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41 results on '"Stulting, R. Doyle"'

1. A Randomized Trial of Topical Fibrinogen-Depleted Human Platelet Lysate Treatment of Dry Eye Secondary to Chronic Graft-versus-Host Disease

Author

Sugar, Alan, Mian, Shahzad, Shtein, Roni, Soong, H. Kaz, Hussain, Munira, Chamberlain, Winston, Nanji, Afshan, Clements, John, Maykovski, Jennifer, Labadzinzki, Paula Cisternas, Dana, Reza, Jin, Jia, Ciolino, Joseph, Caccaviello, John, Kelly, D. Patrick, Habibi, Roya, Ta, Christopher, Yu, Charles, Lin, Charles, Hirabayashi, Kristin, Valerio, Gabriel, Kawale, Supriya, Nunez, Mariana, Irvine, John, Lee, Olivia, Chu, Matthew, Daluvoy, Melissa, Perez, Victor, Balajonda, Elmer, Hawks, Terry, Olson, Joshua, Maltry, Amanda, Hou, Joshua, Elasky, Wendy, Jhanji, Vishal, Carla Aubourg, Rose, Stulting, R. Doyle, Waller, Edmund, Jagirdar, Neera, Walts, Terence, Kelly, David Patrick, Walts, Terence A., Stulting, Robert Doyle, and Waller, Edmund K.

Published
2022
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5. Combined Corneal Cross Linking and Other Procedures: Indications and Application Models

Author

Cummings, Arthur B., Sinjab, Mazen M., Hatch, Kathryn M., Talamo, Jonathan, Randleman, Bradley, Kanellopoulos, Anastasios John, Asimellis, George, Sakla, Hani, Altroudi, Wassim, Rabinowitz, Yaron S., Kılıç, Aylin, Rubinfeld, Roy Scott, Ambrósio Junior, Renato, El-Kateb, Mohamed, DeVore, Dale P., Ross, Michael A., De Woolfson, Bruce H., Dryjski, Olivia, Stulting, R. Doyle, Sinjab, Mazen M., editor, and Cummings, Arthur B., editor

Published
2017
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13. Results of the United States Food and Drug Administration Clinical Trial of the CustomFlex Artificial Iris

Author

Ayres, Brandon D., primary, Fant, Barbara S., additional, Landis, Zachary C., additional, Miller, Kevin M., additional, Stulting, R. Doyle, additional, Cionni, Robert J., additional, Fram, Nicole R., additional, Hamilton, Stephen, additional, Hardten, David R., additional, Koch, Douglas D., additional, Masket, Samuel, additional, Price, Francis W., additional, Rosenthal, Kenneth J., additional, Hamill, M. Bowes, additional, and Snyder, Michael E., additional

Published
2022
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14. Effect of Cornea Preservation Time on Success of Descemet Stripping Automated Endothelial Keratoplasty: A Randomized Clinical Trial

Author

Rosenwasser, George O., Szczotka-Flynn, Loretta B., Ayala, Allison R., Liang, Wendi, Aldave, Anthony J., Dunn, Steven P., McCall, Tyrone, Navarro, Lisa C., Pramanik, Sudeep, Ross, Kevin W., Stulting, R. Doyle, Terry, Mark A., Tu, Elmer Y., Verdier, David D., Kollman, Craig, Gal, Robin L., Beck, Roy W., and Lass, Jonathan H.

