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Your search keyword '"Song, F. B."' showing total 7 results
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7 results on '"Song, F. B."'

1. Efficient and robust analysis of complex scattering data under noise in microwave resonators

Author

Probst, S., Song, F. B., Bushev, P. A., Ustinov, A. V., and Weides, M.

Subjects
Condensed Matter - Superconductivity, Physics - Instrumentation and Detectors
Abstract

Superconducting microwave resonators are reliable circuits widely used for detection and as test devices for material research. A reliable determination of their external and internal quality factors is crucial for many modern applications, which either require fast measurements or operate in the single photon regime with small signal to noise ratios. Here, we use the circle fit technique with diameter correction and provide a step by step guide for implementing an algorithm for robust fitting and calibration of complex resonator scattering data in the presence of noise. The speedup and robustness of the analysis are achieved by employing an algebraic rather than an iterative fit technique for the resonance circle., Comment: 7 pages, 7 figures

Published
2014
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3. Soil microbial community and activity are affected by integrated agricultural practices in China

Author

Zhu, X. C., Sun, L. Y., Song, F. B., Liu, S. Q., Liu, Fulai, Li, X. N., Zhu, X. C., Sun, L. Y., Song, F. B., Liu, S. Q., Liu, Fulai, and Li, X. N.

Abstract

Sustainable agricultural management practices improve soil processes, prevent soil erosion and consequently enhance crop productivity. The integrated agricultural practice (IP) developed in northeast China, by altering row spacing of planting, adopting no-tillage and returning all crop residues, showed great benefit in sustaining crop yield. However, its effect on the soil microbiome remains largely elusive. This study evaluated the effect of 12-year integrated agricultural practice on the structure and activity of the soil microbial community at different soil depths in China's Mollisols zone. The experiment consisted of integrated agricultural practice and conventional practice (CP) treatments in a split-plot arrangement. The soil microbial community was characterized by MiSeq sequencing. The results showed that agricultural practices affected 12 phyla, 24 classes, 32 orders and 75 families in the bacterial community and one phyla, four classes, 12 orders and 18 families in the fungal community. Integrated agricultural practice resulted in greater bacterial richness and diversity, and increased the relative abundances of Actinobacteria, Gemmatimonadetes, Verrucomicrobia and Ascomycota, but reduced Bacteroidetes, Firmicutes and Basidiomycota in the dominant bacterial and fungal phyla. These findings suggested that integrated agricultural practice modified the soil physiochemical properties and consequently altered microbial community structure and diversity, which in turn affected soil microbial biomass and enzyme activities. These changes under integrated agricultural practice could have contributed to the enhanced crop yield, suggesting that IP is a sustainable agricultural practice. Highlights: How does soil microbial community change in the IP and CP soils? IP affected the soil microbial community and activity. Bacterial and fungal community structure correlated significantly with soil physiochemical properties. IP is a promising sustainable agricultural pra

Published
2018

7. [Clinical value of p16 INK4a immunocytochemistry in cervical cancer screening].

Author

Song FB, Du H, Xiao AM, Wang C, Huang X, Yan PS, Liu ZH, Qu XF, Belinson JEROMEL, and Wu RF

Subjects
Adult, Aged, Biomarkers, Tumor analysis, Cyclin-Dependent Kinase Inhibitor p16 physiology, Early Detection of Cancer statistics & numerical data, Female, Human papillomavirus 16, Human papillomavirus 18, Humans, Middle Aged, Papillomaviridae genetics, Papillomaviridae isolation & purification, Papillomavirus Infections metabolism, Papillomavirus Infections virology, Pregnancy, Sensitivity and Specificity, Uterine Cervical Neoplasms metabolism, Uterine Cervical Neoplasms virology, Vaginal Smears, Uterine Cervical Dysplasia metabolism, Uterine Cervical Dysplasia virology, Cyclin-Dependent Kinase Inhibitor p16 analysis, Cyclin-Dependent Kinase Inhibitor p16 immunology, Early Detection of Cancer methods, Immunohistochemistry methods, Papillomavirus Infections diagnosis, Uterine Cervical Neoplasms diagnosis, Uterine Cervical Dysplasia diagnosis
Abstract

Objective: To evaluate the value of p16 INK4a detected by p16 INK4a immunostaining as a new generation of cervical cytology for primary screening and secondary screening in population-based cervical cancer screening, and in improving cytological diagnosis. Methods: Between 2016 and 2018, 5 747 non-pregnant women aged 25-65 years with sexual history were recruited and underwent cervical cancer screening via high-risk (HR)-HPV/liquid-based cytological test (LCT) test in Shenzhen and surrounding areas. All slides were immuno-stained using p16 INK4a technology, among them, 902 cases were offered p16 INK4a detection during primary screening, and the remaining 4 845 cases were called-back by the virtue of abnormal HR-HPV and LCT results for p16 INK4a staining. Participants with complete LCT examination, HR-HPV test, p16 INK4a staining and histopathological examination results were included in this study. The performance of p16 INK4a in primary and secondary screening, and in assisting cytology to detect high grade squamous intraepithelial lesion [HSIL, including cervical intraepithelial neoplasia (CIN) Ⅱ or Ⅲ] or worse [HSIL (CIN Ⅱ) + or HSIL (CIN Ⅲ) + ] were analyzed. Results: (1) One-thousand and ninety-seven cases with complete data of p16 INK4a and histology were included. Pathological diagnosis: 995 cases of normal cervix, 37 cases of low grade squamous intraepithelial lesion (LSIL), 64 cases of HSIL and one case of cervical cancer were found. Among them, 65 cases of HSIL (CIN Ⅱ) + and 34 cases of HSIL (CIN Ⅲ) + were detected. The positive rate of p16 INK4a in HSIL (CIN Ⅱ) + was higher than that in CINⅠ or normal pathology (89.2% vs 10.2%; P <0.01). (2) p16 INK4a as primary screening for HSIL (CIN Ⅱ) + or HSIL (CIN Ⅲ) + was equally sensitive to primary HR-HPV screening (89.2% vs 95.4%, 94.1% vs 94.1%; P >0.05), but more specific than HR-HPV screening (89.8% vs 82.5%, 87.7% vs 80.2%; P <0.05). p16 INK4a was equally sensitive and similarly specific to cytology (≥LSIL; P >0.05). (3) The specificity of LCT adjunctive p16 INK4a for detecting HSIL (CIN Ⅱ) + or HSIL (CIN Ⅲ) + were higher than that of LCT alone or adjunctive HR-HPV ( P <0.01), while the sensitivity were similar ( P >0.05). (4) p16 INK4a staining as secondary screening: p16 INK4a was significantly more specific (94.1% vs 89.7%, 91.9% vs 87.4%; P <0.01) and comparably sensitive (84.6% vs 90.8%, 88.2% vs 91.2%; P >0.05) to cytology for triaging primary HR-HPV screening. HPV 16/18 to colposcopy and triage other HR-HPV with p16 INK4a was equally sensitive (88.2% vs 94.1%; P =0.500) and more specific (88.3% vs 83.0%; P <0.01) than HPV 16/18 to colposcopy and triage other HR-HPV with LCT≥ atypical squamous cells of undetermined significance (ASCUS), and the referral rate decreased (14.0% vs 19.4%; P =0.005). Conclusions: For primary screening, p16 INK4a is equally specific to cytology and equally sensitive to HR-HPV screening. p16 INK4a alone could be an efficient triage after primary HR-HPV screening. In addition, p16 INK4a immunostaining could be used as an ancillary tool to cervical cytological diagnosis, and improves its accuracy in cervical cancer screening.

Published
2020
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