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18 results on '"Webber, Larry"'

1. The Timing and Sequence of Cardiovascular Health Decline

Author

Pool, Lindsay R., primary, Krefman, Amy E., additional, Labarthe, Darwin R., additional, Greenland, Philip, additional, Juonala, Markus, additional, Kähönen, Mika, additional, Lehtimäki, Terho, additional, Day, Rena Sue, additional, Bazzano, Lydia A., additional, Van Horn, Linda, additional, Liu, Lei, additional, Fernandez-Alonso, Camilo, additional, Webber, Larry S., additional, Pahkala, Katja, additional, Laitinen, Tomi T., additional, Raitakari, Olli T., additional, Lloyd-Jones, Donald M., additional, and Allen, Norrina B., additional

Published
2021
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2. Influential Periods in Longitudinal Clinical Cardiovascular Health Scores

Author

Krefman, Amy E, primary, Labarthe, Darwin, additional, Greenland, Philip, additional, Pool, Lindsay, additional, Aguayo, Liliana, additional, Juonala, Markus, additional, Kähönen, Mika, additional, Lehtimäki, Terho, additional, Day, R Sue, additional, Bazzano, Lydia, additional, Muggeo, Vito M R, additional, Van Horn, Linda, additional, Liu, Lei, additional, Webber, Larry S, additional, Pahkala, Katja, additional, Laitinen, Tomi T, additional, Raitakari, Olli, additional, Lloyd-Jones, Donald M, additional, and Allen, Norrina B, additional

Published
2021
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3. Cardiovascular Health Trajectories From Childhood Through Middle Age and Their Association With Subclinical Atherosclerosis

Author

Allen, Norrina B., primary, Krefman, Amy E., additional, Labarthe, Darwin, additional, Greenland, Philip, additional, Juonala, Markus, additional, Kähönen, Mika, additional, Lehtimäki, Terho, additional, Day, R. Sue, additional, Bazzano, Lydia A., additional, Van Horn, Linda V., additional, Liu, Lei, additional, Alonso, Camilo Fernandez, additional, Webber, Larry S., additional, Pahkala, Katja, additional, Laitinen, Tomi T., additional, Raitakari, Olli T., additional, and Lloyd-Jones, Donald M., additional

Published
2020
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4. Abstract P286: Sex-differences In The Prevalence Of Low Clinical Cardiovascular Health From Childhood To Middle-age

Author

Aguayo, Liliana, primary, Krefman, Amy, additional, Reges, Orna, additional, Davis, Matthew M, additional, Labarthe, Darwin R, additional, Greenland, Philip, additional, Juonala, Markus, additional, Kähönen, Mika, additional, Lehtimäki, Terho, additional, Day, R. Sue, additional, Bazzano, Lydia A, additional, Van Horn, Linda, additional, Alonso, Camilo F, additional, Webber, Larry S., additional, Pahkala, Katja, additional, Laitinen, Tomi T., additional, Raitakari, Olli T, additional, Lloyd-jones, Donald M, additional, and Allen, Norrina B, additional

Published
2020
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5. Abstract 024: The Timing of Cardiovascular Health Decline and Its Association With Subclinical Atherosclerosis in Adulthood

Author

Pool, Lindsay R, primary, Krefman, Amy E, additional, Labarthe, Darwin, additional, Greenland, Philip, additional, Juonala, Markus, additional, Kähönen, Mika, additional, Lehtimäki, Terho, additional, Day, Rena S, additional, Bazzano, Lydia, additional, Van Horn, Linda, additional, Liu, Lei, additional, Alonso, Camilo F, additional, Webber, Larry S, additional, Pahkala, Katja, additional, Laitinen, Tomi T, additional, Raitakari, Olli, additional, Lloyd-Jones, Donald M, additional, and Allen, Norrina B, additional

Published
2019
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6. Abstract 015: Critical Periods in Cardiovascular Health Across the Life Course: A Pooled Cohort Analysis

Author

Allen, Norrina B, primary, Krefman, Amy, additional, Labarthe, Darwin, additional, Greenland, Philip, additional, Juonala, Markus, additional, Kähönen, Mika, additional, Day, S. Rena, additional, Lehtimäki, Terho, additional, Van Horn, Linda, additional, Bazzano, Lydia, additional, Liu, Lei, additional, Alonso, Camilo F, additional, Webber, Larry S, additional, Pahkala, Katja, additional, Laitinen, Tomi, additional, Raitakari, Olli, additional, and Lloyd-Jones, Donald, additional

Published
2018
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8. Species-based comparison of disease severity and risk factors for disseminated Candida infections in pediatric patients