Published
2017
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15. Combined Corneal Cross Linking and Other Procedures: Indications and Application Models

Author

Cummings, Arthur B., primary, Sinjab, Mazen M., additional, Hatch, Kathryn M., additional, Talamo, Jonathan, additional, Randleman, Bradley, additional, Kanellopoulos, Anastasios John, additional, Asimellis, George, additional, Sakla, Hani, additional, Altroudi, Wassim, additional, Rabinowitz, Yaron S., additional, Kılıç, Aylin, additional, Rubinfeld, Roy Scott, additional, Ambrósio Junior, Renato, additional, El-Kateb, Mohamed, additional, DeVore, Dale P., additional, Ross, Michael A., additional, De Woolfson, Bruce H., additional, Dryjski, Olivia, additional, and Stulting, R. Doyle, additional

Published
2016
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18. Tipping points: topography-guided ablation reshaping refractive surgery

Author

Stulting, R. Doyle, Slade, Stephen, Stonecipher, Karl, Durrie, Daniel, and Gordon, Michael

Subjects
Laser in situ keratomileusis -- Research, Eye -- Refractive errors -- Surgery, Health
Abstract

Anyone who has read Malcolm Gladwell's book, The Tipping Point, is familiar with how a small change gains momentum to create a paradigm shift. Refractive surgeons in the United States [...]

Published
2015

21. Topography-Guided Refractive Astigmatism Outcomes: Predictions Comparing Three Different Programming Methods

Author

Stulting,R Doyle, Durrie,Daniel S, Potvin,Richard J, Linn,Steve H, Krueger,Ronald R, Lobanoff,Mark C, Moshirfar,Majid, Motwani,Manoj V, Lindquist,Timothy P, and Stonecipher,Karl G

Subjects
Clinical Ophthalmology
Abstract

R Doyle Stulting,1 Daniel S Durrie,2 Richard J Potvin,3 Steve H Linn,4 Ronald R Krueger,5 Mark C Lobanoff,6 Majid Moshirfar,4,7 Manoj V Motwani,8 Timothy P Lindquist,2 Karl G Stonecipher9 1Woolfson Eye Institute, Atlanta, GA, USA; 2DurrieVision, Kansas City, KS, USA; 3Science in Vision, Akron, NY, USA; 4Hoopes, Durrie, Rivera Research, Draper, UT, USA; 5Cleveland Clinic, Cleveland, OH, USA; 6North Suburban Eye Specialists, Minneapolis, MN, USA; 7John A. Moran Eye Center, University of Utah, Salt Lake City, UT, USA; 8Motwani LASIK Institute, San Diego, CA, USA; 9TLC Laser Centers, Greensboro, NC, USACorrespondence: R Doyle Stulting 224 Konawa LN, Loudon, TN 37774, USATel +1 770-804-1684Email ophtrds@emory.eduPurpose: To identify the laser programming strategy that will achieve optimal refractive outcomes of LASIK with a topography-guided laser for eyes with a disparity between cylinder measured by manifest refraction and cylinder measured by topography.Setting: Six surgeons at 5 clinical sites in the USA.Design: Retrospective data review.Methods: Preoperative, treatment, and postoperative data on 52 eyes that underwent topography-guided LASIK with the WaveLight EX500 Contoura® Vision excimer laser ablation profile in which the vectors representing the preoperative refractive cylinder and the cylinder measured by the WaveLight® Topolyzer™ VARIO Diagnostic Device (Vario cylinder) differed by >/= 0.50D and/or >/= 10 degrees of orientation were analyzed retrospectively. Data were contributed by six surgeons using the laser at 5 different clinical sites. Vector analysis of postoperative cylindrical refractive error and the actual laser programming strategy was used to calculate the cylindrical correction that would, theoretically, have completely eliminated postoperative refractive cylinder. This was compared to expected results using the preoperative manifest cylinder, the topographic cylinder, and the Phorcides Analytic Engine (Phorcides LLC, North Oaks MN; Phorcides). For analysis, subjects were stratified on the basis of the vector difference between Manifest and Topo cylinder (High, > 0.75 D; and Low, ≤ 0.75 D).Results: The poorest calculated theoretical outcomes were obtained with the manifest refraction (centroid: − 0.43, 0.22; mean calculated error vector: 0.56 ± 0.42 D; p=ns). Better outcomes were obtained with the topographically measured refraction (centroid: 0.37, 0.02; mean calculated error vector: 0.47 ± 0.33 D; p=ns). The best outcomes were obtained with Phorcides (centroid: − 0.15, 0.06; mean calculated error vector: 0.39 ± 0.28 D; p=ns). The mean error vector magnitude in the Phorcides Low group was significantly lower than for the Manifest and Topo Low groups (0.26 D vs 0.48 D and 0.33 D; p< 0.01). The mean error magnitude in the Phorcides High group was nearly 0.25 D lower than for the Manifest High group (0.48 D vs 0.70 D; p< 0.01), but was the same as for the Topo High group (0.48 D vs 0.48 D).Conclusion: Our study suggests that using the topographically measured cylinder or the cylinder selected by Phorcides will produce more desirable refractive outcomes than entry of the preoperative refractive cylinder as the basis for correction of myopia and myopic astigmatism with the WaveLight Contoura Vision excimer laser.Keywords: LASIK, topography, excimer, laser, PRK, astigmatism

