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5. Emulation of the control cohort of a randomized controlled trial in pediatric kidney transplantation with Real-World Data from the CERTAIN Registry

Author

Patry, Christian, Sauer, Lukas D., Sander, Anja, Krupka, Kai, Fichtner, Alexander, Brezinski, Jolanda, and Geissbühler, Yvonne

Subjects
Kidneys -- Transplantation, Children -- Health aspects, Health
Abstract

Background Randomized controlled trials in pediatric kidney transplantation are hampered by low incidence and prevalence of kidney failure in children. Real-World Data from patient registries could facilitate the conduct of clinical trials by substituting a control cohort. However, the emulation of a control cohort by registry data in pediatric kidney transplantation has not been investigated so far. Methods In this multicenter comparative analysis, we emulated the control cohort (n = 54) of an RCT in pediatric kidney transplant patients (CRADLE trial; ClinicalTrials.gov NCT01544491) with data derived from the Cooperative European Paediatric Renal Transplant Initiative (CERTAIN) registry, using the same inclusion and exclusion criteria (CERTAIN cohort, n = 554). Results Most baseline patient and transplant characteristics were well comparable between both cohorts. At year 1 posttransplant, a composite efficacy failure end point comprising biopsy-proven acute rejection, graft loss or death (5.8% ± 3.3% vs. 7.5% ± 1.1%, P = 0.33), and kidney function (72.5 ± 24.9 vs. 77.3 ± 24.2 mL/min/1.73 m.sup.2P = 0.19) did not differ significantly between CRADLE and CERTAIN. Furthermore, the incidence and severity of BPAR (5.6% vs. 7.8%), the degree of proteinuria (20.2 ± 13.9 vs. 30.6 ± 58.4 g/mol, P = 0.15), and the key safety parameters such as occurrence of urinary tract infections (24.1% vs. 15.5%, P = 0.10) were well comparable. Conclusions In conclusion, usage of Real-World Data from patient registries such as CERTAIN to emulate the control cohort of an RCT is feasible and could facilitate the conduct of clinical trials in pediatric kidney transplantation. Graphical abstract, Author(s): Christian Patry [sup.1] , Lukas D. Sauer [sup.2] , Anja Sander [sup.2] , Kai Krupka [sup.1] , Alexander Fichtner [sup.1] , Jolanda Brezinski [sup.2] , Yvonne Geissbühler [sup.3] , [...]

Published
2023
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7. Prophylactic effect of retromuscular mesh placement during loop ileostomy closure on incisional hernia incidence—a multicentre randomised patient- and observer-blind trial (P.E.L.I.O.N trial)

Author

Müller, Sven, Weyhe, Dirk, Herrle, Florian, Horvath, Philipp, Bachmann, Robert, von Ehrlich-Treuenstätt, Viktor, Heger, Patrick, Nasir, Nadir, Klose, Christina, Ritz, Alexander, Sander, Anja, Grohmann, Erich, Dörr-Harim, Colette, and Mihaljevic, André L.

Published
2023
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10. Statistische Tests und Grafiken

Author

Benner, Laura, Kirchner, Marietta, Krisam, Johannes, Kunzmann, Kevin, Sander, Anja, Benner, Laura, Kirchner, Marietta, Krisam, Johannes, Kunzmann, Kevin, and Sander, Anja

Published
2019
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12. Deskriptive Auswertung

Author

Benner, Laura, Kirchner, Marietta, Krisam, Johannes, Kunzmann, Kevin, Sander, Anja, Benner, Laura, Kirchner, Marietta, Krisam, Johannes, Kunzmann, Kevin, and Sander, Anja

Published
2019
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14. What Do Parents Expect from a Genetic Diagnosis of Their Child with Intellectual Disability?

