188 results on '"Wood, David K."'
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2. Stromal architecture directs early dissemination in pancreatic ductal adenocarcinoma
3. iCLOTS: open-source, artificial intelligence-enabled software for analyses of blood cells in microfluidic and microscopy-based assays
4. Genetic reversal of the globin switch concurrently modulates both fetal and sickle hemoglobin and reduces red cell sickling
5. JAK-STAT inhibition reduces endothelial prothrombotic activation and leukocyte–endothelial proadhesive interactions
6. Microfluidic methods to advance mechanistic understanding and translational research in sickle cell disease
7. An irradiated marrow niche reveals a small noncollagenous protein mediator of homing, dermatopontin
8. MetAP2 inhibition modifies hemoglobin S to delay polymerization and improves blood flow in sickle cell disease
9. An Experimental-Computational Approach to Quantify Blood Rheology in Sickle Cell Disease
10. High-throughput assessment of hemoglobin polymer in single red blood cells from sickle cell patients under controlled oxygen tension
11. Next generation microfluidics: fulfilling the promise of lab-on-a-chip technologies
12. CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon RB function in malignant peripheral nerve sheath tumors
13. Distant Relations: Macrophage Functions in the Metastatic Niche
14. SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis
15. Extracellular fluid tonicity impacts sickle red blood cell deformability and adhesion
16. Ex vivo to in vivo model of malignant peripheral nerve sheath tumors for precision oncology
17. Robust microtubule dynamics facilitate low-tension kinetochore detachment in metaphase
18. Deoxygenation Reduces Sickle Cell Blood Flow at Arterial Oxygen Tension
19. High-throughput quantification of red blood cell deformability and oxygen saturation to probe mechanisms of sickle cell disease.
20. CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon restoration of RB function in malignant peripheral nerve sheath tumors
21. Fluorescence Lifetime Measurement of Prefibrillar Sickle Hemoglobin Oligomers as a Platform for Drug Discovery in Sickle Cell Disease
22. Ex vivo to in vivo model of malignant peripheral nerve sheath tumors for precision oncology
23. Microsystems Models of Pathophysiology
24. Extracellular Vesicles Mediate the Intercellular Exchange of Nanoparticles
25. The effect of rigid cells on blood viscosity: linking rheology and sickle cell anemia
26. Feature tracking microfluidic analysis reveals differential roles of viscosity and friction in sickle cell blood
27. Simultaneous quantification of blood rheology and oxygen saturation to evaluate affinity-modifying therapies in sickle cell disease
28. A scalable 3D tissue culture pipeline to enable functional therapeutic screening for pulmonary fibrosis
29. Model-Predicted Clinical Factors Impacting Patient-Specific Response of Sickle Cells to Voxelotor in a Microfluidic Platform
30. Effects of BCL11A Shmir-Induced Post-Transcriptional Silencing on Hemoglobin Polymer Inhibition in Single Red Blood Cells at Physiologic Oxygen Tension
31. Visualizing Sickle Cell Disease Whole Blood Flow and Viscosity through Modifications to Hemoglobin Levels from a Simple Blood Transfusion
32. Multiscale Cues Drive Collective Cell Migration
33. Ionophore-mediated swelling of erythrocytes as a therapeutic mechanism in sickle cell disease
34. An irradiated marrow niche reveals a small non-collagenous protein mediator of homing, dermatopontin
35. Micropatterned comet assay enables high throughput and sensitive DNA damage quantification
36. GPCR‐mediated YAP/TAZ inactivation in fibroblasts via EPAC1/2, RAP2C, and MAP4K7
37. Extracellular vesicles mediate the intercellular exchange of nanoparticles
38. Stromal architecture directs early dissemination in pancreatic ductal adenocarcinoma
39. Robust Pre-Clinical Results and Large-Scale Manufacturing Process for Edit-301: An Autologous Cell Therapy for the Potential Treatment of SCD
40. Ruxolitinib Reduces Endothelial Pro-Adhesive Interactions: Implications for JAK2V617+ MPN Thrombosis
41. Voxelotor Improves Sickle Red Blood Cell Flow Under Hypoxia in a Microfluidic Venule
42. Microscale Collagen and Fibroblast Interactions Enhance Primary Human Hepatocyte Functions in Three-Dimensional Models
43. 5‐(Hydroxymethyl)furfural restores low‐oxygen rheology of sickle trait bloodin vitro
44. A microfluidic platform for simultaneous quantification of oxygen-dependent viscosity and shear thinning in sickle cell blood
45. Microscale Collagen and Fibroblast Interactions Enhance Primary Human Hepatocyte Functions in 3-Dimensional Models
46. Validation of BCL11A As Therapeutic Target in Sickle Cell Disease: Results from the Adult Cohort of a Pilot/Feasibility Gene Therapy Trial Inducing Sustained Expression of Fetal Hemoglobin Using Post-Transcriptional Gene Silencing
47. MetAP2 Inhibition Modifies Hemoglobin S (HbS) to Delay Polymerization and Improve Blood Flow in Sickle Cell Disease
48. SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis
49. Rapid and inefficient kinetics of sickle hemoglobin fiber growth
50. A High-Throughput Workflow to Study Remodeling of Extracellular Matrix-Based Microtissues
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