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Your search keyword '"Miyashita, K."' showing total 465 results
Start Over Author "Miyashita, K." Publication Year Range Last 10 years
465 results on '"Miyashita, K."'

2. The energy spectrum of cosmic rays measured by the Telescope Array using 10 years of fluorescence detector data

Author

Abbasi, R.U., Abe, Y., Abu-Zayyad, T., Allen, M., Arai, Y., Arimura, R., Barcikowski, E., Belz, J.W., Bergman, D.R., Blake, S.A., Buckland, I., Cheon, B.G., Chikawa, M., Fedynitch, A., Fujii, T., Fujisue, K., Fujita, K., Fujiwara, R., Fukushima, M., Furlich, G., Gerber, Z., Globus, N., Hanlon, W., Hayashida, N., He, H., Hibi, R., Hibino, K., Higuchi, R., Honda, K., Ikeda, D., Inoue, N., Ishii, T., Ito, H., Ivanov, D., Iwasaki, A., Jeong, H.M., Jeong, S., Jui, C.C.H., Kadota, K., Kakimoto, F., Kalashev, O., Kasahara, K., Kasami, S., Kawakami, S., Kawata, K., Kharuk, I., Kido, E., Kim, H.B., Kim, J.H., Kim, S.W., Kimura, Y., Komae, I., Komori, K., Kusumori, Y., Kuznetsov, M., Kwon, Y.J., Lee, K.H., Lee, M.J., Lubsandorzhiev, B., Lundquist, J.P., Matsuyama, T., Matthews, J.A., Matthews, J.N., Mayta, R., Miyashita, K., Mizuno, K., Mori, M., Murakami, M., Myers, I., Nagataki, S., Nakai, K., Nakamura, T., Nishio, E., Nonaka, T., Ogio, S., Ohoka, H., Okazaki, N., Oku, Y., Okuda, T., Omura, Y., Onishi, M., Ono, M., Oshima, A., Oshima, H., Ozawa, S., Park, I.H., Park, K.Y., Potts, M., Pshirkov, M.S., Remington, J., Rodriguez, D.C., Rott, C., Rubtsov, G.I., Ryu, D., Sagawa, H., Saito, R., Sakaki, N., Sako, T., Sakurai, N., Sato, D., Sato, K., Sato, S., Sekino, K., Shah, P.D., Shibata, N., Shibata, T., Shikita, J., Shimodaira, H., Shin, B.K., Shin, H.S., Shinto, D., Smith, J.D., Sokolsky, P., Stokes, B.T., Stroman, T.A., Takagi, Y., Takahashi, K., Takamura, M., Takeda, M., Takeishi, R., Taketa, A., Takita, M., Tameda, Y., Tanaka, K., Tanaka, M., Thomas, S.B., Thomson, G.B., Tinyakov, P., Tkachev, I., Tokuno, H., Tomida, T., Troitsky, S., Tsuda, R., Tsunesada, Y., Udo, S., Urban, F., Vaiman, I.A., Warren, D., Wong, T., Yamazaki, K., Yashiro, K., Yoshida, F., Zhezher, Y., and Zundel, Z.

Published
2023
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4. Field Measurement of Gas Dispersion in the Atsugi Area

Author

Sasaki, R., Miyashita, K., Yoshie, R., di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Ricciardelli, Francesco, editor, and Avossa, Alberto Maria, editor

Published
2019
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5. Does the pre-procedural pathophysiological pattern impact post-procedural hemodynamic outcomes and vessel prognosis in multivessel coronary artery disease?

Author

Kageyama, S, primary, Tsai, T, additional, Miyashita, K, additional, Reiber, J H C, additional, Tu, S, additional, Zaman, A, additional, Sabate, M, additional, Mollmann, H, additional, Sharif, F, additional, Lemoine, J, additional, Wlodarczak, A, additional, Onuma, Y, additional, and Serruys, P W, additional

Published
2023
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6. Coexistence of primary colorectal follicular lymphoma and multiple myeloma: a case report

Author

Saito M, Miyashita K, Miura Y, Ogasawara R, Kanaya M, Izumiyama K, Mori A, Kondo T, Tanaka M, Morioka M, and Tanaka S

Subjects
Follicular lymphoma, Colon, Multiple myeloma, Coexistence, Treatment, Medicine (General), R5-920
Abstract

