10 results on '"Tamiru Oljira"'
Search Results
2. Identification of colorblindness among selected primary school children in Hararghe Region, Eastern Ethiopia
- Author
-
Temesgen Tola Geletu, Manikandan Muthuswamy, and Tamiru Oljira Raga
- Subjects
Medicine - Abstract
Background: Color vision deficiency or colorblindness, is the inability or reduced ability to distinguish different color spectra, particularly, red & green under normal lighting conditions with unaided eye. Red-green colorblindness is heritable genetic disorder and most prevalent type of color vision deficiency and its incidence varies between different ethnicity and sex and shows disparity in different parts/regions of the world. Objectives: This study was conducted to find out the prevalence of colorblindness in Eastern part of Ethiopia and identify its distribution among Harari, Oromo and Ethio-Somali ethnic groups. Methods: A total of 2103 (1043 male & 1060 female) students belonging to the three ethnic groups were randomly selected from nine selected primary schools and were screened for color vision deficiency by using Ishihara’s tests for color vision deficiency and the data analysis was carried out with SPSS version 16.0. Results: Among those screened for color vision deficiency, 33 of them (1.6%) were diagnosed with colorblindness out of which 31 were male and 2 were female. Out of this; 15, 7 and 11 were from Harari, Oromo and Somali ethnicity respectively. The highest incidence was observed among Harari males (4.2%) and no color vision deficiency was recorded among Oromo females. Deuteronomally was the most frequent color vision defect detected (16, 48.5%) and protanopia was the least detected color vision deficiency with 4 cases (12.1%). Conclusion: Results from this study show similar prevalence rate with previously reported study in Ethiopia for Harari ethnic group but lower prevalence rates for Somali and Oromo ethnic groups. Early detection of colorblindness is important for children to select their future profession and take necessary precautions in their everyday activities. Families and other concerned bodies should also take the case of children with colorblindness into consideration while dealing with them. Keywords: Color vision deficiency, Red-green, Ishihara test, Eastern Ethiopia
- Published
- 2018
- Full Text
- View/download PDF
3. Extraction of Papain from Papaya (Carica papaya L.) Fruit Latex and Its Application in Transforming Tannery Raw Trimming
- Author
-
Olyad Erba Urgessa, Duguma Dibbisa Itana, and Tamiru Oljira Raga
- Subjects
Gelatin ,Optimization ,Papain ,Papaya latex ,Tannery waste ,Science - Abstract
The leather industry is one of the major polluting industries in Ethiopia. Environment protection has prompted industrialists and scientists to re-look at transformation of tannery solid waste materials to valuable products using enzymatic hydrolysis. Acid and liming process of gelatin production generate large amount of wastes and used limited raw materials. This study was therefore, aimed to extract papain from papaya fruit latex and use it for transforming raw trimming to gelatin. Extraction and purification was carried out using Three Phase Partitioning. Protein content and protease activity were determined using lowry and casein hydrolysis method, respectively. Effect of agitation time taken, crude extract to t-butanol ratio, ammonium sulphate concentration and temperature on purification fold and activity recovery of papain was evaluated and process was optimized. At its optimized parameters, the intermediate phase of TPP showed 94.14% percentage of protease activity recovery and 8.31 purification fold. At its optimized parameters, bottom phase showed 75.15% percentage of protease activity recovery and 6.61 purification fold. Enzymatic hydrolysis of raw trimming produced 68 wt% and 64 wt% gelatin recovery from the use of crude and intermediate phase papain, respectively. Relatively low gel strength of gelatin with bloom value of 95g and 87g were obtained from hydrolysis of raw trimming by intermediate and crude papain, respectively. This study showed that the use of crude extract for transforming raw trimming to gelatin was found good as it showed comparable protease activity. The TPP can be employed for the extraction and purification of proteases from papaya fruit for industrial application that requires it in partial pure form.
