17 results on '"Szołtysik M"'
Search Results
2. Application of aluminosilicates for mitigation of ammonia and volatile organic compound emissions from poultry manure
- Author
-
Opaliński Sebastian, Korczyński Mariusz, Szołtysik Marek, Dobrzański Zbigniew, and Kołacz Roman
- Subjects
poultry manure ,ammonia ,volatile organic compounds ,air scrubber ,aluminosilicates ,Chemistry ,QD1-999 - Published
- 2015
- Full Text
- View/download PDF
3. BIOLOGICAL ACTIVITY OF EGG-YOLK PROTEIN BY-PRODUCT HYDROLYSATES OBTAINED WITH THE USE OF NON-COMMERCIAL PLANT PROTEASE.
- Author
-
ZAMBROWICZ, A., ECKERT, E., POKORA, M., DĄBROWSKA, A., SZOŁTYSIK, M., BOBAK, Ł., TRZISZKA, T., and NOWSKA, J. CHRZA
- Subjects
- *
EGG yolk , *PUMPKINS , *HYDROLYSIS , *PLANT enzymes , *ANGIOTENSIN converting enzyme , *PROTEOLYTIC enzymes , *ANTIOXIDANTS - Abstract
Enzymatic hydrolysis leads to improved functional and biological properties of protein by-products, which can be further used as nutraceuticals and protein ingredients for food applications. The present study evaluated ACE-inhibitory, antioxidant and immunostimulating activities in hydrolysates of egg-yolk protein by-product (YP), generated during industrial process of delipidation of yolk. The protein substrate was hydrolyzed using non-commercial protease from Asian pumpkin (Cucurbita ficifolia). The reaction was conducted in 0.1 M Tris-HCl buffer (pH 8.0) at temperature of 37°C for 4 hours using different enzyme doses (100-1000 U/mg of substrate). The protein degradation was monitored by the determination of the degree of hydrolysis (DH), release of free amino groups (FAG) and by RP-HPLC. In the obtained hydrolysates we also evaluated biological activities. It was shown that the highest DH of substrate (46.6%) was obtained after 4h of reaction at the highest amount of enzyme. This hydrolysate exhibited antioxidant activity, including ferric ion reducing (FRAP) (56.41 μg Fe2+/mg), ferric ion chelating (695.76 μg Fe2+/mg) and DPPH free radical scavenging (0.89 μmol troloxeq/mg) as well as ACE-inhibitory (IC50=837.75 μg/mL) activities. The research showed improved biological properties of enzymatically modified YP by-product. [ABSTRACT FROM AUTHOR]
- Published
- 2015
4. Rectum and Bladder Toxicity in Postoperative Prostate Bed Irradiation: Dose-Volume Parameters Analysis.
- Author
-
Hasterok M, Szołtysik M, Nowicka Z, Goc B, Gräupner D, Majewski W, Rasławski K, Rajwa P, Jabłońska I, Magrowski Ł, Przydacz M, Krajewski W, Masri O, and Miszczyk M
- Abstract
Although prostate cancer treatment is increasingly effective, its toxicities pose a major concern. The aim of our study was to assess the rate of adverse events (AEs) and the prognostic value of dose-volume histogram (DVH) parameters for the occurrence of treatment toxicity in patients treated with post-prostatectomy prostate bed radiotherapy (RT). The AEs were scored according to the CTCAE v.5.0. The rectum and bladder were contoured according to the RTOG Guidelines. The DVH parameters were assessed using data exported from the ECLIPSE treatment-planning system. Genitourinary (GU) and gastrointestinal (GI) toxicity were analysed using consecutive dose thresholds for the percentage of an organ at risk (OAR) receiving a given dose and the QUANTEC dose constraints. A total of 213 patients were included in the final analysis. Acute grade 2 or higher (≥G2) GU AEs occurred in 18.7% and late in 21.3% of patients. Acute ≥G2 GI toxicity occurred in 11.7% and late ≥G2 in 11.2% of the patients. Five patients experienced grade 4 AEs. The most common adverse effects were diarrhoea, proctitis, cystitis, and dysuria. The most significant predictors of acute ≥G2 GI toxicity were rectum V47 and V46 ( p < 0.001 and p < 0.001) and rectum wall V46 ( p = 0.001), whereas the most significant predictors of late ≥G2 GI AEs were rectum wall V47 and V48 ( p = 0.019 and p = 0.021). None of the bladder or bladder wall parameters was significantly associated with the risk of acute toxicity. The minimum doses to bladder wall ( p = 0.004) and bladder ( p = 0.005) were the most significant predictors of late ≥G2 GU toxicity. Postoperative radiotherapy is associated with a clinically relevant risk of AEs, which is associated with DVH parameters, and remains even in patients who fulfil commonly accepted dose constraints. Considering the lack of survival benefit of postoperative adjuvant RT, our results support delaying treatment through an early salvage approach to avoid or defer toxicity.
