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1. A MALDI-TOF-MS Approach for Mammalian, Human, and Formula Milk Profiling *

Author

Francesco, Laura Di, primary, Girolamo, Francesco Di, additional, Mennini, Maurizio, additional, Masotti, Andrea, additional, Salvatori, Guglielmo, additional, Rigon, Giuliano, additional, Signore, Fabrizio, additional, Pietrantoni, Emanuela, additional, Scapaticci, Margherita, additional, Lante, Isabella, additional, Goffredo, Bianca Maria, additional, Mazzina, Oscar, additional, Elbousify, Ahmed Ibrahim, additional, Roncada, Paola, additional, Dotta, Andrea, additional, Fiocchi, Alessandro, additional, and Putignani, Lorenza, additional

Published
2020
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3. Proceedings of the 2017 WAO Symposium on Hot Topics in Allergy: Pediatric & Regulatory Aspects: Rome, Italy/Vatican City. 27-29 April 2017

Author

Traina, Giovanni, Valluzzi, Rocco Luigi, Fierro, Vincenzo, Riccardi, Carla, Artesani, Maria Cristina, De Vuono, Andrea, Fiocchi, Alessandro, Martelli, Alberto G, Ríos, Luis Alberto, Alcocer, Christian R, Navarrete, Elsy, Del Rio Navarro, Blanca Estela, Gonzalez, Victor, Velasco, Berenice, Perez Aviles, Herberth J, Fernandez, Roberto Jose, Pozo, F Cesar, Farhan, Abdal Jabbar, Arshad, Hasan, Hussain, Ahmed, Sharikadze, Olena, Okhotnikova, Olena, Alcover, Javier, Rodriguez, Diego, Pineda, Fernando, Dalal, Ilan, Weinbrand-Goichberg, Jenny, Benor, Shira, Rottem, Menachem, Kivity, Shmuel, Sato, Sakura, Yanagida, Noriyuki, Ebisawa, Motohiro, Umanets, Tetiana, Antipkin, Youriy, Barzylovich, Vladyslava, Lapshyn, Volodymyr, Umanets, Mykola, Yuriev, Sergey, Bekir, Suzan, Pincock, Tobias, Vieira Hernandez, Alberto, Capriles Hulett, Arnaldo, Sánchez Borges, Mario, Fabiano, Fabiola, Albarran, Carlos, Goyal, Rohit, Gupta, Shilpa, Gaurav, Garg, Luskin, Allan T, Griffin, Noelle M, Wagelie-Steffen, Amy, Trzaskoma, Benjamin L, Limb, Susan L, Busse, William W, Zeiger, Robert S, Gonzalez-Reyes, Erika, Casale, Thomas B, Chipps, Bradley E, Sugizaki, Chizuko, Goto, Fumiko, Yamaide, Akiko, Mitsunaga, Kanako, Tomiita, Minako, Hoshioka, Akira, Shimojo, Naoki, Pop, Liviu L, Ciucǎ, Ioana-Mihaela, Tǎmaş, Liviu, Lazarescu, Marilena, Pienar, Corina, Yamaide, Fumiya, Fikri, Bahrul, Sato, Hironori, Okishima, Naoko, Kobayashi, Miyabi, Takai, Mizuki, Nishigata, Kotarou, Yoda, Ryou, Oana, Yu-Ta, Kajiwara, Chifu, Shimodaira, Moe, Suzuki, Tomoka, Iizawa, Hiromi, Kamijo, Koji, Karmakar, Bijoya, Bhattacharya, Swati Gupta, Blohlávková, Simona, Kopelentová, Eliška, Víšek, Petr, Štádler, Jakub, Šetinová, Ivana, Novobílská, Jana, Lundelin, Krisa, Salminen, Seppo, Isolauri, Erika, Pitt, Tracy, Flanders, Tamar, Peñalver, Marcos, Martínez, Patricia, Lluch, Magdalena, Malet, Alfonso, Nam, Young-Hee, Jin, Hyun Jung, Lee, Soo-Keol, Kulalert, Prapasri, Sritipsukho, Paskorn, Pathumanond, Jayanton, Baynova, Krasimira, Labella, Marina, De Aramburu, Teresa, Prados, Manuel, Haanpää, Leena, Aarnio, Jasmin, Nermes, Merja, Af Ursin, Piia, Kaljonen, Anne, Bala, Nandana, Bhagwat, Ketaki, Hindley, James, Chapman, Martin, Baalasubramanian, Sivasankar, Besednjak-Kocijančič, Lilijana, SenGupta, Koyel, Antonova, Evgeniya, Kong, Amanda M, Iqbal, Ahmar, Teague, W Gerald, Trzaskoma, Benjamin, Ortiz, Benjamin, Paknis, Brandee, Iqbal, Amar, Rosen, Karin, Szefler, Stanley, Alblooshi, Afaf, Al-Hammadi, Suleiman, Vega, Arantza, Gutiérrez-Rivas, Raquel, Alonso, Ana Maria, Beitia, Juan Maria, Belén Mateo, Maria, Cárdenas, Remedios, García-Domínguez, Juan Jesús, Pitchon Dos Reis, Raquel, Gonçalves Alvim, Cristina, Andrade, Claudia, Reis, Adriana, Ribeiro, Henrique, Panaitescu Bunu, Carmen, Marusciac, Laura, Paralescu, Sorin, Tamas, Paul, Panitescu Bunu, Carmen, Martí Guadaño, Enrique, Escobar Bolaños, Carolina, Martí José, Natalia, Pau Casanovas, Pol, Biarnés Rib, Gemma, Castells, Mariana, de Vicente Jiménez, Talía, Mennini, Maurizio, De Angelis, Papola, Rea, Francesca, Malamisura, Monica, Tambucci, Renato, Dall'Oglio, Luigi, Del Chierico, Federica, Napolitano, Tania, Reddel, Silvia, Vernocchi, Pamela, D'Ambrosio, Angelo, Putignani, Lorenza, Dahdah, Lamia, Banzato, Claudia, Echeverría Zudaire, Luís Angel, Plaza, Ana María, Bosque García, Montserrat, Íbero, Marcel, Mazzina, Oscar, Marzano, Valeria, Pecora, Valeria, Koch, Pierluigi, Pecora, Valentina, Valentini, Diletta, Santamaria, Francesca, Valluzzi, Rocco, Mukherjee, Anwesha, Kandhare, Amit, and Bodhankar, Subhash