Author

Dikow, Nicola, Moog, Ute, Karch, Stephanie, Sander, Anja, Kilian, Samuel, Blank, Rainer, and Reuner, Gitta

Abstract

Background: Caring for a child with intellectual disability (ID) has been associated with increased social and psychological burdens. Diagnostic and prognostic uncertainty may enhance emotional stress in families. Method: The present authors assessed the motivations, expectations, mental health, physical health and the quality of life of 194 parents whose children with intellectual disability were undergoing a genetic diagnostic workup. Results: Most parents considered a diagnosis highly relevant for their own emotional relief, their child's therapies and education, or family planning. Parental mental health was significantly lower compared with the normative sample, but physical health was not different. The severity of the child's intellectual disability correlated negatively with their parents' mental and physical health, quality of life, and positively with parental anxiety. Conclusion: Healthcare providers should be aware of the disadvantages facing families with intellectually disabled children. Receiving practical, social and psychological support as well as genetic testing might be particularly relevant for families with severely disabled children.

Published
2019
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15. Daily AI-Based Treatment Adaptation under Weekly Offline MR Guidance in Chemoradiotherapy for Cervical Cancer 1: The AIM-C1 Trial

Author

Weykamp, Fabian, primary, Meixner, Eva, additional, Arians, Nathalie, additional, Hoegen-Saßmannshausen, Philipp, additional, Kim, Ji-Young, additional, Tawk, Bouchra, additional, Knoll, Maximilian, additional, Huber, Peter, additional, König, Laila, additional, Sander, Anja, additional, Mokry, Theresa, additional, Meinzer, Clara, additional, Schlemmer, Heinz-Peter, additional, Jäkel, Oliver, additional, Debus, Jürgen, additional, and Hörner-Rieber, Juliane, additional

Published
2024
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16. Phase I trial of donor-derived modified immune cell infusion in kidney transplantation

Author

Morath, Christian, Schmitt, Anita, Kleist, Christian, Daniel, Volker, Opelz, Gerhard, Susal, Caner, Ibrahim, Eman, Kalble, Florian, Speer, Claudius, Nusshag, Christian, da Silva, Luiza Pego, Sommerer, Claudia, Wang, Lei, Ni, Ming, Huckelhoven-Krauss, Angela, Czock, David, Merle, Uta, Mehrabi, Arianeb, Sander, Anja, Hackbusch, Matthes, Eckert, Christoph, Waldherr, Rudiger, Schnitzler, Paul, Muller-Tidow, Carsten, Hoheisel, Jorg D., Mustafa, Shakhawan A., Alhamdani, Mohamed S.S., Bauer, Andrea S., Reiser, Jochen, Zeier, Martin, Schmitt, Michael, Schaier, Matthias, and Terness, Peter

Subjects
Clinical trials, B cells, Kidney transplantation, Medical research, Immunotherapy, Mycophenolate sodium -- Product development, Tissue donation, HLA antigens, Antigens, Surgery, Lymphocytes, Technology, Organ transplantation, Health care industry
Abstract

