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136 results on '"Peluso, Antonio"'

1. Which inflammatory marker, between systemic immune-inflammation index and neutrophil to eosinophil ratio, is associated with Peyronie’s disease and are there any implications for a better understanding of its mechanisms?

Author

Crocetto, Felice, Imbimbo, Ciro, Barone, Biagio, Turchino, Davide, Bracale, Umberto Marcello, Peluso, Antonio, Panagrosso, Marco, Falcone, Alfonso, Mirto, Benito Fabio, De Luca, Luigi, Sicignano, Enrico, Del Giudice, Francesco, Busetto, Gian Maria, Lucarelli, Giuseppe, Giampaglia, Gaetano, Manfredi, Celeste, Ferro, Matteo, and Tarantino, Giovanni

Published
2023
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8. Are very short necks ESAR patients safe from type 1A endoleak risk?

Author

ACCARINO, Giulio, primary, PELUSO, Antonio, additional, TURCHINO, Davide, additional, FORNINO, Giovanni, additional, PUCA, Aniello E., additional, DE ROSA, Carmela, additional, ACCARINO, Giancarlo, additional, GALASSO, Gennaro, additional, SERRA, Raffaele, additional, and BRACALE, Umberto M., additional

Published
2024
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14. PS-BPB04-6: PROOF OF BIOLOGICAL ACTIVITY AND EXPLORATION OF EARLY SIGNALING EVENTS OF ANGIOTENSIN-(1–5)

Author

Silva, Igor Maciel Souza, primary, Peluso, Antonio Augusto, additional, Jakobsen, Lene Andrup, additional, Jensen, Pia, additional, Ribeiro, Lucas Rodrigues Aguiar, additional, Mortensen, Christina, additional, Sumners, Colin, additional, Braga, Thiago Verano, additional, Larsen, Martin Roessel, additional, and Steckelings, Ulrike Muscha, additional

Published
2023
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22. Position Paper on Young Vascular Surgeons Training of the Mediterranean Federation for the Advancing of Vascular Surgery (MeFAVS): State of the Art and Perspectives

Author

Bracale, Umberto Marcello, Ammollo, Raffaele Pio, Hussein, Emad A., Hoballah, Jamal J., Taurino, Maurizio, Saleem, Ben R., Setacci, Carlo, Pecoraro, Felice, Serra, Raffaele, Bracale, Giancarlo, Panagrosso, Marco, Peluso, Antonio, Petrone, Anna, Maisto, Marianna, del Guercio, Luca, Dinoto, Ettore, Bajardi, Guido, Bouayed, Mohamed N., Zeebregts, Clark J., Pulli, Raffaele, Pane, Bianca, Pratesi, Giovanni, Castelli, Patrizio, Setacci, Francesco, Gargiulo, Mauro, Stella, Andrea, Illario, Maddalena, De Luca, Vincenzo, Verhoeven, Eric L.G., Riambau, Vincent, Saratzis, Nikolaos, Cvjetko, Ivan, Resch, Timothy, Fernandes e Fernandes, José, Chiche, Laurent, and Goeau-Brissonniere, Olivier

Published
2021
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24. Next Generation Diabetes Scientists Shape Global Research Culture:A reflective proposal from postdoctoral researchers in diabetes research

Author

Gonzalez-Franquesa, Alba, Carrasquilla Lopez, German Dario, Mamidi, Anant, Ghiasi, Seyed Mojtaba, Juel, Helene Bæk, Falk, Sarah, Isidor, Marie Sophie, Gillberg, Linn Maria Ellinor, Huang, Lam Opal, Quist, Jonas Salling, Knudsen, Jonas Roland, Quaranta, Roberto, Tozzi, Marco, Mikkelsen, Randi Bonke, Dall, Morten, Drag, Markus Hodal, Small, Lewin Barkla, Altıntaş, Ali, Osborne, Brenna, Modvig, Ida Marie, Husted, Anna Sofie, Brown, Erin Louise, Bak, Emilie Glad, Bastos Peluso, Antonio Augusto, Finger, Fabian Michael, Grunddal, Kaare Villum, Rupar, Kaja, Henningsen, Jo Beldring, Pedersen, Maria Hauge, Plucinska, Kaja, Gonzalez-Franquesa, Alba, Carrasquilla Lopez, German Dario, Mamidi, Anant, Ghiasi, Seyed Mojtaba, Juel, Helene Bæk, Falk, Sarah, Isidor, Marie Sophie, Gillberg, Linn Maria Ellinor, Huang, Lam Opal, Quist, Jonas Salling, Knudsen, Jonas Roland, Quaranta, Roberto, Tozzi, Marco, Mikkelsen, Randi Bonke, Dall, Morten, Drag, Markus Hodal, Small, Lewin Barkla, Altıntaş, Ali, Osborne, Brenna, Modvig, Ida Marie, Husted, Anna Sofie, Brown, Erin Louise, Bak, Emilie Glad, Bastos Peluso, Antonio Augusto, Finger, Fabian Michael, Grunddal, Kaare Villum, Rupar, Kaja, Henningsen, Jo Beldring, Pedersen, Maria Hauge, and Plucinska, Kaja

