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411 results on '"Reichlin, T."'

1. Impact of early recurrences on late recurrences after pulmonary vein isolation with pulsed field ablation. A subanalysis from the EU-PORIA multicenter international registry

Author

Bordignon, S, primary, Chun, K R J, additional, Neven, K, additional, Mulder, B A, additional, Kueffer, T, additional, Reichlin, T, additional, Hansen, J, additional, Blaauw, Y, additional, Ouss, A, additional, Reinsch, N, additional, Albrecht, E, additional, Boveda, S, additional, and Schmidt, B, additional

Published
2024
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3. Comparison of pulsed field ablation and thermal ablation for repeat procedures after failed prior thermal ablation for atrial fibrillation

Author

Baskaralingam, A, primary, Kueffer, T, additional, Maurhofer, J, additional, Madaffari, A, additional, Thalmann, G, additional, Kozhuharov, N A, additional, Galuszka, O, additional, Rehman, S, additional, Servatius, H, additional, Haeberlin, A, additional, Noti, F, additional, Tanner, H, additional, Roten, L, additional, and Reichlin, T, additional

Published
2024
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4. Impact of the timing of early recurrences during the blanking period in patients after cryoballoon ablation: insights from the COMPARE CRYO study using continuous rhythm monitoring

Author

Rehman, S, primary, Kueffer, T, additional, Knecht, S, additional, Madaffari, A, additional, Badertscher, P, additional, Maurhofer, J, additional, Krisai, P, additional, Thalmann, G, additional, Heg, D, additional, Servatius, H, additional, Tanner, H, additional, Kuhne, M, additional, Roten, L, additional, Sticherling, C, additional, and Reichlin, T, additional

Published
2024
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5. Durability of pulmonary vein isolation with pulsed field ablation compared to radiofrequency ablation in patients with persistent atrial fibrillation: results from a prospective remapping study

Author

Galuszka, O, primary, Baldinger, S, additional, Kueffer, T, additional, Servatius, H, additional, Madaffari, A, additional, Kozhuharov, N, additional, Thalmann, G, additional, Herrera Siklody, C, additional, Maurhofer, J, additional, Haeberlin, A, additional, Noti, F, additional, Tanner, H, additional, Reichlin, T, additional, and Roten, L, additional

Published
2024
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6. Procedural and outcome impact of body mass index on pulsed field ablation of atrial fibrillation: insights from the EU-PORIA Registry

Author

Telesca, A, primary, Bordignon, S, additional, Neven, K, additional, Reichlin, T, additional, Blaauw, Y, additional, Hansen, J, additional, Boveda, S, additional, Ouss, A, additional, Mulder, B A, additional, Ruwald, M H, additional, Reinsch, N, additional, Kueffer, T, additional, Albrecht, E M, additional, Chun, J K R, additional, and Schmidt, B, additional

Published
2024
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7. Percutaneous left atrial appendage occlusion can impair pulmonary vein isolation with pulse field ablation

Author

Molitor, N, primary, Berger, F, additional, Breitenstein, A, additional, Chen, S, additional, Chun, J, additional, Galuszka, M, additional, Reichlin, T, additional, Roten, L, additional, Kueffer, T, additional, Lemoine, M, additional, Ouyang, F, additional, Wolber, T, additional, Brunckhorst, C, additional, Duru, F, additional, and Saguner, A, additional

Published
2024
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8. Characterization of ventricular tachycardia ablation in end-stage heart failure patients with left ventricular assist device (CHANNELED-Registry)

Author

Van Den Bruck, J, primary, Khalaph, M, additional, Sommer, P, additional, Duncker, D, additional, Estner, H, additional, Hohendanner, F, additional, Parwani, A, additional, Eckardt, L, additional, Doldi, F, additional, Lugenbiel, P, additional, Metzner, A, additional, Servatius, H, additional, Reichlin, T, additional, Steven, D, additional, and Lueker, J, additional

Published
2024
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9. Scar tissue characterization to predict arrhythmia recurrence in patients undergoing ventricular tachycardia ablation: cardiac computed tomography compared with cardiac magnetic resonance

Author

Galuszka, O, primary, Baldinger, S, additional, Kueffer, T, additional, Madaffari, A, additional, Servatius, H, additional, Kozhuharov, N, additional, Thalmann, G, additional, Boscolo Berto, M, additional, Graeni, C, additional, Maurhofer, J, additional, Haeberlin, A, additional, Noti, F, additional, Tanner, H, additional, Roten, L, additional, and Reichlin, T, additional

Published
2024
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11. 2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation

Author

Tzeis, S, Gerstenfeld, EP, Kalman, J, Saad, EB, Shamloo, AS, Andrade, JG, Barbhaiya, CR, Baykaner, T, Boveda, S, Calkins, H, Chan, N-Y, Chen, M, Chen, S-A, Dagres, N, Damiano, RJ, De Potter, T, Deisenhofer, I, Derval, N, Di Biase, L, Duytschaever, M, Dyrda, K, Hindricks, G, Hocini, M, Kim, Y-H, la Meir, M, Merino, JL, Michaud, GF, Natale, A, Nault, I, Nava, S, Nitta, T, O'Neill, M, Pak, H-N, Piccini, JP, Puererfellner, H, Reichlin, T, Saenz, LC, Sanders, P, Schilling, R, Schmidt, B, Supple, GE, Thomas, KL, Tondo, C, Verma, A, Wan, EY, Tzeis, S, Gerstenfeld, EP, Kalman, J, Saad, EB, Shamloo, AS, Andrade, JG, Barbhaiya, CR, Baykaner, T, Boveda, S, Calkins, H, Chan, N-Y, Chen, M, Chen, S-A, Dagres, N, Damiano, RJ, De Potter, T, Deisenhofer, I, Derval, N, Di Biase, L, Duytschaever, M, Dyrda, K, Hindricks, G, Hocini, M, Kim, Y-H, la Meir, M, Merino, JL, Michaud, GF, Natale, A, Nault, I, Nava, S, Nitta, T, O'Neill, M, Pak, H-N, Piccini, JP, Puererfellner, H, Reichlin, T, Saenz, LC, Sanders, P, Schilling, R, Schmidt, B, Supple, GE, Thomas, KL, Tondo, C, Verma, A, and Wan, EY

