7 results on '"Vandelli C"'
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2. AISF position paper on liver transplantation and pregnancy: Women in Hepatology Group, Italian Association for the Study of the Liver (AISF)
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Burra, P, Rodríguez-Castro, K, Guarino, M, Morisco, F, Villa, E, Mazzella, G, Women in Hepatology Group, Italian Association for the Study of the Liver (AISF) (Alisi, A, Balsano, C, Bernabucci, V, Berzigotti, A, Brunetto, M, Bugianesi, E, Calvaruso, V, Cariani, E, Coco, B, Colle, I, Critelli, R, De Martin, E, Del Buono, M, Fabregat, I, Faillaci, F, Fattovich, G, Floreani, A, Garcia-Tsao, G, Housset, C, Karampatou, A, Lei, B, Mangia, A, Martinez-Chantar, Ml, Milosa, F, Nasta, P, Ozben, T, Pollicino, T, Ponti, Ml, Pontisso, P, Reeves, H, Rendina, M, Rodríguez-Castro, Ki, Sagnelli, C, Sebastiani, Giulia, Smedile, A, Taliani, G, Vandelli, C, Vanni, E, Vukotic, R, Zignego, Al), Alisi A, Balsano C, Bernabucci V, Berzigotti A, Brunetto M, Bugianesi E, Burra P, Calvaruso V, Cariani E, Coco B, Colle I, Critelli R, De Martin E, Del Buono M, Fabregat I, Faillaci F, Fattovich G, Floreani A, Garcia-Tsao G, Housset C, Karampatou A, Lei B, Mangia A, Martinez-Chantar ML, Milosa F, Morisco F, Nasta P, Ozben T, Pollicino T, Ponti ML, Pontisso P, Reeves H, Rendina M, Rodríguez-Castro KI, Sagnelli C, Sebastiani G, Smedile A, Taliani G, Vandelli C, Vanni E, Villa E, Vukotic R, Zignego AL, Burra P, Rodríguez-Castro K, Guarino M, Morisco F, Villa E, Mazzella G., Alisi, A, Balsano, C, Bernabucci, V, Berzigotti, A, Brunetto, M, Bugianesi, E, Burra, P, Calvaruso, V, Cariani, E, Coco, B, Colle, I, Critelli, R, De Martin, E, Del Buono, M, Fabregat, I, Faillaci, F, Fattovich, G, Floreani, A, Garcia-Tsao, G, Housset, C, Karampatou, A, Lei, B, Mangia, A, Martinez-Chantar, Ml, Milosa, F, Morisco, F, Nasta, P, Ozben, T, Pollicino, T, Ponti, Ml, Pontisso, P, Reeves, H, Rendina, M, Rodríguez-Castro, Ki, Sagnelli, C, Sebastiani, G, Smedile, A, Taliani, G, Vandelli, C, Vanni, E, Vukotic, R, Zignego, Al, Rodríguez-Castro, K, Guarino, M, Villa, E, Mazzella, G., Garcia Tsao, G, Martinez Chantar, Ml, Morisco, Filomena, Rodríguez Castro, Ki, Rodríguez Castro, K, Guarino, Maria, Alisi, Anna, Balsano, Clara, Bernabucci, Veronica, Berzigotti, Annalisa, Brunetto, Maurizia, Bugianesi, Elisabetta, Burra, Patrizia, Calvaruso, Vincenza, Cariani, Elisabetta, Coco, Barbara, Colle, Isabelle, Critelli, Rosina, De Martin, Eleonora, Del Buono, Mariagrazia, Fabregat, Isabel, Faillaci, Francesca, Fattovich, Giovanna, Floreani, Annarosa, Garcia-tsao, Guadalupe, Housset, Chantal, Karampatou, Aimilia, Lei, Barbara, Mangia, Alessandra, Martinez-chantar, Maria Luz, Milosa, Fabiola, Nasta, Paola, Ozben, Tomri, Pollicino, Teresa, Ponti, Maria Laura, Pontisso, Patrizia, Reeves, Helen, Rendina, Maria, Rodrãguez-castro, Kryssia Isabel, Sagnelli, Caterina, Sebastiani, Giada, Smedile, Antonella, Taliani, Gloria, Vandelli, Carmen, Vanni, Ester, Villa, Erica, Vukotic, Ranka, Zignego, Anna Linda, Rodrãguez-castro, Kryssia, and Mazzella, Giuseppe
