - Using Nano Se improved semen ejaculate volume, sperm motility, growth performance of hatched chicks during first 2 wks of age and their dressing % and PCV% at 8 wks of age, also it improve significant the activities of antioxidant system and liver functions. , using levels 0.25 mg Se/kg enhance the overall semen quality, fertility and hatchability chick performance and their physiological statues. - The overall results of all experiment treatments showed superior effect of using Nano-Se at level 0.25 mg Se /kg diet to enhance the overall reproductive performance of cocks and growth and physiological status of their hatched chicks up to 8 wks. In addition, the examination of blood cells and plasma biochemical measurements showed positive effect on antioxidant system and overall immune status. Based on the obtained results we could recommend using 0.25 mg Nano Se/kg diet to enhance the reproductive performance of Silver Montazah cocks and decrease mortality rate of growing chicks during winter season. [ABSTRACT FROM AUTHOR]

Ninety-six male goslings were allocated and assigned to treatment using a completely randomized design. Dietary treatments included a basal diet consisting of corn, wheat, and soybean meal with either no additional selenium (CON), 0.3 mg/kg of inorganic selenium (I-Se; sodium selenite), or 0.3 mg/kg of organic selenium (O-Se; selenium-enriched yeast). After a 56-day feeding period, geese were slaughtered on a common ending day and two geese per pen (n = 24) were used for the analyses conducted in this study. Meat (equal portions of the breast and thigh meat) and liver were collected and evaluated for proximate composition, fatty acid profile, pH, phenolic content, thiobarbituric acid reactive substances (TBARS), and total volatile basic nitrogen (TVB-N) over a 9-day storage period at 4 °C. The meat and liver samples from geese supplemented I-Se or O-Se had greater (p < 0.01) lipid content compared with geese not supplemented with additional selenium. At the conclusion of the 9-day storage period, meat and liver samples from geese supplemented I-Se or O-Se had lower (p < 0.05) pH values, greater (p < 0.05) phenolic content, lower (p < 0.05) TBARS values, and lower (p < 0.05) TVB-N compared with geese not supplemented with additional selenium (CON).

The aim of the study was to compare the effect of selenium (Se) supplementation in organic (lactate-protein complex) or inorganic (sodium selenite) forms on Se concentrations in the blood and organs of goat kids. The experiment involved nineteen male goat kids divided into three groups: C, Se-I, and Se-O. Control group C (n = 5) was without Se supplementation, group Se-I (n = 7) received sodium selenite supplement (0.30 mg Se per animal/day), and group Se-O (n = 7) received lactate-protein selenium complex (0.28 mg Se per animal/day). The supplementation started on the day of weaning and continued for 13 weeks till the day of slaughter. Blood samples for determination of Se concentration and glutathione peroxidase activity were collected on the day of weaning and during weeks 4, 8, and 13 thereafter. Samples of liver tissue, spleen, kidneys, lungs, heart, tongue, diaphragm, shoulder, back, and thigh muscles were taken immediately after slaughter. Significantly higher concentration of Se in group Se-O in comparison with group C was found in thigh muscles (110.4 vs 71.0 µg/kg, P ≤ 0.01), shoulder (105.0 vs 67.2 µg/kg, P ≤ 0.01), back (102.9 vs 61.7 µg/kg, P ≤ 0.01), and heart (180.8 vs 116.7 µg/kg, P ≤ 0.01). Significantly higher concentration of Se in group Se-I in comparison with group C was found in shoulder (83.2 vs 67.2 µg/kg, P ≤ 0.01) and diaphragm (93.6 vs 72.8 µg/kg, P ≤ 0.01). The comparison of the groups Se-I and Se-O showed significantly higher Se concentrations in thigh muscles, heart, back, shoulder, and lungs in group Se-O. Mean Se concentration in tissues of experimental groups was 125.8% in Se-O group and 110.7% in Se-I group in comparison with group C. Our results are suggesting that supplementation of Se in the form of lactate-protein complex is more efficient in comparison with sodium selenite.