Author

Hawkshead III,John J, Van Dyke,Russell B, Hassig,Susan E, Webber,Larry S, Begue,Rodolfo E, Hawkshead III,John J, Van Dyke,Russell B, Hassig,Susan E, Webber,Larry S, and Begue,Rodolfo E

Abstract

John J Hawkshead III,1 Russell B Van Dyke,2 Susan E Hassig,3 Larry S Webber,4 Rodolfo E Begue5 1Merck & Co, CORE Hospital Specialty Group, Rahway, NJ, 2Department of Pediatrics, Tulane University School of Medicine, 3Department of Epidemiology, 4Department of Biostatistics, Tulane University School of Public Health and Tropical Medicine, 5Department of Pediatrics, Louisiana State University Health Sciences Center, New Orleans, LA, USA Background: Pediatric Candida infections are associated with worse clinical outcomes and increased costs. Yet, it is not definitively known if particular species are associated with more severe illness. Differential risk factor exposures among the species group may also exist. We aimed to determine whether certain Candida species are more strongly associated with worse outcomes, and whether certain risk factors more strongly predispose patients to infection with certain species. Methods: Microbiology lab records from patients seen from 2003 to 2010 at an urban children's hospital were reviewed for invasive or disseminated Candida infections. Data on measures of disease severity/outcome and risk factors were abstracted and analyzed to determine differences associated with various Candida species. Results: Exactly 106 cases of infection were analyzed. Non-albicans species were associated with a significantly longer length of stay postdiagnosis (P=0.03), as well as longer treatment (P=0.02). Candida albicans was associated with a higher number of antihypotensive medications required (P=0.03) and length of mechanical ventilation postdiagnosis (P=0.05). Candida tropicalis was associated with the highest mortality (45.5%). Hypotension, which was found to be significantly associated with concurrent infection, was significantly associated with increased risk of mortality (odds ratio =5.85, P=0.005). Initial choice of antifungal therapy was not associated with differences in eventual patient mortality. Multivariate logistic regr

Published
2016

12. Differences in cardiovascular disease risk when antihypertensive medication adherence is assessed by pharmacy fill versus self-report

Author

Krousel-Wood, Marie, primary, Holt, Elizabeth, additional, Joyce, Cara, additional, Ruiz, Rachael, additional, Dornelles, Adriana, additional, Webber, Larry S., additional, Morisky, Donald E., additional, Frohlich, Edward D., additional, Re, Richard N., additional, He, Jiang, additional, Whelton, Paul K., additional, and Muntner, Paul, additional

Published
2015
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16. Influential Periods in Longitudinal Clinical Cardiovascular Health Scores

Author

Mika Kähönen, Lei Liu, Vito M. R. Muggeo, Amy Krefman, R. Sue Day, Liliana Aguayo, Donald M. Lloyd-Jones, Tomi T. Laitinen, Lydia A. Bazzano, Larry S. Webber, Terho Lehtimäki, Linda Van Horn, Norrina B. Allen, Katja Pahkala, Olli T. Raitakari, Philip Greenland, Markus Juonala, Lindsay R. Pool, Darwin R. Labarthe, Tampere University, Department of Clinical Physiology and Nuclear Medicine, Clinical Medicine, Department of Clinical Chemistry, Krefman, Amy E, Labarthe, Darwin, Greenland, Philip, Pool, Lindsay, Aguayo, Liliana, Juonala, Marku, Kähönen, Mika, Lehtimäki, Terho, Day, R Sue, Bazzano, Lydia, Muggeo, Vito, Van Horn, Linda, Liu, Lei, Webber, Larry S, Pahkala, Katja, Laitinen, Tomi T, Raitakari, Olli, Lloyd-Jones, Donald M, and Allen, Norrina B

Subjects
Adult, Male, Adolescent, Epidemiology, Cardiovascular health, Health Behavior, 3121 Internal medicine, Young Adult, Sex Factors, cohort studies, prevention, Humans, longitudinal studies, risk factors, Medicine, AcademicSubjects/MED00860, Young adult, Child, Aged, business.industry, Age Factors, cardiovascular health, Original Contribution, Middle Aged, Late adolescence, 3126 Surgery, anesthesiology, intensive care, radiology, Middle age, Confidence interval, 3142 Public health care science, environmental and occupational health, Blood pressure, Heart Disease Risk Factors, Female, adolescence, business, Body mass index, cardiovascular epidemiology, Demography, Cohort study
Abstract