- Published
- 2023
- Full Text
- View/download PDF
5. Effects of Iron Supplementation on Metabolism in Calves Receiving Whole Milk.
- Author
-
Budny-Walczak A, Śpitalniak-Bajerska K, Szołtysik M, Pogoda-Sewerniak K, and Kupczyński R
- Abstract
The objective of this study was to determine the effects of feeding a protein-iron complex (PIC) to calves. Specifically, the aim was to understand how it influences productive performance and indicators of iron metabolism, hematology and biochemical and parameters during feeding with whole milk before weaning. The study was carried out on 20 Polish Holstein Friesian calves. The calves were then divided into a control group (CON), fed with full milk (n = 10), and an experimental group (MFe), who received a PIC additive in milk at 16 g/day (n = 10). In order to determine the production parameters, the calves were weighed at the beginning (i.e., on the 7th day of life) and at the end of the experiment (42nd day of life) using an electronic platform scale. Production parameters such as average weight gain (AWG), feed conversion ratio (FCR), and growth rate (GR) were assessed. Blood was collected from an external jugular vein ( vena jugularis externa ) on the 7th, 14th, 28th, and 42nd days of life. The mean daily gains in body weight (ADG), growth rate (GR), and the feed conversion ratio were highest in the experimental group, MFe. Therefore, it can be concluded that the addition of a protein-iron complex entailed a significant impact on the iron metabolism indicators in the MFe experimental group.
- Published
- 2023
- Full Text
- View/download PDF
6. Levels of TNF-α and Soluble TNF Receptors in Normal-Weight, Overweight and Obese Patients with Dilated Non-Ischemic Cardiomyopathy: Does Anti-TNF Therapy Still Have Potential to Be Used in Heart Failure Depending on BMI?
- Author
-
Lazar-Poloczek E, Romuk E, Jacheć W, Stanek W, Stanek B, Szołtysik M, Techmański T, Hasterok M, and Wojciechowska C
- Abstract
Background. We sought to measure the levels of adipokines, TNF-α and soluble receptors (sTNFr1, sTNFr2) in heart failure patients with reduced ejection fraction (HFrEF) due to non-ischemic cardiomyopathy (nDCM). Methods. A total of 123 patients with HFrEF due to nDCM were divided into three groups according to BMI: 34 (27.6%) normal weight, 56 (45.5%) overweight and 33 (26.8%) obese. A six-minute walk test, echocardiography and right heart catheterization were performed. Serum concentrations of adiponectin, leptin, NT-proBNP, blood hemoglobin, sodium, creatinine, ALAT, AspAT, bilirubin, CRP, lipids, TNF-α, sTNFr1 and sTNFr2 receptors were measured. Results. Obese patients had the lowest NT-proBNP concentrations, significantly higher leptin levels and higher leptin/adiponectin ratios. The concentration of sTNFr1 was higher in normal-weight patients. In all groups, TNF-α concentrations correlated positively with sTNFr1 (p < 0.001). Higher levels of sTNFr1 were associated with higher sTNFr2 (p < 0.001) and CRP (p < 0.001). Moreover, the concentration of sTNFr2 positively correlated with CRP (p < 0.05) and adiponectin (p < 0.001). Levels of TNF-α were not associated with elevated CRP. Conclusion: This study demonstrated that changes in the concentrations of TNF and its receptors differ between groups of patients with different BMI. These findings suggest that the effective use of anti-TNF therapy is dependent not only on BMI, but also on concentrations of TNF-α receptors and other laboratory parameters.
- Published
- 2022
- Full Text
- View/download PDF
7. Ultra-Hypofractionated Stereotactic Body Radiotherapy for Localized Prostate Cancer: Clinical Outcomes, Patterns of Recurrence, Feasibility of Definitive Salvage Treatment, and Competing Oncological Risk.
