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Although commendable progress for combating malaria in endemic areas has been achieved and a dozen countries have been declared malaria-free since 2000 (1), increasing international travel has led to a [...]

BACKGROUND: To assist clinicians with identifying children at risk of severe outcomes, we assessed the association between laboratory findings and severe outcomes among severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected children and determined if SARS-CoV-2 test result status modified the associations. METHODS: We conducted a cross-sectional analysis of participants tested for SARS-CoV-2 infection in 41 pediatric emergency departments in 10 countries. Participants were hospitalized, had laboratory testing performed, and completed 14-day follow-up. The primary objective was to assess the associations between laboratory findings and severe outcomes. The secondary objective was to determine if the SARS-CoV-2 test result modified the associations. RESULTS: We included 1817 participants; 522 (28.7%) SARS-CoV-2 test-positive and 1295 (71.3%) test-negative. Seventy-five (14.4%) test-positive and 174 (13.4%) test-negative children experienced severe outcomes. In regression analysis, we found that among SARS-CoV-2-positive children, procalcitonin ≥0.5 ng/mL (adjusted odds ratio [aOR], 9.14; 95% CI, 2.90-28.80), ferritin >500 ng/mL (aOR, 7.95; 95% CI, 1.89-33.44), D-dimer ≥1500 ng/mL (aOR, 4.57; 95% CI, 1.12-18.68), serum glucose ≥120 mg/dL (aOR, 2.01; 95% CI, 1.06-3.81), lymphocyte count

Dengue virus (DENV) is not endemic in the continental United States (1); most cases occur among travelers to DENV-endemic areas (2). In Florida, USA, DENV infections are primarily reported among [...]

Dengue virus serotype 3 (DENV-3) consists of 5 distinct genotypes (I-V). Genotype III (GIII) is the most widespread and was associated with large outbreaks in Asia, Africa, and the Americas [...]

As the Chinese economy shifts from factor-driven to innovation-driven growth, Chinese firms are increasingly lacking highly skilled talents. In this context, attracting high-skill returnees might represent an effective strategy to access knowledge. In this paper, we investigate the relationship between high-skill returnees and innovation of Chinese publicly listed firms. We construct a unique dataset of 2,499 firms over the period 2002–16 by combining three different data sources (i.e. Chinese Research Data Services Platform, China Stock Market & Accounting Research Database, and LinkedIn). Our results show that different typologies of returnees (employees, technologists, and managers) with different experiences abroad (work vs study) may bring back different skills and impact differently on firm innovation. Our main findings show that (1) returnee employees and technologists are positively associated with firm's patenting; (2) returnees' overseas work experience matters more than study experience; and (3) the positive role of returnees is subject to contingencies related to firm characteristics such as ownership, location, and size. [ABSTRACT FROM AUTHOR]

Zika virus is a flavivirus that was first isolated in 1947 from a rhesus macaque in the Zika Forest in Uganda. Zika virus is primarily transmitted to humans by infected [...]

This article investigates the role of local external linkages in supporting regional industry entry in new activities, by specifically considering the role of foreign multinational enterprises (MNEs). Theoretically, we construct an original conceptual framework encompassing different potential trajectories of regional diversification based on the presence of MNEs. Empirically, we focus on the case of 279 Chinese prefectures over 1998–2007 and our results suggest that the presence of MNEs is associated with industry entry in unrelated and complex industries, supporting the idea that regional external linkages can activate processes of diversification that modify the technological and industrial portfolio of local economies. [ABSTRACT FROM AUTHOR]

This article explores how the components of the technological regime affect catching-up and leadership change in green technologies in countries that are leaders and successful latecomers. We look at the extent to which technological opportunity, cumulativeness, originality and complexity of the knowledge base, and the maturity of technology contribute to the growth of patenting in green technologies. We test the relationships using USPTO patent data in green technologies over a 40-year time span (1975–2015), distinguishing two periods (1975–1999 and 2000–2015) and controlling for country-specific variables. Our results show that opportunity, complexity, originality, and maturity of the technology are positively associated with countries' growth of patenting in green technologies, while cumulativeness has a negative effect, but only in the second period (2000–2015). The stock of knowledge has a positive effect in the first period and a negative effect in the second one. Furthermore, we find confirmation that the process of growth in green patenting has been remarkable in successful latecomer countries (i.e. South Korea, Taiwan, and China). [ABSTRACT FROM AUTHOR]

Different strands of literature have provided important insights into the economic effects of high-skilled migration. Evolutionary economic approaches have provided robust evidence and theories to explain how innovation unfolds in regions. However, with few exceptions they have been silent with regard to the role of migration in this process. This paper, while building on the insights of the above streams of literature, will elaborate a conceptual framework which applies evolutionary economic geography concepts to explore the link between migration, knowledge diffusion and regional diversification. By bringing together all the above arguments, this paper brings evolutionary economic geography (EEG) into an unchartered terrain, one where regional innovation meets migration studies. By engaging in these debates, EEG can prove its interpretative power and provide further insights into the drivers of regional economic dynamics and innovation. [ABSTRACT FROM AUTHOR]

We report a dengue outbreak in Key Largo, Florida, USA, from February through August 2020, during the COVID-19 pandemic. Successful community engagement resulted in 61% of case-patients self-reporting. We also describe COVID-19 pandemic effects on the dengue outbreak investigation and the need to increase clinician awareness of dengue testing recommendations. [ABSTRACT FROM AUTHOR]