BACKGROUND. Preclinical experiments have shown that donor blood cells, modified in vitro by an alkylating agent (modified immune cells [MICs]), induced long-term specific immunosuppression against the allogeneic donor. METHODS. In this phase I trial, patients received either 1.5 * [10.sup.6] MICs per kg BW on day -2 (n = 3, group A), or 1.5 * [10.sup.8] MICs per kg BW on day -2 (n = 3, group B) or day -7 (n = 4, group C) before living donor kidney transplantation in addition to posttransplantation immunosuppression. The primary outcome measure was the frequency of adverse events (AEs) until day 30 (study phase) with follow-up out to day 360. RESULTS. MIC infusions were extremely well tolerated. During the study phase, 10 treated patients experienced a total of 69 AEs that were unlikely to be related or not related to MIC infusion. No donor-specific human leukocyte antigen Abs or rejection episodes were noted, even though the patients received up to 1.3 * 1010 donor mononuclear cells before transplantation. Group C patients with low immunosuppression during follow-up showed no in vitro reactivity against stimulatory donor blood cells on day 360, whereas reactivity against third-party cells was still preserved. Frequencies of [CD19.sup.+][CD24.sup.hi][CD38.sup.hi] transitional B lymphocytes (Bregs) increased from a median of 6% before MIC infusion to 20% on day 180, which was 19- and 68-fold higher, respectively, than in 2 independent cohorts of transplanted controls. The majority of Bregs produced the immunosuppressive cytokine IL-10. MIC-treated patients showed the Immune Tolerance Network operational tolerance signature. CONCLUSION. MIC administration was safe and could be a future tool for the targeted induction of tolerogenic Bregs. TRIAL REGISTRATION. EudraCT number: 2014-002086-30; ClinicalTrials.gov identifier: NCT02560220. FUNDING. Federal Ministry for Economic Affairs and Technology, Berlin, Germany, and TolerogenixX GmbH, Heidelberg, Germany., Introduction Long-term renal allograft survival is limited for 2 reasons: first, conventional immunosuppression is not capable of preventing chronic rejection, which is responsible for more than half of graft losses; [...]

Published
2020
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17. Early intervention, treatment and rehabilitation of employees with common mental disorders by using psychotherapeutic consultation at work: study protocol of a randomised controlled multicentre trial (friaa project)

Author

Weber, Jeannette, Angerer, Peter, Brenner, Lorena, Brezinski, Jolanda, Chrysanthou, Sophia, Erim, Yesim, Feißt, Manuel, Hansmann, Marieke, Hondong, Sinja, Kessemeier, Franziska Maria, Kilian, Reinhold, Klose, Christina, Köllner, Volker, Kohl, Fiona, Krisam, Regina, Kröger, Christoph, Sander, Anja, Schröder, Ute Beate, Stegmann, Ralf, Wegewitz, Uta, Gündel, Harald, Rothermund, Eva, and Herrmann, Kristin

Published
2021
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19. A strategic neurological research agenda for Europe: Towards clinically relevant and patient‐centred neurological research priorities

Author

Boon, Paul, primary, Lescrauwaet, Emma, additional, Aleksovska, Katina, additional, Konti, Maria, additional, Berger, Thomas, additional, Leonardi, Matilde, additional, Marson, Tony, additional, Kallweit, Ulf, additional, Moro, Elena, additional, Toscano, Antonio, additional, Rektorova, Irena, additional, Crean, Michael, additional, Sander, Anja, additional, Joyce, Robert, additional, and Bassetti, Claudio, additional

Published
2023
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20. Einleitung

Author

Benner, Laura, Kirchner, Marietta, Krisam, Johannes, Kunzmann, Kevin, Sander, Anja, Benner, Laura, Kirchner, Marietta, Krisam, Johannes, Kunzmann, Kevin, and Sander, Anja

Published
2019
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21. Risk Factors for Early Dialysis Dependency in Autosomal Recessive Polycystic Kidney Disease

