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Your search keyword '"Sensini, L."' showing total 12 results
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12 results on '"Sensini, L."'

11. Hierarchical electrospun tendon/ligament-inspired scaffolds can modify fibroblasts morphology in static and dynamic cultures

Author

A. Sensini, L. Cristofolini, A. Zucchelli, M. L. Focarete, C. Gualandi, M. Fichera, A. De Mori, A. P. Kao, M. Roldo, G. Blunn, G. Tozzi, and A. Sensini, L. Cristofolini, A. Zucchelli, M. L. Focarete, C. Gualandi, M. Fichera, A. De Mori, A. P. Kao, M. Roldo, G. Blunn, G. Tozzi

Subjects
Hierarchical electrospun scaffolds, Dynamic cell cultures, X-ray computed tomography, Tendons and ligaments regeneration
Abstract

The morphological arrangement of scaffold is fundamental to drive cell growth and regeneration of collagen extracellular matrix. Electrospinning is a very promising technique to produce nanofibrous scaffolds able to guide cells in the regeneration of injured tissues. We developed a resorbable electrospun scaffold mimicking the hierarchical structure of tendons and ligaments. The aim of the present study was to investigate if hierarchically structured poly(L-lactic acid) (PLLA) and collagen (Coll) electrospun scaffolds can induce morphological modifications in human fibroblasts, while cultured in static and dynamic conditions. Different imaging techniques such as high-resolution x-ray computed tomography (XCT), scanning electron microscopy (SEM), fluorescence microscopy and histology were combined to assess the potential of such scaffolds.

Published
2019

12. High-resolution x-ray tomographic characterization of hierarchical multiscale nanofibrous scaffolds for tendon tissue regeneration

Author

Alberto Sensini, Luca Cristofolini, Maria Letizia Focarete, chiara gualandi, Juri Belcari, Andrea Zucchelli, Kao, A. P., Boyle, L., Reilly, G., Tozzi, G., and A. Sensini, L. Cristofolini, M. L. Focarete, C. Gualandi, J. Belcari, A. Zucchelli, A. P. Kao, L. Boyle, G. Reilly, G. Tozzi

Subjects
Electrospinning, multiscale scaffolds, x-ray tomography, cell cultures
Published
2018

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