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180 results on '"Sato, Iori"'

1. Hagfish genome elucidates vertebrate whole-genome duplication events and their evolutionary consequences

Author

Yu, Daqi, Ren, Yandong, Uesaka, Masahiro, Beavan, Alan J. S., Muffato, Matthieu, Shen, Jieyu, Li, Yongxin, Sato, Iori, Wan, Wenting, Clark, James W., Keating, Joseph N., Carlisle, Emily M., Dearden, Richard P., Giles, Sam, Randle, Emma, Sansom, Robert S., Feuda, Roberto, Fleming, James F., Sugahara, Fumiaki, Cummins, Carla, Patricio, Mateus, Akanni, Wasiu, D’Aniello, Salvatore, Bertolucci, Cristiano, Irie, Naoki, Alev, Cantas, Sheng, Guojun, de Mendoza, Alex, Maeso, Ignacio, Irimia, Manuel, Fromm, Bastian, Peterson, Kevin J., Das, Sabyasachi, Hirano, Masayuki, Rast, Jonathan P., Cooper, Max D., Paps, Jordi, Pisani, Davide, Kuratani, Shigeru, Martin, Fergal J., Wang, Wen, Donoghue, Philip C. J., Zhang, Yong E., and Pascual-Anaya, Juan

Published
2024
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9. The Prospective Natural History Study of Patients with Intractable Venous Malformation and Klippel–Trenaunay Syndrome to Guide Designing a Proof-of-Concept Clinical Trial for Novel Therapeutic Intervention

Author

Fujino, Akihiro, primary, Kuniyeda, Kanako, additional, Nozaki, Taiki, additional, Ozeki, Michio, additional, Ohyama, Tetsuji, additional, Sato, Iori, additional, Kamibeppu, Kiyoko, additional, Tanaka, Akira, additional, Uemura, Naoto, additional, Kanmuri, Kazuhiro, additional, Nakamura, Kenji, additional, Kobayashi, Fumiaki, additional, Suenobu, Souichi, additional, Nomura, Tadashi, additional, Hayashi, Ayato, additional, Nagao, Munetomo, additional, Kato, Aiko, additional, Aramaki-Hattori, Noriko, additional, Imagawa, Kotaro, additional, Ishikawa, Kosuke, additional, Ochi, Junko, additional, Horiuchi, Saya, additional, and Nagabukuro, Hiroshi, additional

Published
2023
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12. Fact-finding survey of doctors at the departments of pediatrics and pediatric surgery on the transition of patients with childhood-onset chronic disease from pediatric to adult healthcare

Author

Kikuchi, Ryota, primary, Sato, Iori, additional, Hirata, Yoichiro, additional, Sugiyama, Masahiko, additional, Iwasaki, Miwa, additional, Sekiguchi, Hiromi, additional, Sato, Atsushi, additional, Suzuki, Seigo, additional, Morisaki-Nakamura, Mayumi, additional, Kita, Sachiko, additional, Oka, Akira, additional, Kamibeppu, Kiyoko, additional, Ikeda, Mari, additional, and Kato, Motohiro, additional

Published
2023
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16. The Prospective Natural History Study of Patients with Intractable Venous Malformation and Klippel–Trenaunay Syndrome to Guide Designing a Proof-of-Concept Clinical Trial for Novel Therapeutic Intervention.

Author

Fujino, Akihiro, Kuniyeda, Kanako, Nozaki, Taiki, Ozeki, Michio, Ohyama, Tetsuji, Sato, Iori, Kamibeppu, Kiyoko, Tanaka, Akira, Uemura, Naoto, Kanmuri, Kazuhiro, Nakamura, Kenji, Kobayashi, Fumiaki, Suenobu, Souichi, Nomura, Tadashi, Hayashi, Ayato, Nagao, Munetomo, Kato, Aiko, Aramaki-Hattori, Noriko, Imagawa, Kotaro, and Ishikawa, Kosuke

