345 results on '"Patterson, Adam"'
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2. Valuation Versus Pricing: A Conceptual and Practical Guide to Estimate Economic Value for Early-Stage Companies Via DCF
3. Introduction to Startup Valuation: From Idea to IPO
4. Implementing an Acute Text-Based Wellness Alert System for Pediatric Residents: A Pilot Study
5. Epistemic Slurs: A Novel Explicandum and Adequacy Constraint for Slur Theories
6. Bioreductive prodrug PR-104 improves the tumour distribution and titre of the nitroreductase-armed oncolytic adenovirus ONYX-411NTR leading to therapeutic benefit
7. Use of an optimised enzyme/prodrug combination for Clostridia directed enzyme prodrug therapy induces a significant growth delay in necrotic tumours
8. Are Tech Savvy Students Tech Literate? Digital and Data Literacy Skills of First-Year College Students.
9. Structural Evaluation of a Nitroreductase Engineered for Improved Activation of the 5-Nitroimidazole PET Probe SN33623.
10. Exploration of anomalous perceptual experiences in migraine between attacks using the Cardiff Anomalous Perceptions Scale
11. Directed evolution of the B. subtilis nitroreductase YfkO improves activation of the PET-capable probe SN33623 and CB1954 prodrug
12. Getting all emotional about the fear of death 1
13. Synthesis and antiproliferative activity of culicinin D analogues containing simplified AHMOD-based residues
14. An industrial perspective on co-crystals: Screening, identification and development of the less utilised solid form in drug discovery and development
15. Hypoxia-activated prodrugs and (lack of) clinical progress: The need for hypoxia-based biomarker patient selection in phase III clinical trials
16. Discovery of 6‑Formylpyridyl Urea Derivatives as Potent Reversible-Covalent Fibroblast Growth Factor Receptor 4 Inhibitors with Improved Anti-Hepatocellular Carcinoma Activity.
17. Structural Mechanism and Inhibitors Targeting EGFR Exon 20 Insertion (Ex20ins) Mutations
18. Discovery and optimization of 1-(1H-indol-1-yl)ethanone derivatives as CBP/EP300 bromodomain inhibitors for the treatment of castration-resistant prostate cancer
19. Beyond Residents-as-Teachers: The Development of an Advanced Medical Education Pilot Elective for Pediatric Residents
20. 2-Oxo-3, 4-dihydropyrimido[4, 5-d]pyrimidinyl derivatives as new irreversible pan fibroblast growth factor receptor (FGFR) inhibitors
21. Engineering a Multifunctional Nitroreductase for Improved Activation of Prodrugs and PET Probes for Cancer Gene Therapy
22. Design and Biological Evaluation of Piperazine-Bearing Nitrobenzamide Hypoxia/GDEPT Prodrugs: The Discovery of CP-506.
23. Genetic Engineering of Clostridial Strains for Cancer Therapy
24. Data from Molecular and Cellular Pharmacology of the Hypoxia-Activated Prodrug TH-302
25. Supplementary Methods, Tables 1-5, Figures 1-9 from Molecular and Cellular Pharmacology of the Hypoxia-Activated Prodrug TH-302
26. Supplementary Data from Nitro-chloromethylbenzindolines: hypoxia-activated prodrugs of potent adenine N3 DNA minor groove alkylators
27. Supplementary Figure S3 from Tarloxotinib Is a Hypoxia-Activated Pan-HER Kinase Inhibitor Active Against a Broad Range of HER-Family Oncogenes
28. Supplementary Table 1 from Tarloxotinib Is a Hypoxia-Activated Pan-HER Kinase Inhibitor Active Against a Broad Range of HER-Family Oncogenes
29. Data from Roles of DNA repair and reductase activity in the cytotoxicity of the hypoxia-activated dinitrobenzamide mustard PR-104A
30. Supplementary Table S2 from Tarloxotinib Is a Hypoxia-Activated Pan-HER Kinase Inhibitor Active Against a Broad Range of HER-Family Oncogenes
31. Supplementary Data from Roles of DNA repair and reductase activity in the cytotoxicity of the hypoxia-activated dinitrobenzamide mustard PR-104A
32. Data from Optimized Clostridium-Directed Enzyme Prodrug Therapy Improves the Antitumor Activity of the Novel DNA Cross-Linking Agent PR-104
33. Data from The Bioreductive Prodrug PR-104A Is Activated under Aerobic Conditions by Human Aldo-Keto Reductase 1C3
34. Data from DNA Cross-Links in Human Tumor Cells Exposed to the Prodrug PR-104A: Relationships to Hypoxia, Bioreductive Metabolism, and Cytotoxicity
35. Supplementary Figure 1 from DNA Cross-Links in Human Tumor Cells Exposed to the Prodrug PR-104A: Relationships to Hypoxia, Bioreductive Metabolism, and Cytotoxicity
36. Supplementary Figure 2 from DNA Cross-Links in Human Tumor Cells Exposed to the Prodrug PR-104A: Relationships to Hypoxia, Bioreductive Metabolism, and Cytotoxicity
37. Supplementary Figure 4 from DNA Cross-Links in Human Tumor Cells Exposed to the Prodrug PR-104A: Relationships to Hypoxia, Bioreductive Metabolism, and Cytotoxicity
38. Supplementary Table 1 from DNA Cross-Links in Human Tumor Cells Exposed to the Prodrug PR-104A: Relationships to Hypoxia, Bioreductive Metabolism, and Cytotoxicity
39. Supplementary Figure 3 from DNA Cross-Links in Human Tumor Cells Exposed to the Prodrug PR-104A: Relationships to Hypoxia, Bioreductive Metabolism, and Cytotoxicity
40. Supplementary Materials, Tables 1-9, Figures 1-8 from The Bioreductive Prodrug PR-104A Is Activated under Aerobic Conditions by Human Aldo-Keto Reductase 1C3
41. Supplementary Table 1 from Optimized Clostridium-Directed Enzyme Prodrug Therapy Improves the Antitumor Activity of the Novel DNA Cross-Linking Agent PR-104
42. Building a System to Solve the Challenges of Drilling Hot Hard Rock for Geothermal and Oil and Gas
43. The determinants of complication trajectories in American Indians with type 2 diabetes
44. Agricultural Effects of Unconventional Oil and Gas Development: A Machine Learning Approach
45. Design, Synthesis, and Biological Evaluation of 5-Formyl-pyrrolo[3,2-b]pyridine-3-carboxamides as New Selective, Potent, and Reversible-Covalent FGFR4 Inhibitors
46. Discovery of Isoform-Selective Akt3 Degraders Overcoming Osimertinib-Induced Resistance in Non-Small Cell Lung Cancer Cells
47. Characterization of the cutaneous mycobiota in healthy and allergic cats using next generation sequencing
48. Dedication
49. Acknowledgments
50. Teaching Data Literacy and Sports Economic Fundamentals Using Fantasy Sports.
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