- Published
- 2019
- Full Text
- View/download PDF
4. Identification of colorblindness among selected primary school children in Hararghe Region, Eastern Ethiopia
- Author
-
Geletu, Temesgen Tola, Muthuswamy, Manikandan, and Raga, Tamiru Oljira
- Published
- 2018
- Full Text
- View/download PDF
5. Correlation and Path Coefficient Analyses in Hot Pepper (Capsicum annum L.)
- Author
-
Bantayehu Bekele, Yohanes Petros, Tamiru Oljira, and Mebeaselassie Andargie
- Subjects
food and beverages - Abstract
To assess the correlation and find out the direct and indirect effect of yield attributing traits on yield, twenty six accessions and four varieties during the off-season period from November 2016 to May 2017 under irrigation. at Dire dawa, Ethiopia. The experiment was conducted using RCBD design with three replications. Plant height, primary branch per plot, days to fifty percent flowering, stem width, number of fruit per plant, fruit length, days to maturity and number of fruit per plant were positive and highly significantly correlated with dry fruit yield per plot at both genotypic and phenotypic correlation. Plant height (0.1081), number of fruit per plant (0.2610), fruit length (0.4293), stem width (0.4059), pedicel length (0.0122), days to maturity (0.0401) and internode length (0.0227) exerted positive direct effect on dry fruit yield per plot at phenotypic level. Genotypic path analysis showed that days to fifty percent flowering (0.0956), stem width (0.5867), fruit length (0.3671), plant height (0.0754), number of fruit per plant (0.2673) and internode length (0.0079)had positive direct effect. The direct effect of these characters on dry fruit yield per plot indicates that improvement on these traits may increase yield.
- Published
- 2022
- Full Text
- View/download PDF
6. Evidence of the interplay of genetics and culture in Ethiopia
- Author
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Neil Bradman, Nancy Bird, Saioa López, Sam Morris, Gavin Band, Lucy van Dorp, Tamiru Oljira, Endashaw Bekele, Mark G. Thomas, Ayele Tarekegn, Roger Blench, Garrett Hellenthal, Ephrem Mekonnen, López, Saioa [0000-0003-2936-4070], Band, Gavin [0000-0002-1710-9024], van Dorp, Lucy [0000-0002-6211-2310], Bird, Nancy [0000-0003-2596-874X], Oljira, Tamiru [0000-0002-8186-1667], Mekonnen, Ephrem [0000-0003-0416-649X], Thomas, Mark G. [0000-0002-2452-981X], Hellenthal, Garrett [0000-0002-5760-8020], Apollo - University of Cambridge Repository, and Thomas, Mark G [0000-0002-2452-981X]
- Subjects
0301 basic medicine ,Male ,Population genetics ,Science ,Ethnic group ,General Physics and Astronomy ,Black People ,Ethnic Groups ,Big Five personality traits and culture ,631/208/457 ,General Biochemistry, Genetics and Molecular Biology ,03 medical and health sciences ,0302 clinical medicine ,Genetic similarity ,Geographical distance ,Cultural diversity ,Genetic variation ,Ethnicity ,Humans ,10. No inequality ,Social Factors ,Language ,African Continental Ancestry Group ,2. Zero hunger ,Multidisciplinary ,45 ,article ,Genetic Variation ,Linguistics ,General Chemistry ,Cultural Diversity ,631/208/728 ,Genetic differentiation ,Religion ,030104 developmental biology ,Geography ,Genetics, Population ,Haplotypes ,Evolutionary biology ,631/208/457/649 ,Multigene Family ,Genetic structure ,Female ,Ethiopia ,030217 neurology & neurosurgery - Abstract
The rich linguistic, ethnic and cultural diversity of Ethiopia provides an unprecedented opportunity to understand the level to which cultural factors correlate with–and shape–genetic structure in human populations. Using primarily new genetic variation data covering 1,214 Ethiopians representing 68 different ethnic groups, together with information on individuals’ birthplaces, linguistic/religious practices and 31 cultural practices, we disentangle the effects of geographic distance, elevation, and social factors on the genetic structure of Ethiopians today. We provide evidence of associations between social behaviours and genetic differences among present-day peoples. We show that genetic similarity is broadly associated with linguistic affiliation, but also identify pronounced genetic similarity among groups from disparate language classifications that may in part be attributable to recent intermixing. We also illustrate how groups reporting the same culture traits are more genetically similar on average and show evidence of recent intermixing, suggesting that shared cultural traits may promote admixture. In addition to providing insights into the genetic structure and history of Ethiopia, we identify the most important cultural and geographic predictors of genetic differentiation and provide a resource for designing sampling protocols for future genetic studies involving Ethiopians., Ethiopia is one of the most ethnically and culturally diverse countries. Here, the authors look at genetic and cultural variation in 1,214 Ethiopians to unravel the relationship between genetic admixture and cultural factors.