Abstract

The annual Winter School of the Danish Diabetes Academy (DDA) in November 2019 challenged postdoctoral researchers with tough questions regarding research culture that scientists around the world are discussing. The complexity and competitiveness of modern research makes it increasingly difficult for junior researchers to navigate in the science community. This editorial reflects the voices of nearly 200 international researchers ranging from early-career scientists to professors and medical doctors discussing five challenges of modern research culture - and proposes innovative solutions to overcome them.

Published
2020

34. Adsorbent for halogenated anaesthetics

Author

Mladen, Eic, Filipovic, Dusanka, Hua, Ye, APREA, PAOLO, CAPUTO, DOMENICO, GARGIULO, NICOLA, PELUSO, ANTONIO, Mladen, Eic, Filipovic, Dusanka, Aprea, Paolo, Caputo, Domenico, Gargiulo, Nicola, Hua, Ye, and Peluso, Antonio

Abstract

An adsorbent for halogenated anaesthetics includes: an inorganic material; and an organic material providing a framework for the inorganic material. The inorganic material may be chromium and the organic material may be terephthalic acid. The adsorbent may be formed or configured such that the adsorbent includes coordinatively unsaturated sites or such that the inorganic material may form octahedral structures. The adsorbent is formed or configured to be substantially regenerated at approximately room temperature and to provide selectivity for sevofluorane in water vapour of approximately 1.0. A method of producing an adsorbent includes: selecting an appropriate chemical containing an inorganic material; selecting an organic material to provide a framework for the inorganic material; dissolving the base chemical in water; mixing the organic material with the dissolved base chemical; heating the mixture; filtering the mixture to remove excess organic material; and drying the filtrate.

Published
2016

36. The acute blood pressure-lowering effect of amiloride is independent of endothelial ENaC and eNOS in humans and mice

Author

Ydegaard, Rikke, primary, Andersen, Henrik, additional, Oxlund, Christina S., additional, Jacobsen, Ib A., additional, Hansen, Pernille B. L., additional, Jürgensen, Jonathan F., additional, Peluso, Antonio Augusto, additional, Vanhoutte, Paul M., additional, Staehr, Mette, additional, Svenningsen, Per, additional, and Jensen, Boye L., additional

Published
2018
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37. A16523 Mapping of the angiotensin AT2 receptor-coupled signalling network by time-resolved quantitative phosphoproteomics in human aortic endothelial cells identified HDAC-1 and p53 to be involved in AT2 receptor-mediated anti-proliferation

Author

Steckelings, Ulrike Muscha, primary, Peluso, Antonio Augusto Bastos, additional, Kempf, Stefan J., additional, Brega, Thiago Verano, additional, Bader, Michael, additional, Larsen, Martin R., additional, and Santos, Robson A.S., additional

Published
2018
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42. Nanoporous Materials as H2S Adsorbents for Biogas Purification: a Review.