Published
2020

23. Herpetic Eye Disease Study

Author

Wilhelmus, Kirk R., primary, Gee, Lauren, additional, Hauck, Walter W., additional, Kurinij, Natalie, additional, Dawson, Chandler R., additional, Jones, Dan B., additional, Barron, Bruce A., additional, Kaufman, Herbert E., additional, Sugar, Joel, additional, Hyndiuk, Robert A., additional, Laibson, Peter R., additional, Stulting, R. Doyle, additional, and Asbell, Penny A., additional

Published
2020
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25. Factors Associated With Graft Rejection in the Cornea Preservation Time Study

Author

Stulting, R. Doyle, primary, Lass, Jonathan H., additional, Terry, Mark A., additional, Benetz, Beth Ann, additional, Cohen, Nathan J., additional, Ayala, Allison R., additional, Maguire, Maureen G., additional, Croasdale, Christopher, additional, Daoud, Yassine J., additional, Dunn, Steven P., additional, Goins, Kenneth M., additional, Gupta, Pankaj C., additional, Macsai, Marian S., additional, Mian, Shahzad I., additional, Pramanik, Sudeep, additional, Rose-Nussbaumer, Jennifer, additional, Song, Jonathan C., additional, Stark, Walter J., additional, Sugar, Alan, additional, Verdier, David D., additional, and Szczotka-Flynn, Loretta B., additional

Published
2018
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26. Donor, Recipient, and Operative Factors Associated with Graft Success in the Cornea Preservation Time Study

Author

Terry, Mark A., primary, Aldave, Anthony J., additional, Szczotka-Flynn, Loretta B., additional, Liang, Wendi, additional, Ayala, Allison R., additional, Maguire, Maureen G., additional, Croasdale, Christopher, additional, Daoud, Yassine J., additional, Dunn, Steven P., additional, Hoover, Caroline K., additional, Macsai, Marian S., additional, Mauger, Thomas F., additional, Pramanik, Sudeep, additional, Rosenwasser, George O.D., additional, Rose-Nussbaumer, Jennifer, additional, Stulting, R. Doyle, additional, Sugar, Alan, additional, Tu, Elmer Y., additional, Verdier, David D., additional, Yoo, Sonia H., additional, and Lass, Jonathan H., additional

Published
2018
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28. Addendum

Author

Hersh, Peter S., primary, Stulting, R. Doyle, additional, Muller, David, additional, Durrie, Daniel S., additional, and Rajpal, Rajesh K., additional

Published
2018
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30. U.S. Multicenter Clinical Trial of Corneal Collagen Crosslinking for Treatment of Corneal Ectasia after Refractive Surgery

Author

Hersh, Peter S., primary, Stulting, R. Doyle, additional, Muller, David, additional, Durrie, Daniel S., additional, Rajpal, Rajesh K., additional, Binder, Perry S., additional, Donnenfeld, Eric D., additional, Durrie, Daniel, additional, Hardten, David, additional, Hersh, Peter, additional, Price, Francis, additional, Randleman, J. Bradley, additional, Schanzlin, David, additional, Stark, Walter, additional, Trattler, William, additional, and Trokel, Steven, additional