Makoto Saito,1 Kencho Miyashita,2 Yosuke Miura,3 Reiki Ogasawara,1 Minoru Kanaya,1 Koh Izumiyama,1 Akio Mori,1 Takeshi Kondo,1 Masanori Tanaka,1 Masanobu Morioka,1 Shinya Tanaka4 1Department of Internal Medicine and Hematology, Aiiku Hospital, Sapporo, Japan; 2Department of Gastroenterology, Aiiku Hospital, Sapporo, Japan; 3Department of Internal Medicine, Megumino Hospital, Eniwa, Japan; 4Department of Cancer Pathology, Hokkaido University Graduate School of Medicine, Sapporo, Japan Abstract: Colorectal follicular lymphoma (FL) occurs less frequently than duodenal-type FL, which is an established entity, and primary multiple FL only involving the colon is rare. Furthermore, the coexistence of lymphoma and multiple myeloma (MM) within the same patient is rare and the current study reports such a case. The patient was an asymptomatic 62-year-old man. He underwent colonoscopy screening, which revealed at least five polypoid tumors from the cecum to the rectum. Biopsy samples stained positive for CD20 and B-cell lymphoma 2 (BCL2) but stained negative for CD10, and fluorescence in situ hybridization analysis identified IGH/BCL2 in 95.2% of the tumor cells. Based on these findings, the patient was diagnosed with FL. On the bone marrow aspirate, the plasma cell count was 30% of all nucleated cells. Bence-Jones κ-type protein was detected by protein electrophoresis in serum and urine. The serum-free light chain κ/λ level was significantly elevated (484.3). Thus, the patient was also diagnosed with MM. Both FL and MM were targeted therapeutically; rituximab and bendamustine were effective for FL, and lenalidomide and low-dose dexamethasone were effective for MM. The patient was treated for 3 years and 7 months and, until now, was off-treatment for 4 years without rapid progression of the two malignancies. Although both diseases are still present, the patient has maintained stable disease. Our findings suggest that lymphoma and MM should be targeted separately as independent hematological malignancies when they occur concurrently. Keywords: follicular lymphoma, colon, multiple myeloma, coexistence, treatment

Published
2018

12. P-152 Observational Cohort Study of 1st line Bevacizumab Combined with Chemotherapy in Metastatic Colorectal Cancer (HGCSG0802): Sub-group Analysis by the Glasgow Prognostic Score (GPS)

Author

Miyagishima, T., Yuki, S., Nakatsumi, H., Kawamoto, Y., Muranaka, T., Sawada, K., Kobayashi, Y., Sasaki, T., Nakamura, M., Sato, A., Iwanaga, I., Tateyama, M., Hatanaka, K., Eto, K., Okuda, H., Muto, O., Abe, M., Oba, A., Kato, S., Miyashita, K., Sakata, Y., and Komatsu, Y.

Published
2016
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13. P-98 HGCSG1902: Multicenter, prospective, observational study for cases with dysgeusia caused by chemotherapy for gastrointestinal cancer

Author

Ando, T., primary, Ito, K., additional, Yuki, S., additional, Saito, R., additional, Nakano, S., additional, Nakatsumi, H., additional, Kawamoto, Y., additional, Dazai, M., additional, Miyashita, K., additional, Hatanaka, K., additional, Harada, K., additional, Miyagishima, T., additional, Hisai, H., additional, Ishiguro, A., additional, Ueda, A., additional, Kato, T., additional, Sasaki, T., additional, Shindo, Y., additional, Yokota, I., additional, Takagi, R., additional, Sakata, Y., additional, and Komatsu, Y., additional

Published
2020
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21. Survival Benefit of Corticosteroid and Intravenous Cyclophosphamide Therapy in Acute Exacerbation of Idiopathic Pulmonary Fibrosis: A Propensity Score-Matched Analysis

Author

Hozumi, H., primary, Hasegawa, H., additional, Miyashita, K., additional, Yasui, H., additional, Suzuki, Y., additional, Kono, M., additional, Karayama, M., additional, Furuhashi, K., additional, Hashimoto, D., additional, Enomoto, N., additional, Fujisawa, T., additional, Inui, N., additional, Nakamura, Y., additional, Yokomura, K., additional, Nakamura, H., additional, and Suda, T., additional

Published
2019
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23. Effects of Polymer Encapsulated Glial Cell Line-Derived Neurotrophic Factor Secreting Cells on Odontoblast-like Cell Survival

Author

Wahlberg Lu, Miyashita K, Chiaki Kitamura, Takahiko Morotomi, Saito N, Ayako Washio, Tatsuji Nishihara, and Emerich Df

Subjects
biology, urogenital system, Chemistry, Cell, In vitro, Cell biology, Odontoblast, medicine.anatomical_structure, nervous system, In vivo, Neurotrophic factors, Glial cell line-derived neurotrophic factor, biology.protein, medicine, Pulp (tooth), Wound healing
Abstract