The present study aimed to investigate the influence of maternal selenium supplementation on the skeletal muscle development of the offspring. A total of 720 Ross 308 broiler breeders at 24-week-old were allocated into 3 treatments with 6 replicates of 40 hens each and fed with 0 mg/kg-(group Se/C), 0.5 mg/kg organic-(group Se/O), and 0.5 mg/kg inorganic-(group Se/I) selenium, respectively for 8 weeks. The male offspring from each nutritional treatment were divided and housed into 8 cages of 12 birds each and fed with a commercial diet supplemented with selenium from Na2SeO3 at 0.15 mg/kg. Results showed that Se/O group had the highest selenium deposition (P < 0.05) in the egg yolk and albumen. Furthermore, maternal selenium supplementation promoted breast muscle yield; increased serum insulin and IGF-I concentration; upregulated AKT, mammalian target of rapamycin (mTOR), P70S6K, Myf5, MyoD, MyoG, and SelW mRNA levels; and improved the phosphorylation of AKT at Serine 473 residue, mTOR at Serine 2448 residue, and FOXO at Serine 256 residue in skeletal muscles of the offspring. In contrast, the hens’ diet supplemented with selenium could result in reduction of uric acid level in serum and downregulation of Atrogin-1 and MuRF1 mRNA levels in the skeletal muscle of the offspring. Additionally, no significant effect on the skeletal muscle development post-hatch was observed between organic and inorganic selenium supplementation. In conclusion, maternal organic selenium supplementation improved selenium deposition in egg; however, no significant effect has been detected on the breast muscle development of the offspring of broiler breeder compared with inorganic selenium supplementation. [ABSTRACT FROM AUTHOR]

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Selenium is a trace element essential for human health that has received considerable attention due to its nutritional value. Selenium’s bioactivity and toxicity are closely related to its chemical form, and several studies have suggested that the organic form of selenium (i.e., selenomethionine) is more bioavailable and less toxic than its inorganic form (i.e., sodium selenite). Probiotics, especially Bifidobacteriium and Lactobacillus spp., have received increasing attention in recent years, due to their intestinal microbial balancing effects and nutraceutical benefits. Recently, the bioconversion (a.k.a biotransformation) of various bioactive molecules (e.g., minerals, primary and secondary metabolites) using probiotics has been investigated to improve substrate biofunctional properties. However, there have been few reports of inorganic selenium conversion into its organic form using Bifidobacterium and Lactobacillus spp. Here we report that the biosynthesis of organic selenium was accomplished using the whole cell bioconversion of sodium selenite under controlled Bifidobacterium bifidum BGN4 culture conditions. The total amount of organic and inorganic selenium was quantified using an inductively coupled plasma-atomic emission spectrometer (ICP-AES). The selenium species were separated via anion-exchange chromatography and analyzed with inductively coupled plasma-mass spectrometry (ICP-MS). Our findings indicated that the maximum level of organic selenium was 207.5 µg/g in selenium-enriched B. bifidum BGN4. Selenomethionine was the main organic selenium in selenium-enriched B. bifidum BGN4 (169.6 µg/g). Considering that B. bifidum BGN4 is a commercial probiotic strain used in the functional food industry with clinically proven beneficial effects, selenium-enriched B. bifidum BGN4 has the potential to provide dual healthy functions as a daily supplement of selenium and regulator of intestinal bacteria. This is the first report on the production of organic selenium using B. bifidum spp.

Selenium is an essential microelement involved in various biological processes. Selenium deficiency increases the risk of human immunodeficiency virus infection, cancer, cardiovascular disease, and inflammatory bowel disease. Selenium possesses anti-oxidant, anti-cancer, immunomodulatory, hypoglycemic, and intestinal microbiota-regulating properties. The non-linear dose-response relationship between selenium status and health effects is U-shaped; individuals with low baseline selenium levels may benefit from supplementation, whereas those with acceptable or high selenium levels may face possible health hazards. Selenium supplementation is beneficial in various populations and conditions; however, given its small safety window, the safety of selenium supplementation is still a subject of debate. This review summarizes the current understanding of the health-promoting effects of selenium on the human body, the dietary reference intake, and evidence of the association between selenium deficiency and disease., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2023 Sun, Wang, Gong, Yao, Ba and Wang.)

