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270 results on '"Rawi, Reda"'

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1. Cholesterol reduction by immunization with a PCSK9 mimic

2. Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site

3. Protective human monoclonal antibodies target conserved sites of vulnerability on the underside of influenza virus neuraminidase

4. Soluble prefusion-closed HIV-envelope trimers with glycan-covered bases

5. HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide

7. Cryo-EM structures of prefusion SIV envelope trimer

8. Vaccine elicitation and structural basis for antibody protection against alphaviruses

9. Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses

10. A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination

11. Mutational fitness landscapes reveal genetic and structural improvement pathways for a vaccine-elicited HIV-1 broadly neutralizing antibody

12. Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies

13. Rapid Emergence and Evolution of SARS-CoV-2 Variants in Advanced HIV Infection

16. Extraordinary Titer and Broad Anti-SARS-CoV-2 Neutralization Induced by Stabilized RBD Nanoparticles from Strain BA.5.

17. Enhancing Anti-SARS-CoV-2 Neutralizing Immunity by Genetic Delivery of Enveloped Virus-like Particles Displaying SARS-CoV-2 Spikes

18. Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen

19. Improved pharmacokinetics of HIV-neutralizing VRC01-class antibodies achieved by reduction of net positive charge on variable domain

20. Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization

22. Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

23. Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency

26. Antibodies as drugs—a Keystone Symposia report

27. Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability

28. Structure of an influenza group 2-neutralizing antibody targeting the hemagglutinin stem supersite

30. Structural basis for llama nanobody recognition and neutralization of HIV-1

31. Highly protective antimalarial antibodies via precision library generation and yeast display screening

32. Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site

34. In Silico Improvement of Highly Protective Anti-Malarial Antibodies

35. Development of Neutralization Breadth against Diverse HIV‐1 by Increasing Ab–Ag Interface on V2

36. Vaccine-elicitation of cross-group neutralizing protective antibodies to influenza A viruses

37. Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies

39. Blocking α 4 β 7 integrin delays viral rebound in SHIV SF162P3 -infected macaques treated with anti-HIV broadly neutralizing antibodies

40. Augmenting Neutralization breadth against Diverse HIV-1 by increasing the Ab-Ag interface on V2

41. Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography

42. Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses

43. Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite

45. Automated Design by Structure-Based Stabilization and Consensus Repair to Achieve Prefusion-Closed Envelope Trimers in a Wide Variety of HIV Strains

46. Identification and Structure of a Multidonor Class of Head-Directed Influenza-Neutralizing Antibodies Reveal the Mechanism for Its Recurrent Elicitation

47. Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses

48. Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition

49. Impact of glycan positioning on HIV-1 Env glycan shield density, function, and antibody recognition

50. VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage

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