Author

Ranguelov, Nadejda, Godefroid, Nathalie, Collard, Laure, Lombet, Jacques, Maquet, Julie, Schalk, Gesa, Querfeld, Uwe, Beck, Bodo B., Benzing, Thomas, Buettner, Reinhard, Grundmann, Franziska, Kurschat, Christine, Benz, Kerstin, Tzschoppe, Anja, Buchholz, Björn, Buescher, Rainer, Häffner, Karsten, Pohl, Martin, Gross, Oliver, Krügel, Jenny, Stock, Johanna, Patzer, Ludwig, Oh, Jun, Bernhardt, Wanja, Doyon, Anke, Vinke, Tobias, Sander, Anja, Henn, Michael, Derichs, Ute, Beetz, Rolf, Jeck, Nikola, Lange-Sperandio, Bärbel, Ponsel, Sabine, Kusser, Franziska, Uetz, Barbara, Benz, Marcus, Schmidt, Silke, Huppertz-Kessler, Christina, Kranz, Birgitta, Titieni, Andrea, Wurm, Donald, Leichter, Heinz E., Bald, Martin, Billing, Heiko, Nabhan, Marwa M., Lara, Luis Enrique, Papachristou, Fotios, Emma, Francesco, Cerkauskiene, Rimante, Azukaitis, Karolis, Wasilewska, Anna, Balasz-Chmielewska, Irena, Miklaszewska, Monika, Tkaczyk, Marcin, Sikora, Przemyslaw, Zaniew, Marcin, Niemirska, Ania, Antoniewicz, Jolanta, Lesiak, Justyna, Afonso, Alberto Caldas, Teixeira, Ana, Milosevski-Lomic, Gordana, Paripović, Dusan, Peco-Antic, Amira, Papizh, Svetlana, Bayazit, Aysun Karabay, Anarat, Ali, Soylu, Alper, Kavukcu, Salih, Candan, Cengiz, Caliskan, Salim, Canpolat, Nur, Emre, Sevinc, Alpay, Harika, Akinci, Nurver, Conkar, Secil, Poyrazoglu, Hakan M., Dusunsel, Ruhan, Burgmaier, Kathrin, Kunzmann, Kevin, Ariceta, Gema, Bergmann, Carsten, Buescher, Anja Katrin, Burgmaier, Mathias, Dursun, Ismail, Duzova, Ali, Eid, Loai, Erger, Florian, Feldkoetter, Markus, Galiano, Matthias, Geßner, Michaela, Goebel, Heike, Gokce, Ibrahim, Haffner, Dieter, Hooman, Nakysa, Hoppe, Bernd, Jankauskiene, Augustina, Klaus, Guenter, König, Jens, Litwin, Mieczyslaw, Massella, Laura, Mekahli, Djalila, Melek, Engin, Mir, Sevgi, Pape, Lars, Prikhodina, Larisa, Ranchin, Bruno, Schild, Raphael, Seeman, Tomas, Sever, Lale, Shroff, Rukshana, Soliman, Neveen A., Stabouli, Stella, Stanczyk, Malgorzata, Tabel, Yilmaz, Taranta-Janusz, Katarzyna, Testa, Sara, Thumfart, Julia, Topaloglu, Rezan, Weber, Lutz Thorsten, Wicher, Dorota, Wühl, Elke, Wygoda, Simone, Yilmaz, Alev, Zachwieja, Katarzyna, Zagozdzon, Ilona, Zerres, Klaus, Dötsch, Jörg, Schaefer, Franz, and Liebau, Max Christoph

Published
2018
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24. A strategic neurological research agenda for Europe: Towards clinically relevant and patient‐centred neurological research priorities.

Author

Boon, Paul, Lescrauwaet, Emma, Aleksovska, Katina, Konti, Maria, Berger, Thomas, Leonardi, Matilde, Marson, Tony, Kallweit, Ulf, Moro, Elena, Toscano, Antonio, Rektorova, Irena, Crean, Michael, Sander, Anja, Joyce, Robert, and Bassetti, Claudio

Subjects
NEUROLOGICAL research, LITERATURE reviews, EVIDENCE gaps, BRAIN research, GLOBAL burden of disease
Abstract