- Published
- 2021
7. Identification of colorblindness among selected primary school children in Hararghe Region, Eastern Ethiopia
- Author
-
Tamiru Oljira Raga, Temesgen Tola Geletu, and Manikandan Muthuswamy
- Subjects
Color vision deficiency, Red-green, Ishihara test, Eastern Ethiopia ,genetic structures ,business.industry ,Color vision ,Everyday activities ,Incidence (epidemiology) ,lcsh:R ,05 social sciences ,Ethnic group ,Prevalence ,lcsh:Medicine ,Early detection ,General Medicine ,Somali ,050105 experimental psychology ,language.human_language ,03 medical and health sciences ,0302 clinical medicine ,030221 ophthalmology & optometry ,language ,Lower prevalence ,Medicine ,0501 psychology and cognitive sciences ,business ,Demography - Abstract
Background: Color vision deficiency or colorblindness, is the inability or reduced ability to distinguish different color spectra, particularly, red & green under normal lighting conditions with unaided eye. Redgreen colorblindness is heritable genetic disorder and most prevalent type of color vision deficiency and its incidence varies between different ethnicity and sex and shows disparity in different parts/regions of the world.Objectives: This study was conducted to find out the prevalence of colorblindness in Eastern part of Ethiopia and identify its distribution among Harari, Oromo and Ethio-Somali ethnic groups.Methods: A total of 2103 (1043 male & 1060 female) students belonging to the three ethnic groups were randomly selected from nine selected primary schools and were screened for color vision deficiency by using Ishihara’s tests for color vision deficiency and the data analysis was carried out with SPSS version 16.0.Results: Among those screened for color vision deficiency, 33 of them (1.6%) were diagnosed with colorblindness out of which 31 were male and 2 were female. Out of this; 15, 7 and 11 were from Harari, Oromo and Somali ethnicity respectively. The highest incidence was observed among Harari males (4.2%) and no color vision deficiency was recorded among Oromo females. Deuteronomally was the most frequent color vision defect detected (16, 48.5%) and protanopia was the least detected color vision deficiency with 4 cases (12.1%).Conclusion: Results from this study show similar prevalence rate with previously reported study in Ethiopia for Harari ethnic group but lower prevalence rates for Somali and Oromo ethnic groups. Early detection of colorblindness is important for children to select their future profession and take necessary precautions in their everyday activities. Families and other concerned bodies should also take the case of children with colorblindness into consideration while dealing with them.Keywords: Color vision deficiency, Red-green, Ishihara test, Eastern Ethiopia
- Published
- 2018
- Full Text
- View/download PDF
8. Extraction of Papain from Papaya (Carica papaya L.) Fruit Latex and Its Application in Transforming Tannery Raw Trimming
- Author
-
Urgessa, Olyad Erba, Itana, Duguma Dibbisa, and Raga, Tamiru Oljira
- Subjects
Gelatin ,Optimization ,Papain ,Papaya latex ,Tannery waste ,lcsh:Q ,lcsh:Science - Abstract
The leather industry is one of the major polluting industries in Ethiopia. Environment protection has prompted industrialists and scientists to re-look at transformation of tannery solid waste materials to valuable products using enzymatic hydrolysis. Acid and liming process of gelatin production generate large amount of wastes and used limited raw materials. This study was therefore, aimed to extract papain from papaya fruit latex and use it for transforming raw trimming to gelatin. Extraction and purification was carried out using Three Phase Partitioning. Protein content and protease activity were determined using lowry and casein hydrolysis method, respectively. Effect of agitation time taken, crude extract to t-butanol ratio, ammonium sulphate concentration and temperature on purification fold and activity recovery of papain was evaluated and process was optimized. At its optimized parameters, the intermediate phase of TPP showed 94.14% percentage of protease activity recovery and 8.31 purification fold. At its optimized parameters, bottom phase showed 75.15% percentage of protease activity recovery and 6.61 purification fold. Enzymatic hydrolysis of raw trimming produced 68 wt% and 64 wt% gelatin recovery from the use of crude and intermediate phase papain, respectively. Relatively low gel strength of gelatin with bloom value of 95g and 87g were obtained from hydrolysis of raw trimming by intermediate and crude papain, respectively. This study showed that the use of crude extract for transforming raw trimming to gelatin was found good as it showed comparable protease activity. The TPP can be employed for the extraction and purification of proteases from papaya fruit for industrial application that requires it in partial pure form., Ethiopian Journal of Sciences and Sustainable Development, Vol 6 No 2 (2019): EJSSD
- Published
- 2019
9. Tracing the route of modern humans out of Africa by using 225 human genome sequences from Ethiopians and Egyptians
- Author