Abstract

Background: The natural history of venous malformation (VM) and Klippel–Trenaunay Syndrome (KTS) has not been quantitatively studied. To obtain benchmarks to guide designing clinical trials to assess safety and efficacy of novel drug candidates, the clinical course of the patients was followed for 6 months. Methods and Results: This is a multicenter prospective observational study evaluating the change rate in lesion volume from baseline with magnetic resonance images, as the primary endpoint. In addition, disease severities, performance status (PS), pain visual analog scale (VAS) score, quality of life (QoL), infections, and coagulation markers were also evaluated. Thirty-four patients (VM = 17, KTS = 17, 1–53 of age; median 15.9 years) with measurable lesion volume were analyzed. There was no statistically significant difference in the lesion volume between baseline and day 180, and the mean change rate (standard deviation) was 1.06 (0.28). There were no baseline characteristics that affected the change in lesion volume over 6 months. However, there were patients who showed more than 20% volume change and it was suggested that the lesion volume was largely impacted by local infection. There were no statistically significant changes in pain VAS score, severity, PS, QoL score, D-dimer, and platelet count over 6 months within all patients analyzed. Conclusion: The results showed the representative natural course of VM and KTS for a 6-month period with objective change of lesion volume and other factors, suggesting that it is scientifically reasonable to conduct a Phase 2 proof-of-concept study without a placebo arm, using the results of this study as the control. Clinical Trial Registration: NCT04285723, NCT04589650. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Hagfish genome illuminates vertebrate whole genome duplications and their evolutionary consequences

Author

Pascual-Anaya, Juan, primary, Yu, Daqi, additional, Ren, Yandong, additional, Uesaka, Masahiro, additional, Beavan, Alan, additional, Muffato, Matthieu, additional, Shen, Jieyu, additional, Li, Yongxin, additional, Sato, Iori, additional, Wan, Wenting, additional, Clark, James, additional, Keating, Joseph, additional, Carlisle, Emily, additional, Dearden, Richard, additional, Giles, Sam, additional, Randle, Emma, additional, Sansom, Robert, additional, Feuda, Roberto, additional, Fleming, James, additional, Sugahara, Fumiaki, additional, Cummins, Carla, additional, Patricio, Mateus, additional, Akanni, Wasiu, additional, D'Aniello, Salvatore, additional, Bertolucci, Cristiano, additional, Irie, Naoki, additional, Alev, Cantas, additional, Sheng, Guojun, additional, de Mendoza, Alex, additional, Maeso, Ignacio, additional, Irimia, Manuel, additional, Fromm, Bastian, additional, Peterson, Kevin, additional, Das, Sabyasachi, additional, Hirano, Masayuki, additional, Rast, Jonathan, additional, Cooper, Max, additional, Paps, Jordi, additional, Pisani, Davide, additional, Kuratani, Shigeru, additional, Martin, Fergal, additional, Wang, Wen, additional, Donoghue, Philip, additional, and Zhang, Yong, additional

Published
2023
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20. Hagfish genome illuminates vertebrate whole genome duplications and their evolutionary consequences

Author

Yu, Daqi, primary, Ren, Yandong, additional, Uesaka, Masahiro, additional, Beavan, Alan J. S., additional, Muffato, Matthieu, additional, Shen, Jieyu, additional, Li, Yongxin, additional, Sato, Iori, additional, Wan, Wenting, additional, Clark, James W., additional, Keating, Joseph N., additional, Carlisle, Emily M., additional, Dearden, Richard P., additional, Giles, Sam, additional, Randle, Emma, additional, Sansom, Robert S., additional, Feuda, Roberto, additional, Fleming, James F., additional, Sugahara, Fumiaki, additional, Cummins, Carla, additional, Patricio, Mateus, additional, Akanni, Wasiu, additional, D'Aniello, Salvatore, additional, Bertolucci, Cristiano, additional, Irie, Naoki, additional, Alev, Cantas, additional, Sheng, Guojun, additional, de Mendoza, Alex, additional, Maeso, Ignacio, additional, Irimia, Manuel, additional, Fromm, Bastian, additional, Peterson, Kevin J., additional, Das, Sabyasachi, additional, Hirano, Masayuki, additional, Rast, Jonathan P., additional, Cooper, Max D., additional, Paps, Jordi, additional, Pisani, Davide, additional, Kuratani, Shigeru, additional, Martin, Fergal J., additional, Wang, Wen, additional, Donoghue, Philip C. J., additional, Zhang, Yong E., additional, and Pascual-Anaya, Juan, additional

