442 results on '"Roeder, Robert G"'
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2. TAF2, within the TFIID complex, regulates the expression of a subset of protein-coding genes
3. Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment
4. Regulation of the RNA polymerase II pre-initiation complex by its associated coactivators
5. MLL-AF9 regulates transcriptional initiation in mixed lineage leukemic cells
6. An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II
7. MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia
8. Structural basis for evolutionarily conserved interactions between TFIIS and Paf1C
9. Cooperation between IRTKS and deubiquitinase OTUD4 enhances the SETDB1-mediated H3K9 trimethylation that promotes tumor metastasis via suppressing E-cadherin expression
10. Two target gene activation pathways for orphan ERR nuclear receptors
11. Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin
12. Functional partitioning of transcriptional regulators by patterned charge blocks
13. The Histone Deacetylase SIRT6 Restrains Transcription Elongation via Promoter-Proximal Pausing.
14. DOT1L complex regulates transcriptional initiation in human erythroleukemic cells
15. Mediator subunit MED1 is required for E2A-PBX1–mediated oncogenic transcription and leukemic cell growth
16. Histone H3Q5 serotonylation stabilizes H3K4 methylation and potentiates its readout
17. EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis
18. Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1
19. Structural basis of human SNAPc recognizing proximal sequence element of snRNA promoter
20. Functions of paralogous RNA polymerase III subunits POLR3G and POLR3GL in mouse development
21. OCT2 pre-positioning facilitates cell fate transition and chromatin architecture changes in humoral immunity
22. CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas
23. Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage
24. A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms
25. E2A-PBX1 functions as a coactivator for RUNX1 in acute lymphoblastic leukemia
26. Gene-Specific Control of tRNA Expression by RNA Polymerase II
27. MED1 IDR acetylation reorganizes the transcription preinitiation complex, rewires 3D chromatin interactions and reprograms gene expression
28. Chromatin Kinases Act on Transcription Factors and Histone Tails in Regulation of Inducible Transcription
29. AFF1 acetylation by p300 temporally inhibits transcription during genotoxic stress response
30. Different roles of E proteins in t(8;21) leukemia : E2-2 compromises the function of AETFC and negatively regulates leukemogenesis
31. Self-Enforcing Feedback Activation between BCL6 and Pre-B Cell Receptor Signaling Defines a Distinct Subtype of Acute Lymphoblastic Leukemia
32. Transcription recycling assays identify PAF1 as a driver for RNA Pol II recycling
33. MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition
34. Gene-Specific H1 Eviction through a Transcriptional Activator→p300→NAP1→H1 Pathway
35. Multivalent Role of Human TFIID in Recruiting Elongation Components at the Promoter-Proximal Region for Transcriptional Control
36. Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment.
37. Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology
38. Coactivator condensation at super-enhancers links phase separation and gene control
39. A noncanonical PPARγ/RXRα-binding sequence regulates leptin expression in response to changes in adipose tissue mass
40. p300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis
41. Metabolic regulation of gene expression by histone lactylation
42. 50+ years of eukaryotic transcription: an expanding universe of factors and mechanisms
43. Destabilization of AETFC through C/EBPα-mediated repression of LYL1 contributes to t(8;21) leukemic cell differentiation
44. Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3
45. SETD1A function in leukemia is mediated through interaction with mitotic regulators BuGZ/BUB3
46. A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription
47. Control of Secreted Protein Gene Expression and the Mammalian Secretome by the Metabolic Regulator PGC-1α
48. Transcription of Class III Genes: Formation of Preinitiation Complexes
49. Proteomic profiling identifies key coactivators utilized by mutant ERα proteins as potential new therapeutic targets
50. SET1 and p300 Act Synergistically, through Coupled Histone Modifications, in Transcriptional Activation by p53
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