- Author
-
Miszczyk M, Szołtysik M, Hasterok M, Goldner G, Rajwa P, Namysł-Kaletka A, Napieralska A, Kraszkiewicz M, Stąpór-Fudzińska M, Tomasik B, Woźniak G, Głowacki G, Kaminiów K, Moll M, Magrowski Ł, and Majewski W
- Abstract
A cohort of 650 patients treated for localized prostate cancer (PCa) with CyberKnife
TM ultra-hypofractionated radiotherapy between 2011 and 2018 was retrospectively analyzed in terms of survival, patterns of failure, and outcomes of second-line definitive salvage therapies. The analysis was performed using survival analysis including the Kaplan-Meier method and Cox regression analysis. At a median follow-up of 49.4 months, the main pattern of failure was local-regional failure (7.4% in low-, and 13% in intermediate/high-risk group at five years), followed by distant metastases (3.6% in low-, and 6% in intermediate/high-risk group at five years). Five-year likelihood of developing a second malignancy was 7.3%; however, in the vast majority of the cases, the association with prior irradiation was unlikely. The 5-year overall survival was 90.2% in low-, and 88.8% in intermediate/high-risk patients. The independent prognostic factors for survival included age (HR 1.1; 95% CI 1.07-1.14) and occurrence of a second malignancy (HR 3.67; 95% CI 2.19-6.15). Definitive local salvage therapies were feasible in the majority of the patients with local-regional failure, and uncommonly in patients with distant metastases, with an estimated second-line progression free survival of 67.8% at two years. Competing oncological risks and age were significantly more important for patients' survival compared to primary disease recurrence.- Published
- 2022
- Full Text
- View/download PDF
8. Psychosocial stress and cortisol stress reactivity predict breast milk composition.
- Author
-
Ziomkiewicz A, Babiszewska M, Apanasewicz A, Piosek M, Wychowaniec P, Cierniak A, Barbarska O, Szołtysik M, Danel D, and Wichary S
- Subjects
- Adult, Female, Humans, Infant, Newborn, Pregnancy, Saliva chemistry, Hydrocortisone analysis, Milk, Human chemistry, Stress, Psychological
- Abstract
We studied a sample of 146 Polish, exclusively breastfeeding mothers and their healthy born on time infants to explore the effect of perinatal psychosocial stress on breast milk composition. Maternal perinatal stress was assessed using Recent Life Changes Questionnaire summarizing stressful events from the previous six months. Stress reactivity was determined by administering the cold pressor test and measuring cortisol in saliva samples taken during the test. Breast milk sample was taken to measure energy, protein, fat, lactose, and fatty acid content. Analyses revealed that stress reactivity was positively associated with milk fat and long-chain unsaturated fatty acids and negatively associated with milk lactose. Perinatal psychosocial stress negatively affected energy density, fat as well as medium-chain and long-chain saturated fatty acids in milk. These results, together with previous studies, advocate monitoring maternal psychological status during the peripartum to promote breastfeeding and healthy infant nutrition.
- Published
- 2021
- Full Text
- View/download PDF
9. Effect of Two Combined Functional Additives on Yoghurt Properties.
- Author
-
Szołtysik M, Kucharska AZ, Dąbrowska A, Zięba T, Bobak Ł, and Chrzanowska J
- Abstract
The aim of the research was the analysis of yoghurts enriched with blue honeysuckle berries dry polyphenolic extract and new preparation of resistant starch. The additives were introduced individually at concentration 0.1% ( w/v ) and in mixture at final concentration of 0.1 and 0.2% of both components. Yogurt microflora, pH, and its physicochemical and antioxidant properties were examined over 14 days of storage under refrigerated conditions. Studies showed that both substances can be successfully used in yoghurt production. Yoghurt microflora es. S. thermophilus and Lb. delbrueckii subsp. bulgaricus counts appeared to be higher in samples supplemented with these additives comparing to control yoghurt by 3-8%. More stimulating effect on their growth, especially on S. thermophilus , revealed resistant starch. Addition of this polysaccharide improved also the rheological properties of yogurts, which showed higher viscosity than samples produced without it. Addition of honeysuckle berries preparation significantly influenced the yogurts' color, giving them deep purple color, and their antioxidant potential. During storage, contents of anthocyanin and iridoid compounds were decreasing, but antioxidant activity in the products remained stable.