Abstract

In the last three decades, ablation of atrial fibrillation (AF) has become an evidence-based safe and efficacious treatment for managing the most common cardiac arrhythmia. In 2007, the first joint expert consensus document was issued, guiding healthcare professionals involved in catheter or surgical AF ablation. Mounting research evidence and technological advances have resulted in a rapidly changing landscape in the field of catheter and surgical AF ablation, thus stressing the need for regularly updated versions of this partnership which were issued in 2012 and 2017. Seven years after the last consensus, an updated document was considered necessary to define a contemporary framework for selection and management of patients considered for or undergoing catheter or surgical AF ablation. This consensus is a joint effort from collaborating cardiac electrophysiology societies, namely the European Heart Rhythm Association, the Heart Rhythm Society, the Asia Pacific Heart Rhythm Society, and the Latin American Heart Rhythm Society .

Published
2024

12. Circadian rhythm of cardiac troponin I and its clinical impact on the diagnostic accuracy for acute myocardial infarction

Author

Wildi, K., Singeisen, H., Twerenbold, R., Badertscher, P., Wussler, D., Klinkenberg, L.J.J., Meex, S.J.R., Nestelberger, T., Boeddinghaus, J., Miró, Ò., Martin-Sanchez, F.J., Morawiec, B., Muzyk, P., Parenica, J., Keller, D.I., Geigy, N., Potlukova, E., Sabti, Z., Kozhuharov, N., Puelacher, C., du Fay de Lavallaz, J., Rubini Gimenez, M., Shrestha, S., Marzano, G., Rentsch, K., Osswald, S., Reichlin, T., and Mueller, C.

Published
2018
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13. Association of red cell omega-3 fatty acids, particularly EPA, with cognitive performance in atrial fibrillation

Author

Lee, P, primary, Bosshard, L, additional, Aeschbacher, S, additional, Springer, A, additional, Saeedi, S, additional, Allemann, M, additional, Bonati, L, additional, Kuhne, M, additional, Reichlin, T, additional, Moschovitis, G, additional, Muller, A, additional, Rodondi, N, additional, Conen, D, additional, Osswald, S, additional, and Beer, J H, additional

Published
2023
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15. The diagnostic accuracy of experienced physicians to clinically discriminate type 1 myocardial infarction from type 2 myocardial infarction or myocardial injury

Author

Bossard, M, primary, Nestelberger, T, additional, Kaiser, C, additional, Gschwend, M, additional, Madanchi, M, additional, Reichlin, T, additional, Toggweiler, S, additional, Majcen, I, additional, Kobza, R, additional, Osswald, S, additional, Cuculi, F, additional, and Mueller, C, additional

Published
2023
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16. Biomarkers for the prediction of cognitive decline in atrial fibrillation patients

Author

Krisai, P, primary, Eberl, M, additional, Coslovsky, M, additional, Rodondi, N, additional, Chocano-Bedoya, P, additional, Kobza, R, additional, Moschovitis, G, additional, Rigamonti, E, additional, Beer, J H, additional, Mueller, A, additional, Reichlin, T, additional, Conen, D, additional, Osswald, S, additional, Bonati, L, additional, and Kuehne, M, additional

Published
2023
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17. STereotactic Arrhythmia Radioablation (STAR): the Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary consortium (STOPSTORM.eu) and review of current patterns of STAR practice in Europe

Author

Grehn, M., Mandija, S., Miszczyk, M., Krug, D., Tomasik, B., Stickney, K. E., Alcantara, P., Alongi, F., Anselmino, M., Aranda, R. S., Balgobind, B. V., Boda-Heggemann, J., Boldt, L.-H., Bottoni, N., Cvek, J., Elicin, O., Ferrari, G. M., Hassink, R. J., Hazelaar, C., Hindricks, G., Hurkmans, C., Iotti, C., Jadczyk, T., Jiravsky, O., Jumeau, R., Kristiansen, S. B., Levis, M., López, M. A., Martí-Almor, J., Mehrhof, F., Møller, D. S., Molon, G., Ouss, A., Peichl, P., Plasek, J., Postema, P. G., Quesada, A., Reichlin, T., Rordorf, R., Rudic, B., Saguner, A. M., Ter, B., Rachel, M. A., Torrecilla, J. L., (0000-0001-9550-9050) Troost, E. G. C., Vitolo, V., Andratschke, N., Zeppenfeld, K., Blamek, S., Fast, M., Panfilis, L., Blanck, O., Pruvot, E., Verhoeff, J. J. C., Grehn, M., Mandija, S., Miszczyk, M., Krug, D., Tomasik, B., Stickney, K. E., Alcantara, P., Alongi, F., Anselmino, M., Aranda, R. S., Balgobind, B. V., Boda-Heggemann, J., Boldt, L.-H., Bottoni, N., Cvek, J., Elicin, O., Ferrari, G. M., Hassink, R. J., Hazelaar, C., Hindricks, G., Hurkmans, C., Iotti, C., Jadczyk, T., Jiravsky, O., Jumeau, R., Kristiansen, S. B., Levis, M., López, M. A., Martí-Almor, J., Mehrhof, F., Møller, D. S., Molon, G., Ouss, A., Peichl, P., Plasek, J., Postema, P. G., Quesada, A., Reichlin, T., Rordorf, R., Rudic, B., Saguner, A. M., Ter, B., Rachel, M. A., Torrecilla, J. L., (0000-0001-9550-9050) Troost, E. G. C., Vitolo, V., Andratschke, N., Zeppenfeld, K., Blamek, S., Fast, M., Panfilis, L., Blanck, O., Pruvot, E., and Verhoeff, J. J. C.

