1. MPBD-LSTM: A Predictive Model for Colorectal Liver Metastases Using Time Series Multi-phase Contrast-Enhanced CT Scans
- Author
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Li, Xueyang, Xiao, Han, Weng, Weixiang, Xu, Xiaowei, and Shi, Yiyu
- Subjects
Electrical Engineering and Systems Science - Image and Video Processing ,Computer Science - Computer Vision and Pattern Recognition - Abstract
Colorectal cancer is a prevalent form of cancer, and many patients develop colorectal cancer liver metastasis (CRLM) as a result. Early detection of CRLM is critical for improving survival rates. Radiologists usually rely on a series of multi-phase contrast-enhanced computed tomography (CECT) scans done during follow-up visits to perform early detection of the potential CRLM. These scans form unique five-dimensional data (time, phase, and axial, sagittal, and coronal planes in 3D CT). Most of the existing deep learning models can readily handle four-dimensional data (e.g., time-series 3D CT images) and it is not clear how well they can be extended to handle the additional dimension of phase. In this paper, we build a dataset of time-series CECT scans to aid in the early diagnosis of CRLM, and build upon state-of-the-art deep learning techniques to evaluate how to best predict CRLM. Our experimental results show that a multi-plane architecture based on 3D bi-directional LSTM, which we call MPBD-LSTM, works best, achieving an area under curve (AUC) of 0.79. On the other hand, analysis of the results shows that there is still great room for further improvement.
- Published
- 2024
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