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Yuan Chen, Toomas Kivisild, Stephan Schiffels, Ephrem Mekonnen, Petr Danecek, Luca Pagani, Tamiru Oljira, Deepti Gurdasani, Donata Luiselli, Chris Tyler-Smith, Neil Bradman, Marc Haber, Richard Durbin, Rosemary Ekong, Pierre Zalloua, Aylwyn Scally, Endashaw Bekele, Yali Xue, Pagani, Luca, Schiffels, Stephan, Gurdasani, Deepti, Danecek, Petr, Scally, Aylwyn, Chen, Yuan, Xue, Yali, Haber, Marc, Ekong, Rosemary, Oljira, Tamiru, Mekonnen, Ephrem, Luiselli, Donata, Bradman, Neil, Bekele, Endashaw, Zalloua, Pierre, Durbin, Richard, Kivisild, Tooma, and Tyler-Smith, Chris
- Subjects
Human Migration ,Population ,Egypt, Ancient ,Molecular Sequence Data ,Black People ,Biology ,Coalescent theory ,03 medical and health sciences ,Genetic ,Principal Component Analysi ,Out of africa ,Report ,Genetics ,Haplotype ,Humans ,Genetics(clinical) ,education ,Genetics (clinical) ,History, Ancient ,030304 developmental biology ,African Continental Ancestry Group ,0303 health sciences ,education.field_of_study ,Genetic diversity ,Principal Component Analysis ,Base Sequence ,Geography ,Models, Genetic ,Human migration ,business.industry ,Genome, Human ,030305 genetics & heredity ,High-Throughput Nucleotide Sequencing ,Markov Chain ,Biological Evolution ,Markov Chains ,Haplotypes ,Evolutionary biology ,Homo sapiens ,Human genome ,Egypt ,Ethiopia ,business ,Human - Abstract
The predominantly African origin of all modern human populations is well established, but the route taken out of Africa is still unclear. Two alternative routes, via Egypt and Sinai or across the Bab el Mandeb strait into Arabia, have traditionally been proposed as feasible gateways in light of geographic, paleoclimatic, archaeological, and genetic evidence. Distinguishing among these alternatives has been difficult. We generated 225 whole-genome sequences (225 at 8× depth, of which 8 were increased to 30×; Illumina HiSeq 2000) from six modern Northeast African populations (100 Egyptians and five Ethiopian populations each represented by 25 individuals). West Eurasian components were masked out, and the remaining African haplotypes were compared with a panel of sub-Saharan African and non-African genomes. We showed that masked Northeast African haplotypes overall were more similar to non-African haplotypes and more frequently present outside Africa than were any sets of haplotypes derived from a West African population. Furthermore, the masked Egyptian haplotypes showed these properties more markedly than the masked Ethiopian haplotypes, pointing to Egypt as the more likely gateway in the exodus to the rest of the world. Using five Ethiopian and three Egyptian high-coverage masked genomes and the multiple sequentially Markovian coalescent (MSMC) approach, we estimated the genetic split times of Egyptians and Ethiopians from non-African populations at 55,000 and 65,000 years ago, respectively, whereas that of West Africans was estimated to be 75,000 years ago. Both the haplotype and MSMC analyses thus suggest a predominant northern route out of Africa via Egypt.
- Published
- 2015
10. Averting MERS-Cov Emerging Threat and Epidemics: The Importance of Community Alertness and Preparedness Policies and Programs
- Author
-
Ernest Tambo, Emad I.M. Khater, Zhou XiaoNong, Olalubi A. Oluwasogo, and Tamiru Oljira
- Subjects
Community resilience ,medicine.medical_specialty ,Economic growth ,business.industry ,Public health ,Humanitarian crisis ,Outbreak ,Public relations ,Resilience (organizational) ,One Health ,Preparedness ,Global health ,medicine ,business - Abstract
Africa being part of the global village is challenged by unprecedented and persistent emerging infectious diseases threats and outbreaks. Recent memories of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) outbreaks in Saudi Arabia (2012) and South Korea (2015), West Africa Ebola viral disease outbreak and public health humanitarian crisis (2014) and China’s SARS outbreaks. Various differences and similarities between these diseases have triggered serious concerns and magnified that similar outbreaks could occur anywhere in the world with lingering health complications, socio-political and economic crises. Yet, there is dearth of knowledge on MERS-CoV reservoirs, risk factors of emergence, infectivity and transmissibility in Africa and globally. This paper highlights forward approaches and key activities to the African Union, governments and institutions and all stakeholders including public-private partnership. These play paramount roles in providing information and support to address MERS-CoV and other emerging infectious diseases research gaps, (2) promoting community alertness and resilience in preparedness, (3) fostering effective and coordinated logistics in risk communication, planning and response in MERS-CoV public mobilization literacy and awareness, advocacy and mitigation. There is an urgent need to establish an integrated and strategic evidence-based local and nationwide surveillance and response capacity, (5) better understand the MERS-CoV animal reservoir(s) and human-human infectivity and transmissibility, and (6) implement informed community-based or national threat and epidemics actionable emergency insurance facility and compensation schemes. Conclusively, improved early warning, active and integrated epidemiological and genomic surveillance indicators data gathering to inform and guide effective and community resilience capability in consolidating and upholding knowledge gains from “One Health Surveillance Network” and best practices in achieving “One Health” and global health security.
- Published
- 2015
- Full Text
- View/download PDF
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