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Risk Assessment ,Fertility ,Immunosuppression ,Liver transplantation ,Pregnancy ,Immunosuppressive Agent ,Medical ,Hepatology ,Gastroenterology ,Humans ,Obstetric Labor Complication ,Societies, Medical ,Postpartum Period ,Pregnancy Outcome ,Contraception ,Female ,Italy ,Obstetric Labor Complications ,Practice Guidelines as Topic ,Pregnancy Complications ,Immunosuppressive Agents ,Liver Transplantation ,Pregnancy Complication ,surgical procedures, operative ,Societies ,Human - Abstract
After the first successful pregnancy in a liver transplant recipient in 1978, much evidence has accumulated on the course, outcomes and management strategies of pregnancy following liver transplantation. Generally, liver transplantation restores sexual function and fertility as early as a few months after transplant. Considering that one third of all liver transplant recipients are women, that approximately one-third of them are of reproductive age (18-49 years), and that 15% of female liver transplant recipients are paediatric patients who have a >70% probability of reaching reproductive age, the issue of pregnancy after liver transplantation is rather relevant, and obstetricians, paediatricians, and transplant hepatologists ever more frequently encounter such patients. Pregnancy outcomes for both the mother and infant in liver transplant recipients are generally good, but there is an increased incidence of preterm delivery, hypertension/preeclampsia, foetal growth restriction, and gestational diabetes, which, by definition, render pregnancy in liver transplant recipients a high-risk one. In contrast, the risk of congenital anomalies and the live birth rate are comparable to those of the general population. Currently there are still no robust guidelines on the management of pregnancies after liver transplantation. The aim of this position paper is to review the available evidence on pregnancy in liver transplant recipients and to provide national Italian recommendations for clinicians caring for these patients. (C) 2016 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
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- 2016
3. Heating, ventilation and air conditioning (HVAC) system, microbial air contamination and surgical site infection in hip and knee arthroplasties: the GISIO-SItI Ischia study
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Pasquarella, C., Barchitta, M., D'Alessandro, D., Cristina, M. L., Mura, I., Nobile, M., Auxilia, F., Agodi, A., Avondo, S., Basile, G., Bellocchi, P., Canino, R., Capozzi, C., Casarin, R., Cavasin, M., Contegiacomo, P., Costa, S., Deriu, M. G., Evola, F. R., Farsetti, P., Grandi, A., Guareschi, D., Longhitano, A. M., Longo, G., Malatesta, R., Marenghi, P., Marras, F., Maso, A., Mattaliano, A. R., Mazzarol, G., Montella, M. T., Moscato, U., Navone, P., Romeo, M. A., Rossi, F., Ruffino, M., Saccani, E., Santangelo, C., Sartini, M., Sessa, G., Tardivo, S., Tranquilli Leali, P., Torregrossa, M. V., Vandelli, C., and Vitali, P.