Abstract

The EU Horizon 2020 Framework-funded Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary (STOPSTORM) consortium has been established as a large research network for investigating STereotactic Arrhythmia Radioablation (STAR) for ventricular tachycardia (VT). The aim is to provide a pooled treatment database to evaluate patterns of practice and outcomes of STAR and finally to harmonize STAR within Europe. The consortium comprises 31 clinical and research institutions. The project is divided into nine work packages (WPs): (i) observational cohort; (ii) standardization and harmonization of target delineation; (iii) harmonized prospective cohort; (iv) quality assurance (QA); (v) analysis and evaluation; (vi, ix) ethics and regulations; and (vii, viii) project coordination and dissemination. To provide a review of current clinical STAR practice in Europe, a comprehensive questionnaire was performed at project start. The STOPSTORM Institutions' experience in VT catheter ablation (83% ≥ 20 ann.) and stereotactic body radiotherapy (59% > 200 ann.) was adequate, and 84 STAR treatments were performed until project launch, while 8/22 centres already recruited VT patients in national clinical trials. The majority currently base their target definition on mapping during VT (96%) and/or pace mapping (75%), reduced voltage areas (63%), or late ventricular potentials (75%) during sinus rhythm. The majority currently apply a single-fraction dose of 25 Gy while planning techniques and dose prescription methods vary greatly. The current clinical STAR practice in the STOPSTORM consortium highlights potential areas of optimization and harmonization for substrate mapping, target delineation, motion management, dosimetry, and QA, which will be addressed in the various WPs. © The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology.

Published
2023

18. European Society of Cardiology quality indicators for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death

Author

Aktaa, S, Tzeis, S, Gale, C, Ackerman, M, Arbelo, E, Behr, E, Crotti, L, D'Avila, A, de Chillou, C, Deneke, T, Figueiredo, M, Friede, T, Leclercq, C, Merino, J, Semsarian, C, Verstrael, A, Zeppenfeld, K, Tfelt-Hansen, J, Reichlin, T, Aktaa, Suleman, Tzeis, Stylianos, Gale, Chris P, Ackerman, Michael J, Arbelo, Elena, Behr, Elijah R, Crotti, Lia, d'Avila, Andre, de Chillou, Christian, Deneke, Thomas, Figueiredo, Márcio, Friede, Tim, Leclercq, Christophe, Merino, Jose L, Semsarian, Chris, Verstrael, Axel, Zeppenfeld, Katja, Tfelt-Hansen, Jacob, Reichlin, Tobias, Aktaa, S, Tzeis, S, Gale, C, Ackerman, M, Arbelo, E, Behr, E, Crotti, L, D'Avila, A, de Chillou, C, Deneke, T, Figueiredo, M, Friede, T, Leclercq, C, Merino, J, Semsarian, C, Verstrael, A, Zeppenfeld, K, Tfelt-Hansen, J, Reichlin, T, Aktaa, Suleman, Tzeis, Stylianos, Gale, Chris P, Ackerman, Michael J, Arbelo, Elena, Behr, Elijah R, Crotti, Lia, d'Avila, Andre, de Chillou, Christian, Deneke, Thomas, Figueiredo, Márcio, Friede, Tim, Leclercq, Christophe, Merino, Jose L, Semsarian, Chris, Verstrael, Axel, Zeppenfeld, Katja, Tfelt-Hansen, Jacob, and Reichlin, Tobias

Abstract

To develop a suite of quality indicators (QIs) for the management of patients with ventricular arrhythmias (VA) and the prevention of sudden cardiac death (SCD). The Working Group comprised experts in heart rhythm management including Task Force members of the 2022 European Society of Cardiology (ESC) Clinical Practice Guidelines for the management of patients with VA and the prevention of SCD, members of the European Heart Rhythm Association, international experts, and a patient representative. We followed the ESC methodology for QI development, which involves (i) the identification of the key domains of care for the management of patients with VA and the prevention of SCD by constructing a conceptual framework of care, (ii) the development of candidate QIs by conducting a systematic review of the literature, (iii) the selection of the final set of QIs using a modified-Delphi method, and (iv) the evaluation of the feasibility of the developed QIs. We identified eight domains of care for the management of patients with VA and the prevention of SCD: (i) structural framework, (ii) screening and diagnosis, (iii) risk stratification, (iv) patient education and lifestyle modification, (v) pharmacological treatment, (vi) device therapy, (vii) catheter ablation, and (viii) outcomes, which included 17 main and 4 secondary QIs across these domains. Following a standardized methodology, we developed 21 QIs for the management of patients with VA and the prevention of SCD. The implementation of these QIs will improve the care and outcomes of patients with VA and contribute to the prevention of SCD.

