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106 results on '"Naylor, D. A."'

1. Modal Simulation Framework for the Design and Verification of Future Few-Mode Far-Infrared Spectrometers

Author

Lap, B. N. R., Jellema, W., Withington, S., and Naylor, D. A.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

Future far-infrared space missions require highly-sensitive spectroscopy as a primary diagnostics tool. However, these systems are sensitive to straylight, due to the ultra-sensitive few-mode detectors used, which affects the measurement and calibration of the spectrum, as revealed by the Herschel mission. To ensure that the science goals of future missions are met, the complex modal behaviour has to be understood, and appropriate verification and calibration strategies must be developed. We propose a modal framework to addresses these issues, using Herschel-SPIRE as a case study, and demonstrate how the technique can be used for the design and verification of spectrometers in future far-infrared missions., Comment: This pre-print was submitted to SPIE Astronomical Telescopes + Instrumentation 2022

Published
2022

2. Modelling the Partially Coherent Behaviour of Few-Mode Far-Infrared Grating Spectrometers

Author

Lap, B. N. R., Withington, S., Jellema, W., and Naylor, D. A.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

Modelling ultra-low-noise far-infrared grating spectrometers has become crucial for the next generation of far-infrared space observatories. Conventional techniques are awkward to apply because of the partially coherent form of the incident spectral field, and the few-mode response of the optics and detectors. We present a modal technique for modelling the behaviour of spectrometers, which allows for the propagation and detection of partially coherent fields, and the inclusion of straylight radiated by warm internal surfaces. We illustrate the technique by modelling the behaviour of the Long Wavelength Band of the proposed SAFARI instrument on the well-studied SPICA mission., Comment: This paper is submitted to Journal Optical Society of America A. When accepted, the paper can be found here: https://opg.optica.org/josaa/home.cfm

Published
2022
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4. The formation of planetary systems with SPICA

Author

Kamp, I., Honda, M., Nomura, H., Audard, M., Fedele, D., Waters, L. B. F. M., Aikawa, Y., Banzatti, A., Bowey, J. E., Bradford, M., Dominik, C., Furuya, K., Habart, E., Ishihara, D., Johnstone, D., Kennedy, G., Kim, M., Kral, Q., Lai, S. P., Larsson, B., McClure, M., Miotello, A., Momose, M., Nakagawa, T., Naylor, D., Nisini, B., Notsu, S., Onaka, T., Pantin, E., Podio, L., Marichalar, P. Riviere, Rocha, W. R. M., Roelfsema, P., Santos, F., Shimonishi, T., Tang, Y. W., Takami, M., Tazaki, R., Wolf, S., Wyatt, M., and Ysard, N.

Subjects
Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

In this era of spatially resolved observations of planet forming disks with ALMA and large ground-based telescopes such as the VLT, Keck and Subaru, we still lack statistically relevant information on the quantity and composition of the material that is building the planets, such as the total disk gas mass, the ice content of dust, and the state of water in planetesimals. SPICA is an infrared space mission concept developed jointly by JAXA and ESA to address these questions. The key unique capabilities of SPICA that enable this research are (1) the wide spectral coverage 10-220 micron, (2) the high line detection sensitivity of (1-2) 10-19 W m-2 with R~2000-5000 in the far-IR (SAFARI) and 10-20 W m-2 with R~29000 in the mid-IR (SMI, spectrally resolving line profiles), (3) the high far-IR continuum sensitivity of 0.45 mJy (SAFARI), and (4) the observing efficiency for point source surveys. This paper details how mid- to far-IR infrared spectra will be unique in measuring the gas masses and water/ice content of disks and how these quantities evolve during the planet forming period. These observations will clarify the crucial transition when disks exhaust their primordial gas and further planet formation requires secondary gas produced from planetesimals. The high spectral resolution mid-IR is also unique for determining the location of the snowline dividing the rocky and icy mass reservoirs within the disk and how the divide evolves during the build-up of planetary systems. Infrared spectroscopy (mid- to far-IR) of key solid state bands is crucial for assessing whether extensive radial mixing, which is part of our Solar System history, is a general process occurring in most planetary systems and whether extrasolar planetesimals are similar to our Solar System comets/asteroids. ... (abbreviated), Comment: accepted for publication in PASA

Published
2021
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5. The Herschel SPIRE Fourier Transform Spectrometer Spectral Feature Finder I. The Spectral Feature Finder and Catalogue

Author

Hopwood, R., Valtchanov, I., Spencer, Locke D., Scott, J. P., Benson, C. S., Marchili, N., Hladczuk, N., Polehampton, E. T., Lu, N., Makiwa, G., Naylor, D. A., Gom, B. G., Noble, G., and Griffin, M. J.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Astrophysics of Galaxies
Abstract

We provide a detailed description of the Herschel-SPIRE Fourier Transform Spectrometer (FTS) Spectral Feature Finder (FF). The FF is an automated process designed to extract significant spectral features from SPIRE FTS data products. Optimising the number of features found in SPIRE-FTS spectra is challenging. The wide SPIRE-FTS frequency range (447-1568 GHz) leads to many molecular species and atomic fine structure lines falling within the observed bands. As the best spectral resolution of the SPIRE-FTS is ~1.2 GHz, there can be significant line blending, depending on the source type. In order to find, both efficiently and reliably, features in spectra associated with a wide range of sources, the FF iteratively searches for peaks over a number of signal-to-noise ratio (SNR) thresholds. For each threshold, newly identified features are rigorously checked before being added to the fitting model. At the end of each iteration, the FF simultaneously fits the continuum and features found, with the resulting residual spectrum used in the next iteration. The final FF products report the frequency of the features found and the associated SNRs. Line flux determination is not included as part of the FF products, as extracting reliable line flux from SPIRE-FTS data is a complex process that requires careful evaluation and analysis of the spectra on a case-by-case basis. The FF results are 100% complete for features with SNR greater than 10 and 50-70% complete at SNR of 5. The FF code and all FF products are publicly available via the Herschel Science Archive., Comment: 20 pages, 8 figures, 8 tables, final version accepted by MNRAS June 2020

Published
2020
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6. Far-infrared Herschel SPIRE spectroscopy of lensed starbursts reveals physical conditions of ionised gas

Author

Zhang, Zhi-Yu, Ivison, R. J., George, R. D., Zhao, Yinghe, Dunne, L., Herrera-Camus, R., Lewis, A. J. R., Liu, Daizhong, Naylor, D., Oteo, Ivan, Riechers, D. A., Smail, Ian, Yang, Chentao, Eales, Stephen, Hopwood, Ros, Maddox, Steve, Omont, Alain, and van der Werf, Paul

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

The most intensively star-forming galaxies are extremely luminous at far-infrared (FIR) wavelengths, highly obscured at optical and ultraviolet wavelengths, and lie at $z\ge 1-3$. We present a programme of ${\it Herschel}$ FIR spectroscopic observations with the SPIRE FTS and photometric observations with PACS, both on board ${\it Herschel}$, towards a sample of 45 gravitationally lensed, dusty starbursts across $z\sim 1-3.6$. In total, we detected 27 individual lines down to 3-$\sigma$, including nine $[\rm C{\small II}]$ 158-$\mu$m lines with confirmed spectroscopic redshifts, five possible $[\rm C{\small II}]$ lines consistent with their far-infrared photometric redshifts, and in some individual sources a few $[\rm O{\small III}]$ 88-$\mu$m, $[\rm O{\small III}]$ 52-$\mu$m, $[\rm O{\small I}]$ 145-$\mu$m, $[\rm O{\small I}]$ 63-$\mu$m, $[\rm N{\small II}]$ 122-$\mu$m, and OH 119-$\mu$m (in absorption) lines. To derive the typical physical properties of the gas in the sample, we stack all spectra weighted by their intrinsic luminosity and by their 500-$\mu$m flux densities, with the spectra scaled to a common redshift. In the stacked spectra, we detect emission lines of $[\rm C{\small II}]$ 158-$\mu$m, $[\rm N{\small II}]$ 122-$\mu$m, $[\rm O{\small III}]$ 88-$\mu$m, $[\rm O{\small III}]$ 52-$\mu$m, $[\rm O{\small I}]$ 63-$\mu$m, and the absorption doublet of OH at 119-$\mu$m, at high fidelity. We find that the average electron densities traced by the $[\rm N{\small II}]$ and $[\rm O{\small III}]$ lines are higher than the average values in local star-forming galaxies and ULIRGs, using the same tracers. From the $[\rm N{\small II}]/[\rm C{\small II}]$ and $[\rm O{\small I}]/[\rm C{\small II}]$ ratios, we find that the $[\rm C{\small II}]$ emission is likely dominated by the photo-dominated regions (PDR), instead of by ionised gas or large-scale shocks., Comment: 39 pages, 19 figures, Accepted for publication in MNRAS. For extra pptx slides prepared for this work, please see http://www.eso.org/~zzhang/download/FTS_SMG_survey_ZhiyuZhang.pdf

Published
2018
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7. SPICA - a large cryogenic infrared space telescope Unveiling the obscured Universe

Author

Roelfsema, P. R., Shibai, H., Armus, L., Arrazola, D., Audard, M., Audley, M. D., Bradford, C. M., Charles, I., Dieleman, P., Doi, Y., Duband, L., Eggens, M., Evers, J., Funaki, I., Gao, J. R., Giard, M., Fernández, A. di Giorgio L. M. González, Griffin, M., Helmich, F. P., Hijmering, R., Huisman, R., Ishihara, D., Isobe, N., Jackson, B., Jacobs, H., Jellema, W., Kamp, I., Kaneda, H., Kawada, M., Kemper, F., Kerschbaum, F., Khosropanah, P., Kohno, K., Kooijman, P. P., Krause, O., van der Kuur, J., Kwon, J., Laauwen, W. M., de Lange, G., Larsson, B., van Loon, D., Madden, S. C., Matsuhara, H., Najarro, F., Nakagawa, T., Naylor, D., Ogawa, H., Onaka, T., Oyabu, S., Poglitsch, A., Reveret, V., Rodriguez, L., Spinoglio, L., Sakon, I., Sato, Y., Shinozaki, K., Shipman, R., Sugita, H., Suzuki, T., van der Tak, F. F. S., Redondo, J. Torres, Wada, T., Wang, S. Y., Wafelbakker, C. K., van Weers, H., Withington, S., Vandenbussche, B., Yamada, T., and Yamamura, I.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