The prevalence of ideal cardiovascular health (CVH) among adults in the United States is low and decreases with age. Our objective was to identify specific age windows when the loss of CVH accelerates, to ascertain preventive opportunities for intervention. Data were pooled from 5 longitudinal cohorts (Project Heartbeat!, Cardiovascular Risk in Young Finns Study, The Bogalusa Heart Study, Coronary Artery Risk Development in Young Adults, Special Turku Coronary Risk Factor Intervention Project) from the United States and Finland from 1973 to 2012. Individuals with clinical CVH factors (i.e., body mass index, blood pressure, cholesterol, blood glucose) measured from ages 8 to 55 years were included. These factors were categorized and summed into a clinical CVH score ranging from 0 (worst) to 8 (best). Adjusted, segmented, linear mixed models were used to estimate the change in CVH over time. Among the 18,343 participants, 9,461 (52%) were female and 12,346 (67%) were White. The baseline mean (standard deviation) clinical CVH score was 6.9 (1.2) at an average age of 17.6 (8.1) years. Two inflection points were estimated: at 16.9 years (95% confidence interval: 16.4, 17.4) and at 37.2 years (95% confidence interval: 32.4, 41.9). Late adolescence and early middle age appear to be influential periods during which the loss of CVH accelerates.

Published
2021

17. Primary Care. Patient-Centered Medical Homes In Louisiana Had Minimal Impact On Medicaid Population's Use Of Acute Care And Costs.

Author

Cole, Evan S., Campbell, Claudia, Diana, Mark L., Webber, Larry, and Culbertson, Richard

Subjects
*CRITICAL care medicine, *CERTIFICATION, *MEDICAID, *CHRONIC diseases, *COMPARATIVE studies, *RESEARCH methodology, *MEDICAL care use, *MEDICAL care costs, *PRIMARY health care, *PROBABILITY theory, *REGRESSION analysis, *HEALTH insurance reimbursement, *COST analysis, *PRE-tests & post-tests, *CONTROL groups, *RETROSPECTIVE studies, *PATIENT-centered care, *STATISTICAL models, *DESCRIPTIVE statistics, *SAFETY-net health care providers, *ECONOMICS, *STANDARDS, MEDICAID statistics
Abstract

The patient-centered medical home model of primary care has received considerable attention for its potential to improve outcomes and reduce health care costs. Yet little information exists about the model's ability to achieve these goals for Medicaid patients. We sought to evaluate the effect of patient-centered medical home certification of Louisiana primary care clinics on the quality and cost of care over time for a Medicaid population.We used a quasi-experimental pre-post design with a matched control group to assess the effect of medical home certification on outcomes. We found no impact on acute care use and modest support for reduced costs and primary care use among medical homes serving higher proportions of chronically ill patients. These findings provide preliminary results related to the ability of the patient-centered medical home model to improve outcomes for Medicaid beneficiaries. The findings support a case-mix-adjusted payment policy for medical homes going forward. [ABSTRACT FROM AUTHOR]

Published
2015
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18. Bariatric aftercare and outcomes in the Medicaid population following sleeve gastrectomy.

Author

Bellows CF, Gauthier JM, and Webber LS

Subjects
Adult, Aftercare economics, Body Mass Index, Female, Follow-Up Studies, Humans, Male, Obesity, Morbid economics, Retrospective Studies, Treatment Outcome, United States, Aftercare methods, Gastrectomy methods, Laparoscopy methods, Medicaid, Obesity, Morbid surgery, Weight Loss
Abstract

Background: Medicaid patients tend to have poor access to care and suffer from more obesity and obesity-related co-morbidities compared to their privately insured counterparts. The impact of Medicaid status on outcomes after laparoscopic sleeve gastrectomy (LSG) is unknown. The aim of this study was to identify factors that influence outcomes following LSG in the adult Medicaid population of Louisiana with particular focus on adherence to bariatric aftercare attendance and access to care., Methods: A retrospective review of 63 Medicaid patients undergoing LSG was performed. Demographic data, access to care, weight, co-morbidities morbidity, and mortality were analyzed. Changes in weight and obesity-related co-morbidities were analyzed for patients with ≥12 months of follow-up. Regression analyses were used for estimating the relationships among variables., Results: The majority of patients were female and non-Caucasian. The mean age was 38.6 years. Morbidity was 16% and mortality was 0%. The average distance traveled to clinic was 71.9 miles. Within the first year only 10% of the patients attended all post-operative clinic visits. A multiple logistic model showed that the only predictor of clinic attendance was increased age. At a mean follow-up of 17.7 months, the mean percent excess body weight loss was 47.2%. Greater pre-surgical weight was the only variable associated with suboptimal weight loss. Improvement or resolution of all major co-morbidities was seen in 65% of patients., Conclusion: Medicaid patients had a poor attendance at bariatric surgery follow up appointments. Since long-term follow-up is critical, we needed to develop strategies that will optimize follow-up in this patient population.

Published
2014
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