Published
2023

19. Recurrences of ventricular tachycardia after stereotactic arrhythmia radioablation arise outside the treated volume: analysis of the swiss cohort

Author

Siklody, C Herrera; https://orcid.org/0000-0001-6881-3073, Schiappacasse, L; https://orcid.org/0000-0001-7621-1662, Jumeau, R; https://orcid.org/0000-0002-0098-8835, Reichlin, T; https://orcid.org/0000-0002-7197-8415, Saguner, A M; https://orcid.org/0000-0003-1896-0803, Andratschke, N; https://orcid.org/0000-0003-3647-5916, Elicin, O; https://orcid.org/0000-0002-6996-0646, Schreiner, F, Kovacs, B; https://orcid.org/0000-0002-7972-5199, Mayinger, M, Huber, A; https://orcid.org/0000-0001-6146-8238, Verhoeff, J J C; https://orcid.org/0000-0001-9673-0793, Pascale, P; https://orcid.org/0000-0001-7328-2481, Solana Muñoz, J; https://orcid.org/0000-0002-2633-7248, Luca, A; https://orcid.org/0000-0002-0040-8191, Domenichini, G, Moeckli, R; https://orcid.org/0000-0002-5885-934X, Bourhis, J, Ozsahin, E M; https://orcid.org/0000-0003-2947-5360, Pruvot, E; https://orcid.org/0000-0003-1386-9285, Siklody, C Herrera; https://orcid.org/0000-0001-6881-3073, Schiappacasse, L; https://orcid.org/0000-0001-7621-1662, Jumeau, R; https://orcid.org/0000-0002-0098-8835, Reichlin, T; https://orcid.org/0000-0002-7197-8415, Saguner, A M; https://orcid.org/0000-0003-1896-0803, Andratschke, N; https://orcid.org/0000-0003-3647-5916, Elicin, O; https://orcid.org/0000-0002-6996-0646, Schreiner, F, Kovacs, B; https://orcid.org/0000-0002-7972-5199, Mayinger, M, Huber, A; https://orcid.org/0000-0001-6146-8238, Verhoeff, J J C; https://orcid.org/0000-0001-9673-0793, Pascale, P; https://orcid.org/0000-0001-7328-2481, Solana Muñoz, J; https://orcid.org/0000-0002-2633-7248, Luca, A; https://orcid.org/0000-0002-0040-8191, Domenichini, G, Moeckli, R; https://orcid.org/0000-0002-5885-934X, Bourhis, J, Ozsahin, E M; https://orcid.org/0000-0003-2947-5360, and Pruvot, E; https://orcid.org/0000-0003-1386-9285

Abstract

BACKGROUND AND AIMS Stereotactic arrhythmia radioablation (STAR) has been recently introduced for the management of therapy-refractory ventricular tachycardia (VT). VT recurrences have been reported after STAR but the mechanisms remain largely unknown. We analyzed recurrences in our patients after STAR. METHODS From 09.2017 to 01.2020, 20 patients (68±8y, LVEF 37±15%) suffering from refractory VT were enrolled, 16/20 with a history of at least 1 electrical storm. Before STAR, an invasive electro-anatomical mapping (Carto3) of the VT substrate was performed. A mean dose of 23±2Gy was delivered to the planning target volume (PTV). RESULTS The median ablation volume was 26 ml (range 14-115) and involved the interventricular septum in 75% of patients. During the first 6 months after STAR, VT burden decreased by 92% (median value, from 108 to 10 VT/semester). After a median follow-up of 25 months, 12/20 (60%) developed a recurrence and underwent a redo ablation. VT recurrence was located in proximity of the treated substrate in 9 cases, remote from the PTV in 3 cases and involved a larger substrate over ≥3 LV segments in 2 cases. No recurrences occurred inside the PTV. Voltage measurements showed a significant decrease in both bipolar and unipolar signal amplitude after STAR. CONCLUSION STAR is a new tool available for the treatment of VT, allowing for a significant reduction of VT burden. VT recurrences are common during follow-up, but no recurrences were observed inside the PTV. Local efficacy was supported by a significant decrease in both bipolar and unipolar signal amplitude.

Published
2023

22. Pulsed-field- vs. cryo- vs. radiofrequency ablation: one-year recurrence rates after pulmonary vein isolation in patients with paroxysmal atrial fibrillation

Author

Kueffer, T, primary, Madaffari, A, additional, Muehl, A, additional, Maurhofer, J, additional, Stefenova, A, additional, Seiler, J, additional, Thalmann, G, additional, Kozhuharov, N A, additional, Servatius, H, additional, Tanner, H, additional, Haeberlin, A, additional, Baldinger, S H, additional, Noti, F, additional, Roten, L, additional, and Reichlin, T, additional

Published
2023
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23. QRS complex and T wave planarity for the prediction of death and appropriate shocks in recipients of prophylactic implantable defibrillators

Author

Novotny, T, primary, Hnatkova, K, additional, Andrsova, I, additional, Vandenberk, B, additional, Sprenkeler, D J, additional, Junttila, J, additional, Reichlin, T, additional, Schloegl, S, additional, Friede, T, additional, Bauer, A, additional, Willems, R, additional, Schmidt, G, additional, Sticherling, C, additional, Zabel, M, additional, and Malik, M, additional