Background and purpose: Neurological disorders constitute a significant portion of the global disease burden, affecting >30% of the world's population. This prevalence poses a substantial threat to global health in the foreseeable future. A lack of awareness regarding this high burden of neurological diseases has led to their underrecognition, underappreciation, and insufficient funding. Establishing a strategic and comprehensive research agenda for brain‐related studies is a crucial step towards aligning research objectives among all pertinent stakeholders and fostering greater societal awareness. Methods: A scoping literature review was undertaken by a working group from the European Academy of Neurology (EAN) to identify any existing research agendas relevant to neurology. Additionally, a specialized survey was conducted among all EAN scientific panels, including neurologists and patients, inquiring about their perspectives on the current research priorities and gaps in neurology. Results: The review revealed the absence of a unified, overarching brain research agenda. Existing research agendas predominantly focus on specialized topics within neurology, resulting in an imbalance in the number of agendas across subspecialties. The survey indicated a prioritization of neurological disorders and research gaps. Conclusions: Building upon the findings from the review and survey, key components for a strategic and comprehensive neurological research agenda in Europe were delineated. This research agenda serves as a valuable prioritization tool for neuroscientific researchers, as well as for clinicians, donors, and funding agencies in the field of neurology. It offers essential guidance for creating a roadmap for research and clinical advancement, ultimately leading to heightened awareness and reduced burden of neurological disorders. [ABSTRACT FROM AUTHOR]

Published
2024
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29. Deskriptive Auswertung

Author

Benner, Laura, primary, Kirchner, Marietta, additional, Krisam, Johannes, additional, Kunzmann, Kevin, additional, and Sander, Anja, additional

Published
2018
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30. Einleitung

Author

Benner, Laura, primary, Kirchner, Marietta, additional, Krisam, Johannes, additional, Kunzmann, Kevin, additional, and Sander, Anja, additional

Published
2018
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32. Global Variation of Nutritional Status in Children Undergoing Chronic Peritoneal Dialysis: A Longitudinal Study of the International Pediatric Peritoneal Dialysis Network

Author

Schaefer, Franz, Benner, Laura, Borzych-Dużałka, Dagmara, Zaritsky, Joshua, Xu, Hong, Rees, Lesley, Antonio, Zenaida L., Serdaroglu, Erkin, Hooman, Nakysa, Patel, Hiren, Sever, Lale, Vondrak, Karel, Flynn, Joseph, Rébori, Anabella, Wong, William, Hölttä, Tuula, Yildirim, Zeynep Yuruk, Ranchin, Bruno, Grenda, Ryszard, Testa, Sara, Drożdz, Dorota, Szabo, Attila J., Eid, Loai, Basu, Biswanath, Vitkevic, Renata, Wong, Cynthia, Pottoore, Stephen J., Müller, Dominik, Dusunsel, Ruhan, Celedon, Claudia Gonzalez, Fila, Marc, Sartz, Lisa, Sander, Anja, Warady, Bradley A., and International Pediatric Peritoneal Dialysis Network (IPPN) Registry

Published
2019
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33. Additional file 2 of Prophylactic effect of retromuscular mesh placement during loop ileostomy closure on incisional hernia incidence—a multicentre randomised patient- and observer-blind trial (P.E.L.I.O.N trial)

Author

Müller, Sven, Weyhe, Dirk, Herrle, Florian, Horvath, Philipp, Bachmann, Robert, von Ehrlich-Treuenstätt, Viktor, Heger, Patrick, Nasir, Nadir, Klose, Christina, Ritz, Alexander, Sander, Anja, Grohmann, Erich, Dörr-Harim, Colette, and Mihaljevic, André L.

Abstract

Additional file 2. Study specific instruments of the P.E.L.I.O.N. trial.

Published
2023
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34. Additional file 1 of Prophylactic effect of retromuscular mesh placement during loop ileostomy closure on incisional hernia incidence—a multicentre randomised patient- and observer-blind trial (P.E.L.I.O.N trial)

Author

Müller, Sven, Weyhe, Dirk, Herrle, Florian, Horvath, Philipp, Bachmann, Robert, von Ehrlich-Treuenstätt, Viktor, Heger, Patrick, Nasir, Nadir, Klose, Christina, Ritz, Alexander, Sander, Anja, Grohmann, Erich, Dörr-Harim, Colette, and Mihaljevic, André L.

Abstract

Additional file 1. List of study sites.

Published
2023
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35. Prophylactic Effect of retromuscular mesh during Loop Ileostomy closure On incisional herNia incidence – a multicentre randomized patient- and observer-blind trial (P.E.L.I.O.N Trial).

