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Your search keyword '"Shi, Zhi-Jun"' showing total 7 results
Start Over Author "Shi, Zhi-Jun" Publication Year Range Last 10 years
7 results on '"Shi, Zhi-Jun"'

3. List of contributors

Author

Ahearne, Mark, primary, Gao, Xing, additional, Goh, K.B., additional, Islam, Mohammad R., additional, Jincheng Lei, J., additional, Li, Hua, additional, Li, Ziqian, additional, Liu, Qimin, additional, Liu, Zishun, additional, Lu, Tongqing, additional, Ma, Lianhua, additional, Miao, Yinggang, additional, Oyen, Michelle L., additional, Shi, Zhi-Jun, additional, Silberschmidt, Vadim V., additional, Sozumert, Emrah, additional, Toh, William, additional, Wang, Xingquan, additional, Wu, Tao, additional, Xu, Shuai, additional, Yang, Qingsheng, additional, Zhang, Jianxun, additional, Zhang, Qiang, additional, Zhang, Wenlei, additional, Zhao, Wei-Wei, additional, Zheng, Shoujing, additional, and Zhou, Yifan, additional

Published
2022
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7. Comparison of the analgesic effects between electro-acupuncture and moxibustion with visceral hypersensitivity rats in irritable bowel syndrome.

Author

Zhao JM, Li L, Chen L, Shi Y, Li YW, Shang HX, Wu LY, Weng ZJ, Bao CH, and Wu HG

Subjects
Abdominal Pain diagnosis, Abdominal Pain metabolism, Abdominal Pain physiopathology, Animals, Colon metabolism, Disease Models, Animal, Hyperalgesia diagnosis, Hyperalgesia metabolism, Hyperalgesia physiopathology, Irritable Bowel Syndrome diagnosis, Irritable Bowel Syndrome metabolism, Irritable Bowel Syndrome physiopathology, Male, Mast Cells metabolism, Pain Measurement, Posterior Horn Cells metabolism, Rats, Sprague-Dawley, Receptors, Serotonin, 5-HT3 metabolism, Receptors, Serotonin, 5-HT4 metabolism, Serotonin metabolism, Temperature, Visceral Pain diagnosis, Visceral Pain metabolism, Visceral Pain physiopathology, Abdominal Pain therapy, Colon innervation, Electroacupuncture, Hyperalgesia therapy, Irritable Bowel Syndrome therapy, Moxibustion, Pain Management methods, Visceral Pain therapy
Abstract

Aim: To observe whether there are differences in the effects of electro-acupuncture (EA) and moxibustion (Mox) in rats with visceral hypersensitivity., Methods: EA at 1 mA and 3 mA and Mox at 43 °C and 46 °C were applied to the Shangjuxu (ST37, bilateral) acupoints in model rats with visceral hypersensitivity. Responses of wide dynamic range neurons in dorsal horns of the spinal cord were observed through the extracellular recordings. Mast cells (MC) activity in the colons of rats were assessed, and 5-hydroxytryptamine (5-HT), 5-hydroxytryptamine 3 receptor (5-HT3R) and 5-HT4R expressions in the colons were measured., Results: Compared with normal control group, responses of wide dynamic range neurons in the dorsal horn of the spinal cord were increased in the EA at 1 mA and 3 mA groups (1 mA: 0.84 ± 0.74 vs 2.73 ± 0.65, P < 0.001; 3 mA: 1.91 ± 1.48 vs 6.44 ± 1.26, P < 0.001) and Mox at 43 °C and 46 °C groups (43 °C: 1.76 ± 0.81 vs 4.14 ± 1.83, P = 0.001; 46 °C: 5.19 ± 2.03 vs 7.91 ± 2.27, P = 0.01). MC degranulation rates and the expression of 5-HT, 5-HT3R and 5-HT4R in the colon of Mox 46 °C group were decreased compared with model group (MC degranulation rates: 0.47 ± 0.56 vs 0.28 ± 0.78, P < 0.001; 5-HT: 1.42 ± 0.65 vs 7.38 ± 1.12, P < 0.001; 5-HT3R: 6.62 ± 0.77 vs 2.86 ± 0.88, P < 0.001; 5-HT4R: 4.62 ± 0.65 vs 2.22 ± 0.97, P < 0.001)., Conclusion: The analgesic effects of Mox at 46 °C are greater than those of Mox at 43 °C, EA 1 mA and EA 3 mA., Competing Interests: Conflict-of-interest statement: The authors declare no conflict of interest related to this study.

Published
2017
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