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Your search keyword '"Zhou, Zhi-Xiang"' showing total 172 results
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172 results on '"Zhou, Zhi-Xiang"'

4. Scientific Metrological Analysis of Government Services Based on Big Data Analysis and Visualization Software Driven by Information Technology

Author

Zhou, Wei-Keng, Lin, Yan-Tong, Zhou, Zhi-Xiang, Bai, Xin, Yu, Yi-Lin, Pan, Yu-Wen, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Prates, Raquel Oliveira, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Mahmud, Mufti, editor, Kaiser, M. Shamim, editor, Kasabov, Nikola, editor, Iftekharuddin, Khan, editor, and Zhong, Ning, editor

Published
2021
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8. Safety and efficacy of preoperative chemoradiotherapy in fit older patients with intermediate or locally advanced rectal cancer evaluated by comprehensive geriatric assessment: A planned interim analysis of a multicenter, phase II trial

Author

Liu, Wen-Yang, Jin, Jing, Tang, Yuan, Li, Ning, Tang, Yu, Wang, Jun, Cheng, Yun-Jie, Yang, Lin, Fang, Hui, Lu, Ning-Ning, Qi, Shu-Nan, Chen, Bo, Wang, Shu-Lian, Song, Yong-Wen, Liu, Yue-Ping, Li, Ye-Xiong, Liu, Zheng, Zhou, Hai-Tao, Liang, Jian-Wei, Pei, Wei, Wang, Xi-Shan, Zhang, Hai-Zeng, and Zhou, Zhi-Xiang

Published
2021
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9. Bilirubin Elevation During Hospitalization Post Radiofrequency Catheter Ablation of Persistent Atrial Fibrillation: Variation Trend, Related Factors, and Relevance to 1-Year Recurrence

Author

Shao,Jia-Meng, Shen,Bing, Zhou,Zhi-Xiang, D'Angelo,Lucia, James,Shea, Lin,Jia-Feng, Zheng,Cheng, Shao,Jia-Meng, Shen,Bing, Zhou,Zhi-Xiang, D'Angelo,Lucia, James,Shea, Lin,Jia-Feng, and Zheng,Cheng

Abstract

Jia-Meng Shao,&ast; Bing Shen,&ast; Zhi-Xiang Zhou, Lucia D’Angelo, Shea Michaela James, Jia-Feng Lin, Cheng Zheng Department of Cardiology, the Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, 325000, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Cheng Zheng; Jia-Feng Lin, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, East Section of Wenzhou Avenue, No. 1111, Wenzhou, Zhejiang Province, 325000, People’s Republic of China, Tel +86-13587688177 ; +86-13806685498, Email zhengcheng_wzmufey@163.com; linjiafeng_wzmcfey@163.comBackground: The role of total bilirubin (TBIL) in cardiovascular disease has been increasingly recognized in recent decades. Studies have shown a correlation between total bilirubin levels and the prognosis of patients after heart surgery. This study aimed to investigate the clinical significance of bilirubin elevation in persistent atrial fibrillation (PAF) patients who received radiofrequency catheter ablation (RFCA).Methods and Results: A total of 184 patients with PAF who received RFCA were retrospectively studied. Laboratory examinations and demographic data were analyzed to identify independent predictors of TBIL elevation. The relationship between TBIL and prognosis was further investigated. Our results indicated that TBIL increased significantly after RFCA. Multiple linear regression analysis showed that TBIL elevation owned a negative correlation with the percentile of low voltage areas (LVAs) in left atria (β=− 0.490, P< 0.001). In contrast, a positive correlation was observed with the white blood cell (WBC) ratio (β=0.153, P=0.042) and left atrial diameter (LAD) (β=0.232, P=0.025). It was found that postoperative TBIL levels increased and then gradually decreased to baseline within 5 days without intervention. The bilirubin ratio < 1.211 indicated the possibility of