Published
2023
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21. Effectiveness of a peer group-based online intervention program in empowering families of children with disabilities at home

Author

Wakimizu, Rie, Matsuzawa, Akemi, Fujioka, Hiroshi, Nishigaki, Kaori, Sato, Iori, Suzuki, Seigo, and Iwata, Naoko

Subjects
Pediatrics, Perinatology and Child Health
Abstract

BackgroundThe empowerment of families raising children with disabilities (CWD) is crucial in maintaining their health. We developed an evidence-based, family empowerment intervention program focusing on social resource utilization and reducing care burden.ObjectiveThis study aimed to determine the program's effectiveness in promoting family empowerment.MethodsWe compared an intervention group that started the online intervention program a week after initial evaluation and a group that received delayed intervention (waitlist-controlled group) at three time points: initial (T1), post-course (T2), and follow-up (T3). The required sample size was 52.ResultsThere were 60 participants who applied to the program. One participant dropped out due to scheduling issues, and the others were assigned to either the intervention group (n = 29) or the waitlist-controlled group (n = 30). Those who responded to the baseline questionnaire (T1: 26 from the intervention group; 29 from the waitlist-controlled group) comprised the final sample. Among them, 20 members of the intervention group and 20 of the waitlist-controlled group attended all four sessions (completion rates of 77% and 69%, respectively). The attendance rate for sessions 1–4 was 94%, 89%, 81%, and 83%, respectively. The participant numbers in each session ranged from 5 to 18 per month. The baseline outcome score did not differ between the groups. The primary outcome, family empowerment, measured using the family empowerment scale (FES), was significantly higher at T2 for the intervention group than in the waitlist-controlled group and was sustained in the sensitivity analysis. The intervention group's FES, in the family relationships (FA) and relationships with service systems (SS) subdomains, increased significantly, unlike involvement with the community (SP). The intervention group experienced lower care burden and higher self-compassion, especially in the isolation and over-identification items of the self-compassion scale-short form (SCS-SF). The intervention group's FES (total, FA, SS) and SCS-SF (total, common humanity, isolation) changed significantly between T1 and T2, and all, except common humanity, were sustained up to T3; this group's FES (SP) and SCS (negative score, over-identification) changed significantly between T1 and T3. The waitlist-controlled group's FES (total, FA) and SCS (total) changed significantly and were sustained between T2 and T3.ConclusionsThe developed intervention program promotes family empowerment in families of CWD.Clinical Trial RegistrationThis study is registered as a clinical trial in the UMIN Clinical Trials Registry (https://center6.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000050422, UMIN000044172).

Published
2022

23. Evolution of the nitric oxide synthase family in vertebrates and novel insights in gill development

Author

Annona, Giovanni, primary, Sato, Iori, additional, Pascual-Anaya, Juan, additional, Osca, David, additional, Braasch, Ingo, additional, Voss, Randal, additional, Stundl, Jan, additional, Soukup, Vladimir, additional, Ferrara, Allyse, additional, Fontenot, Quenton, additional, Kuratani, Shigeru, additional, Postlethwait, John H., additional, and D'Aniello, Salvatore, additional

Published
2022
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25. Peer group-based online intervention program to empower families raising children with disabilities : protocol for a feasibility study using non-randomized waitlist-controlled trial

Author

1000020382822, Matsuzawa, Akemi, 1000070510121, Wakimizu, Rie, 1000020622252, Sato, Iori, Fujioka, Hiroshi, 1000090637852, Nishigaki, Kaori, Suzuki, Seigo, Iwata, Naoko, 1000020382822, Matsuzawa, Akemi, 1000070510121, Wakimizu, Rie, 1000020622252, Sato, Iori, Fujioka, Hiroshi, 1000090637852, Nishigaki, Kaori, Suzuki, Seigo, and Iwata, Naoko