- Published
- 2021
- Full Text
- View/download PDF
10. The Effect of Rosa spinosissima Fruits Extract on Lactic Acid Bacteria Growth and Other Yoghurt Parameters.
- Author
-
Szołtysik M, Kucharska AZ, Sokół-Łętowska A, Dąbrowska A, Bobak Ł, and Chrzanowska J
- Abstract
The aim of the study was to evaluate the effect of purified extract from Rosa spinosissima fruits on the quality characteristics and antioxidant properties of yoghurt. The extract, added to yoghurt at a concentration of 0.1% and 0.2%, contained high quantities of phenolic compounds and exhibited high antioxidant activity due to the presence of anthocyanins flavan-3-ols, flavonols and ellagitannins. Yoghurt physicochemical properties, microbiology and antioxidant properties were evaluated after 1, 7 and 14 days of storage at a temperature of 4 °C. The data revealed a positive influence of rose preparation on yoghurt's microflora and on its other properties. The highest count of traditional yoghurt microflora was observed in samples with 0.2% of extract. Its addition had a positive effect on the yoghurts' color, giving them a characteristic pink color of an intensity dependent on additive concentration. It also significantly affected the yoghurts' antioxidant properties, which were stable during storage, as well as the content of the introduced phenolic compounds.
- Published
- 2020
- Full Text
- View/download PDF
11. Reduced IgE and IgG antigenic response to milk proteins hydrolysates obtained with the use of non-commercial serine protease from Yarrowia lipolytica.
- Author
-
Dąbrowska A, Bajzert J, Babij K, Szołtysik M, Stefaniak T, Willak-Janc E, and Chrzanowska J
- Subjects
- Allergens immunology, Allergens metabolism, Animals, Caseins immunology, Caseins metabolism, Child, Preschool, Enzyme-Linked Immunosorbent Assay, Epitopes, Female, Goats immunology, Humans, Immunoglobulin E immunology, Immunoglobulin E metabolism, Immunoglobulin G immunology, Immunoglobulin G metabolism, Milk Proteins metabolism, Protein Hydrolysates metabolism, Whey Proteins immunology, Whey Proteins metabolism, Yarrowia enzymology, Milk Hypersensitivity immunology, Milk Proteins immunology, Protein Hydrolysates immunology, Serine Proteases metabolism
- Abstract
The aim of the study was to investigate the use of serine protease from Yarrowia lipolytica yeast for reduction of milk proteins allergenicity. Whey protein concentrate (WPC-80), αs-casein and their hydrolysates were analyzed for the capacity to bind IgE and IgG antibodies present in sera from patients with cow milk protein allergy using a competitive ELISA. The hydrolysis of αs-casein and whey protein concentrate contributed to a significant reduction of their immunoreactive epitopes. In case of IgE antibodies, the lowest binding capacity was detected in the 24 h hydrolysates of both proteins in which the inhibition of the reaction was ≤20 and ≤68% for αs-casein and whey protein concentrate respectively. One hour hydrolysis of WPC-80 reduced the protein antigenicity, while the longer time (5 h) might lead to the exposure of new IgE - reactive epitopes., (Copyright © 2019. Published by Elsevier Ltd.)
- Published
- 2020
- Full Text
- View/download PDF
12. Viability and growth promotion of starter and probiotic bacteria in yogurt supplemented with whey protein hydrolysate during refrigerated storage.
- Author
-
Dąbrowska A, Babij K, Szołtysik M, and Chrzanowska J
- Subjects
- Animals, Bacteria growth & development, Dietary Supplements, Fermentation, Milk, Refrigeration, Whey Proteins, Probiotics, Protein Hydrolysates, Whey, Yogurt
- Abstract
The effect of whey protein hydrolysate (WPH) addition on growth of standard yoghurt cultures and Bifidobacterium adolescentis during co-fermentation and its viability during storage at 4ºC in yoghurts has been evaluated. WPH was obtained with the use of serine protease from Y. lipolytica yeast. Stirred probiotic yoghurts were prepared by using whole milk standardized to 16% of dry matter with the addition of either whey protein concentrate, skim milk powder (SMP), WPH-SMP (ratio 1:1), WPH. The hydrolysate increased the yoghurt culture counts at the initial stage of fermentation and significantly inhibited the decrease in population viability throughout the storage at 4ºC in comparison to the control. The post-fermentation acidification was also retarded by the addition of WPH. The hydrolysate did not increase the Bifidobacterium adolescentis counts at the initial stage. However, the WPH significantly improved its viability. After 21 days of storage, in the yogurts supplemented with WPH, the population of these bacteria oscillated around 3.04 log10 CFU/g, while in samples where SMP or whey protein concentrate was used, the bacteria were no longer detected.