Published
2017

4. A MALDI-TOF MS Approach for Mammalian, Human, and Formula Milks’ Profiling

Author

Di Francesco, Laura, primary, Di Girolamo, Francesco, additional, Mennini, Maurizio, additional, Masotti, Andrea, additional, Salvatori, Guglielmo, additional, Rigon, Giuliano, additional, Signore, Fabrizio, additional, Pietrantoni, Emanuela, additional, Scapaticci, Margherita, additional, Lante, Isabella, additional, Goffredo, Bianca, additional, Mazzina, Oscar, additional, Elbousify, Ahmed, additional, Roncada, Paola, additional, Dotta, Andrea, additional, Fiocchi, Alessandro, additional, and Putignani, Lorenza, additional

Published
2018
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5. Apheresis in food allergies

Author

Dahdah, Lamia, primary, Leone, Giovanna, additional, Artesani, Mariacristina, additional, Riccardi, Carla, additional, and Mazzina, Oscar, additional

Published
2017
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7. Proceedings of the 2017 WAO Symposium on Hot Topics in Allergy: Pediatric & Regulatory Aspects

Author

Traina, Giovanni, Valluzzi, Rocco Luigi, Fierro, Vincenzo, Riccardi, Carla, Artesani, Maria Cristina, De Vuono, Andrea, Fiocchi, Alessandro, Martelli, Alberto G., Ríos, Luis Alberto, Alcocer, Christian R., Navarrete, Elsy, Del Rio Navarro, Blanca Estela, Gonzalez, Victor, Velasco, Berenice, Perez Aviles, Herberth J., Fernandez, Roberto Jose, Pozo, F. Cesar, Farhan, Abdal Jabbar, Arshad, Hasan, Hussain, Ahmed, Sharikadze, Olena, Okhotnikova, Olena, Alcover, Javier, Rodriguez, Diego, Pineda, Fernando, Dalal, Ilan, Weinbrand-Goichberg, Jenny, Benor, Shira, Rottem, Menachem, Kivity, Shmuel, Sato, Sakura, Yanagida, Noriyuki, Ebisawa, Motohiro, Umanets, Tetiana, Antipkin, Youriy, Barzylovich, Vladyslava, Lapshyn, Volodymyr, Umanets, Mykola, Yuriev, Sergey, Bekir, Suzan, Pincock, Tobias, Vieira Hernandez, Alberto, Capriles Hulett, Arnaldo, Sánchez Borges, Mario, Fabiano, Fabiola, Albarran, Carlos, Goyal, Rohit, Gupta, Shilpa, Gaurav, Garg, Luskin, Allan T., Griffin, Noelle M., Wagelie-Steffen, Amy, Trzaskoma, Benjamin L., Limb, Susan L., Busse, William W., Zeiger, Robert S., Gonzalez-Reyes, Erika, Casale, Thomas, Chipps, Bradley E., Sugizaki, Chizuko, Goto, Fumiko, Yamaide, Akiko, Mitsunaga, Kanako, Tomiita, Minako, Hoshioka, Akira, Shimojo, Naoki, Pop, Liviu