Published
2024

15. Mapping and ablation of ventricular arrhythmias arising from the left ventricular summit.

Author

Zhou, Zhi‐Xiang, Zheng, Cheng, Hu, You‐Dong, and Lin, Jia Feng

Subjects
*HEART anatomy, *CATHETER ablation, *BODY surface mapping, *CORONARY angiography, *VENTRICULAR arrhythmia, *ELECTROCARDIOGRAPHY, *PATIENT safety
Abstract

The left ventricular summit (LVS) refers to the highest portion of the left ventricular outflow tract (LVOT). It is an epicardially delimited triangular area by the left coronary arteries and the coronary venous circulation. Its deep myocardium correlates closely with the left coronary cusp, aortic‐mitral continuity, and right ventricular outflow tract (RVOT), complicating the anatomical relationship. Ventricular arrhythmias (VAs) originating from this area are common, accounting for 14.5% of all VAs origin from left ventricle. Specific electrocardiogram (ECG) characteristics may assist in locating LVS‐VAs pre‐procedure and facilitate procedure planning. However, catheter ablation of LVS‐VAs remains challenging because of anatomical constraints. This paper reviews the recent understanding of LVS anatomy, concludes ECG characteristics, and summarizes current mapping and ablation methods for LVS‐VAs. [ABSTRACT FROM AUTHOR]

Published
2024
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22. Hippo: A New Hub for Atherosclerotic Disease

Author

Liu, Xi-Yan, primary, Zhou, Kun, additional, Tian, Kai-Jiang, additional, Yan, Bin-Jie, additional, Ren, Zhong, additional, Zhou, Zhi-Xiang, additional, Xiong, Wen-Hao, additional, and Jiang, Zhi-Sheng, additional

Published
2022
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29. EndMT: Potential Target of H2S against Atherosclerosis

Author

Liu, Hui-Ting, primary, Zhou, Zhi-Xiang, additional, Ren, Zhong, additional, Yang, Sai, additional, Liu, Lu-Shan, additional, Wang, Zuo, additional, Wei, Dang-Heng, additional, Ma, Xiao-Feng, additional, Ma, Yun, additional, and Jiang, Zhi-Sheng, additional

Published
2021
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33. The Role of Ubiquitin E3 Ligase in Atherosclerosis

Author

Zhou, Zhi-Xiang, primary, Ren, Zhong, additional, Yan, Bin-Jie, additional, Qu, Shun-Lin, additional, Tang, Zhi-Han, additional, Wei, Dang-Heng, additional, Liu, Lu-Shan, additional, Fu, Min-Gui, additional, and Jiang, Zhi-Sheng, additional

Published
2020
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35. Oversleeve anastomosis in laparoscopic sphincter-preserving surgery for low rectal cancer: an overlapped end-to-end anastomosis technique without prophylactic stoma

Author

Su, Hao, primary, Bao, Man-Dula, additional, Luo, Shou, additional, Xu, Zheng, additional, Wang, Peng, additional, Wang, Xue-Wei, additional, Zhao, Chuan-Duo, additional, Liang, Jian-Wei, additional, Liu, Qian, additional, Wang, Xi-Shan, additional, Zhou, Zhi-Xiang, additional, and Zhou, Hai-Tao, additional

Published
2020
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39. Do invasive alien plants differ from non-invasives in dominance and nitrogen uptake in response to variation of abiotic and biotic environments under global anthropogenic change?

Author

Liu, Yuan-Yuan, Sun, Yan, Müller-Schärer, Heinz, Yan, Rong, Zhou, Zhi-Xiang, Wang, Yong-Jian, Yu, Fei-Hai, Liu, Yuan-Yuan, Sun, Yan, Müller-Schärer, Heinz, Yan, Rong, Zhou, Zhi-Xiang, Wang, Yong-Jian, and Yu, Fei-Hai