- Published
- 2017
- Full Text
- View/download PDF
13. The use of serine protease from Yarrowia lipolytica yeast in the production of biopeptides from denatured egg white proteins.
- Author
-
Pokora M, Zambrowicz A, Zabłocka A, Dąbrowska A, Szołtysik M, Babij K, Eckert E, Trziszka T, and Chrzanowska J
- Subjects
- Angiotensin-Converting Enzyme Inhibitors isolation & purification, Angiotensin-Converting Enzyme Inhibitors pharmacology, Antioxidants isolation & purification, Antioxidants pharmacology, Egg Proteins drug effects, Hydrolysis, Proteolysis drug effects, Serine Proteases isolation & purification, Serine Proteases pharmacology, Yarrowia enzymology, Angiotensin-Converting Enzyme Inhibitors chemistry, Antioxidants chemistry, Egg Proteins chemistry, Peptides chemistry, Serine Proteases chemistry
- Abstract
Deriving non-conventional enzymes from cheaper sources than those used for commercially available enzymes may result in the production of hydrolysates with beneficial features, while drastically reducing the cost of hydrolysis. This is especially significant for enzymatic hydrolysis as a method of protein waste utilization. We have previously described the ability of non-commercial serine protease from Yarrowia lipolytica yeast to produce/release bioactive peptides from egg white protein by-products (EP). The enzymatic hydrolysis of EP was carried out for 24 h using the serine protease at an enzyme: substrate ratio of 1:30 (w/w). The obtained hydrolysate was characterized by protein degradation of 38% and also exhibited an antioxidant and cytokine-inducing activity. The isolation procedure (ultrafiltration and RP-HPLC) of bioactive peptides from the EP hydrolysate provided peptide fractions with significant antioxidant and ACE inhibitory activities. Three homogeneous and three heterogeneous peptide fractions were identified using MALDI-TOF/MS and the Mascot Search Results database. The peptides, mainly derived from ovalbumin, were composed of 2-19 amino-acid residues. We have thus demonstrated a novel ability of serine protease from Y. lipolytica to release biopeptides from an EP by-product.
- Published
- 2017
- Full Text
- View/download PDF
14. Hydrolysis with Cucurbita ficifolia serine protease reduces antigenic response to bovine whey protein concentrate and αs-casein.
- Author
-
Babij K, Bajzert J, Dąbrowska A, Szołtysik M, Zambrowicz A, Lubec G, Stefaniak T, Willak-Janc E, and Chrzanowska J
- Subjects
- Animals, Cattle, Hydrolysis, Immunoglobulin E chemistry, Immunoglobulin G chemistry, Antigens chemistry, Caseins chemistry, Cucurbita enzymology, Plant Proteins chemistry, Serine Proteases chemistry, Whey Proteins chemistry
- Abstract
In the present study the effect of hydrolysis with non-commercial Cucurbita ficifolia serine protease on a reduction of the IgE and IgG binding capacity of whey protein concentrate and αs-casein was investigated. The intensity of the protein degradation was analyzed by the degree of hydrolysis, the free amino groups content and RP-HPLC. The ability to bind the antibodies by native proteins and their hydrolysates was determined using a competitive ELISA test. Deep hydrolysis contributed to a significant reduction of immunoreactive epitopes present in WPC. In the case of IgE and IgG present in the serum pool of children with CMA, the lowest binding capacity was detected in the 24 h WPC hydrolysate, where the inhibition of the reaction with native WPC was ≤23 and ≤60 %, respectively. The analysis of the IgG reactivity in the antiserum of the immunized goat showed that the lowest antibody binding capacity was exhibited also by 24 h WPC hydrolysate at a concentration of 1000 μg/ml where the inhibition of the reaction with nWPC was ≤47 %. One-hour hydrolysis of α-casein was sufficient to significant reduction of the protein antigenicity, while the longer time (5 h) of hydrolysis probably lead to the appearance of new epitopes reactive with polyclonal.
