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Your search keyword '"Musabeyezu, Emmanuel"' showing total 16 results
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16 results on '"Musabeyezu, Emmanuel"'

1. Hepatocellular carcinoma: measures to improve the outlook in sub-Saharan Africa

Author

Spearman, C Wendy, Dusheiko, Geoffrey, Jonas, Eduard, Abdo, Abdelmounem, Afihene, Mary, Cunha, Lina, Desalegn, Hailemichael, Kassianides, Chris, Katsidzira, Leolin, Kramvis, Anna, Lam, Philip, Lesi, Olufunmilayo A, Micah, Eileen A, Musabeyezu, Emmanuel, Ndow, Gibril, Nnabuchi, Chidi V, Ocama, Ponsiano, Okeke, Edith, Rwegasha, John, Shewaye, Abate B, Some, Fatuma F, Tzeuton, Christian, and Sonderup, Mark W

Published
2022
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2. Safety and efficacy of sofosbuvir–velpatasvir–voxilaprevir for re-treatment of chronic hepatitis C virus infection in patients with previous direct-acting antiviral treatment failure in Rwanda (SHARED-3): a single-arm trial

Author

Gupta, Neil, Manirambona, Linda, Shumbusho, Fabienne, Kabihizi, Jules, Murangwa, Anthere, Serumondo, Janvier, Makuza, Jean Damascene, Nsanzimana, Sabin, Muvunyi, Claude Mambo, Mukabatsinda, Constance, Musabeyezu, Emmanuel, Camus, Gregory, Grant, Philip M, and Kateera, Fredrick

Published
2022
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4. Hepatitis B in sub-Saharan Africa: strategies to achieve the 2030 elimination targets

Author

Spearman, C Wendy, Afihene, Mary, Ally, Reidwaan, Apica, Betty, Awuku, Yaw, Cunha, Lina, Dusheiko, Geoffrey, Gogela, Neliswa, Kassianides, Chris, Kew, Michael, Lam, Philip, Lesi, Olufunmilayo, Lohouès-Kouacou, Marie-Jeanne, Mbaye, Papa Saliou, Musabeyezu, Emmanuel, Musau, Betty, Ojo, Olusegun, Rwegasha, John, Scholz, Barbara, Shewaye, Abate B, Tzeuton, Christian, and Sonderup, Mark W

Published
2017
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5. Hepatitis C in sub-Saharan Africa: the current status and recommendations for achieving elimination by 2030

Author

Sonderup, Mark W, Afihene, Mary, Ally, Reidwaan, Apica, Betty, Awuku, Yaw, Cunha, Lina, Dusheiko, Geoffrey, Gogela, Neliswa, Lohouès-Kouacou, Marie-Jeanne, Lam, Phillip, Lesi, Olufunmilayo, Mbaye, Papa Saliou, Musabeyezu, Emmanuel, Musau, Betty, Ojo, Olesegun, Rwegasha, John, Scholz, Barbara, Shewaye, Abate B, Tzeuton, Christian, Kassianides, Chris, and Spearman, C Wendy

Published
2017
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7. Risk factors for difficult‐to‐treat hepatitis C virus genotype 4r in Rwanda and implications for elimination in sub‐Saharan Africa

Author

Shumbusho, Fabienne, primary, Liu, Anne F., additional, Kateera, Fredrick, additional, Kabahizi, Jules, additional, Nsanzaimana, Sabin, additional, Serumondo, Janvier, additional, Damascene Makuza, Jean, additional, Grant, Philip M., additional, Musabeyezu, Emmanuel, additional, Muvunyi, Claude, additional, and Gupta, Neil, additional

Published
2021
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8. Improved quality of life following direct‐acting antiviral treatment for chronic hepatitis C infection in Rwanda: Results from a clinical trial in sub‐Saharan Africa (the SHARED study)

Author

Van Nuil, Jennifer Ilo, primary, Umutesi, Grace, additional, Shumbusho, Fabienne, additional, Kateera, Frederick, additional, Dushimimana, Jean de Dieu, additional, Muvunyi, Claude Mambo, additional, Musabeyezu, Emmanuel, additional, Mukabatsinda, Constance, additional, Ntirenganya, Cyprien, additional, Kabahizi, Jules, additional, Serumondo, Janvier, additional, Makuza, Jean Damascene, additional, Nsanzimana, Sabin, additional, Grant, Philip, additional, and Gupta, Neil, additional

Published
2020
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9. Care seeking and treatment for hepatitis C infection in Rwanda: A qualitative study of patient experiences

