126 results on '"Sasaki, Atsuo T"'
Search Results
2. Beyond Warburg: LDHA activates RAC for tumour growth
3. IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma
4. A high dose KRP203 induces cytoplasmic vacuoles associated with altered phosphoinositide segregation and endosome expansion
5. Schlafen 11 predicts response to platinum-based chemotherapy in gastric cancers
6. Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathways
7. TGF-β-dependent reprogramming of amino acid metabolism induces epithelial–mesenchymal transition in non-small cell lung cancers
8. Targeting Energy Metabolism to Overcome Therapeutic Resistance of Glioblastoma and Tumor-associated Edema
9. Integration of Molecular Analysis, Cutting-edge Mouse Genetic Models and Proton Therapy to Improve Outcomes for Glioma Patients
10. Emerging Roles of Wild-type and Mutant IDH1 in Growth, Metabolism and Therapeutics of Glioma
11. Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells
12. Drug discovery targeting GTP metabolism for cancer and infectious diseases using X-ray crystallography and cryo-EM
13. Data from Characterization of KRAS Rearrangements in Metastatic Prostate Cancer
14. Supplementary Methods and Data (posted 7/5/2011) from Characterization of KRAS Rearrangements in Metastatic Prostate Cancer
15. Supplementary Methods, Figures, Tables, and References from Characterization of KRAS Rearrangements in Metastatic Prostate Cancer
16. Functional molecular evolution of a GTP sensing kinase: PI5P4Kβ
17. Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells
18. Homogeneous luminescent quantitation of cellular guanosine and adenosine triphosphates (GTP and ATP) using QT-LucGTP&ATP assay.
19. IMPDH inhibition activates TLR‐VCAM1 pathway and suppresses the development of MLL‐fusion leukemia
20. Epigenetic upregulation of Schlafen11 renders WNT- and SHH-activated medulloblastomas sensitive to cisplatin
21. The GTP responsiveness of PI5P4Kβ evolved from a compromised trade-off between activity and specificity
22. Method for Assaying the Lipid Kinase Phosphatidylinositol-5-phosphate 4-kinase α in Quantitative High-Throughput Screening (qHTS) Bioluminescent Format
23. IMPDH inhibition activates TLR‐VCAM1 pathway and suppresses the development of MLL‐fusion leukemia.
24. SI-MOIRAI: A new method to identify and quantify the metabolic fate of nucleotides
25. Divergent Mechanisms Activating RAS and Small GTPases Through Post-translational Modification
26. Mycophenolate Mofetil Hepatotoxicity Associated With Mitochondrial Abnormality in Liver Transplant Recipients and Mice
27. Reuse of Molecules for Glioblastoma Therapy
28. Metabolic Compartmentalization at the Leading Edge of Metastatic Cancer Cells
29. GTP metabolic reprogramming by IMPDH2: unlocking cancer cells’ fuelling mechanism
30. Activity-specificity trade-off gives PI5P4Kβ a nucleotide preference to function as a GTP-sensing kinase
31. Structure–Activity Relationship Study of Covalent Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors
32. Correction: Identification of lysine methylation in the core GTPase domain by GoMADScan
33. Identification of lysine methylation in the core GTPase domain by GoMADScan
34. Dynamic compartmentalization of purine nucleotide metabolic enzymes at leading edge in highly motile renal cell carcinoma
35. Depletion of phosphatidylinositol 4-phosphate at the Golgi translocates K-Ras to mitochondria
36. In-vitro evaluation of MPA-loaded electrospun coaxial fiber membranes for local treatment of glioblastoma tumor cells
37. R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling
38. Pharmacologic Targeting of S6K1 in PTEN-Deficient Neoplasia
39. Inhibition of Impdh As an Effective Treatment for MLL-Fusion Leukemia
40. Structural reverse genetics study of the PI5P4Kβ-nucleotide complexes reveals the presence of the GTP bioenergetic system in mammalian cells
41. Use of Multiple Cryoprotectants to Improve Diffraction Quality from Protein Crystals
42. Dynamic Role of the GTP Energy Metabolism in Cancers
43. The Lipid Kinase PI5P4Kβ Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
44. Use of Multiple Cryoprotectants to Improve Diffraction Quality from Protein Crystals.
45. Anti-Tumor Potential of IMP Dehydrogenase Inhibitors: A Century-Long Story.
46. Epigenetic upregulation of Schlafen11 renders WNT- and SHH-activated medulloblastomas sensitive to cisplatin.
47. SI-MOIRAI: a new method to identify and quantify the metabolic fate of nucleotides.
48. Integration of Molecular Analysis, Cutting-edge Mouse Genetic Models and Proton Therapy to Improve Outcomes for Glioma Patients
49. Emerging Roles of Wild-type and Mutant IDH1 in Growth, Metabolism and Therapeutics of Glioma
50. Targeting Energy Metabolism to Overcome Therapeutic Resistance of Glioblastoma and Tumor-associated Edema
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