Author

Müller, Sven, primary, Weyhe, Dirk, additional, Herrle, Florian, additional, Horvath, Philipp, additional, Bachmann, Robert, additional, von Ehrlich-Treuenstätt, Viktor, additional, Heger, Patrick, additional, Nasir, Nadir, additional, Klose, Christina, additional, Ritz, Alexander, additional, Sander, Anja, additional, Grohmann, Erich, additional, Dörr-Harim, Colette, additional, and Mihaljevic, Andre L., additional

Published
2022
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36. Education Research: Impact of Burnout on Neurology Residents and Research Fellows in Europe

Author

Di Liberto, Giovanni, primary, Baldizzi, Giuseppina, additional, Carvalho, Vanessa, additional, Cuffaro, Luca, additional, Sauerbier, Anna, additional, Klingelhoefer, Lisa, additional, Vashchenko, Nina, additional, Pavlakova, Lucia, additional, Sander, Anja, additional, de Visser, Marianne, additional, Boon, Paul A.J.M., additional, Moro, Elena, additional, and Bassetti, Claudio, additional

Published
2022
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37. Perioperative prothrombin complex concentrate and fibrinogen administration are associated with thrombotic complications after liver transplant

Author

Dehne, Sarah, primary, Riede, Carlo, additional, Klotz, Rosa, additional, Sander, Anja, additional, Feisst, Manuel, additional, Merle, Uta, additional, Mieth, Markus, additional, Golriz, Mohammad, additional, Mehrabi, Arianeb, additional, Büchler, Markus W., additional, Weigand, Markus A., additional, and Larmann, Jan, additional

Published
2022
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39. Individualised immunosuppression with intravenously administered donor-derived modified immune cells compared with standard of care in living donor kidney transplantation (TOL-2 Study): protocol for a multicentre, open-label, phase II, randomised controlled trial

Author

Morath, Christian, primary, Schmitt, Anita, additional, Schmitt, Michael, additional, Wang, Lei, additional, Kleist, Christian, additional, Opelz, Gerhard, additional, Süsal, Caner, additional, Tran, T. Hien, additional, Scherer, Sabine, additional, Schwenger, Vedat, additional, Kemmner, Stephan, additional, Fischereder, Michael, additional, Stangl, Manfred, additional, Hauser, Ingeborg A., additional, Sommerer, Claudia, additional, Nusshag, Christian, additional, Kälble, Florian, additional, Speer, Claudius, additional, Benning, Louise, additional, Bischofs, Christian, additional, Sauer, Sandra, additional, Schubert, Maria-Luisa, additional, Kunz, Alexander, additional, Hückelhoven-Krauss, Angela, additional, Neuber, Brigitte, additional, Mehrabi, Arianeb, additional, Schwab, Constantin, additional, Waldherr, Rüdiger, additional, Sander, Anja, additional, Büsch, Christopher, additional, Czock, David, additional, Böhmig, Georg A, additional, Reiser, Jochen, additional, Roers, Axel, additional, Müller-Tidow, Carsten, additional, Terness, Peter, additional, Zeier, Martin, additional, Daniel, Volker, additional, and Schaier, Matthias, additional

Published
2022
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40. Emulation of the control cohort of a randomized controlled trial in pediatric kidney transplantation with Real-World Data from the CERTAIN Registry

Author

Patry, Christian, primary, Sauer, Lukas D., additional, Sander, Anja, additional, Krupka, Kai, additional, Fichtner, Alexander, additional, Brezinski, Jolanda, additional, Geissbühler, Yvonne, additional, Aubrun, Elodie, additional, Grinienko, Anna, additional, Strologo, Luca Dello, additional, Haffner, Dieter, additional, Oh, Jun, additional, Grenda, Ryszard, additional, Pape, Lars, additional, Topaloğlu, Rezan, additional, Weber, Lutz T., additional, Bouts, Antonia, additional, Kim, Jon Jin, additional, Prytula, Agnieszka, additional, König, Jens, additional, Shenoy, Mohan, additional, Höcker, Britta, additional, and Tönshoff, Burkhard, additional