Measurements in the infrared wavelength domain allow us to assess directly the physical state and energy balance of cool matter in space, thus enabling the detailed study of the various processes that govern the formation and early evolution of stars and planetary systems in galaxies over cosmic time. Previous infrared missions, from IRAS to Herschel, have revealed a great deal about the obscured Universe, but sensitivity has been limited because up to now it has not been possible to fly a telescope that is both large and cold. SPICA is a mission concept aimed at taking the next step in mid- and far-infrared observational capability by combining a large and cold telescope with instruments employing state-of-the-art ultra-sensitive detectors. The mission concept foresees a 2.5-meter diameter telescope cooled to below 8 K. With cooling provided by mechanical coolers instead of depending on a limited cryogen supply, the mission lifetime can extend significantly beyond the required three years. SPICA offers instrumentation with spectral resolving powers ranging from R ~50 through 11000 in the 17-230 $\mu$m domain as well as R~28.000 spectroscopy between 12 and 18 $\mu$m. Additionally SPICA will provide efficient 30-37 $\mu$m broad band mapping, and polarimetric imaging in the 100-350 $\mu$m range. SPICA will provide unprecedented spectroscopic sensitivity of ~5 x $10^{-20}$ W/m$^2$ (5$\sigma$/1hr) - at least two orders of magnitude improvement over what has been attained to date. With this exceptional leap in performance, new domains in infrared astronomy will become accessible, allowing us, for example, to unravel definitively galaxy evolution and metal production over cosmic time, to study dust formation and evolution from very early epochs onwards, and to trace the formation history of planetary systems., Comment: 34 pages, 22 figures, paper accepted for publication in PASA on 2nd February 2018, part of the PASA SPICA Special Issue

Published
2018
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8. Correcting the extended-source calibration for the Herschel-SPIRE Fourier-Transform Spectrometer

Author

Valtchanov, Ivan, Hopwood, R., Bendo, G., Benson, C., Conversi, L., Fulton, T., Griffin, M. J., Joubaud, T., Lim, T., Lu, N., Marchili, N., Makiwa, G., Meyer, R. A., Naylor, D. A., North, C., Papageorgiou, A., Pearson, C., Polehampton, E. T., Scott, J., Schulz, B., Spencer, L. D., van der Wiel, M. H. D., and Wu, R.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

We describe an update to the Herschel-SPIRE Fourier-Transform Spectrometer (FTS) calibration for extended sources, which incorporates a correction for the frequency-dependent far-field feedhorn efficiency, $\eta_\mathrm{FF}$. This significant correction affects all FTS extended-source calibrated spectra in sparse or mapping mode, regardless of the spectral resolution. Line fluxes and continuum levels are underestimated by factors of 1.3-2 in the Spectrometer Long-Wavelength band (SLW, 447-1018 GHz; 671-294 $\mu$m) and 1.4-1.5 in the Spectrometer Short-Wavelength band (SSW, 944-1568 GHz; 318-191 $\mu$m). The correction was implemented in the FTS pipeline version 14.1 and has also been described in the SPIRE Handbook since Feb 2017. Studies based on extended-source calibrated spectra produced prior to this pipeline version should be critically reconsidered using the current products available in the Herschel Science Archive. Once the extended-source calibrated spectra are corrected for $\eta_\mathrm{FF}$, the synthetic photometry and the broadband intensities from SPIRE photometer maps agree within 2-4% -- similar levels to the comparison of point-source calibrated spectra and photometry from point-source calibrated maps. The two calibration schemes for the FTS are now self-consistent: the conversion between the corrected extended-source and point-source calibrated spectra can be achieved with the beam solid angle and a gain correction that accounts for the diffraction loss., Comment: 9 pages, 6 figures, 1 table, MNRAS in press

Published
2017
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9. Calibration of Herschel SPIRE FTS observations at different spectral resolutions

Author

Marchili, N., Hopwood, R., Fulton, T., Polehampton, E. T., Valtchanov, I., Zaretski, J., Naylor, D. A., Griffin, M. J., Imhof, P., Lim, T., Lu, N., Makiwa, G., Pearson, C., and Spencer, L.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

The SPIRE Fourier Transform Spectrometer on board the Herschel Space Observatory had two standard spectral resolution modes for science observations: high resolution (HR) and low resolution (LR), which could also be performed in sequence (H+LR). A comparison of the HR and LR resolution spectra taken in this sequential mode, revealed a systematic discrepancy in the continuum level. Analysing the data at different stages during standard pipeline processing, demonstrates the telescope and instrument emission affect HR and H+LR observations in a systematically different way. The origin of this difference is found to lie in the variation of both the telescope and instrument response functions, while it is triggered by fast variation of the instrument temperatures. As it is not possible to trace the evolution of the response functions through auxiliary housekeeping parameters, the calibration cannot be corrected analytically. Therefore an empirical correction for LR spectra has been developed, which removes the systematic noise introduced by the variation of the response functions., Comment: 13 pages, 17 figures, 4 tables. Accepted for publication in MNRAS

Published
2016
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10. Three-dimensional distribution of hydrogen fluoride gas toward NGC6334 I and I(N)

Author

van der Wiel, M. H. D., Naylor, D. A., Makiwa, G., Satta, M., and Abergel, A.

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

Aims. We investigate the spatial distribution of a collection of absorbing gas clouds, some associated with the dense, massive star-forming core NGC6334 I, and others with diffuse foreground clouds. For the former category, we aim to study the dynamical properties of the clouds in order to assess their potential to feed the accreting protostellar cores. Methods. We use spectral imaging from the Herschel SPIRE iFTS to construct a map of HF absorption at 243 micron in a 6x3.5 arcmin region surrounding NGC6334 I and I(N). Results. The combination of new, spatially fully sampled, but spectrally unresolved mapping with a previous, single-pointing, spectrally resolved HF signature yields a 3D picture of absorbing gas clouds in the direction of NGC6334. Toward core I, the HF equivalent width matches that of the spectrally resolved observation. The distribution of HF absorption is consistent with three of the seven components being associated with this dense star-forming envelope. For two of the remaining four components, our data suggest that these clouds are spatially associated with the larger scale filamentary star-forming complex. Our data also implies a lack of gas phase HF in the envelope of core I(N). Using a simple description of adsorption onto and desorption from dust grain surfaces, we show that the overall lower temperature of the envelope of source I(N) is consistent with freeze-out of HF, while it remains in the gas phase in source I. Conclusions. We use the HF molecule as a tracer of column density in diffuse gas (n(H) ~ 10^2 - 10^3 cm^-3), and find that it may uniquely trace a relatively low density portion of the gas reservoir available for star formation that otherwise escapes detection. At higher densities prevailing in protostellar envelopes (>10^4 cm^-3), we find evidence of HF depletion from the gas phase under sufficiently cold conditions., Comment: 14 pages, 10 figures. Accepted for publication in A&A

Published
2016
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11. The data processing pipeline for the Herschel SPIRE Fourier Transform Spectrometer

Author

Fulton, T., Naylor, D. A., Polehampton, E. T., Valtchanov, I., Hopwood, R., Lu, N., Baluteau, J. -P., Mainetti, G., Pearson, C., Papageorgiou, A., Guest, S., Zhang, L., Imhof, P., Swinyard, B. M., Griffin, M. J., and Lim, T. L.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

We present the data processing pipeline to generate calibrated data products from the Spectral and Photometric Imaging Receiver (SPIRE) imaging Fourier Transform Spectrometer on the Herschel Space Observatory. The pipeline processes telemetry from SPIRE observations and produces calibrated spectra for all resolution modes. The spectrometer pipeline shares some elements with the SPIRE photometer pipeline, including the conversion of telemetry packets into data timelines and calculation of bolometer voltages. We present the following fundamental processing steps unique to the spectrometer: temporal and spatial interpolation of the scan mechanism and detector data to create interferograms; Fourier transformation; apodization; and creation of a data cube. We also describe the corrections for various instrumental effects including first- and second-level glitch identification and removal, correction of the effects due to emission from the Herschel telescope and from within the spectrometer instrument, interferogram baseline correction, temporal and spatial phase correction, non-linear response of the bolometers, and variation of instrument performance across the focal plane arrays. Astronomical calibration is based on combinations of observations of standard astronomical sources and regions of space known to contain minimal emission., Comment: 14 pages, 13 figures, MNRAS in press

Published
2016
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12. Systematic characterisation of the Herschel SPIRE Fourier Transform Spectrometer

Author

Hopwood, R., Polehampton, E. T., Valtchanov, I., Swinyard, B. M., Fulton, T., Lu, N., Marchili, N., van der Wiel, M. H. D., Benielli, D., Imhof, P., Baluteau, J. -P., Pearson, C., Clements, D. L., Griffin, M. J., Lim, T. L., Makiwa, G., Naylor, D. A., Noble, G., Puga, E., and Spencer, L. D.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

A systematic programme of calibration observations was carried out to monitor the performance of the SPIRE FTS instrument on board the Herschel Space Observatory. Observations of planets (including the prime point-source calibrator, Uranus), asteroids, line sources, dark sky, and cross-calibration sources were made in order to monitor repeatability and sensitivity, and to improve FTS calibration. We present a complete analysis of the full set of calibration observations and use them to assess the performance of the FTS. Particular care is taken to understand and separate out the effect of pointing uncertainties, including the position of the internal beam steering mirror for sparse observations in the early part of the mission. The repeatability of spectral line centre positions is <5km/s, for lines with signal-to-noise ratios >40, corresponding to <0.5-2.0% of a resolution element. For spectral line flux, the repeatability is better than 6%, which improves to 1-2% for spectra corrected for pointing offsets. The continuum repeatability is 4.4% for the SLW band and 13.6% for the SSW band, which reduces to ~1% once the data have been corrected for pointing offsets. Observations of dark sky were used to assess the sensitivity and the systematic offset in the continuum, both of which were found to be consistent across the FTS detector arrays. The average point-source calibrated sensitivity for the centre detectors is 0.20 and 0.21 Jy [1 sigma; 1 hour], for SLW and SSW. The average continuum offset is 0.40 Jy for the SLW band and 0.28 Jy for the SSW band., Comment: 41 pages, 37 figures, 32 tables. Accepted for publication in MNRAS

Published
2015
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13. The Herschel Comprehensive (U)LIRG Emission Survey (HerCULES): CO Ladders, fine structure lines, and neutral gas cooling

Author

Rosenberg, M. J. F., van der Werf, P. P., Aalto, S., Armus, L., Charmandaris, V., Díaz-Santos, T., Evans, A. S., Fischer, J., Gao, Y., González-Alfonso, E., Greve, T. R., Harris, A. I., Henkel, C., Israel, F. P., Isaak, K. G., Kramer, C., Meijerink, R., Naylor, D. A., Sanders, D. B., Smith, H. A., Spaans, M., Spinoglio, L., Stacey, G. J., Veenendaal, I., Veilleux, S., Walter, F., Weiß, A., Wiedner, M. C., van der Wiel, M. H. D., and Xilouris, E. M.