Published
2023
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25. Pulmonary vein reconnection rates and lesion regression during repeat procedures in patients with recurrent arrhythmias after pulsed field ablation pulmonary vein isolation

Author

Kueffer, T, primary, Madaffari, A, additional, Muehl, A, additional, Seiler, J, additional, Thalmann, G, additional, Servatius, H, additional, Kozhuharov, N A, additional, Tanner, H, additional, Haeberlin, A, additional, Noti, A, additional, Baldinger, S H, additional, Roten, L, additional, and Reichlin, T, additional

Published
2023
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29. Recurrences of ventricular tachycardia after stereotactic arrhythmia radioablation arise outside the treated volume: analysis of the Swiss cohort

Author

Herrera Siklody, C, primary, Schiappacasse, L, additional, Jumeau, R, additional, Reichlin, T, additional, Saguner, A, additional, Andratschke, N, additional, Elicin, O, additional, Kovacs, B, additional, Mayinger, M, additional, Huber, A, additional, Le Bloa, M, additional, Teres Castillo, C, additional, Domenichini, G, additional, Bourhis, J, additional, and Pruvot, E, additional

Published
2023
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30. Pulsed-field ablation for redo procedures after failed radiofrequency or cryo ablation for atrial fibrillation

Author

Tanner, H, primary, Kueffer, T, additional, Madaffari, A, additional, Muehl, A, additional, Maurhofer, J, additional, Seiler, J, additional, Thalmann, G, additional, Servatius, H, additional, Kozhuharov, N, additional, Noti, F, additional, Haeberlin, A, additional, Baldinger, S H, additional, Roten, L, additional, and Reichlin, T, additional

Published
2023
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31. Use of copeptin and high-sensitive cardiac troponin T for diagnosis and prognosis in patients with diabetes mellitus and suspected acute myocardial infarction

Author

Zellweger, C., Wildi, K., Twerenbold, R., Reichlin, T., Naduvilekoot, A., Neuhaus, J.D., Balmelli, C., Gabutti, M., Al Afify, A., Ballarino, P., Jäger, C., Druey, S., Hillinger, P., Haaf, P., Vilaplana, C., Darbouret, B., Ebmeyer, S., Rubini Gimenez, M., Moehring, B., Osswald, S., and Mueller, C.

Published
2015
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32. Sex-Related Differences in Cardiac Channelopathies: Implications for Clinical Practice

Author

Asatryan, B, Yee, L, Ben-Haim, Y, Dobner, S, Servatius, H, Roten, L, Tanner, H, Crotti, L, Skinner, J, Remme, C, Chevalier, P, Medeiros-Domingo, A, Behr, E, Reichlin, T, Odening, K, Krahn, A, Asatryan B., Yee L., Ben-Haim Y., Dobner S., Servatius H., Roten L., Tanner H., Crotti L., Skinner J. R., Remme C. A., Chevalier P., Medeiros-Domingo A., Behr E. R., Reichlin T., Odening K. E., Krahn A. D., Asatryan, B, Yee, L, Ben-Haim, Y, Dobner, S, Servatius, H, Roten, L, Tanner, H, Crotti, L, Skinner, J, Remme, C, Chevalier, P, Medeiros-Domingo, A, Behr, E, Reichlin, T, Odening, K, Krahn, A, Asatryan B., Yee L., Ben-Haim Y., Dobner S., Servatius H., Roten L., Tanner H., Crotti L., Skinner J. R., Remme C. A., Chevalier P., Medeiros-Domingo A., Behr E. R., Reichlin T., Odening K. E., and Krahn A. D.

Abstract

Sex-related differences in prevalence, clinical presentation, and outcome of cardiac channelopathies are increasingly recognized, despite their autosomal transmission and hence equal genetic predisposition among sexes. In congenital long-QT syndrome, adult women carry a greater risk for Torsades de pointes and sudden cardiac death than do men. In contrast, Brugada syndrome is observed predominantly in adult men, with a considerably higher risk of arrhythmic sudden cardiac death in adult men than in women. In both conditions, the risk for arrhythmias varies with age. Sex-associated differences appear less evident in other cardiac channelopathies, likely a reflection of their rare(r) occurrence and our limited knowledge. In several cardiac channelopathies, sex-specific predictors of outcome have been identified. Together with genetic and environmental factors, sex hormones contribute to the sex-related disparities in cardiac channelopathies through modulation of the expression and function of cardiac ion channels. Despite these insights, essential knowledge gaps exist in the mechanistic understanding of these differences, warranting further investigation. Precise application of the available knowledge may improve the individualized care of patients with cardiac channelopathies. Promoting the reporting of sex-related phenotype and outcome parameters in clinical and experimental studies and advancing research on cardiac channelopathy animal models should translate into improved patient outcomes. This review provides a critical digest of the current evidence for sex-related differences in cardiac channelopathies and emphasizes their clinical implications and remaining gaps requiring further research.