Abstract

Background Families raising children with disabilities assume risks to their health and lives. Therefore, it is necessary to support these families to improve family empowerment, which is the ability of these families to control their own lives and to promote the collaborative raising of children with disabilities. This is the first online intervention program focusing on the empowerment of families raising children with disabilities who live at home in Japan. Method The program consists of four online peer-based group sessions. Moreover, the families engage in several activities in stages wherein they discover their own issues, find measures to resolve them, and take action, while visualizing interfamily relationships, including social resources, and the status of their family life, with facilitators and other peer members. This study is a non-randomized, waitlist-controlled trial. It compares the results of the intervention group (early group) and the waitlist-controlled group (delayed group). The participants are allocated to the early or delayed group in the order of their applications. The main outcome is family empowerment. Other outcomes are the caregiver burden, self-reported capability to use social resources, self-compassion, and the quality of life (QOL) of primary caregivers. The timeline of the online outcome evaluation is as follows: the initial evaluation (Time 1 [T1]) is conducted before the start of the first early group program, and post-intervention evaluation (Time 2 [T2]) is conducted immediately (within 1 week) after the early group completes all four sessions (4 weeks) of the program. Follow-up evaluation (Time 3 [T3]) is conducted 4 weeks after the post-intervention evaluation. This timing is the same in the delayed group, but the delayed group will attend the program after a 4-week waiting period, compared to the early group. Discussion The intention is to evaluate whether the provision of the program developed in this study and the evaluati

Published
2022

28. Discontinuation of tyrosine kinase inhibitors in pediatric chronic myeloid leukemia

Author

Shima, Haruko, primary, Kada, Akiko, additional, Tanizawa, Akihiko, additional, Sato, Iori, additional, Tono, Chikako, additional, Ito, Masaki, additional, Yuza, Yuki, additional, Watanabe, Akihiro, additional, Kamibeppu, Kiyoko, additional, Uryu, Hideko, additional, Koh, Katsuyoshi, additional, Imai, Chihaya, additional, Yoshida, Nao, additional, Koga, Yuhki, additional, Fujita, Naoto, additional, Saito, Akiko M., additional, Adachi, Souichi, additional, Ishii, Eiichi, additional, and Shimada, Hiroyuki, additional

Published
2022
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30. Factors in the Establishment of a Publicly-Managed Supermarket for Improvement in Access to Food: A Case Study of Hokuryu Town in Hokkaido, Japan

Author

Sato, Iori and Shimizuike, Yoshiharu

Abstract

In recent years, more and more people especially without cars have faced difficulties in accessing to food because of store closure. This paper aims to clarify the factors in the establishment of a publiclymanaged supermarket managed by a local government in Hokkaido, Japan. The conclusions of this study are as follows. First, local government had to and could spend a huge sum of money on the new facilities of the store. Secondly, the retailer could cooperate with the town at relatively low cost with existing departments and staffs. Besides, there was no need constructing the new distribution system since the new store was going to be located on the way to the existing directly-managed stores. However, there is little room for quantitative expansion of similar measures. It is important that the residents make purchases to support the nearest shop.

Published
2020

31. Annona_procb_ESM_Supplementary Material.docx from Evolution of the nitric oxide synthase family in vertebrates and novel insights in gill development

Author

Annona, Giovanni, Sato, Iori, Pascual-Anaya, Juan, Osca, David, Braasch, Ingo, Voss, Randal, Stundl, Jan, Soukup, Vladimir, Ferrara, Allyse, Fontenot, Quenton, Kuratani, Shigeru, Postlethwait, John H., and D'Aniello, Salvatore