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Operating Rooms ,Settore MED/42 - Igiene Generale e Applicata ,Arthroplasty, Replacement, Hip ,Air Microbiology ,infectious diseases ,HVAC ,Arthroplasty ,Heating ,Air microbial contamination, Arthroplasty, Heating, HVAC, Operating theatre, Surgical site infections, Ventilation and air conditioning system, Public Health, Environmental and Occupational Health, Infectious Diseases ,Settore MED/33 - Malattie Apparato Locomotore ,Humans ,Surgical Wound Infection ,Operating theatre ,Ventilation and air conditioning system ,Air Conditioning ,Arthroplasty, Replacement, Knee ,environmental and occupational health ,Air microbial contamination ,Surgical site infections ,public health ,Ventilation ,Italy ,Elective Surgical Procedures ,Population Surveillance ,air microbial contamination ,arthroplasty ,heating ,operating theatre ,surgical site infections ,ventilation and air conditioning system ,public health, environmental and occupational health - Abstract
Recent studies have questioned the role of unidirectional airflow ventilation system in reducing surgical site infection (SSI) in prosthetic implant surgery. The aim of the ISChIA study ("Infezioni del Sito Chirurgico in Interventi di Artroprotesi" which means "Surgical site infections in arthroplasty surgery") was to evaluate, as a contribution to this debate, the association between heating, ventilation and air conditioning systems, microbial air contamination and surgical site infection in hip and knee arthroplasty.The study was performed from March 2010 to February 2012 in 14 hospitals, for a total of 28 operating theatres: 16 were equipped with vertical unidirectional airflow ventilation (U-OTs), 6 with mixed airflow ventilation (M-OTs), 6 with turbulent airflow ventilation (T-OTs). Microbial air contamination in the operating theatre was evaluated by means of passive (Index of Microbial Air contamination, IMA) and active (Colony Forming Units per cubic metre, cfu/m3) sampling. SSI surveillance was carried out according to the Hospitals in Europe Link for Infection Control through Surveillance protocol.A total of 1,285 elective prosthesis procedures (61.1% hip and 38.9% knee) were included in the study. The results showed a wide variability of the air microbial contamination in operating theatres equipped with unidirectional airflow. The recommended values of ≤2 IMA and ≤10 cfu/m3 were exceeded, respectively, by 58.9% and 46.4% of samples from U-OTs and by 87.6% and 100% of samples from M-OTs. No significant difference was observed between SSI cumulative incidence in surgical procedures performed in U-OTs compared with those performed in T-OTs. A lower risk of SSI, even though not statistically significant, was shown in surgical procedures performed in U-OTs with a microbial air contamination within the recommended values (≤2 IMA and ≤10 cfu/m3) compared with those performed in U-OTs where these limits were exceeded, and compared with those performed in T-OTs with microbial air contamination within the recommended values for this type of OTs (≤25 IMA, ≤180 cfu/m3.ISChIA study did not show a protective effect of unidirectional airflow compared with turbulent airflow in arthroplasty surgery. However, the frequent exceeding of recommended air microbial contamination values in OTs equipped with unidirectional airflow, and the lower SSI risk in surgical procedures performed in compliant U-OTs compared with those performed in non-compliant U-OTs and with those performed in compliant T-OTs, suggest the need of further studies, which should consider air microbial contamination and other aspects of SSI prevention that may negate the potential benefits of the ventilation system; differences in intrinsic and extrinsic risk factors, medical treatment and surgical technique are also to be considered. Training interventions aimed at improving the behaviour of operators are essential.
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- 2018
4. Proteasome dysfunction as a reversible defect underlying virus-specific CD8 cell exhaustion in chronic hepatitis B
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Fisicaro, P., primary, Barili, V., additional, Acerbi, G., additional, Montanini, B., additional, Laccabue, D., additional, Guerrieri, F., additional, Massari, M., additional, Vandelli, C., additional, Salerno, D., additional, Grossi, G., additional, Alfieri, A., additional, Lampertico, P., additional, Giuberti, T., additional, Missale, G., additional, Levrero, M., additional, Ottonello, S., additional, and Ferrari, C., additional
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- 2017
- Full Text
- View/download PDF
5. Missed treatment in an Italian HBV infected patients cohort: HBV RER