Published
2017
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31. United States Multicenter Clinical Trial of Corneal Collagen Crosslinking for Keratoconus Treatment

Author

Hersh, Peter S., primary, Stulting, R. Doyle, additional, Muller, David, additional, Durrie, Daniel S., additional, Rajpal, Rajesh K., additional, Binder, Perry S., additional, Donnenfeld, Eric D., additional, Durrie, Daniel, additional, Hardten, David, additional, Hersh, Peter, additional, Price, Francis, additional, Schanzlin, David, additional, Stark, Walter, additional, Trattler, William, additional, and Trokel, Steven, additional

Published
2017
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32. Reply

Author

Stulting, R. Doyle, Trattler, William B., Woolfson, Jonathan M., and Rubinfeld, Roy S.

Published
2019
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34. Moulds associated with contaminated ocular and injectable drugs: FDA recalls, epidemiology considerations, drug shortages, and aseptic processing.

Author

Ahearn, Donald G and Stulting, R Doyle

Abstract

Recent (2012) grave but rare outbreaks of fungal meningitis and endophthalmitis associated with drugs contaminated with select environmental moulds (Exserohilum and Fusarium, respectively) have exacerbated mycology concerns for formulation, good laboratory practices (GLP), and use of the final drug product. Intensified investigations (2013–2015) by the Food and Drug Administration (FDA) that included added responsibilities for specialty compounding laboratories have prompted at least nine voluntary mould-related drug recalls during 2014–2015. Both primary manufactures (five recalls, two companies) and secondary-processing compound laboratories (at least eight recalls, six companies) and near 0.8 million units were involved. These constituted minor fractions of recalled drug products in an estimated 2500 recalls among other causes during this time period. Recalls of similar drugs in 2016 were indirectly related to fungi. None of the mould-related- drug-recall episodes during 2014–2016 have been identified with fungal disease outbreaks. The recalls included drugs in short supply worldwide such as injectable sodium chloride- and related saline solutions as well as ocular formulations. Insufficient environmental monitoring and GLP compliance, particularly for aseptic processing of non-preserved formulations, appeared to be underlying factors in the fungal contaminations. Observations of mould growth in drugs during their processing should be accurately recorded and investigated; cryptic listings under "particulate" designations should be avoided. Confirmed identifications for chronic contaminants are recommended. Heat-tolerant moulds with resistant morphotypes are prime concerns. [ABSTRACT FROM AUTHOR]

Published
2018
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38. Complications Related to a Cosmetic Eye-Whitening Procedure

Author

Vo, Rosalind C., primary, Stafeeva, Ksenia, additional, Aldave, Anthony J., additional, Stulting, R. Doyle, additional, Moore, Quianta, additional, Pflugfelder, Stephen C., additional, Chungfat, Neil C., additional, Holsclaw, Douglas S., additional, Margolis, Todd P., additional, and Deng, Sophie X., additional

Published
2014
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39. Results of topography-guided laser in situ keratomileusis custom ablation treatment with a refractive excimer laser.

Author

Stulting, R. Doyle and Fant, Barbara S.

Subjects
*LASIK, *CORNEAL topography, *MYOPIA treatment, *ASTIGMATISM, *VISUAL acuity, *CLINICAL trials, *THERAPEUTICS
Abstract

