9 results on '"Portia Ndlovu"'
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2. Comparison of the specificities of IgG, IgG-subclass, IgA and IgM reactivities in African and European HIV-infected individuals with an HIV-1 clade C proteome-based array.
- Author
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Daniela Gallerano, Portia Ndlovu, Ian Makupe, Margarete Focke-Tejkl, Kerstin Fauland, Eva Wollmann, Elisabeth Puchhammer-Stöckl, Walter Keller, Elopy Sibanda, and Rudolf Valenta
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Medicine ,Science - Abstract
A comprehensive set of recombinant proteins and peptides of the proteome of HIV-1 clade C was prepared and purified and used to measure IgG, IgG-subclass, IgA and IgM responses in HIV-infected patients from Sub-Saharan Africa, where clade C is predominant. As a comparison group, HIV-infected patients from Europe were tested. African and European patients showed an almost identical antibody reactivity profile in terms of epitope specificity and involvement of IgG, IgG subclass, IgA and IgM responses. A V3-peptide of gp120 was identified as major epitope recognized by IgG1>IgG2 = IgG4>IgG3, IgA>IgM antibodies and a C-terminal peptide represented another major peptide epitope for the four IgG subclasses. By contrast, gp41-derived-peptides were mainly recognized by IgG1 but not by the other IgG subclasses, IgA or IgM. Among the non-surface proteins, protease, reverse transcriptase+RNAseH, integrase, as well as the capsid and matrix proteins were the most frequently and strongly recognized antigens which showed broad IgG subclass and IgA reactivity. Specificities and magnitudes of antibody responses in African patients were stable during disease and antiretroviral treatment, and persisted despite severe T cell loss. Using a comprehensive panel of gp120, gp41 peptides and recombinant non-surface proteins of HIV-1 clade C we found an almost identical antibody recognition profile in African and European patients regarding epitopes and involved IgG-sublass, IgA- and IgM-responses. Immune recognition of gp120 peptides and non-surface proteins involved all four IgG subclasses and was indicative of a mixed Th1/Th2 immune response. The HIV-1 clade C proteome-based test allowed diagnosis and monitoring of antibody responses in the course of HIV-infections and assessment of isotype and subclass responses.
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- 2015
- Full Text
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3. Ballast Water Utopia and Some Environmental Protection Ideas
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Portia Ndlovu, Fikile, primary
- Published
- 2022
- Full Text
- View/download PDF
4. Ballast Water Utopia and Some Environmental Protection Ideas
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Portia, Ndlovu, Fikile
- Abstract
An environmental protection plan that would resemble a true utopia might still be distant however, employing advanced methods and innovation that will get the global community on the road to the best marine and other environmental protections should be every generation’s intent. Ballast water management as related to shipping, trade, and the marine world as a special concern of this paper has been one of the most notable innovation drivers in the maritime space in the last couple of decades in order to close doors to the dangers of introducing new aquatic invasive species in sensitive environments around the world (bio invasions). This paper aims to selectively survey some established ballast water management methods reimagined by the latest innovations reflecting on some latest developments. The world is constantly facing troubling concerns over environmental protection issues particularly related to marine and maritime related endeavors. For example, what it may mean to lose many Russian scientists that are involved in arctic research as a result of the Russia-Ukraine conflict, especially with ship traffic and ballast water management slated to be more and more of a concern in that area as shipping channels become more open in that region.
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- 2022
5. IMPACT OF LOCAL ECONOMIC DEVELOPMENT PROGRAMMES ON LIVELIHOOD: EVIDENCE FROM MPUMALANGA, SOUTH AFRICA
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Isaac Agholor, Ogujiuba Kanayo, and Portia Ndlovu
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HF5001-6182 ,Inequality ,Poverty ,media_common.quotation_subject ,Developing country ,Local economic development ,Livelihood ,Economics as a science ,Quality of life (healthcare) ,Unemployment ,Development economics ,Economics ,Business ,HB71-74 ,General Economics, Econometrics and Finance ,media_common - Abstract
Extraordinary levels of unemployment, poverty and inequality perseveres in South Africa, which in itself is a risk for economic development. Initiatives such as Local Economic Development (LED), globally acknowledged, have been adopted to solve the crisis. LED in its simplest practice is about local people uniting to achieve a better quality of life. Nevertheless, effects of LED are still contentious in developing economies and especially South Africa because of the increased level of poverty amongst supposed beneficiaries of LED. This article evaluates the impact of a LED initiative (EPWP) on reducing the triple challenges facing South Africa. A mixed method approach and a paired-sample t-test was performed to determine the effect of LED. Between time 1[M=17.91, SD=2.68] to time 2[M=20.06, SD=3.43, t(44)=5.1429, pKeywords: EPWP, LED, Livelihood, PovertyJEL Classifications: O20, O21, O38DOI: https://doi.org/10.32479/ijefi.11589
- Published
- 2021
6. SOUTH AFRICAN MARINE INSURANCE LAW: THE CURRENT STATE OF OUR DRAFT MARINE INSURANCE BILL AND THE EFFECT OF ITS PROMULGATION ON THE SOUTH AFRICAN MARINE INSURANCE INDUSTRY
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null Portia Ndlovu
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General Earth and Planetary Sciences ,General Environmental Science - Abstract