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

(Ultra) Luminous Infrared Galaxies ((U)LIRGs) are objects characterized by their extreme infrared (8-1000 $\mu$m) luminosities ($L_{LIRG}>10^{11} $L$_\odot$ and $L_{ULIRG}>10^{12}$ L$_\odot$). The Herschel Comprehensive ULIRG Emission Survey (HerCULES; PI van der Werf) presents a representative flux-limited sample of 29 (U)LIRGs that spans the full luminosity range of these objects (10$^{11}\leq L_\odot \geq10^{13}$). With the \emph{Herschel Space Observatory}, we observe [CII] 157 $\mu$m, [OI] 63 $\mu$m, and [OI] 145 $\mu$m line emission with PACS, CO J=4-3 through J=13-12, [CI] 370 $\mu$m, and [CI] 609 $\mu$m with SPIRE, and low-J CO transitions with ground-based telescopes. The CO ladders of the sample are separated into three classes based on their excitation level. In 13 of the galaxies, the [OI] 63 $\mu$m emission line is self absorbed. Comparing the CO excitation to the IRAS 60/100 $\mu$m ratio and to far infrared luminosity, we find that the CO excitation is more correlated to the far infrared colors. We present cooling budgets for the galaxies and find fine-structure line flux deficits in the [CII], [SiII], [OI], and [CI] lines in the objects with the highest far IR fluxes, but do not observe this for CO $4\leq J_{upp}\leq13$. In order to study the heating of the molecular gas, we present a combination of three diagnostic quantities to help determine the dominant heating source. Using the CO excitation, the CO J=1-0 linewidth, and the AGN contribution, we conclude that galaxies with large CO linewidths always have high-excitation CO ladders, and often low AGN contributions, suggesting that mechanical heating is important.

Published
2015
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14. Physical structure of the photodissociation regions in NGC 7023. Observations of gas and dust emission with Herschel

Author

Köhler, M., Habart, E., Arab, H., Bernard-Salas, J., Ayasso, H., Abergel, A., Zavagno, A., Polehampton, E., van der Wiel, M. H. D., Naylor, D. A., Makiwa, G., Dassas, K., Joblin, C., Pilleri, P., Berne, O., Fuente, A., Gerin, M., Goicoechea, J. R., and Teyssier, D.

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

The determination of the physical conditions in molecular clouds is a key step towards our understanding of their formation and evolution of associated star formation. We investigate the density, temperature, and column density of both dust and gas in the photodissociation regions (PDRs) located at the interface between the atomic and cold molecular gas of the NGC 7023 reflection nebula. We study how young stars affect the gas and dust in their environment. Our approach combining both dust and gas delivers strong constraints on the physical conditions of the PDRs. We find dense and warm molecular gas of high column density in the PDRs., Comment: Abstract shortened

Published
2014
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20. A Long-Term Vision for Space-Based Interferometry

Author

Rinehart, S. A, Arenberg, J, Baines, E, Chen, C. H, Cleeves, L. IIsedore, Creech-Eakman, M. J, Dale, D, Danchi, W, Farrah, D, Juanola-Parramon, R, Kraus, S, Knight, J. S, Lipscy, S, Leisawitz, D. T, MacGregor, M. A, Mennesson, B, Monnier, J, Naylor, D. A, O'Connor, R, Roberge, A, Savini, G, Schmitt, H, Sewilo, M, ten Brummelaar, T. A, van Belle, G, and Yorke, H. W

Subjects
Astrophysics
Abstract

The processes leading to the formation of planets; the extreme physics occurring near the event horizon of black holes; detailed studies of exoplanets through spectral-spatial mapping: new and unique insights into the physical processes involved across nearly the whole gamut of astrophysics await discovery at small angular scales. The fine spatial resolution needed to explore these processes, however, lies beyond the capabilities of current astronomical facilities and nearly all proposed future facilities. Interferometers can crack this angular resolution problem, and space-based interferometry missions promise to explore entirely new regions of scientific phase space, providing unique new insights into the physical processes lurking at small angular scales.

Published
2019

27. The formation of planetary systems with SPICA

Author

Kamp, I., primary, Honda, M., additional, Nomura, H., additional, Audard, M., additional, Fedele, D., additional, Waters, L. B. F. M., additional, Aikawa, Y., additional, Banzatti, A., additional, Bowey, J.E., additional, Bradford, M., additional, Dominik, C., additional, Furuya, K., additional, Habart, E., additional, Ishihara, D., additional, Johnstone, D., additional, Kennedy, G., additional, Kim, M., additional, Kral, Q., additional, Lai, S.-P., additional, Larsson, B., additional, McClure, M., additional, Miotello, A., additional, Momose, M., additional, Nakagawa, T., additional, Naylor, D., additional, Nisini, B., additional, Notsu, S., additional, Onaka, T., additional, Pantin, E., additional, Podio, L., additional, Riviere Marichalar, P., additional, Rocha, W. R. M., additional, Roelfsema, P., additional, Shimonishi, T., additional, Tang, Y.-W., additional, Takami, M., additional, Tazaki, R., additional, Wolf, S., additional, Wyatt, M., additional, and Ysard, N., additional

Published
2021
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28. Short communication: Characterizing ovine serum stress biomarkers during endotoxemia

Author

Naylor, D., Sharma, A., Li, Z., Monteith, G., Sullivan, T., Canovas, A., Mallard, B. A., Baes, C., and Karrow, N. A.

Subjects
630 Agriculture, 590 Animals (Zoology)
Abstract

Breeding stress-resilient livestock is a potential strategy to help mitigate the negative effect of environmental and pathogenic stressors. The hypothalamic-pituitary-adrenal axis and immune system are activated during stress events and release mediators into the circulation that help restore physiological homeostasis. The purpose of this study was to assess a comprehensive set of circulatory mediators released in response to an acute immune stress challenge to identify candidate biomarkers that can be used for the selection of stress-resilient animals. Fifteen female lambs were stress challenged with an intravenous bolus of lipopolysaccharide (LPS; 400 ng/kg), and blood was collected from the jugular vein at 0, 2, 4, and 6 h after LPS challenge to identify and monitor candidate stress biomarkers; temperature was also recorded over time. Biomarker responses were evaluated with a repeated-measures model to compare time points with baseline values. As expected, all sheep had a monophasic febrile response to LPS challenge, and cortisol increased and returned to baseline by 6 h. The cytokines tumor necrosis factor-α, IL-6, IFN-γ (proinflammatory), and IL-10 (anti-inflammatory) increased, but only tumor necrosis factor-α returned to baseline during the monitoring period. The cytokines IL-1α, IL-1β, IL-17α (proinflammatory), and IL-4 (anti-inflammatory) did not respond to LPS challenge. All chemokines (CCL2, CCL3, CCL4, CXCL10, and IL-8) responded to LPS challenge; however, only CCL2, CCL3, CCL4, and CXCL10 increased over time, and only CCL3, CCL4, and CXCL10 returned to baseline during the monitoring period. MicroRNA (miR-145, miR-233, and miR-1246) also increased and remained elevated during the study. In summary, the LPS challenge induced a strong stress response in Rideau-Dorset sheep that could be monitored with a distinct profile of circulatory biomarkers.

Published
2020
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29. In church

Author

Naylor, D. Keith

Subjects
Philosophy and religion
Abstract

In church Pew-bound at nine in a midwestern Black Baptist church, I, whose childhood fidgeting was, in part, a longing for a wider world, listened to the congregation of sisters [...]

Published
2021

30. The Herschel SPIRE Fourier Transform Spectrometer Spectral Feature Finder I. The Spectral Feature Finder and Catalogue

Author

Hopwood, R, primary, Valtchanov, I, additional, Spencer, L D, additional, Scott, J, additional, Benson, C, additional, Marchili, N, additional, Hładczuk, N, additional, Polehampton, E T, additional, Lu, N, additional, Makiwa, G, additional, Naylor, D A, additional, Gom, B G, additional, Noble, G, additional, and Griffin, M J, additional

Published
2020
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33. Epidemiology of intra-abdominal infection and sepsis in critically ill patients: 'AbSeS', a multinational observational cohort study and ESICM Trials Group Project