L., Ciucǎ, Ioana-Mihaela, Tǎmaş, Liviu, Lazarescu, Marilena, Pienar, Corina, Yamaide, Fumiya, Fikri, Bahrul, Sato, Hironori, Okishima, Naoko, Kobayashi, Miyabi, Takai, Mizuki, Nishigata, Kotarou, Yoda, Ryou, Oana, Yu-ta, Kajiwara, Chifu, Shimodaira, Moe, Suzuki, Tomoka, Iizawa, Hiromi, Kamijo, Koji, Karmakar, Bijoya, Bhattacharya, Swati Gupta, Blohlávková, Simona, Kopelentová, Eliška, Víšek, Petr, Štádler, Jakub, Šetinová, Ivana, Novobílská, Jana, Lundelin, Krisa, Salminen, Seppo, Isolauri, Erika, Pitt, Tracy, Flanders, Tamar, Peñalver, Marcos, Martínez, Patricia, Lluch, Magdalena, Malet, Alfonso, Nam, Young-Hee, Jin, Hyun Jung, Lee, Soo-Keol, Kulalert, Prapasri, Sritipsukho, Paskorn, Pathumanond, Jayanton, Baynova, Krasimira, Labella, Marina, De Aramburu, Teresa, Prados, Manuel, Haanpää, Leena, Aarnio, Jasmin, Nermes, Merja, af Ursin, Piia, Kaljonen, Anne, Bala, Nandana, Bhagwat, Ketaki, Hindley, James, Chapman, Martin, Baalasubramanian, Sivasankar, Besednjak-Kocijančič, Lilijana, SenGupta, Koyel, Antonova, Evgeniya, Kong, Amanda M., Iqbal, Ahmar, Teague, W. Gerald, Trzaskoma, Benjamin, Ortiz, Benjamin, Paknis, Brandee, Iqbal, Amar, Rosen, Karin, Szefler, Stanley, Alblooshi, Afaf, Al-Hammadi, Suleiman, Vega, Arantza, Gutiérrez-Rivas, Raquel, Alonso, Ana Maria, Beitia, Juan Maria, Belén Mateo, Maria, Cárdenas, Remedios, García-Domínguez, Juan Jesús, Pitchon dos Reis, Raquel, Gonçalves Alvim, Cristina, Andrade, Claudia, Reis, Adriana, Ribeiro, Henrique, Panaitescu Bunu, Carmen, Marusciac, Laura, Paralescu, Sorin, Tamas, Paul, Panitescu Bunu, Carmen, Martí Guadaño, Enrique, Escobar Bolaños, Carolina, Martí José, Natalia, Pau Casanovas, Pol, Biarnés Rib, Gemma, Castells, Mariana, de Vicente Jiménez, Talía, Mennini, Maurizio, De Angelis, Papola, Rea, Francesca, Malamisura, Monica, Tambucci, Renato, Dall'Oglio, Luigi, Del Chierico, Federica, Napolitano, Tania, Reddel, Silvia, Vernocchi, Pamela, D'Ambrosio, Angelo, Putignani, Lorenza, Dahdah, Lamia, Banzato, Claudia, Echeverría Zudaire, Luís Angel, Plaza, Ana María, Bosque, Montserrat, Íbero, Marcel, Mazzina, Oscar, Marzano, Valeria, Pecora, Valeria, Koch, Pierluigi, Pecora, Valentina, Valentini, Diletta, Santamaria, Francesca, Mukherjee, Anwesha, Kandhare, Amit, Bodhankar, Subhash, and Universitat Autònoma de Barcelona

Subjects
lcsh:Immunologic diseases. Allergy, Pulmonary and Respiratory Medicine, business.industry, Immunology, MEDLINE, Library science, Meeting Abstracts, Vatican City, Hot topics, Immunology and Allergy, Medicine, lcsh:RC581-607, business
Published
2017