The aim of this study was to determine the effect of higher amount of inorganic selenium (Na2SeO3) on productivity parameters and meat quality of pigs for fattening. Sixty 62-d-old pigs (Landrace x Yorkshire (mother) and Pietrain x Duroc (father)) for fattening which were individually weighed and were randomly assigned to 2 dietary treatments with 2 replicate stalls of 15 pigs each. The pigs were fed for 13 weeks ad libitum with a standard wheat-barleysoybean meal compound diet supplemented with 0.3 mg/kg Na2SeO3 and 75 mg/kg vit. E (Control group) and with 0.5 mg/kg Na2SeO3 and 75 mg/kg vit. E (Experimental group). Meat traits in live pigs were measured by ultrasonic equipment Piglog 105. The samples for the analysis of selenium were taken from the M. longissimus dorsi between 12 and last rib and from the liver. Chemical composition of breast meat was being determined by standard methods. The results of conducted trial showed, that the addition of 0.5 mg/g of sodium selenite in the diets of fattening pigs didn't affect productivity parameters, chemical meat composition, accumulation of selenium in the meat tissue, but significant improved the muscularity of pigs. [ABSTRACT FROM AUTHOR]

This study aimed to assess the interaction between vitamin B 6 and selenium (Se) for the flow of Se towards the Se-dependent glutathione peroxidase (GPX) system in response to oxidative stress naturally induced by oestrus in a pubertal pig model. At first oestrus, forty-five gilts were randomly assigned to the experimental diets ( n = 9/group): basal diet (CONT); CONT + 0.3 mg/kg of Na-selenite (MSeB 6 0); MSeB 6 0 + 10 mg/kg of HCl-B 6 (MSeB 6 10); CONT + 0.3 mg/kg of Se-enriched yeast (OSeB 6 0); and OSeB 6 0 + 10 mg/kg of HCl-B 6 (OSeB 6 10). Blood samples were collected at each oestrus (long-term profiles), and daily from day −4 to +3 (slaughter) of the fourth oestrus (peri-oestrus profiles) after which liver, kidneys, and ovaries were collected. For long-term profiles, CONT had lower blood Se than Se-supplemented gilts ( p < 0.01) and OSe was higher than MSe ( p < 0.01). Lower erythrocyte pyridoxal-5-phosphate was found in B 6 0 than B 6 10 ( p < 0.01). No treatment effect was observed on GPX activity. For peri-oestrus profiles, treatment effects were similar to long-term profiles. Treatment effects on liver Se were similar to those for long-term blood Se profiles and OSe had higher renal Se concentrations than MSe gilts ( p < 0.01). Gene expressions of GPX1 , GPX3 , GPX4 , and selenocysteine lyase in liver and kidney were greatest in OSeB 6 10 gilts ( p < 0.05). These results suggest that dietary B 6 modulate the metabolic pathway of OSe towards the GPX system during the peri-oestrus period in pubertal pigs. [ABSTRACT FROM AUTHOR]

Selenium (Se) has emerged as an essential micronutrient but its role in cancer prevention, immunomodulation, thyroid functioning and viral inhibition continues to remain inconclusive. The aim of this review is to dwell upon various factors responsible for mixed results arising out of Se supplementation trials. Some researchers have used inorganic form of Se, sodium selenite, which is less bioavailable and may be toxic if used for prolonged period, while others have opted for organic form, selenomethionine, which may incorporate non-specifically into proteins. In recent times, other organic forms, methylselenocysteine and selenocysteine, being less toxic, more bioavailable and endowed with greater therapeutic value against cancer have attracted the attention of research community. Moreover, appropriate dose (upto 200μg Se per day) may hold the key to bring perceptible beneficial health effects. Further, subjects used in trials should have low plasma Se levels for if they are already having its adequate level then supplementation is likely to be less effective. We conclude that the health effects of Se may largely depend upon its chemical form, dosage and Se-status of population being supplemented. Hence, these factors need to be taken in to account for future studies, trials of disease prevention and treatment by Se supplementation. [ABSTRACT FROM AUTHOR]