Author

Blot, S. Antonelli, M. Arvaniti, K. Blot, K. Creagh-Brown, B. de Lange, D. De Waele, J. Deschepper, M. Dikmen, Y. Dimopoulos, G. Eckmann, C. Francois, G. Girardis, M. Koulenti, D. Labeau, S. Lipman, J. Lipovestky, F. Maseda, E. Montravers, P. Mikstacki, A. Paiva, J.-A. Pereyra, C. Rello, J. Timsit, J.-F. Vogelaers, D. Lamrous, A. Rezende-Neto, J. Cardenas, Y. Vymazal, T. Fjeldsoee-Nielsen, H. Kott, M. Kostoula, A. Javeri, Y. Einav, S. Makikado, L.D.U. Tomescu, D. Gritsan, A. Jovanovic, B. Venkatesan, K. Mirkovic, T. Creagh-Brown, B. Lamrous, A. Emmerich, M. Canale, M. Dietz, L.S. Ilutovich, S. Miñope, J.T.S. Silva, R.B. Montenegro, M.A. Martin, P. Saul, P. Chediack, V. Sutton, G. Couce, R. Balasini, C. Gonzalez, S. Lascar, F.M. Descotte, E.J. Gumiela, N.S. Pino, C.A. Cesio, C. Valgolio, E. Cunto, E. Dominguez, C. Nelson, N.F. Abegao, E.M. Pozo, N.C. Bianchi, L. Correger, E. Pastorino, M.L. Miyazaki, E.A. Pozo, N.C. Grubissich, N. Garcia, M. Bonetto, N. Quevedo, N.E. Gomez, C.D. Queti, F. Estevarena, L.G. Fernandez, R. Santolaya, I. Pozo, N.C. Grangeat, S.H. Doglia, J. Zakalik, G. Pellegrini, C. Lloria, M.M. Chacon, M.E. Fumale, M. Leguizamon, M. Hidalgo, I.B. Tiranti, R.J. Capponi, P. Tita, A. Cardonnet, L. Bettini, L. Ramos, A. Lovesio, L. Miranda, E.M. Farfan, A.B. Tolosa, C. Segura, L. Bellocchio, A. Alvarez, B. Manzur, A. Lujan, R. Fernandez, N. Scarone, N. Zazu, A. Groh, C. Fletcher, J. Smith, J. Azad, R. Chavan, N. Wong, H. Kol, M. Campbell, L. Starr, T. Roberts, B. Wibrow, B. Warhurst, T. Chinthamuneedi, M. Ferney, B.B. Simon, M. De Backer, D. Wittebole, X. De Bels, D. Collin, V. Dams, K. Jorens, P. Dubois, J. Gunst, J. Haentjens, L. De Schryver, N. Dugernier, T. Rezende-Neto, J. Rizoli, S. Santillan, P. Han, Y. Biskup, E. Qu, C. Li, X. Yu, T. Weihua, L. Molano-Franco, D. Rojas, J. Oviedo, J.M.P. Pinilla, D. Cardenas, Y. Celis, E. Arias, M. Vukovic, A. Vudrag, M. Belavic, M. Zunic, J. Kuharic, J. Kricka, I.B. Filipovic-Grcic, I. Tomasevic, B. Obraz, M. Bodulica, B. Dohnal, M. Malaska, J. Kratochvil, M. Satinsky, I. Schwarz, P. Kos, Z. Blahut, L. Maca, J. Protus, M. Kieslichová, E. Nielsen, L.G. Krogh, B.M. Rivadeneira, F. Morales, F. Mora, J. Orozco, A.S. MorochoTutillo, D.R. Vargas, N.R. Yepez, E.S. Villamagua, B. Alsisi, A. Fahmy, A. Dupont, H. Lasocki, S. Paugam-Burtz, C. Foucrier, A. Nica, A. Barjon, G. Mallat, J. Marcotte, G. Leone, M. Duclos, G. Burtin, P. Atchade, E. Mahjoub, Y. Misset, B. Timsit, J.-F. Dupuis, C. Veber, B. Debarre, M. Collange, O. Pottecher, J. Hecketsweiler, S. Fromentin, M. Tesnière, A. Koch, C. Sander, M. Kott, M. Elke, G. Wrigge, H. Simon, P. Chalkiadaki, A. Tzanidakis, C. Pneumatikos, I. Sertaridou, E. Mastora, Z. Pantazopoulos, I. Papanikolaou, M. Papavasilopoulou, T. Floros, J. Kolonia, V. Diakaki, C. Rallis, M. Paridou, A. Kalogeromitros, A. Romanou, V. Nikolaou, C. Kounougeri, K. Tsigou, E. Psallida, V. Karampela, N. Mandragos, K. Kontoudaki, E. Pentheroudaki, A. Farazi-Chongouki, C. Karakosta, A. Chouris, I. Radu, V. Malliotakis, P. Kokkini, S. Charalambous, E. Kyritsi, A. Koulouras, V. Papathanakos, G. Nagky, E. Lampiri, C. Tsimpoukas, F. Sarakatsanos, I. Georgakopoulos, P. Ravani, I. Prekates, A. Sakellaridis, K. Christopoulos, C. Vrettou, E. Stokkos, K. Pentari, A. Marmanidou, K. Kydona, C. Tsoumaropoulos, G. Bitzani, M. Kontou, P. Voudouris, A. Elli-Nikki Flioni Antypa, E. Chasou, E. Anisoglou, S. Papageorgiou, E. Paraforou, T. Tsioka, A. Karathanou, A. Vakalos, A. Shah, B. Thakkar, C. Jain, N. Gurjar, M. Baronia, A. Sathe, P. Kulkarni, S. Paul, C. Paul, J. Masjedi, M. Nikandish, R. Zand, F. Sabetian, G. Mahmoodpoor, A. Hashemian, S.M. Bala, M. Flocco, R. Torrente, S. Pota, V. Spadaro, S. Volta, C. Serafini, G. Boraso, S. Tiberio, I. Cortegiani, A. Misseri, G. Barbagallo, M. Nicolotti, D. Forfori, F. Corradi, F. De Pascale, G. Pelagalli, L. Brazzi, L. Vittone, F.G. Russo, A. Simion, D. Cotoia, A. Cinnella, G. Toppin, P. Johnson-Jackson, R. Hayashi, Y. Yamamoto, R. Yasuda, H. Kishihara, Y. Shiotsuka, J. Sanchez-Hurtado, L.A. Tejeda-Huezo, B. Gorordo, L. Ñamendys-Silva, S.A. Garcia-Guillen, F.J. Martinez, M. Romero-Meja, E. Colorado-Dominguez, E. van den Oever, H. Kalff, K.M. Vermeijden, W. Cornet, A.D. Beck, O. Cimic, N. Dormans, T. Bormans, L. Bakker, J. Van Duijn, D. Bosman, G. Vos, P. Haas, L. Henein, A. Miranda, A.M. Makikado, L.D.U. Malca, G.E.G. Arroyo-Sanchez, A. Misiewska-Kaczur, A. Akinyi, F. Czuczwar, M. Luczak, K. Sulkowski, W. Tamowicz, B. Swit, B. Baranowski, B. Smuszkiewicz, P. Trojanowska, I. Rzymski, S. Sawinski, M. Trosiak, M. Mikaszewska-Sokolewicz, M. Alves, R. Leal, D. Krystopchuk, A. Mendonca, P.M.H. Pereira, R.A. de Carvalho, M.R.L.M. Candeias, C. Molinos, E. Ferreira, A. Castro, G. Pereira, J.-M. Santos, L. Ferreira, A. Pascoalinho, D. Ribeiro, R. Domingos, G. Gomes, P. Nora, D. Costa, R.P. Santos, A. Alsheikhly, A.S. Tomescu, D. Popescu, M. Grigoras, I. Patrascanu, E. Zabolotskikh, I. Musaeva, T. Gaigolnik, D. Kulabukhov, V. Belskiy, V. Zubareva, N. Tribulev, M. Abdelsalam, A. Aldarsani, A. Al-Khalid, M. Almekhlafi, G. Mandourah, Y. Jovanovic, B. Doklestic, K. Velickovic, J. Velickovic, D. Jankovic, R. Vukovic, A. Skoric-Jokic, S. Radovanovic, D. Richards, G. Alli, A. del Carmen Cordoba Nielfa, M. Iniesta, R.S. Martínez, A.B.-C. Bernedo, C.G. Gil, S.A.P. Nuvials, X. Garcia, J.G. Peña, J.M.G. Jimenez, R. Herrera, L. Barrachina, L.G. Monzon, I.C. Redondo, F.J. Villazala, R. Zapata, D.F.M. Lopez, I.M.V. Moreno-Gonzalez, G. Lopez-Delgado, J.C. Marin, J.S. Sanchez-Zamora, P. Vidal, M.V. González, J.F. Salinas, I. Hermosa, C. Martinez-Sagasti, F. Domingo-Marín, S. Victorino, J.A. Garcia-Alvarez, R. Calleja, P.L.-A. de la Torre-Prados, M.-V. Vidal-Cortes, P. del Río-Carbajo, L. Izura, J. Minguez, V. Alvarez, J.T. Prous, A.P. Paz, D. Roche-Campo, F. Aguilar, G. Belda, J. Rico-Feijoo, J. Aldecoa, C. Zalba-Etayo, B. Lang, M. Dullenkopf, A. Trongtrakul, K. Chtsomkasem, A. Akbas, T. Unal, M.N. Ozcelik, M. Gumus, A. Ramazanoglu, A. Memis, D. Mehmet, I. Urkmez, S. Ozgultekin, A. Demirkiran, O. Aslan, N.A. Kizilaslan, D. Kahveci, F. Ünlü, N. Ozkan, Z. Kaye, C. Jansen, J. O’Neill, O. Nutt, C. Jha, R. Hooker, N. Grecu, I. Petridou, C. Shyamsundar, M. McNamee, L. Trinder, J. Hagan, S. Kelly, C. Silversides, J. Groba, C.B. Boyd, O. Bhowmick, K. Humphreys, S. Summers, C. Polgarova, P. Margarson, M. Dickens, J. Pearson, S. Chinery, E. Hemmings, N. O’Kane, S. Austin, P. Cole, S. Plowright, C. Box, R. Wright, C. Young, L. Montague, L. Parker, R. Morton, B. Ostermann, M. Bilinska, J. Rose, B.O. Reece-Anthony, R. Ryan, C. Hamilton, M. Hopkins, P. Wendon, J. Brescia, G. Ijaz, N. Wood, J. George, M. Toth-Tarsoly, P. Yates, B. Armstrong, M. Scott, C. Boyd, C. Szakmany, T. Rees, D. Pulak, P. Coggon, M. Saha, B. Kent, L. Gibson, B. Camsooksai, J. Reschreiter, H. Morgan, P. Sangaralingham, S. Lowe, A. Vondras, P. Jamadarkhana, S. Cruz, C. Bhandary, R. Hersey, P. Furneval, J. Innes, R. Doble, P. Attwood, B. Parsons, P. Page, V. Zhao, X. Grecu, I. Dalton, J. Hegazy, M. Awad, Y. Naylor, D. Naylor, A. Lee, S. Brevard, S. Davis, N. the Abdominal Sepsis Study (AbSeS) group on behalf of the Trials Group of the European Society of Intensive Care Medicine

Abstract

Purpose: To describe the epidemiology of intra-abdominal infection in an international cohort of ICU patients according to a new system that classifies cases according to setting of infection acquisition (community-acquired, early onset hospital-acquired, and late-onset hospital-acquired), anatomical disruption (absent or present with localized or diffuse peritonitis), and severity of disease expression (infection, sepsis, and septic shock). Methods: We performed a multicenter (n = 309), observational, epidemiological study including adult ICU patients diagnosed with intra-abdominal infection. Risk factors for mortality were assessed by logistic regression analysis. Results: The cohort included 2621 patients. Setting of infection acquisition was community-acquired in 31.6%, early onset hospital-acquired in 25%, and late-onset hospital-acquired in 43.4% of patients. Overall prevalence of antimicrobial resistance was 26.3% and difficult-to-treat resistant Gram-negative bacteria 4.3%, with great variation according to geographic region. No difference in prevalence of antimicrobial resistance was observed according to setting of infection acquisition. Overall mortality was 29.1%. Independent risk factors for mortality included late-onset hospital-acquired infection, diffuse peritonitis, sepsis, septic shock, older age, malnutrition, liver failure, congestive heart failure, antimicrobial resistance (either methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, extended-spectrum beta-lactamase-producing Gram-negative bacteria, or carbapenem-resistant Gram-negative bacteria) and source control failure evidenced by either the need for surgical revision or persistent inflammation. Conclusion: This multinational, heterogeneous cohort of ICU patients with intra-abdominal infection revealed that setting of infection acquisition, anatomical disruption, and severity of disease expression are disease-specific phenotypic characteristics associated with outcome, irrespective of the type of infection. Antimicrobial resistance is equally common in community-acquired as in hospital-acquired infection. © 2019, The Author(s).