Abstract

Nitric oxide (NO) is an ancestral key signalling molecule essential for life and has enormous versatility in biological systems, including cardiovascular homeostasis, neurotransmission and immunity. Although our knowledge of NO synthases (Nos), the enzymes that synthesize NO in vivo, is substantial, the origin of a large and diversified repertoire of nos gene orthologues in fishes with respect to tetrapods remains a puzzle. The recent identification of nos3 in the ray-finned fish spotted gar, which was considered lost in this lineage, changed this perspective. This finding prompted us to explore nos gene evolution, surveying vertebrate species representing key evolutionary nodes. This study provides noteworthy findings: first, nos2 experienced several lineage-specific gene duplications and losses. Second, nos3 was found to be lost independently in two different teleost lineages, Elopomorpha and Clupeocephala. Third, the expression of at least one nos paralogue in the gills of developing shark, bichir, sturgeon, and gar, but not in lamprey, suggests that nos expression in this organ may have arisen in the last common ancestor of gnathostomes. These results provide a framework for continuing research on nos genes’ roles, highlighting subfunctionalization and reciprocal loss of function that occurred in different lineages during vertebrate genome duplications.

Published
2022
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33. Additional file 1 of Peer group-based online intervention program to empower families raising children with disabilities: protocol for a feasibility study using non-randomized waitlist-controlled trial

Author

Matsuzawa, Akemi, Wakimizu, Rie, Sato, Iori, Fujioka, Hiroshi, Nishigaki, Kaori, Suzuki, Seigo, and Iwata, Naoko

Abstract

Additional file 1. SPRIT 2013 Checklist: Recommended items to address in a clinical trial protocol and related documents.

Published
2022
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34. Additional file 2 of Peer group-based online intervention program to empower families raising children with disabilities: protocol for a feasibility study using non-randomized waitlist-controlled trial

Author

Matsuzawa, Akemi, Wakimizu, Rie, Sato, Iori, Fujioka, Hiroshi, Nishigaki, Kaori, Suzuki, Seigo, and Iwata, Naoko

Abstract

Additional file 2. The TIDieR (Template for Intervention Description and Replication) Checklist: Information to include when describing an intervention and the location of the information.

Published
2022
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35. Additional file 1 of Thyroid and endostyle development in cyclostomes provides new insights into the evolutionary history of vertebrates

Author

Takagi, Wataru, Sugahara, Fumiaki, Higuchi, Shinnosuke, Kusakabe, Rie, Pascual-Anaya, Juan, Sato, Iori, Oisi, Yasuhiro, Ogawa, Nobuhiro, Miyanishi, Hiroshi, Adachi, Noritaka, Hyodo, Susumu, and Kuratani, Shigeru

Subjects
endocrine system, endocrine system diseases
Abstract

Additional file 1: Fig. S1. Endostyle and thyroid glands of chordates. Fig. S2. Hagfish thyroid development described by Charles Stockard and hagfish thyroid gland development during late developmental stages. Fig. S3. Thyroid development in catshark. Fig. S4. Expression patterns of cyclostome- and lamprey-specific paralogues. Fig. S5. Molecular phylogenetic analysis of Pax2/5/8 and Hhex.

Published
2022
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39. Health-Related Quality of Life in Parents of Hospitalized Children with Cancer: Association with Changes in Working Conditions and Parental Beliefs

Author

Kobayashi, Asuka, primary, Nakajima, Shohei, additional, Sato, Iori, additional, Hiwatari, Mitsuteru, additional, Seki, Masafumi, additional, Mitani, Yuichi, additional, Hidaka, Moe, additional, Satake, Kazuyo, additional, Shimosakon, Sumi, additional, Yanagi, Masato, additional, Koh, Katsuyoshi, additional, Yuza, Yuki, additional, Takita, Junko, additional, and Kamibeppu, Kiyoko, additional

Published
2022
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40. PEDT-5 Problem for the guideline of CNS germ cell tumors

Author

Nakamura, Hideo, primary, Yanagisawa, Takaaki, additional, Soejima, Toshinori, additional, Yokoo, Hideaki, additional, Nishikawa, Ryo, additional, Fujimaki, Takamitsu, additional, Hara, Junichi, additional, Terashima, Keita, additional, Sonoda, Yukihiko, additional, Arakawa, Yoshiki, additional, Kumabe, Toshihiro, additional, Sugiyama, Kazuhiko, additional, Fukuoka, Kohei, additional, Takami, Hirokazu, additional, Sakurada, Kaori, additional, Mineharu, Yohei, additional, Fujii, Motoaki, additional, Shinojima, Naoki, additional, Yamasaki, Kai, additional, Fujimura, Junya, additional, Yamasaki, Fumiyuki, additional, Takahashi, Mayu, additional, Suzuki, Tomonari, additional, and Sato, Iori, additional