Author

Peluso, Antonio, Gargiulo, Nicola, Aprea, Paolo, Pepe, Francesco, and Caputo, Domenico

Subjects
*NANOPOROUS materials, *BIOGAS, *CHEMICAL purification, *RENEWABLE energy sources, *ENERGY conversion, *MESOPOROUS silica
Abstract

Biogas is one of the most promising renewable sources of energy. However, it is also a gas mixture containing acidic gases, such as H2S, useless for energetic purposes, environmentally harmful and damaging for energy conversion devices. This review focuses on nanoporous materials as adsorbents of H2S for biogas purification processes. Cation-exchanged zeolites and impregnated activated carbons have been thoroughly studied since many years for this application, providing good results, in particular for what concerns activated carbons, despite having a limited regenerability. Amino-functionalized ordered mesoporous silicas produced very interesting results, both in terms of adsorption performances and regeneration capacity, but they are largely untested in large-scale “real-life” applications, and deserve further investigations, in particular for H2S and CO2 discrimination. On the contrary, despite reporting very good results, there are only few papers dealing with H2S adsorption on nanoporous metal organic frameworks. [ABSTRACT FROM AUTHOR]

Published
2019
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44. Collagen-Based Vascular Closure Device Multicenter Italian Experience in Endovascular Aortic Aneurysm Repair Compared With Suture-Mediated Closure Vascular Device

Author

Panagrosso, Marco, Cavallo, Eduardo, Bracale, Umberto Marcello, Peluso, Antonio, Silvestri, Olga, Intrieri, Francesco, Molinari, Vincenzo, Esposito, Antonio, Trimarchi, Santi, Settembrini, Alberto Maria, Lomazzi, Chiara, La Barbera, Gaetano, Carbonari, Luciano, Angelini, Andrea, Morelli, Irene, Centonza, Eleonora, Berchiolli, Raffaella, Troisi, Nicola, Scarati, Valentina, Artini, Valerio, De Vivo, Salvatore, Volpe, Pietro, Massara, Mafalda, and Martelli, Eugenio

Abstract

Purpose: The Manta Vascular Closure Device is a novel collagen-based vascular closure device that has been designed specifically for closure of large-bore percutaneous arterial accesses. The aim of this retrospective study is to evaluate the immediate and 30-day outcome of Manta at the completion of endovascular aneurysm repair (EVAR) or thoracic endovascular aortic repair (TEVAR). The hypothesis is that Manta is not inferior in obtaining hemostasis compared with the Perclose ProGlide Suture-Mediated Closure System device.Materials and Methods: We recruited all the percutaneous accesses for (T)EVAR performed from January 2021 to April 2023 by all the Italian Divisions of Vascular Surgery using Manta at the time of data collection (May 2023). The primary outcome is to evaluate the incidence of complications at the puncture site after Manta implantation and at 1 month, and compare this with ProGlide. We applied the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) criteria for observational studies.Results: Overall, 524 consecutive femoral accesses for (T)EVAR procedures were collected: 355 in the Manta cohort and 169 in the ProGlide cohort, respectively. The size of the sheath was 17.2±2.7 Fr for Manta, 15.7±2.3 Fr for ProGlide (p<0.001). No statistically significant differences between the groups regarding age, sex, body mass index, ultrasound-guided access, femoral calcifications, intraoperative, and 30-day complications. Successful arterial closure at groin puncture sites for (T)EVAR using Manta is 90.5% and 93.1% using ProGlide. Freedom for any reintervention for any complication is 95.5% for Manta and 96% for ProGlide.Conclusion: The 2 vascular closure devices have proved to be similar in terms of complications, without any statistically significant difference, although the median size of the sheaths for (T)EVAR was statistically significantly larger when Manta has been used, compared with ProGlide.Clinical Impact Manta® is effective in the hemostasis of the access sites following the completion of (T)EVAR in this multicenter, retrospective, case-control study on 524 percutaneous femoral accesses. Compared to the more popular Proglide®, the average size of the introducers in the Manta® group was significantly larger than in the Proglide® group.

Published
2024
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48. Carotid Endarterectomy versus Carotid Artery Stenting With Double-Layer Micromesh Carotid Stent: Contemporary Results of a Single-Center Retrospective Study

Author

Bracale, Umberto Marcello, Peluso, Antonio, Mauro, Ernesto Di, Guercio, Luca del, Taranto, Maria Donata Di, Giannotta, Nicola, Ielapi, Nicola, Provenzano, Michele, Andreucci, Michele, and Serra, Raffaele

Abstract

Severe carotid stenosis (CS) is a major risk factor for stroke. Carotid Endarterectomy (CEA) is the gold standard revascularization technique of CS while carotid artery stenting (CAS) is considered an alternative treatment option, especially in high-risk patients or those with relative contraindications to CEA. The aim of this study was to evaluate the results of CEA and CAS with Roadsaver® stent device.