Published
2019

34. Rivaroxaban for stroke prevention after embolic stroke of undetermined source

Author

Hart, Robert G, Sharma, Mukul, Mundl, Hardi, Kasner, Scott E, Bangdiwala, Shrikant I, Berkowitz, Scott D, Swaminathan, Balakumar, Lavados, Pablo, Wang, Yongjun, Wang, Yilong, Davalos, Antonio, Shamalov, Nikolay, Mikulik, Robert, Cunha, Luis, Lindgren, Arne, Arauz, Antonio, Lang, Wilfried, Czlonkowska, Anna, Eckstein, Jens, Gagliardi, Rubens J, Amarenco, Pierre, Ameriso, Sebastian F, Tatlisumak, Turgut, Veltkamp, Roland, Hankey, Graeme J, Toni, Danilo, Bereczki, Daniel, Uchiyama, Shinichiro, Ntaios, George, Yoon, Byung-Woo, Brouns, Raf, Endres, Matthias, Muir, Keith W, Bornstein, Natan, Ozturk, Serefnur, O'Donnell, Martin J, De Vries Basson, Matthys M, Pare, Guillaume, Pater, Calin, Kirsch, Bodo, Sheridan, Patrick, Peters, Gary, Weitz, Jeffrey I, Peacock, W Frank, Shoamanesh, Ashkan, Benavente, Oscar R, Joyner, Campbell, Themeles, Ellison, Connolly, Anderson DC, Stuart J., Demets, Dl, Kaste, M, Norrving, B, Wyse, Dg, Alet, M, Allende, G, Beinlich, A, Berrios, W, Bruera, G, Castro, D, Chialvo, L, Claverie, S, Contardo, L, Couto, J, Deganutto, R, Diaz, R, Dossi, D, Esnaola, M, Falco, M, Fernandez Pirrone, P, Ferrari, J, Firstenfeld, A, Galli Giqueauk, E, Gilli, M, Gonzalez, L, Gonzalez Toledo, M, Grecco, M, Halac, B, Hawkes, M, Ioli, P, Jure, L, Klein, F, Lepera, S, Lujan, S, Mackinnon, F, Marroquin, M, Martin, J, Parisi, V, Perez Leguizamon, P, Persi, G, Povedano, P, Povedano, G, Pujol Lereis, V, Radrizzani, L, Reich, E, Repetto, M, Rodriguez Lucci, F, Romano, M, Saredo, G, Schneider, M, Simonsini, C, Sumay, G, Thomson, A, Toledo, W, Torres, C, Vila, A, Abdul Rasheed, N, Anderson, C, Bailey, P, Blacker, D, Carcel, C, Clissold, B, Delcourt, C, Field, D, Gangadharan, S, Ghia, D, Kleinig, T, Leyden, J, Ly, J, Ma, H, Mackey, E, Mishra, S, Moey, A, Musuka, T, Pepper, E, Phan, T, Sabet, A, Saw, J, Singh, B, Tryambake, D, Tu, H, Wijeratne, T, Wong, A, Augustin, S, Esterbauer, M, Garnauf, M, Gasiorek, K, Gasser, S, Gaugg, M, Greisenegger, S, Harrasser, M, Heine, M, Huber, B, Joachim, B, Kapeller, P, Krebs, S, Kreuzpointer, R, Kunzmann, J, Lechner, H, Lohninger, B, Luschin, G, Macher, S, Marko, M, Matosevic, B, Mayr, A, Mismas, A, Mitrovic, N, Mutzenbach, J, Oberndorfer, S, Obmann, S, Raffelsberger, T, Roesler, C, Salletmayr, T, Serles, W, Stadler, K, Tinchon, A, Tolino, M, Verocai, V, Vigl, M, Voglsperger, B, Weber, J, Werner, P, Windt, J, Winkler, A, Wurzinger, H, Zelenka, I, Cras, P, Crols, R, De Keyser, J, De Klippel, N, De Pauw, A, De Smedt, A, Dhollander, I, Hermans, S, Ligot, N, Maqueda, V, Maqueda Maqueda, V, Naeije, G, Seynaeve, L, Soors, P, Van Daele, W, Vanacker, P, Vanderschueren, G, Willems, C, Yperzeele, L, Avelar, W, Bacellar, A, Batista, C, Bazan, R, Braga, G, Cardoso, F, Dagnino, M, Fabio, S, Ferreira Junior, G, Freitas, G, Friedrich, M, Gomes Neto, A, Guarda, S, Katsurayama, M, Machado, M, Martins, S, Meira, F, Minelli, C, Morais, R, Moro, C, Neto, O, Polin, M, Silva, D, Weiss, G, Basile, V, Beaudry, M, Berlingieri, J, Blacquiere, D, Buck, B, Chan, R, Coutts, S, Das, S, Desai, J, Ehrensperger, E, Field, T, Gladstone, D, Hachinski, V, Hassan, A, Hegedus, J, Hill, M, Jin, A, Khaw, A, Mackey, A, Maclean, G, Mandzia, J, Mann, S, Mehdiratta, M, Murphy, C, Ng, K, Oczkowski, W, Penn, A, Perera, K, Perez, Y, Pesant, Y, Phillips, S, Poppe, A, Sahlas, J, Shuaib, A, Spence, D, Sposato, L, Stotts, G, Tamayo, A, Teal, P, Wilson, L, Winder, T, Yegappan, C, Yip, S, Andreu, D, Araya, P, Bustamante, G, Figueroa, C, Gasic, K, Herrero, D, Matamala, G, Munoz, S, Olavarria, V, Pasten, J, Polanco, J, Reyes, P, Roldan, A, Salamanca, P, Silva, P, Toloza, C, Verdugo, M, Cai, K, Che, C, Chen, J, Chen, Z, Chen, T, Chen, H, Chen, X, Chen, B, Chen, G, Chen, L, Chu, F, Cui, L, Dai, C, Ding, N, Ding, J, Du, P, Du, J, Fang, L, Feng, J, Gao, Y, Geng, J, Guan, J, Hao, L, Huang, D, Huang, H, Jin, X, Jing, P, Ke, K, Li, G, Li, M, Li, S, Li, J, Liang, Z, Lin, H, Liu, K, Liu, X, Lu, Z, Ma, C, Pei, H, Qiu, J, Qu, X, Shen, W, Sun, X, Tian, J, Tong, L, Tong, Z, Wang, J, Wang, L, Wang, X, Wang, W, Wang, N, Wang, D, Wang, H, Wen, G, Weng, G, Wu, W, Wu, S, Xiao, B, Xiaopeng, W, Xiong, L, Xiong, Y, Xu, Y, Xu, J, Xu, Z, Yang, L, Yang, Y, Yang, X, Yang, J, Yang, Q, Yang, B, Zhang, C, Zhang, B, Zhang, Y, Zhang, S, Zhang, M, Zhang, X, Zhang, J, Zhao, L, Zhou, L, Bar, M, Barteys, M, Bartolottiova, T, Carek, M, Ferencova, K, Fiksa, J, Gallo, J, Goldemund, D, Hanouskova, L, Herzig, R, Hon, P, Jankovych, J, Jura, R, Kadlcikova, J, Kemlink, D, Kopecky, S, Krajickova, D, Kral, M, Krejci, V, Pavlik, O, Peisker, T, Pernicka, M, Peska, S, Rapantova, P, Reif, M, Rekova, P, Sanak, D, Sebejova, M, Skoda, O, Slonkova, J, Stetkarova, I, Tenora, D, Tumova, R, Vaclavik, D, Vasko, P, Veverka, T, Vitkova, E, Volna, J, Andersen, G, Christensen, H, Christensen, T, Damgaard, D, Iversen, H, Krarup Hansen, C, Kruuse, C, Martinussen, M, Modrau, B, Murtuzova, A, Ovesen, C, Papina, M, Svaneborg, N, Von Weitzel-Mudersbach, P, Curtze, S, Fanta, S, Huhtakangas, J, Keskinarkaus, I, Kivioja, R, Koivu, M, Korpela, J, Larjo, T, Linna, M, Marinkovic, I, Martinez-Majander, N, Nieminen, T, Nikkanen, M, Numminen, H, Ortiz, R, Österlund-Tauriala, E, Roine, R, Roine, S, Ruuskanen, J, Saarinen, J, Shulga, A, Sibolt, G, Tapanainen, A, Tapiola, T, Tiainen, M, Tomppo, L, Tumpula, O, Tuomainen, P, Tynkkynen, J, Vainikka, S, Valpas, J, Virta, J, Ylikallio, E, Ylikotila, P, Accassat, S, Aniculaesei, A, Baronnet, F, Bejot, Y, Bindila, D, Birchenall, J, Blanc-Labarre, C, Bodiguel, E, Bouly, S, Cabrejo, L, Calvet, D, Corlobe, A, Crozier, S, Delpont, B, Deltour, S, Diaconu, M, Domigo, V, Epinat, M, Ferreira, A, Fisselier, M, Garnier, P, Gimenez, L, Gueguen, A, Guidoux, C, Guillon, B, Guiraudg, V, Hervieu-Begue, M, Hobeanu, M, Khoumri, C, Lamy, C, Lauer, V, Le Bouc, R, Lecouturier, K, Leder, S, Leger, A, Macian-Montoro, F, Meseguer, E, Morar-Precup, D, Morvan, T, Morvan, E, Obadia, M, Osseby, G, Philippi, S, Pico, F, Quenardelle, V, Reiner, P, Rigual, R, Rosso, C, Sabben, C, Samson, Y, Sevin, M, Sibon, I, Thouvenot, E, Timsit, S, Touze, E, Turc, G, Vahedi, K, Varvat, J, Wacongne, A, Wolff, V, Yalo, B, Zinchenko, I, Bagelmann, H, Bardutzky, J, Barlinn, J, Bathe-Peters, R, Berrouschot, J, Dietzel, J, Ehrlich, S, Fatar, M, Filipov, A, Fluri, F, Gabriel, M, Geran, R, Gliem, M, Graf, S, Griebe, M, Grosse, G, Haeusler, K, Harmel, P, Held, V, Hellwig, S, Henkner, J, Hieber, M, Hoyer, C, Jander, S, Keilitz, J, Kellner, J, Knecht, S, Koch, M, Koehler, L, Kucken, D, Kusnick, G, Lambeck, J, Lee, J, Leisse, I, Lubke-Detring, S, Machetanz, J, Mensch, A, Meyer, N, Molis, A, Mueller, T, Muhl, C, Nave, A, Radtke, A, Roth, Y, Roukens, R, Schlachetzki, F, Schneider, I, Schuppner, R, Schurig, J, Schwarzbach, C, Seidel, G, Sonntag, N, Steinert, S, Stoll, A, Stumpp, A, Taggeselle, J, Trommer, A, Tuetuencue, S, Wartenberg, K, Weissenborn, K, Wittayer, M, Wolf, M, Wolter, C, Worthmann, H, Wunderlich, S, Zitzmann, A, Anagnostou, E, Brokalaki, C, Hatzitolios, A, Kakaletsis, N, Kanellos, I, Kei, A, Korompoki, E, Koutroubi, A, Liamis, G, Makaritsis, K, Manios, E, Michas, F, Milionis, H, Papadopoulos, G, Papadopoulou, E, Papagiannis, A, Polychronopoulou, E, Sagris, D, Satsoglou, S, Savopoulos, C, Solganov, I, Spengos, K, Stamatelopoulos, K, Terentiou, A, Tountopoulou, A, Vassilopoulou, S, Amjad, A, Balazs, A, Bankuti, Z, Bicsak, T, Borcsik, L, Csanyi, A, Csiba, L, Csontos, K, Csuha, R, Czurko, M, Danku, V, Dioszeghy, P, Faust, K, Fazekas, F, Gerocs, Z, Gottschal, M, Gyuker, N, Hajas, A, Horvath, L, Horvath, M, Iljicsov, A, Jakab, K, Javor, L, Kakuk, I, Karasz, O, Kasa, K, Kasza, J, Kerekgyarto, M, Klivenyi, P, Kovacs, K, Kovacs, T, Kovacs, H, Lajos, B, Lovasz, R, Magyar, T, Matoltsy, A, May, Z, Molnar, S, Monosi, C, Motko, T, Nemeth, R, Nemeth, L, Nikl, J, Olah, L, Orosz, V, Panczel, G, Pentek, S, Prendl, B, Rozsa, C, Rum, G, Sas, K, Sas, A, Semjen, J, Simony, Z, Sipos, I, Szabo, K, Szasz, G, Szegedi, N, Szekely, A, Szilagyi, G, Szoboszlai, K, Szpisjak, L, Toth, G, Uhrinyakova, L, Valikovics, A, Varga, Z, Vass, L, Vastagh, I, Vecsei, L, Zboznovits, D, Coveney, S, Horgan, G, Kelly, P, Murphy, S, Smyth, A, Waters, R, Abu Ahmad, F, Bloch, S, Dorodnicov, E, Hallevi, H, Haratz, S, Horev, A, Kolianov, V, Leker, R, Mahagney, A, Marzelik, O, Rephaeli, G, Tanne, D, Weller, B, Acciarresi, M, Adami, A, Agostoni, E, Alemseged, F, Altavilla, R, Angelocola, S, Anticoli, S, Berardi, V, Bravi, M, Candeloro, E, Cappellari, M, Carletti, M, Caruso, P, Castellini, P, Cavallini, A, Cenciarelli, S, Cerrone, P, Condurso, R, Consoli, D, Danese, A, Della Marca, G, Denaro, M, Di