In 1997 a draft proposal for a Marine Insurance Act was prepared as a new South African statute in response to a call for the development of marine insurance by legal practitioners, academics, various members of the Maritime Law Association and other members of various Marine Underwriting bodies (the draft bill was redrafted in 1997 by its main draftsman Adv Douglas Shaw QC). The draft legislation, tends to adopt the form and structure of the English Marine Insurance Act 1906 (6 Edw 7c 41), with minor differences. For instance, in keeping with the South African law on insurance, the draft Act excludes the English law concept “uberrima fides”, which has been rejected as an alien concept under South African insurance law. It is essential for legislature to review the status of the bill as marine insurance forms the oldest part of our well established maritime economy. Developments in marine insurance laws will enable South Africa to participate more meaningfully from a legislative point of view in the international arena. The draft bill is a useful tool in determining the probable future direction of the developments in South African marine insurance, however, this draft legislation has not been promulgated. It is possible to underestimate the usefulness of such a code since ten years have passed since the bill’s last re-draft. It is proposed in this article that there is a need for codified South African Marine Insurance Law and that perhaps the legislature should reopen the debate on the bill and consider it in order to hasten the process of its promulgation. Further, if such a statute is developed it must be unique to South Africa in that it must reflect a balance between the modern Roman-Dutch law as applied by our courts in marine insurance matters while useful English law concepts are also reflected for the purposes of international uniformity. However, if capturing such a dichotomy in the draft bill proves to be against international marine insurance trends, perhaps the best way forward is to promulgate the existing draft Act as is. What must be achieved in the end is that South African Marine Insurance Law must lose its legal research status of being the “Cinderella” of all insurances and have positive laws that govern it specifically in the form of a South African Marine Insurance Act.
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- 2022
7. PRIVATE INTERNATIONAL LAW / CONFLICT OF LAWS AND DIAMOND TRADE
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Fikile Portia Ndlovu
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Identification (information) ,Conflict of laws ,Law ,Political science ,Taste (sociology) ,media_common.quotation_subject ,Conflict resolution research ,Choice of law ,Relevance (law) ,Context (language use) ,Relation (history of concept) ,media_common - Abstract
Any researcher of South African diamond laws would find it inevitable that such research discusses the relationship between international diamond transactions and conflict of laws. This is particularly evident in cases where legal disputes have arisen pertaining to such transactions. This article will make reference to the terms “private international law” and “conflict of laws” interchangeably, although “conflict of laws” will be preferred for reasons of taste rather than logic. The aim of this paper is to illustrate the concept of conflict of laws in general and how it significantly impacts the manner in which courts will ultimately decide on the law to be applied in a matter possibly involving inter alia international diamond transactions. This demonstrates the consistent relevance of conflict of laws particularly in light of the global economy. The correct identification and understanding of conflict of laws’ principles can be stretched to accommodate all other areas of international trade. However, for the purposes of understanding how diamond trade is impacted by conflict of laws in South Africa, this paper will be limited to the legal context of diamond-relevant trade and the latest guidelines provided by our courts in relation to the choice of law in matters where conflict of laws has arisen.
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- 2021
8. Pedagogies and Strategies in International Maritime Business
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Fikile Portia Ndlovu
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Work (electrical) ,business.industry ,Excellence ,media_common.quotation_subject ,Political science ,Economic shortage ,Engineering ethics ,Training and development ,Human resources ,business ,Training (civil) ,GeneralLiterature_MISCELLANEOUS ,media_common - Abstract
Until we find an equally or more efficient way to get 90% of everything we need from markets around the world, the maritime world must make a conscious effort to continue to support excellence in maritime pedagogy. This must be done through understanding the strategies that inform such a specialized area of maritime work. It is a fact that modern maritime pedagogy brings in many new strategies, but these will be more effective if the lens of maritime pedagogical history and challenges are understood. It is the aim of this paper to highlight teaching and learning strategies in international maritime business in light of the latest developments and to highlight areas where the maritime pedagogy can best support human resource training and development in the maritime world. Maritime training must anticipate the needs of the industry in time rather than waiting until there are skills shortages.
- Published
- 2020
9. Ballast Water Management and Environmental Protection
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Fikile Portia Ndlovu, Editor and Fikile Portia Ndlovu, Editor
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- Discharge of ballast water--Environmental aspects, Ballast water--Management, Environmental protection, Ballast water--Purification
- Abstract
This book addresses the extensive global efforts of the International Maritime Organization to create rules around effective ballast water management. It will appeal to the marine environmental administrator, technology developer, port authority, shipowner, maritime lawyer, researcher, educator and student in the area of aquatic invasive species. The book highlights the technical and technological steps that an organization may take to achieve the now-established global standard for preventing ships from introducing marine invasive species through the ship's ballast water. In addition to highlighting technologies to prevent invasions, it calls for more active efforts to deal with already existing dangerous invasions. The book covers aspects of, among others, ballast water management regulation, enforcement, shipowner responsibilities, an industry attitude survey on this issue, risk management, cyber security, and addressing ballast water management in the Arctic.
- Published
- 2022
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