Abstract

Plant invasion is the outcome of complicated interactions of both biotic and abiotic environments (i.e. eutrophication and human-induced propagules) under global anthropogenic change. Here, we want to know why some alien clonal plant species become invasive and others do not in the introduced range with variations of both abiotic and biotic environments under global anthropogenic change.We selected three invasive alien and three co-occurring, non-invasive alien clonal plant species in China, and grew them under the constant or variable soil nutrient environments in a native community with low or high vegetative propagule pressure (i.e. simulating pressure of anthropogenic alien propagules).Invasive alien species produced more biomass than non-invasives. Interestingly, invasive species benefited significantly greater from high propagule pressure than non-invasives. Biomass and evenness of native communities were greater with non-invasive than with invasive target species. Invasive plants showed a greater increase of leaf N and decrease of leaf C: N ratio when subject to variable nutrients in comparison to constant nutrients than non-invasives.The negative effects of variable nutrients on evenness of native communities were significantly greater under invasive than non-invasive target species. Moreover, biomass of native communities was significantly negatively related to biomass of invasive species. Variable nutrients significantly promoted the negative biomass relationship between non-invasive species and native communities under high propagule pressure and the negative biomass-evenness relationship between invasive species and native communities.Our study suggests that soil nutrient variability and vegetative propagule pressure influence the growth and leaf C and N uptake of alien clonal plant species in native experimental communities, especially under the high propagule pressure and nutrient variability. Invasive alien clonal species have higher performance and a

Published
2019

41. Application of indocyanine green-enhanced near-infrared fluorescence-guided imaging in laparoscopic lateral pelvic lymph node dissection for middle-low rectal cancer

Author

Zhou, Si-Cheng, primary, Tian, Yan-Tao, additional, Wang, Xue-Wei, additional, Zhao, Chuan-Duo, additional, Ma, Shuai, additional, Jiang, Jun, additional, Li, Er-Ni, additional, Zhou, Hai-Tao, additional, Liu, Qian, additional, Liang, Jian-Wei, additional, Zhou, Zhi-Xiang, additional, and Wang, Xi-Shan, additional

Published
2019
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46. EndMT: Potential Target of H2S against Atherosclerosis

Author

Liu, Hui-Ting, Zhou, Zhi-Xiang, Ren, Zhong, Yang, Sai, Liu, Lu-Shan, Wang, Zuo, Wei, Dang-Heng, Ma, Xiao-Feng, Ma, Yun, and Jiang, Zhi-Sheng

Abstract

Atherosclerosis is a chronic arterial wall illness that forms atherosclerotic plaques within the arteries. Plaque formation and endothelial dysfunction are atherosclerosis' characteristics. It is believed that the occurrence and development of atherosclerosis mainly include endothelial cell damage, lipoprotein deposition, inflammation and fibrous cap formation, but its molecular mechanism has not been elucidated. Therefore, protecting the vascular endothelium from damage is one of the key factors against atherosclerosis. The factors and processes involved in vascular endothelial injury are complex. Finding out the key factors and mechanisms of atherosclerosis caused by vascular endothelial injury is an important target for reversing and preventing atherosclerosis. Changes in cell adhesion are the early characteristics of EndMT, and cell adhesion is related to vascular endothelial injury and atherosclerosis. Recent researches have exhibited that endothelial-mesenchymal transition (EndMT) can urge atherosclerosis' progress, and it is expected that inhibition of EndMT will be an object for anti-atherosclerosis. We speculate whether inhibition of EndMT can become an effective target for reversing atherosclerosis by improving cell adhesion changes and vascular endothelial injury. Studies have shown that H2S has a strong cardiovascular protective effect. As H2S has anti- inflammatory, anti-oxidant, inhibiting foam cell formation, regulating ion channels and enhancing cell adhesion and endothelial functions, the current research on H2S in cardiovascular aspects is increasing, but anti-atherosclerosis's molecular mechanism and the function of H2S in EndMT have not been explicit. In order to explore the mechanism of H2S against atherosclerosis, to find an effective target to reverse atherosclerosis, we sum up the progress of EndMT promoting atherosclerosis, and Hydrogen sulfide's potential anti- EndMT effect is discussed in this review.

Published
2021
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47. LMP2-DC Vaccine Elicits Specific EBV-LMP2 Response to Effectively Improve Immunotherapy in Patients with Nasopharyngeal Cancer.