Mascio, M, Diomedi, M, Distefano, M, Frisullo, G, Furlanis, G, Galati, F, Gallina, A, Gallinella, E, Giannandrea, D, Giatsidis, F, Greco, L, Impellizzeri, M, Landolfi, A, Lanfranconi, S, Latte, L, Lembo, G, Longoni, M, Marando, C, Marini, C, Marsili, E, Mastrocola, S, Mazzoli, T, Melis, M, Micheletti, N, Moller, J, Monzani, V, Naccarato, M, Paciaroni, M, Padiglioni, C, Persico, A, Pezzella, F, Pieroni, A, Piras, V, Postorino, P, Pozzerese, C, Profice, P, Ricci, S, Rinaldi, C, Rizzato, B, Rocco, A, Roveri, L, Santalucia, P, Semerano, A, Sicilia, I, Silvestrini, M, Sucapane, P, Tomelleri, G, Tropepi, D, Venti, M, Amino, T, Chin, M, Deguchi, I, Fujigasaki, H, Fukuyama, K, Haraguchi, K, Hasegawa, Y, Hattori, M, Hayashi, T, Hirose, M, Honma, Y, Igarashi, S, Irie, S, Itabashi, R, Ito, Y, Kamata, T, Kaneko, C, Kawanishi, M, Kimura, R, Kitagawa, K, Kobayashi, Y, Kondo, T, Kuwashiro, T, Matsumoto, S, Miyake, H, Nagakane, Y, Nishino, S, Nishiyama, Y, Nogawa, S, Ochiai, J, Ohira, M, Okamoto, Y, Okubo, S, Okuda, S, Ooyama, K, Sakai, N, Suenaga, T, Suzuki, H, Takamatsu, K, Takao, M, Taki, W, Takizawa, S, Tokunaga, K, Toyoda, K, Urui, S, Yamada, T, Yamasaki, M, Yoshida, Y, Yuasa, H, Bae, H, Cha, J, Chang, D, Chung, C, Heo, J, Hong, K, Kim, J, Lee, B, Nah, H, Oh, K, Park, M, Park, J, Rha, J, Sohn, S, Amaya Sanchez, L, Arauz Gongora, A, Cantu Brito, C, Chiquete Anaya, E, Felipe Amaya, P, Fernandez Vera, J, Garcia Lopez, R, Gien Lopez, J, Gongora-Rivera, J, Hernandez, J, Leal Cantu, R, Lopez Garza, N, Medina Pech, C, Mendez, B, Pena Sedna, L, Reyes Morales, S, Ruiz Franco, A, Serrano, F, Tovar, M, Uribe, R, Bak, Z, Baranowska, A, Bilik, M, Blazejewska-Hyzorek, B, Brola, W, Brzoska-Mizgalska, J, Buksinska-Lisik, M, Chorazy, M, Czerska, M, Czuryszkiewicz, M, Dalek, G, Dylewicz, L, Fiszer, U, Fraczek, A, Friedman, A, Fryze, W, Gasecki, D, Gębura, K, Geremek, M, Glabinski, A, Gluszkiewicz, M, Goździk, I, Grzesik, M, Jasek, L, Kaczorowska, B, Kalinowska, K, Kaminska, K, Kapica-Topczewska, K, Karlinski, M, Kobayashi, A, Kosarz-Lanczek, K, Kowalczyk, K, Kowalska, M, Kraska, J, Krzyzanowska, M, Kulakowska, A, Kurkowska-Jastrzebska, I, Lasek-Bal, A, Litwin, T, Morton, M, Myśliwy, W, Nosek, K, Nowak, B, Nowakowska-Śledź, E, Odyniec, A, Oleszek, J, Ozdoba-Rot, J, Palasik, W, Pawelczyk, M, Rozanski, D, Rozniecki, J, Sawicka, M, Sieczkowska, E, Skowron, P, Skowronska, M, Sliwinska, B, Sobolewski, P, Sobota, A, Stoiński, J, Szczuchniak, W, Szczyrba, S, Szewczyk, Z, Szlufik, S, Tarasiuk, J, Tutaj, A, Uchwat, U, Wach-Klink, A, Winska-Tereszkiewicz, A, Wisniewska, A, Włodek, A, Wojnarowska-Arendt, A, Zalewska, J, Zielinska-Turek, J, Ziomek, M, Zwiernik, J, Abreu, P, E Silva A, Amaral, Azevedo, E, Barroso, C, Calejo, M, Campillo, J, Campos Costa, E, Coelho, J, Correia, M, Correia, C, Gregorio, T, Lopes, D, Machado, C, Mendonca, T, Pereira, L, Pidal, A, Pineiro, S, Pinto, A, Ribeiro, J, Rodrigues, M, Salgado, P, Salgado, A, Santo, G, Sargento, J, Varela, R, Abroskina, M, Badalyan, K, Balueva, T, Barulin, A, Bazhenova, O, Belkin, A, Bogdanov, E, Daineko, A, Druzenko, I, Fedin, A, Fidler, M, Gogoleva, E, Golikov, K, Gonysheva, Y, Greshnova, I, Guryanova, N, Gusev, V, Kashaeva, E, Kaygorodtseva, S, Khairutdinova, D, Kholopov, M, Kirpicheva, S, Koltsov, I, Konkov, I, Kurenkova, N, Kurtenkova, N, Kurushina, O, Kustova, M, Lagutenko, M, Lenskaya, L, Lupinogina, L, Lvova, A, Melnikova, E, Meshkova, K, Morozova, E, Mozhejko, E, Nikoforova, M, Obrezan, A, Ondar, V, Pizova, N, Polyakov, A, Popov, D, Prazdnichkova, E, Prokopenko, S, Pudov, E, Salnikov, M, Samoshkina, O, Semushina, D, Shchukin, I, Shepeleva, E, Shmonin, A, Smolkin, A, Soldatov, M, Soloveva, L, Solovyeva, E, Stakhovskaya, L, Tcvetkova, S, Varvyanskaya, N, Voznyuk, I, Zhirnova, O, Ahmed, F, Basson, M, Engelbrecht, J, Hobson, B, Jansen, J, Nel, J, Nell, H, Njovane, X, Pretorius, M, Roos, J, Salig, S, Siebert, M, Amaro, S, Arenillas Lara, J, Arias Rivas, S, Baez Martinez, E, Bas, M, Bashir, S, Bragado, I, Cajaraville, S, Camps, P, Cardona Portela, P, Casado-Naranjo, I, Castellanos, M, Cayuela Caudevilla, N, Chamorro, A, Constantino Silva, A, Cortijo Garcia, E, De La Torre, J, De Torres, R, Diaz Otero, F, Diez-Tejedor, E, Escribano, B, Escudero, I, Fernandez, M, Font, M, Fortea, G, Freijo, M, Fuentes Gimeno, B, Gamero, M, Garcia, J, Garcia Pastor, A, Garcia Sanchez, S, Geniz Clavijo, M, Gil Nunez, A, Giralt, E, Gomez-Choco, M, Gomis, M, Gutiérrez, R, Iglesias Mohedano, A, Lago, A, Lara Lezama, L, Lara Rodriguez, B, Llull, L, Lopez Fernandez, M, Lorenzo, A, Maestre-Moreno, J, Marta Moreno, J, Marti-Fabregas, J, Martínez Sánchez, P, Mauri Cabdevila, G, Mengual Chirifie, J, Molina, C, Molina, J, Moniche, F, Morales, L, Morales, A, Nombela, F, Núñez, F, Pagola, J, Perez, S, Portilla, J, Prats, L, Purroy, F, Quesada Garcia, H, Ramirez Moreno, J, Redondo Robles, L, Renu, A, Riveira Rodriguez, C, Roa, A, Rodriguez Campello, A, Rodriguez Pardo De Donlebun, J, Rodriguez Yanez, M, Rudilosso, S, Ruiz Ares, G, Sànchez Cerón, M, Santamaria Cadavid, M, Sanz Cuesta, B, Serena, J, Silva, Y, Soriano Soriano, C, Tejada Garcia, J, Tejada Meza, H, Tembl, J, Terceno, M, Trillo, S, Urra, X, Usero Ruiz, M, Vazquez, P, Vilar, C, Villanueva Osorio, J, Ximenez-Carrillo, A, Zapata, E, Esbjornsson, M, Karlsson, J, Kremer, C, Kuris, A, Staaf, G, Stiehm, M, Timberg, I, Tossavainen, C, Wester, P, Arnold, M, Baumgartner, P, Beer, J, Bicker, H, Boos, L, Cereda, C, Chaloulos-Iakovidis, P, Christian, L, Engelter, S, Fisch, L, Fischer, U, Frey, S, Frick, M, Hauk, M, Hoffmann, M, Kahles, T, Manno, C, Medlin, F, Mircea, D, Nedeltchev, K, Panos, L, Polymeris, A, Schillinger, N, Stocker, R, Sztajzel, R, Alaydin, H, Batur Caglayan, H, Colakoglu, S, Demirci, N, Duman, T, Eren, F, Gokce, M, Inanc, Y, Nazliel, B, Ongun, G, Ozcekic Demirhan, S, Ozyurt, E, Selcuk, D, Sorgun, M, Tezcan, S, Togay Isikay, C, Tokgoz, O, Ulku Acar, R, Uluduz Ugurlu, D, Abdul-Saheb, M, Ahmad, N, Ali, A, Alwis, L, Balogun, I, Bathula, R, Behnam, Y, Bhandari, M, Bhargavah, M, Black, T, Blank, C, Bruce, D, Burn, M, Canepa, C, Chakrabarti, A, Chandrasena, D, Chembala, J, Cheripelli, B, Clarke, R, Cohen, D, Collas, D, Constantin, C, Dani, K, Del Giudice, A, Dennis, M, Devine, J, Dima, S, Doubal, F, Duodu, Y, Dutta, D, El Ta Wil, S, Elyas, S, Evans, N, Eveson, D, Fotherby, K, France, E, Furnace, J, Grabowski, S, Gunathilagan, G, Gutierrez, R, Guyler, P, Hargroves, D, Harkness, K, Harvey, M, Hayhoe, H, Hicken, L, Hussain, M, Kelly, S, Lam, M, Lindert, R, Louw, S, Luder, R, Macleod, M, Majid, A, Mangion, D, Markova, S, Markus, H, Marsh, R, Mcarthur, K, Menon, N, Metcalf, K, Minhas, J, Minns, M, Mistri, A, Moreton, F, Mpelembue, M, Muddegowda, G, Mudhar, O, Musarrat, K, Myint, M, Natarajan, I, Naylor, D, Ngeh, J, Papavasileiou, V, Perry, R, Piechowski-Jozwiak, B, Pradhan, M, Rani, A, Rashed, K, Robinson, T, Roffe, C, Saksena, R, Sattar, N, Sekaran, L, Selvarajah, J, Shah, S, Sinha, D, Sivakumar, R, Sztriha, L, Walters, D, Webb, T, Werring, D, Whiteley, W, Whiting, R, Abdelhamid, N, Abdul Rahman, D, Amin, H, Androulakis, M, Babikian, V, Baker, M, Barker Trejo, S, Benjamin, A, Birnbaum, L, Burke, J, Chen, S, Clark, W, Coull, B, De Havenon, A, Dearborn, J, Degeorgia, M, Essa, B, Fares, M, Favate, A, Furlan, A, Gebreyohanns, M, Goddeau, R, Green, D, Greer, D, Haralur Sreekantaiah, Y, Hasan, R, Hedna, V, Henninger, N, Holmstedt, C, Ishida, K, Jagolino, A, Johnson, M, Jun-Oconnell, A, Kaur, S, Khanna, A, Kirshner, H, Kittner, S, Kleindorfer, D, Leira, E, Loomis, C, Lord, A, Lowenkopf, T, Lutsep, H, Magadan, A, Majjhoo, A, Maud, A, Mayasi, Y, Mccullough, L, Mckinney, J, Mehta, S, Mehta, D, Mehta, B, Messe, S, Miller, B, Milling, T, Moonis, M, Navaratnam, D, Okpala, M, Patel, N, Pettigrew, L, Phinney, T, Ramos-Estebanez, C, Rasmussen, J, Rodriguez, G, Rybinnik, I, Santiago, P, Sarraj, A, Savitz, S, Sawyer, R, Scandura, T, Schindler, J, Sen, S, Shang, T, Sharrief, A, Sila, C, Simpkins, A, Sundararajan, S, Talahma, M, Tayal, A, Thaler, D, Tirschwell, D, Torres, J, Vora, N, Warnack, W, Waters, M, Wilson, C, Xiong, W, Zweifler, R, Zanferrari, C., St Marys Development Trust, Servicio de Neurologia (SANTIAGO - Neurologie), Universidad del Desarrollo, Department of Neurology (Dep Neuro - BEIJING), Tiantan Hospital, Neurology department, Universidade de Coimbra [Coimbra], Department of Internal Medicine, University Hospital Basel [Basel], Laboratoire de Recherche Vasculaire Translationnelle (LVTS (UMR_S_1148 / U1148)), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Department of Neurological Sciences, Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], Department of Neurology, Seoul National University Hospital, Institute of Neurosciences and Psychology [Glasgow], University of Glasgow, Neurology Department, Ichilov Medical Center, CIC Brest, Université de Brest (UBO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hôpital de la Cavale Blanche, Yperzeele, Laetitia, NAVIGATE ESUS Investigators, and Selçuk Üniversitesi