Published
2022
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41. Early Effects of Renal Replacement Therapy on Cardiovascular Comorbidity in Children With End-Stage Kidney Disease: Findings From the 4C-T Study

Author

Schmidt, Bernhard M.W., Sugianto, Rizky Indrameikha, Thurn, Daniela, Azukaitis, Karolis, Bayazit, Aysun K., Canpolat, Nur, Eroglu, Ayse Guler, Caliskan, Salim, Doyon, Anke, Duzova, Ali, Karagoz, Tevfik, Anarat, Ali, Deveci, Murat, Mir, Sevgi, Ranchin, Bruno, Shroff, Rukshana, Baskin, Esra, Litwin, Mieczyslaw, Özcakar, Z. Birsin, Büscher, Rainer, Soylemezoglu, Oguz, Dusek, Jiri, Kemper, Markus J., Matteucci, Maria C., Habbig, Sandra, Laube, Guido, Wühl, Elke, Querfeld, Uwe, Sander, Anja, Schaefer, Franz, and Melk, Anette

Published
2018
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42. Beschäftigte am Arbeitsplatz Krankenhaus stärken: Das BMBF-Verbundprojekt SEEGEN

Author

Hander, Nicole, Baxendale, Maximilian, Gantner, Melanie, Mulfinger, Nadine, Jarczok, Marc, Junne, Florian, Stuber, Felicitas, Rieger, Monika, Radionova, Natalia, Nikendei, Christoph, Maatouk, Imad, Helaß, Madeleine, Greinacher, Anja, Schweitzer-Rothers, Jochen, Küllenberg, Janna Katharina, Rothermund, Eva, Klein, Thomas, Ziegenhain, Ute, Gulde, Manuela, Ruhle, Sascha Alexander, Süß, Stefan, Gesang, Elena, Müller, Andreas, Genrich, Melanie, Angerer, Peter, Worringer, Britta, Puschner, Bernd, Stiawa, Maja, Peters, Martin, Sander, Anja, and Gündel, Harald

Subjects
ddc: 610, Medicine and health
Abstract

Hintergrund und Stand (inter)nationaler Forschung: Gerade im Bereich der Krankenhäuser, die in den letzten Jahrzenten einen enormen Wandel bei den Arbeitsbedingungen z.B. durch Kostendämpfungsmaßnahmen vollzogen haben, fehlt ein systematisiertes betriebliches Gesundheitsmanagement. Wie [zum vollständigen Text gelangen Sie über die oben angegebene URL]

Published
2022

44. Intraoperative visualisation of pancreatic leakage (ViP): study protocol for an IDEAL Stage I Post Market Clinical Study

Author

Pausch, Thomas M, primary, Holze, Magdalena, additional, Gesslein, Bodil, additional, Rossion, Inga, additional, von Eisenhart Rothe, Franziska, additional, Wagner, Martin, additional, Sander, Anja, additional, Tenckhoff, Solveig, additional, Bartel, Marc, additional, Larmann, Jan, additional, Probst, Pascal, additional, Pianka, Frank, additional, Hackert, Thilo, additional, and Klotz, Rosa, additional

Published
2022
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46. MO1041: C.E.R.A. (Continuous Erythropoietin Receptor Activator—Methoxy Polyethylene Glycol Epoetin Beta) In Paediatric Dialysis Patients with Anaemia of Chronic Kidney Disease: Real-World Evidence from the IPDN and IPHN Registries

Author

Schaefer, Franz, primary, Benner, Laura, additional, Sander, Anja, additional, Rutten-Jacobs, Loes, additional, Hui Kim, Yap, additional, Vondrak, Karel, additional, Coccia, Paula A, additional, Cano, Francisco, additional, Meyer Reigner, Sylvie, additional, and Studer, Milena, additional