Published
2021
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44. The Japan Society for Neuro-Oncology guideline on the diagnosis and treatment of central nervous system germ cell tumors

Author

Nakamura, Hideo, primary, Takami, Hirokazu, additional, Yanagisawa, Takaaki, additional, Kumabe, Toshihiro, additional, Fujimaki, Takamitsu, additional, Arakawa, Yoshiki, additional, Karasawa, Katsuyuki, additional, Terashima, Keita, additional, Yokoo, Hideaki, additional, Fukuoka, Kohei, additional, Sonoda, Yukihiko, additional, Sakurada, Kaori, additional, Mineharu, Yohei, additional, Soejima, Toshinori, additional, Fujii, Motoaki, additional, Shinojima, Naoki, additional, Hara, Junichi, additional, Yamasaki, Kai, additional, Fujimura, Junya, additional, Yamasaki, Fumiyuki, additional, Takahashi, Mayu, additional, Suzuki, Tomonari, additional, Sato, Iori, additional, Nishikawa, Ryo, additional, and Sugiyama, Kazuhiko, additional

Published
2021
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45. Impact of chronic GVHD on QOL assessed by visual analogue scale in pediatric HSCT survivors and differences between raters: a cross-sectional observational study in Japan

Author

Hayakawa, Akira, primary, Sato, Iori, additional, Kamibeppu, Kiyoko, additional, Ishida, Yasushi, additional, Inoue, Masami, additional, Sato, Atsushi, additional, Shiohara, Masaaki, additional, Yabe, Hiromasa, additional, Koike, Kazutoshi, additional, Adachi, Souichi, additional, Atsuta, Yoshiko, additional, Yamashita, Takuya, additional, Kanda, Yoshinobu, additional, and Okamoto, Shinichiro, additional

Published
2021
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48. Evolution of the nitric oxide synthase family in vertebrates and novel insights in gill development

Author

Annona, Giovanni, Sato, Iori, Pascual-Anaya, Juan, Braasch, Ingo, Voss, Randal, Stundl, Jan, Soukup, Vladimir, Kuratani, Shigeru, Postlethwait, John H., D’Aniello, Salvatore, Annona, Giovanni, Sato, Iori, Pascual-Anaya, Juan, Braasch, Ingo, Voss, Randal, Stundl, Jan, Soukup, Vladimir, Kuratani, Shigeru, Postlethwait, John H., and D’Aniello, Salvatore

Abstract

Nitric oxide (NO) is an ancestral key signaling molecule essential for life and has enormous versatility in biological systems, including cardiovascular homeostasis, neurotransmission, and immunity. Although our knowledge of nitric oxide synthases (Nos), the enzymes that synthesize NO in vivo, is substantial, the origin of a large and diversified repertoire of nos gene orthologs in fish with respect to tetrapods remains a puzzle. The recent identification of nos3 in the ray-finned fish spotted gar, which was considered lost in the ray-finned fish lineage, changed this perspective. This prompted us to explore nos gene evolution and expression in depth, surveying vertebrate species representing key evolutionary nodes. This study provides noteworthy findings: first, nos2 experienced several lineage-specific gene duplications and losses. Second, nos3 was found to be lost independently in two different teleost lineages, Elopomorpha and Clupeocephala. Third, the expression of at least one nos paralog in the gills of developing shark, bichir, sturgeon, and gar but not in arctic lamprey, suggest that nos expression in this organ likely arose in the last common ancestor of gnathostomes. These results provide a framework for continuing research on nos genes’ roles, highlighting subfunctionalization and reciprocal loss of function that occurred in different lineages during vertebrate genome duplications.

Published
2021

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