Subjects
Stroke/etiology, Male, [SDV]Life Sciences [q-bio], Kaplan-Meier Estimate, 030204 cardiovascular system & hematology, Brain Ischemia, Brain ischemia, 0302 clinical medicine, DESIGN, Rivaroxaban, Hemorrhage/chemically induced, Secondary Prevention, Medicine, Factor Xa Inhibitors/adverse effects, Stroke, Rivaroxaban/adverse effects, ComputingMilieux_MISCELLANEOUS, 11 Medical and Health Sciences, Aspirin, Atrial fibrillation, General Medicine, FORAMEN OVALE CLOSURE, Middle Aged, TRIALS, Intracranial Embolism, SAFETY, Aged, Factor Xa Inhibitors, Female, Hemorrhage, Humans, Platelet Aggregation Inhibitors, Medicine (all), Cardiology, Foramen ovale closure, Platelet aggregation inhibitor, Settore MED/26 - Neurologia, Life Sciences & Biomedicine, medicine.drug, medicine.medical_specialty, Platelet Aggregation Inhibitors/adverse effects, ANTITHROMBOTIC THERAPY, Aspirin/adverse effects, WARFARIN, 03 medical and health sciences, Secondary Prevention/methods, Medicine, General & Internal, Internal medicine, Intracranial Embolism/drug therapy, General & Internal Medicine, NAVIGATE ESUS Investigators, METAANALYSIS, Science & Technology, CRYPTOGENIC STROKE, business.industry, Warfarin, medicine.disease, EFFICACY, ATRIAL-FIBRILLATION, Human medicine, business, Brain Ischemia/prevention & control, 030217 neurology & neurosurgery, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

WOS: 000434263000007, PubMed: 29766772, BACKGROUND Embolic strokes of undetermined source represent 20% of ischemic strokes and are associated with a high rate of recurrence. Anticoagulant treatment with rivaroxaban, an oral factor Xa inhibitor, may result in a lower risk of recurrent stroke than aspirin. METHODS We compared the efficacy and safety of rivaroxaban (at a daily dose of 15 mg) with aspirin (at a daily dose of 100 mg) for the prevention of recurrent stroke in patients with recent ischemic stroke that was presumed to be from cerebral embolism but without arterial stenosis, lacune, or an identified cardioembolic source. The primary efficacy outcome was the first recurrence of ischemic or hemorrhagic stroke or systemic embolism in a time-to-event analysis; the primary safety outcome was the rate of major bleeding. RESULTS A total of 7213 participants were enrolled at 459 sites; 3609 patients were randomly assigned to receive rivaroxaban and 3604 to receive aspirin. Patients had been followed for a median of 11 months when the trial was terminated early because of a lack of benefit with regard to stroke risk and because of bleeding associated with rivaroxaban. The primary efficacy outcome occurred in 172 patients in the rivaroxaban group (annualized rate, 5.1%) and in 160 in the aspirin group (annualized rate, 4.8%) (hazard ratio, 1.07; 95% confidence interval [CI], 0.87 to 1.33; P=0.52). Recurrent ischemic stroke occurred in 158 patients in the rivaroxaban group (annualized rate, 4.7%) and in 156 in the aspirin group (annualized rate, 4.7%). Major bleeding occurred in 62 patients in the rivaroxaban group (annualized rate, 1.8%) and in 23 in the aspirin group (annualized rate, 0.7%) (hazard ratio, 2.72; 95% CI, 1.68 to 4.39; P, BayerBayer AG; Janssen Research and Development, Supported by Bayer and Janssen Research and Development.