10. Sensitization pattern to inhalant and food allergens in symptomatic children at first evaluation

Author

Fiocchi, Alessandro, Pecora, Valentina, Petersson, Carl Johan, Dahdah, Lamia, Borres, Magnus P., Amengual, Maria J., Huss-Marp, Johannes, Mazzina, Oscar, Di Girolamo, Francesco, Fiocchi, Alessandro, Pecora, Valentina, Petersson, Carl Johan, Dahdah, Lamia, Borres, Magnus P., Amengual, Maria J., Huss-Marp, Johannes, Mazzina, Oscar, and Di Girolamo, Francesco

Abstract

Background: Data on specific IgE sensitization prevalence in children with allergy-like symptoms seen in the primary care setting are rare. Early diagnosis of allergic diseases is important to prevent clinical manifestations, exacerbations or expansion of allergic diseases to other organ systems. The present study aims to assess the usefulness of early serological diagnosis in children with common allergic symptoms. Methods: 532 children (<15 years of age), with at least one of ten allergy-like symptoms, from 21 primary care centers in two geographic areas of Italy and Spain were included in the study. Patients were tested with, either Phadiatop (R) Infant (0-5 years of age) or Phadiatop (R) and food mix (fx5e) (>5 years of age) to discriminate atopic from non-atopic subjects. A blood sample of atopic subjects was taken for additional 6-26 specific IgE antibody determinations from a predefined panel using the ImmunoCAP (R) System. Results: 267 children (50.2 %) were positive in the initial test and were classified as atopic. 14 % were mono-sensitized, 37 % were sensitized to 2-3 allergens and 49 % to more than 3 allergens. The average number of symptoms in the atopic group was 3.3 vs 2.8 in the non-atopic group. The prevalence of sensitization to single allergens was highest for grass and ragweed pollen and house-dust mites (19-28 %). Sensitization to tree allergens was highest for olive tree (16.5 %). Cow's milk and egg white were the most sensitizing foods (similar to 15 %). Food allergen sensitization predominated in younger children (OR = 2.8) whereas the inverse occurred with inhalant allergens (OR = 2.5 to 5.6). A significant positive correlation between patient age and the number of sensitizations was found. Conclusions: Specific IgE sensitization in children with allergy-like symptoms is common. Multiple sensitization is predominating. Number of clinical symptoms was higher in the atopic group compared to the non-atopic without a correlation with the n

Published
2015
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12. Streptococcus pneumoniae colonisation in children and adolescents with asthma: impact of the heptavalent pneumococcal conjugate vaccine and evaluation of potential effect of thirteen-valent pneumococcal conjugate vaccine

Author

Esposito, Susanna, primary, Terranova, Leonardo, additional, Patria, Maria Francesca, additional, Marseglia, Gian Luigi, additional, Miraglia del Giudice, Michele, additional, Bodini, Alessandro, additional, Martelli, Alberto, additional, Baraldi, Eugenio, additional, Mazzina, Oscar, additional, Tagliabue, Claudia, additional, Licari, Amelia, additional, Ierardi, Valentina, additional, Lelii, Mara, additional, and Principi, Nicola, additional

Published
2015
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15. Streptococcus pneumoniae colonisation in children and adolescents with asthma: impact of the heptavalent pneumococcal conjugate vaccine and evaluation of potential effect of thirteen-valent pneumococcal conjugate vaccine.

Author

Esposito, Susanna, Terranova, Leonardo, Patria, Maria Francesca, Marseglia, Gian Luigi, del Giudice, Michele Miraglia, Bodini, Alessandro, Martelli, Alberto, Baraldi, Eugenio, Mazzina, Oscar, Tagliabue, Claudia, Licari, Amelia, Ierardi, Valentina, Lelii, Mara, Principi, Nicola, and Miraglia Del Giudice, Michele

Subjects
STREPTOCOCCUS pneumoniae, ASTHMA in children, PNEUMOCOCCAL vaccines, RESPIRATORY diseases, CHRONIC diseases, LUNG diseases, BACTERIAL colonies, ASTHMA prevention, NASOPHARYNX microbiology, STREPTOCOCCAL disease prevention, ASTHMA, CLINICAL trials, COMPARATIVE studies, CLINICAL drug trials, RESEARCH methodology, MEDICAL cooperation, RESEARCH, STREPTOCOCCAL diseases, STREPTOCOCCUS, VACCINES, EVALUATION research, PHYSIOLOGY
Abstract