Objective: Cells that are encapsulated into immunoprotective and implantable devices provide a means of enabling targeted, longterm, continuous, de novo synthesized delivery of very high levels of therapeutic molecules. In this study, we examined effects of polymer encapsulated glial cell line-derived neurotrophic factor (GDNF) secreting ARPE-19 cells on the in vitro viability of odontoblast-like cells (KN-3 cells) under normally lethal starvation conditions. Materials and methods: Devices (polymeric hollow fibers) were loaded with either GDNF-secreting ARPE-19 cells (GDNF-device) or non-modified ARPE-19 cells (ARPE-control device). KN-3 cell survival and function was quantified under starvation conditions when the cells were co-cultured with either control or GDNF devices. We further examined the specificity of GDNF by neutralizing the activity of GDNF with the soluble GDNF receptor (GFRα-1). Results: When KN-3 cells were co-cultured with either device under starvation, the cells exhibited a concentration gradient-dependent enhancement of survival in the area immediately surrounding the device. Similar survival benefits occurred when KN-3 cells were cultured in media previously used to maintain the cells encapsulated in the device. Because ARPE-19 cells also normally secrete low levels of VEGF, the maintenance medium from each device group was pretreated with soluble Flt-1 or soluble GFRα-1 to neutralize VEGF or GDNF. The survival of KN-3 cells was suppressed when cultured in VEGF-neutralized medium from ARPE-control devices, but not in that from GDNF-devices. In contrast, when GDNF was neutralized with soluble GFRα-1, the survival of KN-3 cells was intensely suppressed. Conclusion: These results suggest that GDNF delivered from encapsulated cells can augment the survival of odontoblast-like cells, and that the delivery of growth factors by encapsulated cells may be useful for enhancing pulp wound healing and regeneration. These data also pave the way for additional in vivo studies to determine the utility of this approach in regenerative endodontics.

Published
2017

28. NORTH/HGCSG1003: A phase II study evaluating the safety and efficacy of FOLFOX as adjuvant chemotherapy for patients with stage III colon cancer: Comparison with medical oncologists and surgeons

Author

Yuki, S., primary, Komatsu, Y., additional, Kawamoto, Y., additional, Nakatsumi, H., additional, Takahashi, N., additional, Shichinohe, T., additional, Okuda, H., additional, Ishiguro, A., additional, Harada, K., additional, Iwanaga, I., additional, Hatanaka, K., additional, Oomori, K., additional, Nakamura, M., additional, Senmaru, N., additional, Iwai, K., additional, Koike, M., additional, Shinohara, T., additional, Miyashita, K., additional, Ito, Y.M., additional, Taketomi, A., additional, Hirano, S., additional, and Sakamoto, N., additional

Published
2018
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39. 190P Observational cohort study of 1st line bevacizumab combined with chemotherapy in metastatic colorectal cancer (HGCSG0802): Sub-group analysis by the Glasgow Prognostic Score (GPS)

Author

Sasaki, T., primary, Yuki, S., additional, Kawamoto, Y., additional, Harada, K., additional, Meguro, T., additional, Miyagishima, T., additional, Nakamura, M., additional, Sato, A., additional, Iwanaga, I., additional, Tateyama, M., additional, Hatanaka, K., additional, Eto, K., additional, Okuda, H., additional, Muto, O., additional, Abe, M., additional, Oba, A., additional, Kato, S., additional, Miyashita, K., additional, Sakata, Y., additional, and Komatsu, Y., additional

Published
2016
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43. 172P Updated analysis: observational cohort study of 1st line bevacizumab combined with chemotherapy in metastatic colorectal cancer (HGCSG0802): Comparison of infusional FU/oxaliplatin (OX) + BV and oral FU/OX + BV

Author

Komatsu, Y., primary, Yuki, S., additional, Nakatsumi, H., additional, Sawada, K., additional, Hatanaka, K., additional, Kato, T., additional, Meguro, T., additional, Nakamura, M., additional, Iwanaga, I., additional, Uebayashi, M., additional, Tateyama, M., additional, Eto, K., additional, Kudo, M., additional, Kato, K., additional, Okuda, H., additional, Sogabe, S., additional, Miyagishima, T., additional, Miyashita, K., additional, Sakamoto, N., additional, and Sakata, Y., additional

Published
2015
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44. 2092 Updated analysis: Observational cohort study of 1st line bevacizumab combined with chemotherapy in metastatic colorectal cancer (HGCSG0802): Comparison of infusional FU/oxaliplatin(OX)+BV and oral FU/OX+BV

Author

Nakatsumi, H., primary, Yuki, S., additional, Kawamoto, Y., additional, Muranaka, T., additional, Hatanaka, K., additional, Kato, T., additional, Meguro, T., additional, Nakamura, M., additional, Iwanaga, I., additional, Uebayashi, M., additional, Tateyama, M., additional, Eto, K., additional, Kudo, M., additional, Kato, S., additional, Okuda, H., additional, Sogabe, S., additional, Miyashita, K., additional, Sakata, Y., additional, Sakamoto, N., additional, and Komatsu, Y., additional