Published
2018

35. Safari: instrument design of the far-infrared imaging spectrometer for spica

Author

Jellema, W., Pastor, C., Naylor, D., Jackson, B., Sibthorpe, B., Roelfsema, P., Sodnik, Zoran, Cugny, Bruno, Karafolas, Nikos, Astronomy, and Kapteyn Astronomical Institute

Subjects
Zodiacal light, business.industry, Computer science, Reference design, Optical instrument, Imaging spectrometer, Spica, law.invention, Telescope, law, Systems architecture, Astronomical interferometer, Aerospace engineering, business
Abstract

The next great leap forward in space-based far-infrared astronomy will be made by the Japanese-led SPICA mission, which is anticipated to be launched late 2020's as the next large astrophysics mission of JAXA, in partnership with ESA and with key European contributions. Filling in the gap between JWST and ALMA, the SPICA mission will study the evolution of galaxies, stars and planetary systems. SPICA will utilize a deeply cooled 3m-class telescope, provided by European industry, to realize zodiacal background limited performance, high spatial resolution and large collecting area. Making full advantage of the deeply cooled telescope (

Published
2017

36. Far-infrared Herschel SPIRE spectroscopy of lensed starbursts reveals physical conditions of ionized gas

Author

Zhang, Zhi-Yu, primary, Ivison, R J, additional, George, R D, additional, Zhao, Yinghe, additional, Dunne, L, additional, Herrera-Camus, R, additional, Lewis, A J R, additional, Liu, Daizhong, additional, Naylor, D, additional, Oteo, Iván, additional, Riechers, D A, additional, Smail, Ian, additional, Yang, Chentao, additional, Eales, Stephen, additional, Hopwood, Ros, additional, Maddox, Steve, additional, Omont, Alain, additional, and van der Werf, Paul, additional

Published
2018
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38. SPICA—A Large Cryogenic Infrared Space Telescope: Unveiling the Obscured Universe

Author

Roelfsema, P. R., primary, Shibai, H., additional, Armus, L., additional, Arrazola, D., additional, Audard, M., additional, Audley, M. D., additional, Bradford, C.M., additional, Charles, I., additional, Dieleman, P., additional, Doi, Y., additional, Duband, L., additional, Eggens, M., additional, Evers, J., additional, Funaki, I., additional, Gao, J. R., additional, Giard, M., additional, di Giorgio, A., additional, Fernández, L. M. González, additional, Griffin, M., additional, Helmich, F. P., additional, Hijmering, R., additional, Huisman, R., additional, Ishihara, D., additional, Isobe, N., additional, Jackson, B., additional, Jacobs, H., additional, Jellema, W., additional, Kamp, I., additional, Kaneda, H., additional, Kawada, M., additional, Kemper, F., additional, Kerschbaum, F., additional, Khosropanah, P., additional, Kohno, K., additional, Kooijman, P. P., additional, Krause, O., additional, van der Kuur, J., additional, Kwon, J., additional, Laauwen, W. M., additional, de Lange, G., additional, Larsson, B., additional, van Loon, D., additional, Madden, S. C., additional, Matsuhara, H., additional, Najarro, F., additional, Nakagawa, T., additional, Naylor, D., additional, Ogawa, H., additional, Onaka, T., additional, Oyabu, S., additional, Poglitsch, A., additional, Reveret, V., additional, Rodriguez, L., additional, Spinoglio, L., additional, Sakon, I., additional, Sato, Y., additional, Shinozaki, K., additional, Shipman, R., additional, Sugita, H., additional, Suzuki, T., additional, van der Tak, F. F. S., additional, Redondo, J. Torres, additional, Wada, T., additional, Wang, S. Y., additional, Wafelbakker, C. K., additional, van Weers, H., additional, Withington, S., additional, Vandenbussche, B., additional, Yamada, T., additional, and Yamamura, I., additional

Published
2018
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39. Correcting the extended-source calibration for the Herschel-SPIRE Fourier-transform spectrometer

Author

Valtchanov, I, primary, Hopwood, R, additional, Bendo, G, additional, Benson, C, additional, Conversi, L, additional, Fulton, T, additional, Griffin, M J, additional, Joubaud, T, additional, Lim, T, additional, Lu, N, additional, Marchili, N, additional, Makiwa, G, additional, Meyer, R A, additional, Naylor, D A, additional, North, C, additional, Papageorgiou, A, additional, Pearson, C, additional, Polehampton, E T, additional, Scott, J, additional, Schulz, B, additional, Spencer, L D, additional, van der Wiel, M H D, additional, and Wu, R, additional

Published
2017
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40. ISO LWS measurement of the far-infrared spectrum of Saturn

Author

Davis, G, Griffin, M, Naylor, D, Oldham, P, Swinyard, B, Ade, P, Calcutt, S, Encrenaz, T, DeGraauw, T, Gautier, D, Irwin, P, Lellouch, E, Orton, G, Armand, C, Burgdorf, M, DiGiorgi, A, Ewart, D, Gry, C, King, K, Lim, T, Molinari, S, Price, M, Sidher, S, Smith, A, and Texier, D

Abstract

The spectrum of Saturn from 43 to 197 μm was measured with the ISO Long Wavelength Spectrometer (LWS) during the performance verification phase of the mission. The measurements were made using the LWS in grating mode, with spectral resolutions of 0.29 μm from 43 to 90 μm and 0.6 μm from 90 to 197 μm. The spectrum was compared with an atmospheric radiative-transfer model and four results were obtained: first, the slope of the measured continuum within each detector passband is in good agreement with the model; second, absorption features due to ammonia and phosphine were unambiguously detected, and all detected features were attributed to these two molecules; third, the ammonia absorption features agree reasonably well with the nominal model (based on Voyager IRIS measurements); and fourth, the phosphine absorption features disagree with the nominal model. Superior agreement with the measured spectrum was obtained with a modified PH3 profile in which the tropospheric mixing ratio was increased to 7 × 10-6 and the cutoff due to photodissociation was lowered to 300 mbar. These results are based on trial observations during performance verification of the LWS, and provide an indication of the results we expect to obtain when the spectrum of Saturn is measured comprehensively later in the mission.

Published
2016

43. Calibration ofHerschelSPIRE FTS observations at different spectral resolutions

Author

Marchili, N., primary, Hopwood, R., additional, Fulton, T., additional, Polehampton, E. T., additional, Valtchanov, I., additional, Zaretski, J., additional, Naylor, D. A., additional, Griffin, M. J., additional, Imhof, P., additional, Lim, T., additional, Lu, N., additional, Makiwa, G., additional, Pearson, C., additional, and Spencer, L., additional

Published
2016
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44. The Herschel/SPIRE Spectrometer Useful Scripts

Author

Polehampton, E., Hopwood, R., Valtchanov, I., Lu, N., MARCHILI, Nicola, Naylor, D., van der Wiel, M., Fulton, T., Taylor, A. R., and Rosolowsky, E.

Subjects
Astrophysics::Instrumentation and Methods for Astrophysics, Astrophysics::Cosmology and Extragalactic Astrophysics, Astrophysics::Galaxy Astrophysics
Abstract

In most cases, the Standard Product Generation (SPG) processing pipelines for the Herschel SPIRE Fourier Transform Spectrometer (FTS) produce well-calibrated spectra of high quality. However, some Astronomical sources, such as those with a faint continuum, require additional processing to achieve more meaningful spectra. In consultation with the astronomical community, a set of scripts were developed to assist in the post-pipeline analysis of the spectra.

Published
2015

46. The data processing pipeline for theHerschelSPIRE Fourier Transform Spectrometer

Author

Fulton, T., primary, Naylor, D. A., additional, Polehampton, E. T., additional, Valtchanov, I., additional, Hopwood, R., additional, Lu, N., additional, Baluteau, J.-P., additional, Mainetti, G., additional, Pearson, C., additional, Papageorgiou, A., additional, Guest, S., additional, Zhang, L., additional, Imhof, P., additional, Swinyard, B. M., additional, Griffin, M. J., additional, and Lim, T. L., additional

Published
2016
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48. Correcting the extended-source calibration for the Herschel-SPIRE Fourier-transform spectrometer.

Author

Valtchanov, I., Hopwood, R., Bendo, G., Benson, C., Conversi, L., Fulton, T., Griffin, M. J., Joubaud, T., Lim, T., Lu, N., Marchili, N., Makiwa, G., Meyer, R. A., Naylor, D. A., North, C., Papageorgiou, A., Pearson, C., Polehampton, E. T., Scott, J., and Schulz, B.

Subjects
FOURIER transform spectrometers, ASTRONOMICAL photometry, FRAUNHOFER region (Electromagnetism), SPACE vehicles, SPECTROGRAPHS
Abstract

We describe an update to the Herschel-Spectral and Photometric Imaging Receiver (SPIRE) Fourier-transform spectrometer (FTS) calibration for extended sources, which incorporates a correction for the frequency-dependent far-field feedhorn efficiency, ηff. This significant correction affects all FTS extended-source calibrated spectra in sparse or mapping mode, regardless of the spectral resolution. Line fluxes and continuum levels are underestimated by factors of 1.3-2 in thespectrometer long wavelength band (447-1018 GHz; 671-294 μm) and 1.4-1.5 in the spectrometer short wavelength band (944-1568 GHz; 318-191 μm). The correctionwas implemented in the FTS pipeline version 14.1 and has also been described in the SPIRE Handbook since 2017 February. Studies based on extended-source calibrated spectra produced prior to this pipeline version should be critically reconsidered using the current products available in the Herschel Science Archive. Once the extended-source calibrated spectra are corrected for ηff, the synthetic photometry and the broad-band intensities from SPIRE photometer maps agree within 2-4 per cent - similar levels to the comparison of point-source calibrated spectra and photometry from point-source calibrated maps. The two calibration schemes for the FTS are now self-consistent: the conversion between the corrected extended-source and point-source calibrated spectra can be achieved with the beam solid angle and a gain correction that accounts for the diffraction loss. [ABSTRACT FROM AUTHOR]

Published
2018
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50. Systematic characterization of the Herschel SPIRE Fourier Transform Spectrometer★

Author

Hopwood, R., primary, Polehampton, E. T., additional, Valtchanov, I., additional, Swinyard, B. M., additional, Fulton, T., additional, Lu, N., additional, Marchili, N., additional, van der Wiel, M. H. D., additional, Benielli, D., additional, Imhof, P., additional, Baluteau, J.-P., additional, Pearson, C., additional, Clements, D. L., additional, Griffin, M. J., additional, Lim, T. L., additional, Makiwa, G., additional, Naylor, D. A., additional, Noble, G., additional, Puga, E., additional, and Spencer, L. D., additional

Published
2015
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