Background: The main aim of this study was to evaluate Streptococcus pneumoniae carriage in a group of school-aged children and adolescents with asthma because these results might indicate the theoretical risk of invasive pneumococcal disease (IPD) of such patients and the potential protective efficacy of the 13-valent pneumococcal conjugate vaccine (PCV13).Methods: Oropharyngeal samples were obtained from 423 children with documented asthma (300 males, 70.9%), and tested for the autolysin-A-encoding (lytA) and the wzg (cpsA) gene of S. pneumoniae by means of real-time polymerase chain reaction.Results: S. pneumoniae was identified in the swabs of 192 subjects (45.4%): 48.4% of whom were aged <10 years, 46.9% aged 10-14 years, and 4.7% aged ≥15 years (p < 0.001). Carriage was significantly less frequent among the children who had received recent antibiotic therapy (odds ratio [OR 0.41]; 95% confidence interval [95% CI] 0.22-0.76). Multivariate analyses showed no association between carriage and vaccination status, with ORs of 1.05 (95% CI 0.70-1.58) for carriers of any pneumococcal serotype, 1.08 (95% CI 0.72-1.62) for carriers of any of the serotypes included in 7-valent pneumococcal conjugate vaccine (PCV7), and 0.76 (95% CI 0.45-1.28) for carriers of any of the six additional serotypes of PCV13. Serotypes 19 F, 4 and 9 V were the most frequently identified serotypes in vaccinated subjects.Conclusions: These results showed that carriage of S. pneumoniae is relatively common in all school-aged children and adolescents with asthma, regardless of the severity of disease and the administration of PCV7 in the first years of life. This highlights the problem of the duration of the protection against colonisation provided by pneumococcal conjugate vaccine, and the importance of re-colonization by the same pneumococcal serotypes included in the previously used vaccine. [ABSTRACT FROM AUTHOR]

Published
2016
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16. Streptococcus pneumoniae colonisation in children and adolescents with asthma: Impact of the heptavalent pneumococcal conjugate vaccine and evaluation of potential effect of thirteen-valent pneumococcal conjugate vaccine

Author

Mara Lelii, Oscar Mazzina, Eugenio Baraldi, Gian Luigi Marseglia, Susanna Esposito, Arabella Martelli, Alessandro Bodini, Maria Francesca Patria, Valentina Ierardi, Michele Miraglia Del Giudice, Leonardo Terranova, Amelia Licari, Nicola Principi, Claudia Tagliabue, Esposito, Susanna, Terranova, Leonardo, Patria, Maria Francesca, Marseglia, Gian Luigi, MIRAGLIA DEL GIUDICE, Michele, Bodini, Alessandro, Martelli, Alberto, Baraldi, Eugenio, Mazzina, Oscar, Tagliabue, Claudia, Licari, Amelia, Ierardi, Valentina, Lelii, Mara, and Principi, Nicola

Subjects
0301 basic medicine, Male, Heptavalent Pneumococcal Conjugate Vaccine, PCV13, medicine.disease_cause, Pneumococcal conjugate vaccine, Asthma, Asthmatic children, Chronic respiratory disease, PCV7, Pneumococcal colonisation, Pulmonary disease, Streptococcus pneumoniae, Infectious Diseases, 0302 clinical medicine, Medical microbiology, vaccine, Nasopharynx, 030212 general & internal medicine, Child, Streptococcus, Pneumococcal infections, Child, Preschool, Female, Research Article, medicine.drug, Human, medicine.medical_specialty, Adolescent, Pneumococcal Infection, Pneumococcal Infections, 03 medical and health sciences, medicine, Humans, Vaccines, Conjugate, business.industry, medicine.disease, Streptococcus, asthma, vaccine, 030104 developmental biology, Carriage, Immunology, Drug Evaluation, business
Abstract

Background The main aim of this study was to evaluate Streptococcus pneumoniae carriage in a group of school-aged children and adolescents with asthma because these results might indicate the theoretical risk of invasive pneumococcal disease (IPD) of such patients and the potential protective efficacy of the 13-valent pneumococcal conjugate vaccine (PCV13). Methods Oropharyngeal samples were obtained from 423 children with documented asthma (300 males, 70.9 %), and tested for the autolysin-A-encoding (lytA) and the wzg (cpsA) gene of S. pneumoniae by means of real-time polymerase chain reaction. Results S. pneumoniae was identified in the swabs of 192 subjects (45.4 %): 48.4 % of whom were aged

Published
2016

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