Published
2021

33. Bipolar ablation of refractory ventricular arrhythmias using a novel dedicated adapter. A multicenter study

Author

Futyma, P, primary, Bordignon, S, additional, Imnadze, G, additional, Peichl, P, additional, Seidl, S, additional, Kueffer, T, additional, Chen, S, additional, Zarebski, L, additional, Martinek, M, additional, Puererfellner, H, additional, Kautzner, J, additional, Reichlin, T, additional, Sommer, P, additional, Chun, J K R, additional, and Schmidt, B, additional

Published
2022
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35. 2022 ESC guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death

Author

Zeppenfeld, K., Tfelt-Hansen, J., Riva, M. de, Winkel, B.G., Behr, E.R., Blom, N.A., Charron, P., Corrado, D., Dagres, N., Chillou, C. de, Eckardt, L., Friede, T., Haugaa, K.H., Hocini, M., Lambiase, P.D., Marijon, E., Merino, J.L., Peichl, P., Priori, S.G., Reichlin, T., Schulz-Menger, J., Sticherling, C., Tzeis, S., Verstrael, A., Volterrani, M., Cikes, M., Kirchhof, P., Abdelhamid, M., Aboyans, V., Arbelo, E., Arribas, F., Asteggiano, R., Basso, C., Bauer, A., Bertaglia, E., Biering-Sorensen, T., Blomstrom-Lundqvist, C., Borger, M.A., Celutkiene, J., Cosyns, B., Falk, V., Fauchier, L., Gorenek, B., Halvorsen, S., Hatala, R., Heidbuchel, H., Kaab, S., Konradi, A., Koskinas, K.C., Kotecha, D., Landmesser, U., Lewis, B.S., Linhart, A., Lochen, M.L., Lund, L.H., Metzner, A., Mindham, R., Nielsen, J.C., Norekval, T.M., Patten, M., Prescott, E., Rakisheva, A., Remme, C.A., Roca-Luque, I., Sarkozy, A., Scherr, D., Sitges, M., Touyz, R.M., Mieghem, N. van, Velagic, V., Viskin, S., Volders, P.G.A., Task Force Members, and ESC Scientific Document Group

Subjects
Genetic testing, Cardiac magnetic resonance, Sudden death, Ventricular tachycardia, Primary electrical disease, Guidelines, Recommendations, Chronic coronary artery disease, Risk calculator, Sudden cardiac death, Implantable cardioverter defibrillator, Ventricular arrhythmia, Catheter ablation, Anti-arrhythmic drugs, Ventricular fibrillation, Cardiomyopathies, Risk stratification, Premature ventricular complex
Published
2022

36. European Society of Cardiology quality indicators for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death Developed in collaboration with the European Heart Rhythm Association of the European Society of Cardiology

Author

Aktaa, S., Tzeis, S., Gale, C.P., Ackerman, M.J., Arbelo, E., Behr, E.R., Crotti, L., d'Avila, A., Chillou, C. de, Denekel, T., Figueiredo, M., Friede, T., Leclercq, C., Merino, J.L., Semsarian, C., Verstrael, A., Zeppenfeld, K., Tfelt-Hansen, J., Reichlin, T., University of Leeds, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Consejo Superior de Investigaciones Científicas [Spain] (CSIC), Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), Università degli Studi di Milano-Bicocca = University of Milano-Bicocca (UNIMIB), Centre Hospitalier Universitaire de Nancy (CHU Nancy), Universidade Estadual de Campinas = University of Campinas (UNICAMP), Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Mayo Clinic Windland Smith Rice Comprehensive Sudden Cardiac Death Program, and National Health and Medical Research Council (NHMRC) Practitioner Fellowship [1154992]

Subjects
Treatment, Sudden cardiac death, Ventricular arrhythmias, [SDV.IB]Life Sciences [q-bio]/Bioengineering, Quality indicators, Accountability, Outcomes, Clinical practice guidelines
Abstract

International audience; Aims To develop a suite of quality indicators (QIs) for the management of patients with ventricular arrhythmias (VA) and the prevention of sudden cardiac death (SCD). Methods and results The Working Group comprised experts in heart rhythm management including Task Force members of the 2022 European Society of Cardiology (ESC) Clinical Practice Guidelines for the management of patients with VA and the prevention of SCD, members of the European Heart Rhythm Association, international experts, and a patient representative. We followed the ESC methodology for QI development, which involves (i) the identification of the key domains of care for the management of patients with VA and the prevention of SCD by constructing a conceptual framework of care, (ii) the development of candidate QIs by conducting a systematic review of the literature, (iii) the selection of the final set of QIs using a modified-Delphi method, and (iv) the evaluation of the feasibility of the developed QIs. We identified eight domains of care for the management of patients with VA and the prevention of SCD: (i) structural framework, (ii) screening and diagnosis, (iii) risk stratification, (iv) patient education and lifestyle modification, (v) pharmacological treatment, (vi) device therapy, (vii) catheter ablation, and (viii) outcomes, which included 17 main and 4 secondary QIs across these domains. Conclusion Following a standardized methodology, we developed 21 QIs for the management of patients with VA and the prevention of SCD. The implementation of these QIs will improve the care and outcomes of patients with VA and contribute to the prevention of SCD.

