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Introduction: Women’s futsal is a sport of intermittent exertion. Female athletes need to comply with nutritional recommendations in order to perform adequately. The aim of this study is to describe the dietary intake and body composition of an elite university indoor football team. Methodology: Observational, descriptive and cross-sectional study carried out on 14 semi-professional players from the University of Alicante. Body composition was calculated using the 4-component model with the equations of the Spanish Society of Sports Medicine. The food consumption habits were assessed using the food consumption frequency questionnaire of the Department of Public Health of the Miguel Hernández University. Statistical analysis was performed with SPSS software. All dependent variables had non-normal distributions and Spearman’s correlation coefficient (Rho) was calculated, the significance level being 0.05 and 0.01.Results: The mean body composition results observed were: 61.69 kg (7.71) kg, height: 1.64 (0.06) m, fat mass percentage 12.00 (3.08) % and muscle mass weight 22.03 (3.82) kg. The somatotypic classification of the sample was endo-mesomorphic. Regarding dietary intake. Dietary intake was generally below the recommendations of the Guide to Healthy Eating for Primary Care and Citizen Groups of the Spanish Society of Community Nutrition (SENC). Correlations were found between the consumption of some foods with anthropometric values such as meat and dairy consumption with higher muscle mass weight (kg).Conclusions: The dietary intake of female players is below the recommendations in most of the food groups. It is necessary to transmit to sportswomen the importance of carrying out adequate nutritional planning specific to their needs in order to maintain acceptable levels of performance as well as an adequate body composition for their sporting level., Introducción: El fútbol sala femenino es un deporte de esfuerzo intermitente. Las deportistas necesitan cumplir con las recomendaciones nutricionales para obtener un rendimiento adecuado. El objetivo del presente estudio es describir la ingesta dietética y la composición corporal de un equipo de élite universitario de fútbol sala. Metodología: Estudio observacional, descriptivo y transversal realizado en 14 jugadoras semi-profesionales de fútbol sala. Se calculó la composición corporal mediante el modelo de 4 com-ponentes con las ecuaciones de la Sociedad Española de Medicina del Deporte. Para evaluar los hábitos de consumo alimentario se empleó el cuestionario de frecuencia de consumo alimentario del departamento de Salud Pública de la Universidad Miguel Hernández. El análisis estadístico se realizó con el software SPSS. Todas las variables dependientes tenían distribuciones no normales y se calculó el coeficiente de correlación de Spearman (Rho), siendo el nivel de significancia esta-blecido de 0,05 y 0,01.Resultados: Los valores medios composición corporal observados fueron: 61,69 (7,71) kg, talla: 1,64 (0,06) m, porcentaje de masa grasa 12,00 (3,08) % y peso masa muscular 22,03 (3,82) kg. La clasificación somatotípica de la muestra fue endo-mesomorfo. Respecto a la ingesta dietética. La ingesta dietética se encontraba generalmente por debajo de las recomendaciones de la Guía de la Alimentación Saludable Para Atención Primaria y Colectivos Ciudadanos de Sociedad Española de Nutrición Comunitaria (SENC). Se encontraron correlaciones entre el consumo de algunos ali-mentos con los valores antropométricos como el consumo de carne y lácteos con un mayor peso de masa muscular (kg).Conclusiones: El consumo alimentario de las jugadoras está por debajo de las recomendaciones en la mayoría de los grupos alimentarios. Es necesario transmitir a las deportistas la importancia de realizar una planificación nutricional adecuada y específica para sus necesidades para poder mante

Objective: Trained immunity (TI) is a de facto memory program of innate immune cells, characterized by immunometabolic and epigenetic changes sustaining enhanced production of cytokines. TI evolved as a protective mechanism against infections; however, inappropriate activation can cause detrimental inflammation and might be implicated in the pathogenesis of chronic inflammatory diseases. In this study, we investigated the role of TI in the pathogenesis of giant cell arteritis (GCA), a large-vessel vasculitis characterized by aberrant macrophage activation and excess cytokine production. Methods: Monocytes from GCA patients and from age- and sex-matched healthy donors were subjected to polyfunctional studies, including cytokine production assays at baseline and following stimulation, intracellular metabolomics, chromatin immunoprecipitation-qPCR, and combined ATAC/RNA sequencing. Immunometabolic activation (i.e. glycolysis) was assessed in inflamed vessels of GCA patients with FDG-PET and immunohistochemistry (IHC), and the role of this pathway in sustaining cytokine production was confirmed with selective pharmacologic inhibition in GCA monocytes. Results: GCA monocytes exhibited hallmark molecular features of TI. Specifically, these included enhanced IL-6 production upon stimulation, typical immunometabolic changes (e.g. increased glycolysis and glutaminolysis) and epigenetic changes promoting enhanced transcription of genes governing pro-inflammatory activation. Immunometabolic changes of TI (i.e. glycolysis) were a feature of myelomonocytic cells in GCA lesions and were required for enhanced cytokine production. Conclusions: Myelomonocytic cells in GCA activate TI programs sustaining enhanced inflammatory activation with excess cytokine production.