- Published
- 2015
- Full Text
- View/download PDF
15. Biofortification of milk and cheese with microelements by dietary feed bio-preparations.
- Author
-
Witkowska Z, Michalak I, Korczyński M, Szołtysik M, Świniarska M, Dobrzański Z, Tuhy Ł, Samoraj M, and Chojnacka K
- Abstract
The present work reports studies on biofortification of milk and cheese with microelements. The diet of goats was supplemented with soya-based preparations with Cu(II), Fe(II), Zn(II) and Mn(II), produced by biosorption, instead of mineral salts. In innovative preparations, soya was the biological carrier of microelements. The utilitarian properties of the new preparations were tested in two groups (8 goats in each): experimental and control. The concentration of supplemented microelements was monitored in milk during the experiment. The collected milk was then used to produce cheese by enzymatic and acidic coagulation method. The effect of milk and cheese biofortification in microelements was confirmed. In milk, the level of the following microelements was higher than in the control: Cu(II) - 8.2 %, Mn(II) - 29.2 %, Zn(II) - 14.6 %. In cheese the content of Zn(II) obtained in enzymatic (19.8 %) and in acidic (120 %) coagulation was higher when compared to the control group. By using bio-preparations with microelements it was possible to produce new generation of functional food biofortified with microelements, by agronomic, and thus sustainable and ethically acceptable way. Biofortified milk and cheese can be used as designer milk to prevent from micronutrient deficiencies. Graphical Abstractᅟ.
- Published
- 2015
- Full Text
- View/download PDF
16. Multifunctional peptides derived from an egg yolk protein hydrolysate: isolation and characterization.
- Author
-
Zambrowicz A, Pokora M, Setner B, Dąbrowska A, Szołtysik M, Babij K, Szewczuk Z, Trziszka T, Lubec G, and Chrzanowska J
- Subjects
- Animals, Chickens, Free Radical Scavengers isolation & purification, Glycoside Hydrolase Inhibitors isolation & purification, Peptides isolation & purification, Saccharomyces cerevisiae enzymology, Saccharomyces cerevisiae Proteins antagonists & inhibitors, Saccharomyces cerevisiae Proteins chemistry, alpha-Glucosidases chemistry, Egg Proteins chemistry, Free Radical Scavengers chemistry, Glycoside Hydrolase Inhibitors chemistry, Peptides chemistry, Protein Hydrolysates chemistry
- Abstract
An egg yolk protein by-product following ethanol extraction of phospholipids (YP) was hydrolyzed with pepsin to produce and identify novel peptides that revealed antioxidant, ACE inhibitory and antidiabetic (α-glucosidase and DPP-IV inhibitory) activities. The peptic hydrolysate of YP was fractionated by ion-exchange chromatography and reversed-phase high-pressure liquid chromatography. Isolated peptides were identified using mass spectrometry (MALDI-ToF) and the Mascot Search Results database. Four peptides of MW ranging from 1,210.62 to 1,677.88 Da corresponded to the fragments of Apolipoprotein B (YINQMPQKSRE; YINQMPQKSREA), Vitellogenin-2 (VTGRFAGHPAAQ) and Apovitellenin-1 (YIEAVNKVSPRAGQF). These peptides were chemically synthesized and showed antioxidant, ACE inhibitory or/and antidiabetic activities. Peptide YIEAVNKVSPRAGQF exerted the strongest ACE inhibitory activity, with IC50 = 9.4 µg/mL. The peptide YINQMPQKSRE showed the strongest DPPH free radical scavenging and DPP-IV inhibitory activities and its ACE inhibitory activity (IC50) reached 10.1 µg/mL. The peptide VTGRFAGHPAAQ revealed the highest α-glucosidase inhibitory activity (IC50 = 365.4 µg/mL). A novel nutraceutical effect for peptides from an egg yolk hydrolysate was shown.
- Published
- 2015
- Full Text
- View/download PDF
17. Egg yolk proteins and peptides with biological activity.
- Author
-
Zambrowicz A, Dąbrowska A, Bobak Ł, and Szołtysik M
- Subjects
- Food, Humans, Peptides chemistry, Peptides pharmacokinetics, Biological Availability, Egg Proteins chemistry, Egg Proteins pharmacokinetics, Protein Biosynthesis
- Abstract
Many proteins of food reveal biological activity. In the sequence of these proteins also numerous biologically active peptides are encrypted. These peptides are released during proteolysis naturally occurring in the gastrointestinal tract, food fermentation or during designed enzymatic hydrolysis in vitro. Biopeptides may exert multiple activities, affecting the cardiovascular, endocrine, nervous and immune systems. An especially rich source of bioactive proteins and biopeptides is egg. Bioactive peptides released from egg white proteins have been well described, whereas egg yolk proteins as precursors of biopeptides are less well characterized. This manuscript describes biologically active proteins and peptides originating from egg yolk and presents their potential therapeutic role.
- Published
- 2014
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.