Author

Van Nuil, Jennifer Ilo, primary, Shumbusho, Fabienne, additional, Kateera, Fredrick, additional, Mukuralinda, Alain, additional, Kabahizi, Jules, additional, Muvunyi, Claude Mambo, additional, Musabeyezu, Emmanuel, additional, Mukabatsinda, Constance, additional, Mbituyumuremi, Aimable, additional, Nsanzimana, Sabin, additional, Mukerjee, Joia, additional, and Gupta, Neil, additional

Published
2020
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10. Safety and Efficacy of Limited Laboratory Monitoring for Hepatitis C Treatment: A Blinded Clinical Trial in Rwanda

Author

Grant, Philip, primary, Shumbusho, Fabienne, additional, Van Nuil, Jennifer Ilo, additional, Kateera, Fredrick, additional, Mukherjee, Joia, additional, Kabahizi, Jules, additional, Ntaganda, Fabien, additional, Nsanzimana, Sabin, additional, Mbituyumuremyi, Aimable, additional, Damascene, Makuza Jean, additional, Muvunyi, Claude Mambo, additional, Mukabatsinda, Constance, additional, Musabeyezu, Emmanuel, additional, Ntirenganya, Cyprien, additional, and Gupta, Neil, additional

Published
2020
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12. Improved quality of life following direct‐acting antiviral treatment for chronic hepatitis C infection in Rwanda: Results from a clinical trial in sub‐Saharan Africa (the SHARED study).

Author

Van Nuil, Jennifer Ilo, Umutesi, Grace, Shumbusho, Fabienne, Kateera, Frederick, Dushimimana, Jean de Dieu, Muvunyi, Claude Mambo, Musabeyezu, Emmanuel, Mukabatsinda, Constance, Ntirenganya, Cyprien, Kabahizi, Jules, Serumondo, Janvier, Makuza, Jean Damascene, Nsanzimana, Sabin, Grant, Philip, and Gupta, Neil

Subjects
CHRONIC hepatitis C, CHRONIC hepatitis B, HEPATITIS C, QUALITY of life, CLINICAL trials, HEPATITIS C virus, TREATMENT effectiveness
Abstract

Around 71 million people are living with chronic hepatitis C virus (HCV) infection, with approximately 14% residing in sub‐Saharan Africa. Direct‐acting antiviral (DAA) therapies offer clear benefits for liver‐related morbidity and mortality, and data from high‐income settings suggest that DAA treatments also provide significant benefits in terms of health‐related quality of life (HRQL). In this study, we assessed the effect of DAA treatment on HRQL for individuals treated for HCV in a clinical trial in Rwanda. We assessed the HRQL of participants using an 83‐question composite survey at Day 0 ('baseline') and Week 24 ('endpoint'). Data were analysed in R. A total of 296 participants were included in this analysis. Their ages ranged from 19 to 90, and 184 (62.2%) were female. There were significant improvements from baseline to endpoint median scores for all physical and mental quality of life sub‐scales. Additionally, a reduction—before and after treatment—in the proportion of those classified as depressed and needing social support was statistically significant (both P <.001). Economic productivity increased after treatment (P <.001), and households classified as food secure increased from baseline to endpoint (P <.001). These results demonstrate that Rwandans with chronic HCV infection experience both clinical and HRQL benefits, including household‐level benefits like substantial gains in workforce stability, economic productivity, and poverty alleviation, from DAA treatment. A stronger demonstration of accurate and broader household‐level benefits achieved through treatment of HCV with DAAs will help financing and investment for HCV in resource‐constrained settings become an urgent priority. [ABSTRACT FROM AUTHOR]

Published
2021
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13. “Waiting for DAAs”: A retrospective chart review of patients with untreated hepatitis C in Rwanda

Author

Gupta, Neil, primary, Kabahizi, Jules, additional, Mukabatsinda, Constance, additional, Walker, Timothy David, additional, Musabeyezu, Emmanuel, additional, Kiromera, Athanase, additional, Van Nuil, Jennifer Ilo, additional, Steiner, Kevin, additional, Mukherjee, Joia, additional, Nsanzimana, Sabin, additional, and Mbituyumuremyi, Aimable, additional

Published
2017
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16. Association of Abnormal Liver Function Parameters with HIV Serostatus and CD4 Count in Antiretroviral-Naive Rwandan Women

Author

Dusingize, Jean Claude, primary, Hoover, Donald R., additional, Shi, Qiuhu, additional, Mutimura, Eugene, additional, Rudakemwa, Emmanuel, additional, Ndacyayisenga, Victorien, additional, Gakindi, Léonard, additional, Mulvihill, Michael, additional, Sinayobye, Jean D'Amour, additional, Musabeyezu, Emmanuel, additional, and Anastos, Kathryn, additional

Published
2015
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