Introducción: El fútbol sala femenino es un deporte de esfuerzo intermitente. Las deportistas necesitan cumplir con las recomendaciones nutricionales para obtener un rendimiento adecuado. El objetivo del presente estudio es describir la ingesta dietética y la composición corporal de un equipo de élite universitario de fútbol sala. Metodología: Estudio observacional, descriptivo y transversal realizado en 14 jugadoras semi-profesionales de fútbol sala. Se calculó la composición corporal mediante el modelo de 4 componentes con las ecuaciones de la Sociedad Española de Medicina del Deporte. Para evaluar los hábitos de consumo alimentario se empleó el cuestionario de frecuencia de consumo alimentario del departamento de Salud Pública de la Universidad Miguel Hernández. El análisis estadístico se realizó con el software SPSS. Todas las variables dependientes tenían distribuciones no normales y se calculó el coeficiente de correlación de Spearman (Rho), siendo el nivel de significancia establecido de 0,05 y 0,01. Resultados: Los valores medios composición corporal observados fueron: 61,69 kg (7,71) kg, talla: 1,64 (0,06) m, porcentaje de masa grasa 12,00 (3,08) % y peso masa muscular 22,03 (3,82) Kg. La clasificación somatotípica de la muestra fue endo-mesomorfo. Respecto a la ingesta dietética. La ingesta dietética se encontraba generalmente por debajo de las recomendaciones de la Guía de la Alimentación Saludable Para Atención Primaria y Colectivos Ciudadanos de Sociedad Española de Nutrición Comunitaria (SENC). Se encontraron correlaciones entre el consumo de algunos alimentos con los valores antropométricos como el consumo de carne y lácteos con un mayor peso de masa muscular (kg). Conclusiones: El consumo alimentario de las jugadoras está por debajo de las recomendaciones en la mayoría de los grupos alimentarios. Es necesario transmitir a las deportistas la importancia de realizar una planificación nutricional adecuada y específica para sus necesidades para poder man, Introduction: Women's futsal is a sport of intermittent exertion. Female athletes need to comply with nutritional recommendations in order to perform adequately. The aim of this study is to describe the dietary intake and body composition of an elite university indoor football team. Methodology: Observational, descriptive and cross-sectional study carried out on 14 semi-professional players from the University of Alicante. Body composition was calculated using the 4-component model with the equations of the Spanish Society of Sports Medicine. The food consumption habits were assessed using the food consumption frequency questionnaire of the Department of Public Health of the Miguel Hernández University. Statistical analysis was performed with SPSS software. All dependent variables had non-normal distributions and Spearman's correlation coefficient (Rho) was calculated, the significance level being 0.05 and 0.01. Results: The mean body composition results observed were: 61.69 kg (7.71) kg, height: 1.64 (0.06) m, fat mass percentage 12.00 (3.08) % and muscle mass weight 22.03 kg (3.82), the somatotypic classification of the sample was endo-mesomorphic. Regarding dietary intake. Dietary intake was generally below the recommendations of the Guide to Healthy Eating for Primary Care and Citizen Groups of the Spanish Society of Community Nutrition (SENC). Correlations were found between the consumption of some foods with anthropometric values such as meat and dairy consumption with higher muscle mass weight (kg). Conclusions: The dietary intake of female players is below the recommendations in most of the food groups. It is necessary to transmit to sportswomen the importance of carrying out adequate nutritional planning specific to their needs in order to maintain acceptable levels of performance as well as an adequate body composition for their sporting level.