Purpose To evaluate the safety and effectiveness of topography-guided custom ablation treatment (T-CAT) to correct myopia and myopic astigmatism with laser in situ keratomileusis (LASIK). Setting Nine clinical sites in the USA. Design Prospective observational nonrandomized unmasked study. Methods The study comprised patients aged 18 to 65 years old with myopia or myopic astigmatism with a manifest refraction spherical equivalent (MRSE) up to −9.0 diopters (D) and astigmatism of 6.0 D or less. Patients with previous refractive surgery or abnormal topography were excluded. Corneal topographies were obtained using the Allegro Topolyzer, and laser treatment was delivered with the Allegretto Wave Eye-Q excimer laser system. Visual outcomes were evaluated postoperatively at 1 day, 1 week, and 1, 3, 6, 9, and 12 months. Results The clinical trial enrolled 212 patients (249 eyes). The T-CAT procedure significantly reduced the MRSE and cylinder, with stability of outcomes evident from 3 to 12 months after surgery. Compared with the preoperative corrected distance visual acuity (CDVA), the postoperative uncorrected distance visual acuity (UDVA) improved by 1 line or more in 30% of eyes and the postoperative UDVA was at least as good as the preoperative CDVA in 90% of eyes. Most visual symptoms improved after T-CAT. There were no significant treatment-related adverse events or loss of vision. Conclusion The T-CAT procedure performed with the diagnostic device and the refractive excimer laser system safely and effectively achieved predictable refractive outcomes and reduced visual symptoms with stable results through 12 months. Financial Disclosure Dr. Stulting is a paid consultant to Alcon Laboratories, Inc., and was a medical monitor for the U.S. Food and Drug Administration (FDA) clinical trial. Dr. Fant is president of Clinical Research Consultants, Inc. (CRC), the clinical and regulatory consulting group that sponsored the FDA clinical trial. Dr. Fant and CRC were supported by Alcon Laboratories, Inc. [ABSTRACT FROM AUTHOR]

Published
2016
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40. Clinicians' Corner.

Author

Güell, José L. and Stulting, R. Doyle

Subjects
*OPHTHALMOLOGY, *SURGICAL complications, *EYE diseases
Published
2015

41. A mathematical model to predict endothelial cell density following penetrating keratoplasty with selective dropout from graft failure.

Author

Riddlesworth TD, Kollman C, Lass JH, Patel SV, Stulting RD, Benetz BA, Gal RL, and Beck RW

Subjects
Adult, Aged, Aged, 80 and over, Cell Count, Female, Follow-Up Studies, Fuchs' Endothelial Dystrophy pathology, Graft Survival, Humans, Male, Middle Aged, Postoperative Period, Retrospective Studies, Tissue Donors, Bayes Theorem, Endothelium, Corneal pathology, Fuchs' Endothelial Dystrophy surgery, Keratoplasty, Penetrating methods
Abstract

Purpose: We constructed several mathematical models that predict endothelial cell density (ECD) for patients after penetrating keratoplasty (PK) for a moderate-risk condition (principally Fuchs' dystrophy or pseudophakic/aphakic corneal edema)., Methods: In a subset (n = 591) of Cornea Donor Study participants, postoperative ECD was determined by a central reading center. Various statistical models were considered to estimate the ECD trend longitudinally over 10 years of follow-up. A biexponential model with and without a logarithm transformation was fit using the Gauss-Newton nonlinear least squares algorithm. To account for correlated data, a log-polynomial model was fit using the restricted maximum likelihood method. A sensitivity analysis for the potential bias due to selective dropout was performed using Bayesian analysis techniques., Results: The three models using a logarithm transformation yield similar trends, whereas the model without the transform predicts higher ECD values. The adjustment for selective dropout turns out to be negligible. However, this is possibly due to the relatively low rate of graft failure in this cohort (19% at 10 years). Fuchs' dystrophy and pseudophakic/aphakic corneal edema (PACE) patients had similar ECD decay curves, with the PACE group having slightly higher cell densities by 10 years., Conclusions: Endothelial cell loss after PK can be modeled via a log-polynomial model, which accounts for the correlated data from repeated measures on the same subject. This model is not significantly affected by the selective dropout due to graft failure. Our findings warrant further study on how this may extend to ECD following endothelial keratoplasty., (© ARVO.)

Published
2014
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