Published
2021
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49. Anti‐fibrotic mechanisms of angiotensin AT2‐receptor stimulation.

Author

Sumners, Colin, Peluso, Antonio Augusto, Haugaard, Andreas Houe, Bertelsen, Jesper Bork, and Steckelings, Ulrike Muscha

Subjects
*DRUG receptors, *NEPRILYSIN, *G protein coupled receptors, *RENIN-angiotensin system, *MYOFIBROBLASTS, *FIBROSIS, *ANIMAL disease models, *CLINICAL indications
Abstract

The angiotensin AT2‐receptor is a main receptor of the protective arm of the renin‐angiotensin system. Understanding of this unconventional G‐protein coupled receptor has significantly advanced during the past decade, largely because of the availability of a selective non‐peptide AT2‐receptor agonist, which allowed the conduct of a multitude of studies in animal disease models. This article reviews such preclinical studies that in their entirety provide strong evidence for an anti‐fibrotic effect mediated by activation of the AT2‐receptor. Prevention of the development of fibrosis by AT2‐receptor stimulation has been demonstrated in lungs, heart, blood vessels, kidney, pancreas and skin. In lungs, AT2‐receptor stimulation was even able to reverse existing fibrosis. The article further discusses intracellular signalling mechanisms mediating the AT2‐receptor‐coupled anti‐fibrotic effect, including activation of phosphatases and subsequent interference with pro‐fibrotic signalling pathways, induction of matrix‐metalloproteinases and hetero‐dimerization with the AT1‐receptor, the TGF‐βRII‐receptor or the RXFP1‐receptor for relaxin. Knowledge of the anti‐fibrotic effects of the AT2‐receptor is of particular relevance because drugs targeting this receptor have entered clinical development for indications involving fibrotic diseases. [ABSTRACT FROM AUTHOR]

Published
2019
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50. The acute blood pressure‐lowering effect of amiloride is independent of endothelial ENaC and eNOS in humans and mice.

Author

Ydegaard, Rikke, Andersen, Henrik, Oxlund, Christina S., Jacobsen, Ib A., Hansen, Pernille B. L., Jürgensen, Jonathan F., Peluso, Antonio Augusto, Vanhoutte, Paul M., Stæhr, Mette, Svenningsen, Per, and Jensen, Boye L.

Subjects
AMILORIDE, ARTERIAL pressure, SODIUM channels, ENDOTHELIAL cells, NITRIC-oxide synthases, SODIUM channel blockers, BENZAMIL
Abstract

Aims: The epithelial sodium channel (ENaC) is expressed in cultured endothelial cells and inhibitory coupling to eNOS activity has been proposed. The present study tested the hypothesis that ENaC blockers increase systemic NO‐products and lower blood pressure in patients and mice, depending on eNOS. Methods: NO‐products and cGMP were measured in diabetes patient urine and plasma samples before and after amiloride treatment (20‐40 mg for two days, plasma n = 22, urine n = 12 and 5‐10 mg for eight weeks, plasma n = 52, urine n = 55). Indwelling catheters were implanted in the femoral artery and vein in mice for continuous arterial blood pressure and heart rate recordings and infusion. Results: Treatment with amiloride for two days increased plasma and urine NO‐products, while plasma cGMP decreased and urinary cGMP was unchanged in patient samples. Eight weeks of treatment with amiloride did not alter NO‐products and cGMP. In mice, amiloride boli of 5, 50, and 500 µg/kg lowered heart rate and arterial blood pressure significantly and acutely. Benzamil had no effect on pressure and raised heart rate. In hypertensive eNOS−/− and L‐NAME‐treated mice, amiloride lowered blood pressure significantly. L‐NAME infusion significantly decreased NO‐products in plasma; amiloride and eNOS‐deletion had no effect. An acetylcholine bolus resulted in acute blood pressure drop that was attenuated in eNOS−/− and L‐NAME mice. ENaC subunit expressions were not detected consistently in human and mouse arteries and endothelial cells. Conclusion: Amiloride has an acute hypotensive action not dependent on ENaC and eNOS and likely related to the heart. [ABSTRACT FROM AUTHOR]

Published
2019
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