Author

ZENG, Yi, SI, Yong Feng, LAN, Gui Ping, WANG, Zhan, ZHOU, Ling, TANG, Min Zhong, SJ, O'Brien, LAN, Jiao, ZHOU, Xiang Yang, WANG, Yong Li, TANG, Juan, ZHOU, Zhi Xiang, DU, Hai Jun, and LIN, Hui

Subjects
NASOPHARYNX cancer, CYTOTOXIC T cells, INTRADERMAL injections, CANCER patients, IMMUNOTHERAPY, VACCINE effectiveness
Abstract

To evaluate the safety and effectiveness of a vaccine based on latent membrane protein 2 (LMP2) modified dendritic cells (DCs) that boosts specific responses of cytotoxic T lymphocytes (CTLs) to LMP2 before and after intradermal injection in patents with nasopharyngeal carcinoma (NPC). DCs were derived from peripheral blood monocytes of patents with NPC. We prepared LMP2-DCs infected by recombinant adenovirus vector expressing LMP2 (rAd-LMP2). NPC patents were immunized with 2 x 10 LMP2-DCs by intradermal injection at week 0 and after the second and fourth weeks. Specific responses to LMP2 were detected by enzyme-linked immunospot (ELISPOT) assay at week 0 and at the fifth and eighth weeks. Local clinicians performed the follow-up and tracking of patients. We demonstrated that DCs derived from monocytes displayed typical DC morphologies; the expression of LMP2 in the LMP2-DCs vaccine was confirmed by immunocytochemical assay. Twenty-nine patients with NPC were enrolled in this clinical trial. The LMP2-DCs vaccine was well tolerated in all of the patients. Boosted responses to LMP2 peptide sub-pools were observed in 18 of the 29 patients with NPC. The follow-up data of 29 immunized patients from April, 2010 to April 2015 indicated a five-year survival rate of 94.4% in responders and 45.5% in non-responders. In this pilot study, we demonstrated that the LMP2-DCs vaccine is safe and effective in patients with NPC. Specific CTLs responses to LMP2 play a certain role in controlling and preventing the recurrence and metastasis of NPC, which warrants further clinical testing. [ABSTRACT FROM AUTHOR]

Published
2020
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48. A New Method for Ultra-sensitive P24 Antigen Assay Based on Near-infrared Fluorescent Microsphere Immunochromatography.

Author

WANG, Qi, HOU, Mei Ling, LIU, Li Peng, MA, Jing, ZHANG, Xiao Guang, ZHOU, Zhi Xiang, and CAO, Yu Xi

Subjects
ANTIGENS, ENZYME-linked immunosorbent assay, DETECTION limit, IMMUNOASSAY, QUANTITATIVE research
Abstract

To develop a rapid, highly sensitive quantitative method for detecting P24 antigen based on near-infrared fluorescent microsphere immunochromatography. First, we prepared a lateral flow assay test strip, and labeled the detection antibody using a fluorescent microsphere. Second, we optimized the antibody labeling conditions. Third, we optimized the detection conditions. Fourth, we created a working curve. Fifth, we conducted a methodological assessment of the established fluorescent microsphere immunochromatography method. Sixty-six clinical samples were tested, and we compared the established fluorescent microsphere immunochromatography with the quantitative ELISA method. According to the working curve, the detection limit of the method is 3.4 pg/mL, and the detection range is 3.4 pg/mL to 10 ng/mL. The average intra-assay recovery was 99.6%, and the Coefficient of Variation (CV) was 5.4%–8.6%; the average inter-assay recovery was 97.3%, and the CV was 8.5%–11%. The detection rate of fluorescent microsphere immunochromatography was higher than ELISA method, and had a good correlation with ELISA. The P24 antigen quantitative detection method based on near-infrared fluorescent microsphere immunochromatography has the advantages of rapid detection, high sensitivity, and wide detection range; thus, it is suitable for early clinical diagnosis and continuous monitoring of AIDS. [ABSTRACT FROM AUTHOR]

Published
2020
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