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Background: Pediatric regulations enacted in both Europe and the USA have disrupted the pharmaceutical industry, challenging business and drug development processes, and organizational structures. Over the last decade, with science and innovation evolving, industry has moved from a reactive to a proactive mode, investing in building appropriate structures and capabilities as part of their business strategy to better tackle the challenges and opportunities of pediatric drug development. Methods: The EFGCP Children's Medicines Working Party and the IQ Pediatric working group have joined their efforts to survey their member company representatives to understand how pharmaceutical companies are organized to fulfill their regulatory obligations and optimize their pediatric drug development programs. Results: Key success factors and recommendations for a fit-for-purpose Pediatric Expert Group (PEG) were identified. Conclusion: Pediatric structures and expert groups were shown to be important to support optimization of the development of pediatric medicines. [ABSTRACT FROM AUTHOR]

The article How is the Pharmaceutical Industry Structured to Optimize Pediatric Drug Development? Existing Pediatric Structure Models and Proposed Recommendations for Structural Enhancement, written by Thomas Severin et al. was originally published electronically on the publisher's internet portal on February 6, 2020 without open access. With the author(s)' decision to opt for Open Choice the copyright of the article changed on April 22, 2020 to © The Author(s) 2020 and the article is forthwith distributed under a Creative Commons Attribution 4.0 International License https://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. [ABSTRACT FROM AUTHOR]

The Editorial Board of Acta Paediatrica wishes to express its sincere gratitude to the following persons outside the Editorial Committee, who in a very constructive way have acted as referees during the past year. B A b çimen, Irem Damla Abo, Yara Abrahamsen, Tore Abu-Harb, Majd Abu-Shaweesh, Jalal Adams, Mark Addabbo, Margaret Adler, Frederick Aghai, Zubair Aguayo, Josefa Ahlfeld, Shawn Ahlqvist-Björkroth, Sari Ahlsson, Fredrik Alam, Nur Alfvén, Gösta Alfvén, Tobias Allegaert, Karel Alm, Bernt Almqvist, Kjerstin Altman, Maria Amadi, Hippolite Onyejiaka Anderlid, Britt-Marie Andersen, Randi Dovland Andersson, Ketty Andersson, Nadine Andersson, Ola Andersson, Roland Andersson, Sture Arnell, Henrik Aronsson, Bernice Arthur, Julia Asarnoj, Anna Atout, Maha Autio, Timo Awasthi, Shally Axberg, Ulf Axelsson, Inge B B b Backes, Carl Backman, Katri Bagolan, Pietro Baguley, Katherine Baker, Jennifer Ball, Helen Balla, Uri Bamat, Nicolas Bancalari, Eduardo Bandeira, Teresa Banerjee, Jayanta Bartocci, Marco Basal, Donald Baskin, Laurence Battelino, Tadej Beard, Lauren Beck, Michael Beckers, Thijs Bellieni, Carlo Bellini, Carlo Ben-Ari, Yéhézkel Bendabenda, Jaden Bennet, Rutger Bentur, Lea Benzies, Karen Berbyuk Lindström, Nataliya Berg, Lisa Berger, Angelika Bergfors, Elisabet Bergman, Patrick Bergounioux, Jean. [Extracted from the article]

The Editorial Board of Acta Paediatrica wishes to express its sincere gratitude to the following persons outside the Editorial Committee, who in a very constructive way have acted as referees during the past year. Hård, Anna-Lena Myléus, Anna Nilsson, Anna Nordenström, Anna. [Extracted from the article]