Published
2022
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48. Neozytolyse: Ein Konzept aus der Raumfahrt konnte in den Schweizer Alpen nicht bestätigt werden

Author

Kaestner, Lars, additional, Klein, Marie, additional, Bogdanova, Anna Y., additional, Minetti, Giampaolo, additional, Rudloff, Silvia, additional, Lundby, Carsten, additional, Makhro, Asya, additional, Seiler, Elena, additional, van Cromvoirt, Ankie, additional, Fenk, Simone, additional, Simionato, Greta, additional, Hertz, Laura, additional, Recktenwald, Steffen, additional, Schäfer, Larissa, additional, Haider, Thomas, additional, Fried, Sebastian, additional, Borsch, Christian, additional, Marti, Hugo H., additional, Sander, Anja, additional, and Mairbäurl, Heimo, additional

Published
2021
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49. Additional file 1 of Early intervention, treatment and rehabilitation of employees with common mental disorders by using psychotherapeutic consultation at work: study protocol of a randomised controlled multicentre trial (friaa project)

Author

Weber, Jeannette, Angerer, Peter, Brenner, Lorena, Brezinski, Jolanda, Chrysanthou, Sophia, Erim, Yesim, Feißt, Manuel, Hansmann, Marieke, Hondong, Sinja, Kessemeier, Franziska Maria, Kilian, Reinhold, Klose, Christina, Köllner, Volker, Kohl, Fiona, Krisam, Regina, Kröger, Christoph, Sander, Anja, Schröder, Ute Beate, Stegmann, Ralf, Wegewitz, Uta, Gündel, Harald, Rothermund, Eva, and Herrmann, Kristin

Abstract

Additional file 1. Study questionnaire for sociodemographic variables and days of sickness absence.

Published
2021
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50. Evaluation of the 2020 EAN Virtual Congress: transition from a face-to-face to a virtual meeting

Author

Stamelou, Maria, Struhal, Walter, Ten Cate, Olle, Matczak, Magdalena, Çalışkan, S Ayhan, Soffietti, Riccardo, Marson, Anthony, Zis, Panagiotis, di Lorenzo, Francesco, Sander, Anja, Deuschl, Günther, de Visser, Marianne, and Bassetti, Claudio L.A.

Subjects
evaluation, international congress, quality, transition, virtual congress, 610 Medicine & health
Abstract

BACKGROUND Due to the COVID-19 pandemic, scientific congresses are increasingly being organised as virtual congresses. In May 2020, the European Academy of Neurology (EAN) held a VC, free-of-charge. In the absence of systematic studies on this topic, the aim of this study is to evaluate the attendance and perceived quality of the 2020 EAN virtual congress (VC) compared to the 2019 EAN face-to-face congress (FFC). METHODS Analysis of demographic data of participants obtained from the online registration collected. Comparison of the two congresses based on a survey with questions on the perception of speakers' performance, quality of networking, and other aspects. RESULTS Of 43,596 registered participants, 20,694 active participants attended the VC. Compared to 2019, the number of participants tripled (6916 in 2019) and the cumulated number of participants attending the sessions was five times higher (169,334 in 2020 vs 33,024 in 2019). Out of active participants 55% were from outside Europe, 42% were board-certified neurologists (FFC: 80%), and 21% were students (FFC: 0.6%). The content of the congress was evaluated as 'above expectation' by 56% of the attendees (FFC: 41%). Out of the respondents who had been exposed to earlier EAN congresses 73% preferred the FFC congress compared to the VC (17%). CONCLUSION The VC fulfilled the main mission of organizing high quality EAN congresses despite the restrictions of the impersonal format. The geographical distribution of the participants prove the expected higher inclusivity of a VC. The large participation of students and neurologists in training opens new educational potentials for the EAN.

Published
2021
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