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Cuomo, Gianluca, primary, Borghi, Vanni, additional, Andreone, Pietro, additional, Massari, Marco, additional, Villa, Erica, additional, Pietrangelo, Antonello, additional, Verucchi, Gabriella, additional, Ferrari, Carlo, additional, Ferrari, C., additional, Giuberti, T., additional, Villa, E., additional, Andreone, P., additional, Pietrangelo, A., additional, Abbati, G., additional, Magnani, G., additional, Massari, M., additional, Verucchi, G., additional, Cancellieri, C., additional, Ricca Rosellini, S., additional, Levantesi, F., additional, Mazzella, G., additional, Sacchini, D., additional, Fornaciari, G., additional, Mussini, C., additional, Borghi, V., additional, Foschi, F., additional, Libanore, M., additional, Carradori, S.D., additional, Contini, C., additional, Ballardini, G., additional, Macchia, S., additional, Boccia, S., additional, Vandelli, C., additional, Bassi, P., additional, Zanotti, M., additional, Loria, P., additional, Sbolli, G., additional, Fornari, F., additional, di Maira, P.V., additional, Bellentani, S., additional, Arlotti, M., additional, Grosso, C., additional, Bolondi, G., additional, Pazzi, P., additional, Mazzocchi, A., additional, Govoni, A., additional, Fusaroli, P., additional, Giacomoni, P.L., additional, Lenzi, M., additional, and Pedretti, G., additional
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- 2016
- Full Text
- View/download PDF
6. Compliance with guidelines on antibiotic prophylaxis in hip and knee arthroplasty in Italy: results of the GISIO-ISChIA project
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Agodi, A, Auxilia, F, Barchitta, M, Cristina, M, Mura, I, Nobile, M, Pasquarella, C, Avondo, S, Bellocchi, P, Canino, R, Capozzi, C, Casarin, R, Contegiacomo, P, Evola, R, Farsetti, P, Grandi, A, Guareschi, D, Longhitano, A, Longo, G, Malatesta, R, Marenghi, P, Marras, F, Mattaliano, A, Mazzarol, G, Montella, M, Moscato, U, Navone, P, Rossi, F, Sartini, M, Sessa, G, Tardivo, S, Tranquilli Leali, P, Torregrossa, M, Vandelli, C, and Vitali, P
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Orthopedic surgery ,Hip ,Time Factors ,Settore MED/18 - CHIRURGIA GENERALE ,Settore MED/42 - Igiene Generale e Applicata ,Arthroplasty, Replacement, Hip ,Replacement ,Antibiotic Prophylaxis ,Arthroplasty ,Anti-Bacterial Agents ,Duration ,Perioperative antibiotic prophylaxis ,Timing ,Arthroplasty, Replacement, Knee ,Guideline Adherence ,Humans ,Italy ,Practice Guidelines as Topic ,Surgical Wound Infection ,Duration, Orthopedic surgery, Perioperative antibiotic prophylaxis, Timing ,Knee - Abstract
The Perioperative Antibiotic Prophylaxis (PAP) contributes considerably to the total amount of antibiotics used in hospitals and has been shown to be associated with increase in antibiotic resistance and healthcare costs. The level of compliance with the national guidelines of current practices of PAP for elective hip and knee prosthesis procedures in a network of Italian hospitals (the multicentre Surgical Site Infection surveillance project GISIO-ISChIA), has been evaluated.Compliance of the current prophylactic antibiotic practices with the published national guidelines was assessed for each included operative procedure, considering indication, timing of administration, prescribed antimicrobial agent and total duration of prophylaxis.A total of 14 hospitals and 1285 surgical procedures were included. 99.4% of patients received antimicrobial prophylaxis pre-operatively and 73.0% of patients received PAP within the recommended time period (within 60 minutes before incision). The rate of compliance with discontinuation of PAP within 24 hours after initiation of surgery was 70.2%. Taking into account all doses administered, the antibiotic was chosen appropriately in 57.7% of patients. PAP was performed appropriately, in accordance with national guidelines, in 43.6% of surgical operations.Given the increasing number of replacement procedures in Italy and in Europe, the gap between the evidence-based guidelines and practice must be appropriately addressed in order to improve PAP practices.
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- 2015
7. [Cost analysis of sterilization facilities in the Rizzoli Hospital (Bologna, Italy): a study of different organizational models].
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Montella MT, Onofri C, Onofri D, Bullini D, Vandelli C, Effat S, and Pasquarella C
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- Italy, Costs and Cost Analysis, Hospitals, Models, Organizational, Sterilization economics, Sterilization organization & administration
- Abstract
Preventing healthcare-associated infections requires a number of actions, including adequate disinfection and sterilization of medical devices. A cost analysis of hospital sterilization processes is fundamental to increase quality and safety, reduce costs and to make a decision about outsourcing. The aim of this analysis was to determine the cost of sterilization and the average cost of surgical procedures at the Rizzoli hospital in Bologna (Italy), a largesurgical hospital that performs more than 11,000 surgical procedures per year.
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- 2015
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