Published
2022
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37. Q waves are the strongest electrocardiographic variable associated with primary prophylactic implantable cardioverter-defibrillator benefit:a prospective multicentre study

Author

Pelli, A. (Ari), Junttila, M. J. (M. Juhani), Kenttä, T. V. (Tuomas, V), Schlogl, S. (Simon), Zabel, M. (Markus), Malik, M. (Marek), Reichlin, T. (Tobias), Willems, R. (Rik), Vos, M. A. (Marc A.), Harden, M. (Markus), Friede, T. (Tim), Sticherling, C. (Christian), Huikuri, H. V. (Heikki, V), the EU-CERT-ICD Study Investigators, Pelli, A. (Ari), Junttila, M. J. (M. Juhani), Kenttä, T. V. (Tuomas, V), Schlogl, S. (Simon), Zabel, M. (Markus), Malik, M. (Marek), Reichlin, T. (Tobias), Willems, R. (Rik), Vos, M. A. (Marc A.), Harden, M. (Markus), Friede, T. (Tim), Sticherling, C. (Christian), Huikuri, H. V. (Heikki, V), and the EU-CERT-ICD Study Investigators

Abstract

Aim: The association of standard 12-lead electrocardiogram (ECG) markers with benefits of the primary prophylactic implantable cardioverter-defibrillator (ICD) has not been determined in the contemporary era. We analysed traditional and novel ECG variables in a large prospective, controlled primary prophylactic ICD population to assess the predictive value of ECG in terms of ICD benefit. Methods and results: Electrocardiograms from 1477 ICD patients and 700 control patients (EU-CERT-ICD; non-randomized, controlled, prospective multicentre study; ClinicalTrials.gov Identifier: NCT02064192), who met ICD implantation criteria but did not receive the device, were analysed. The primary outcome was all-cause mortality. In ICD patients, the co-primary outcome of first appropriate shock was used. Mean follow-up time was 2.4 ± 1.1 years to death and 2.3 ± 1.2 years to the first appropriate shock. Pathological Q waves were associated with decreased mortality in ICD patients [hazard ratio (HR) 0.54, 95% confidence interval (CI) 0.35–0.84; P < 0.01] and patients with pathological Q waves had significantly more benefit from ICD (HR 0.44, 95% CI 0.21–0.93; P = 0.03). QTc interval increase taken as a continuous variable was associated with both mortality and appropriate shock incidence, but commonly used cut-off values, were not statistically significantly associated with either of the outcomes. Conclusion: Pathological Q waves were a strong ECG predictor of ICD benefit in primary prophylactic ICD patients. Excess mortality among Q wave patients seems to be due to arrhythmic death which can be prevented by ICD., EU-CERT-ICD The EU-CERT-ICD Study Investigators: Elena Arbelo, MD, Axel Bauer MD, Frieder Braunschweig MD PhD, Josep Brugada MD, PhD, David Conen MD, Iwona Cygankiewicz MD, Michael Dommasch MD, Christian Eick, MD, Panagiota Flevari MD, Tim Friede PhD, Jan Galuszka MD, Jim Hansen MD, Robert Hatala MD, Markus Harden PhD, Katerina Hnatkova PhD, Heikki V. Huikuri MD, Juhani M. Junttila, MD PhD, Stefan Kääb MD, Gabriela Kaliska MD, Jaroslaw D. Kasprzak MD, Andreas Katsimardos MD, Milan Kozak MD, Tomasz Kuczejko MD, Andrzej Lubinski MD, Jozef Martinek PhD, Béla Merkely MD, PhD, Tomáš Novotný MD, Marek Malik PhD MD, Peter Perge MD, Burkert Pieske MD, Pyotr Platonov MD PhD, Pawel Ptaczyński, MD, Dariusz Qavoq MD, L. Rotkvić, MD, Zoltan Sallo MD, Simon Schlögl MD, Georg Schmidt MD, Moritz Sinner, MD, Rajeeva Sritharan MSc, Stefan Stefanow MD, Christian Sticherling MD PhD, Jesper Hastrup Svendsen MD DMSc, Martin Svetlosak MD, Janko Szavits-Nossan MD, Milos Taborsky MD, Anton Tuinenburg, MD, Bert Vandenberk MD, Marc A. Vos PhD, Rik Willems MD PhD, Stefan N Willich MD PhD, Christian Wolpert MD, Markus Zabel MD, Ante Anic, MD, Zoran Bakotic MD, Steffen Behrens MD, Dieter Bimmel MD, Sandro Brusich MD, Rüdiger Dissmann MD, Gerian Grönefeld, MD, Przemyzlav Guzik MD, Svetoslav Iovev MD, Zrinka Jurisic MD, Thomas Klingenheben, MD, Nikola Pavlović MD, Joachim Seegers MD, Robert H.G. Schwinger MD, Tchavdar Shalganov MD, Vassil Traykov MD, Vasil Velchev MD.

Published
2022

38. Comparison of the accuracy of contact force measurement in four commercially available force-sensing ablation catheters

Author

Kueffer, T, primary, Haeberlin, A, additional, Knecht, S, additional, Baldinger, SH, additional, Servatius, H, additional, Madaffari, A, additional, Seiler, J, additional, Muehl, A, additional, Franzeck, F, additional, Asatryan, B, additional, Noti, F, additional, Tanner, H, additional, Roten, L, additional, and Reichlin, T, additional

Published
2022
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39. Nurse-led compared to physician-led implant of cardiac monitors

Author

Steinhauer, B, primary, Spicher, J, additional, Aerschmann, S, additional, Ambord, N, additional, Bartkowiak, J, additional, Servatius, H, additional, Noti, F, additional, Seiler, J, additional, Baldinger, S, additional, Haeberlin, A, additional, Madaffari, A, additional, Tanner, H, additional, Reichlin, T, additional, Roten, L, additional, and Duetschler, S, additional

Published
2022
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42. Validation of a multipolar pulsed field ablation catheter for endpoint assessment in pulmonary vein isolation procedures