Published
2015
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45. P-223 - NORTH/HGCSG1003: A phase II study evaluating the safety and efficacy of FOLFOX as adjuvant chemotherapy for patients with stage III colon cancer: Comparison with medical oncologists and surgeons

Author

Yuki, S., Komatsu, Y., Kawamoto, Y., Nakatsumi, H., Takahashi, N., Shichinohe, T., Okuda, H., Ishiguro, A., Harada, K., Iwanaga, I., Hatanaka, K., Oomori, K., Nakamura, M., Senmaru, N., Iwai, K., Koike, M., Shinohara, T., Miyashita, K., Ito, Y.M., Taketomi, A., Hirano, S., and Sakamoto, N.

Published
2018
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46. Optimization of essential oil and fucoxanthin extraction from Sargassum binderi by Supercritical Carbon Dioxide (SC-CO2) extraction with ethanol as co-solvent Using Response Surface Methodology (RSM).

Author

Jaswir, I., Noviendri, D., Taher, M., Mohamed, F., Salleh, H. M., Octavianti, F., Lestari, W., Hendri, R., Abdullah, A., Miyashita, K., and Hasna, A.

Subjects
SUPERCRITICAL carbon dioxide, RESPONSE surfaces (Statistics), ESSENTIAL oils, SARGASSUM, SOLVENT extraction, REGRESSION analysis
Abstract

Supercritical carbon dioxide (SC-CO2) extraction of fucoxanthin is more advantageous over conventional solvent extraction as it is less toxic, less hazardous to the environment and preserves the bioactivity of fucoxanthin. A face-centered central composite design (FCCCD) based on response surface methodology (RSM) was employed for SC-CO2 extraction of oils and fucoxanthin from the brown seaweed Sargassum binderi, with ethanol as a co-solvent. Three independent parameters namely, extraction temperature (A: 40, 50, 60°C), pressure (B: 2900, 3625, 4350 psig and particle size (C: 90, 500 and 1000 µm) were investigated to optimize extraction oil yields (EOY) and fucoxanthin yields (FY). A regression model was developed, tested for quality of fit (R²) and expressed in the form of 3D response surface curve and 2D contour. The optimum extraction conditions were obtained at extraction temperature (A) 50°C, pressure (B) 3625 psig and particle size (C) 500 µm. Under these conditions, optimal EOY and FY were 10.04 mg/g and 3188.99 µg/g, respectively. The difference between the lowest and the highest response in EOY and FY were 5.44 - 10.04 mg/g and 2109.10 - 3188.90 µg/g, respectively. The lowest yields were identified at 60°C, 2900 psig and 1000 µm. The regression models generated showing interactions between the variables and EOY and FY response were significant as tested by ANOVA (p < 0.0005 and p < 0.0007, respectively) with high R² values (0.9848 and 0.9829, respectively). Interactions between the parameters had a strong synergistic effect on EOY and FY values, as indicated by the 3D response surface curve and 2D contour. The experimental results matched the predicted results closely. This indicated the suitability of the models developed and the success of FCCCD under RSM in optimizing the S. binderi extraction conditions. [ABSTRACT FROM AUTHOR]

Published
2017

47. PP.23.08

Author

Miyai, N., primary, Aoji, Y., additional, Morishita, M., additional, Uchikawa, Y., additional, Utsumi, M., additional, Miyashita, K., additional, Takeda, S., additional, and Arita, M., additional

Published
2015
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48. P-249 Safety analysis of FOLFOX as adjuvant chemotherapy for stage III colon cancer in phase II study (NORTH/HGCSG1003) - an analysis of surgeons vs oncologists

Author

Iwanaga, I., primary, Yuki, S., additional, Fukushima, H., additional, Takahashi, N., additional, Shichinohe, T., additional, Kusumi, T., additional, Nakamura, F., additional, Sogabe, S., additional, Hatanaka, K., additional, Oomori, K., additional, Misawa, K., additional, Senmaru, N., additional, Iwai, K., additional, Shinohara, T., additional, Koike, M., additional, Miyashita, K., additional, Amano, T., additional, Ito, Y.M., additional, Sakamoto, N., additional, Taketomi, A., additional, Hirano, S., additional, and Komatsu, Y., additional

Published
2015
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49. PP.38.23

Author

Aoji, Y., primary, Miyai, N., additional, Morishita, M., additional, Uchikawa, Y., additional, Utsumi, M., additional, Miyashita, K., additional, Takeda, S., additional, and Arita, M., additional

Published
2015
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