Author

Kueffer, T, primary, Baldinger, SH, additional, Servatius, H, additional, Madaffari, A, additional, Seiler, J, additional, Muehl, A, additional, Franzeck, F, additional, Thalmann, G, additional, Asatryan, B, additional, Haeberlin, A, additional, Noti, F, additional, Tanner, H, additional, Roten, L, additional, and Reichlin, T, additional

Published
2022
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43. Electrophysiological differences of deep sedation with dexmedetomidine versus propofol

Author

Servatius, H, primary, Kueffer, T, additional, Baldinger, SH, additional, Asatryan, B, additional, Seiler, J, additional, Tanner, H, additional, Novak, J, additional, Noti, F, additional, Haeberlin, A, additional, Madaffari, A, additional, Muehl, A, additional, Branca, M, additional, Duetschler, S, additional, Reichlin, T, additional, and Roten, L, additional

Published
2022
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45. Incidental arrhythmias during atrial fibrillation screening in a hospital-based patient population

Author

Goulouti, E, primary, Lam, A, additional, Nozica, N, additional, Elchinova, E, additional, Spirito, A, additional, Servatius, H, additional, Noti, F, additional, Seiler, J, additional, Baldinger, S, additional, Haeberlin, A, additional, Babken, A, additional, Franzeck, F, additional, Tanner, H, additional, Reichlin, T, additional, and Roten, L, additional

Published
2022
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46. Pulsed field ablation of atrial fibrillation: recurrence rate after first pulmonary vein isolation and first insights into durability at redo procedures

Author

Kueffer, T, primary, Seiler, J, additional, Madaffari, A, additional, Muehl, A, additional, Stettler, R, additional, Asatryan, B, additional, Haeberlin, A, additional, Noti, F, additional, Servatius, H, additional, Tanner, H, additional, Baldinger, SH, additional, Roten, L, additional, and Reichlin, T, additional

Published
2022
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49. Gender gap in study inclusion: Insights from the STAR-FIB cohort study

Author

Tanner, H, primary, Goulouti, E, additional, Lam, A, additional, Elchinova, E, additional, Nozica, N, additional, Servatius, H, additional, Noti, F, additional, Seiler, J, additional, Baldinger, SH, additional, Haeberlin, A, additional, Franzeck, F, additional, Asatryan, B, additional, Reichlin, T, additional, and Roten, L, additional

Published
2022
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50. 2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy

Author

Glikson, M., Nielsen, J. C., Kronborg, M. B., Michowitz, Y., Auricchio, A., Barbash, I. M., Barrabes, J. A., Boriani, G., Braunschweig, F., Brignole, M., Burri, H., Coats, A. J. S., Deharo, J. -C., Delgado, V., Diller, G. -P., Israel, C. W., Keren, A., Knops, R. E., Kotecha, D., Leclercq, C., Merkely, B., Starck, C., Thylen, I., Tolosana, J. M., Leyva, F., Linde, C., Abdelhamid, M., Aboyans, V., Arbelo, E., Asteggiano, R., Baron-Esquivias, G., Bauersachs, J., Biffi, M., Birgersdotter-Green, U., Bongiorni, M. G., Borger, M. A., Celutkiene, J., Cikes, M., Daubert, J. -C., Drossart, I., Ellenbogen, K., Elliott, P. M., Fabritz, L., Falk, V., Fauchier, L., Fernandez-Aviles, F., Foldager, D., Gadler, F., De Vinuesa, P. G. G., Gorenek, B., Guerra, J. M., Hermann Haugaa, K., Hendriks, J., Kahan, T., Katus, H. A., Konradi, A., Koskinas, K. C., Law, H., Lewis, B. S., Linker, N. J., Lochen, M. -L., Lumens, J., Mascherbauer, J., Mullens, W., Nagy, K. V., Prescott, E., Raatikainen, P., Rakisheva, A., Reichlin, T., Ricci, R. P., Shlyakhto, E., Sitges, M., Sousa-Uva, M., Sutton, R., Suwalski, P., Svendsen, J. H., Touyz, R. M., Van Gelder, I. C., Vernooy, K., Waltenberger, J., Whinnett, Z., Witte, K. K., Qoriany, A., Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), and Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)

Subjects
Pacemaker, Artificial, Cardiac pacing, medicine.medical_treatment, [SDV]Life Sciences [q-bio], Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], cardiac resynchronization therapy, heart failure, temporary pacing, law.invention, law, atrial fibrillation, 610 Medicine & health, ComputingMilieux_MISCELLANEOUS, biology, Cardiac Pacing, Artificial, Syncope (genus), Atrial fibrillation, syncope, Cardiology, cardiovascular system, medicine.symptom, guidelines, cardiac pacing, pacemaker, conduction system pacing, pacing indications, alternate site pacing, complications, pacing in TAVI, bradycardia, Cardiology and Cardiovascular Medicine, Bradycardia, medicine.medical_specialty, Cardiac resynchronization therapy, Guidelines, Physiology (medical), Internal medicine, medicine, Humans, Task force, business.industry, Stroke Volume, 1103 Clinical Sciences, medicine.disease, biology.organism_classification, Heart Rhythm, Cardiovascular System & Hematology, Heart failure, Artificial cardiac pacemaker, business, Atrioventricular block
Abstract

These are the clinical practice guidelines of the European Society of Cardiology on cardiac pacing and cardiac resynchronization therapy, from 2021.

Published
2022
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