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397 results on '"Maurillo, Luca"'

1. Evolution of transcriptomic profiles in relapsed inv(16) acute myeloid leukemia

Author

Travaglini, Serena, Silvestrini, Giorgia, Attardi, Enrico, Fanciulli, Maurizio, Scalera, Stefano, Antonelli, Silvia, Maurillo, Luca, Palmieri, Raffaele, Divona, Mariadomenica, Ciuffreda, Ludovica, Savi, Arianna, Paterno, Giovangiacinto, Ottone, Tiziana, Barbieri, Caterina, Maciejewski, Jaroslaw P., Gurnari, Carmelo, Ciliberto, Gennaro, and Voso, Maria Teresa

Published
2024
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3. MCL1 regulates AML cells metabolism via direct interaction with HK2. Metabolic signature at onset predicts overall survival in AMLs’ patients

Author

Catalano, Gianfranco, Zaza, Alessandra, Banella, Cristina, Pelosi, Elvira, Castelli, Germana, de Marinis, Elisabetta, Smigliani, Ariela, Travaglini, Serena, Ottone, Tiziana, Divona, Mariadomenica, Del Principe, Maria Ilaria, Buccisano, Francesco, Maurillo, Luca, Ammatuna, Emanuele, Testa, Ugo, Nervi, Clara, Venditti, Adriano, Voso, Maria Teresa, and Noguera, Nelida Ines

Published
2023
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4. The ISTH DIC-score predicts early mortality in patients with non-promyelocitic acute myeloid leukemia

Author

Paterno, Giovangiacinto, Palmieri, Raffaele, Tesei, Cristiano, Nunzi, Andrea, Ranucci, Giorgia, Mallegni, Flavia, Moretti, Federico, Meddi, Elisa, Tiravanti, Ilaria, Marinoni, Massimiliano, Page, Camilla, Fagiolo, Solaria, Buzzatti, Elisa, Secchi, Roberto, Gurnari, Carmelo, Maurillo, Luca, Buccisano, Francesco, Venditti, Adriano, and Del Principe, Maria Ilaria

Published
2024
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5. Safety and effectiveness of ruxolitinib in the real-world management of polycythemia vera patients: a collaborative retrospective study by pH-negative MPN latial group

Author

Pepe, Sara, Rossi, Elena, Trawinska, Malgorzata, Tatarelli, Caterina, Di Veroli, Ambra, Maurillo, Luca, Romano, Atelda, Crescenzi, Sabrina Leonetti, di Toritto, Tommaso Caravita, Tafuri, Agostino, Latagliata, Roberto, Scalzulli, Emilia, Andriani, Alessandro, De Stefano, Valerio, and Breccia, Massimo

Published
2022
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7. ELN2017 risk stratification improves outcome prediction when applied to the prospective GIMEMA AML1310 protocol

Author

Buccisano, Francesco, Palmieri, Raffaele, Piciocchi, Alfonso, Arena, Valentina, Candoni, Anna, Melillo, Lorella, Calafiore, Valeria, Cairoli, Roberto, de Fabritiis, Paolo, Storti, Gabriella, Salutari, Prassede, Lanza, Francesco, Martinelli, Giovanni, Luppi, Mario, Capria, Saveria, Maurillo, Luca, Del Principe, Maria Ilaria, Paterno, Giovangiacinto, Irno Consalvo, Maria Antonietta, Ottone, Tiziana, Lavorgna, Serena, Voso, Maria Teresa, Fazi, Paola, Vignetti, Marco, Arcese, William, and Venditti, Adriano

Published
2022
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8. Myelodysplastic syndromes with del(5q): A real-life study of determinants of long-term outcomes and response to lenalidomide

Author

Gurnari, Carmelo, Piciocchi, Alfonso, Soddu, Stefano, Bonanni, Fabrizio, Scalzulli, Emilia, Niscola, Pasquale, Di Veroli, Ambra, Piccioni, Anna Lina, Piedimonte, Monica, Maiorana, Gianluca, Salutari, Prassede, Cicconi, Laura, Santopietro, Michelina, Gumenyuk, Svitlana, Sarlo, Chiara, Fenu, Susanna, Tafuri, Agostino, Latagliata, Roberto, Fianchi, Luana, Criscuolo, Marianna, Maciejewski, Jaroslaw P., Maurillo, Luca, Buccisano, Francesco, Breccia, Massimo, and Voso, Maria Teresa

Published
2022
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10. GIMEMA AML1310 trial of risk-adapted, MRD-directed therapy for young adults with newly diagnosed acute myeloid leukemia

Author

Venditti, Adriano, Piciocchi, Alfonso, Candoni, Anna, Melillo, Lorella, Calafiore, Valeria, Cairoli, Roberto, de Fabritiis, Paolo, Storti, Gabriella, Salutari, Prassede, Lanza, Francesco, Martinelli, Giovanni, Luppi, Mario, Mazza, Patrizio, Martelli, Maria Paola, Cuneo, Antonio, Albano, Francesco, Fabbiano, Francesco, Tafuri, Agostino, Chierichini, Anna, Tieghi, Alessia, Fracchiolla, Nicola Stefano, Capelli, Debora, Foà, Robin, Alati, Caterina, La Sala, Edoardo, Fazi, Paola, Vignetti, Marco, Maurillo, Luca, Buccisano, Francesco, Del Principe, Maria Ilaria, Irno-Consalvo, Maria, Ottone, Tiziana, Lavorgna, Serena, Voso, Maria Teresa, Lo-Coco, Francesco, Arcese, William, and Amadori, Sergio

Published
2019
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11. Deferasirox in the treatment of iron overload during myeloproliferative neoplasms in fibrotic phase: does ferritin decrement matter?

Author

Di Veroli, Ambra, Campagna, Alessia, De Muro, Marianna, Maurillo, Luca, Trawinska, Malgorzata Monika, LeonettiCrescenzi, Sabrina, Petriccione, Luca, Romano, Atelda, D’Addosio, Ada, Cenfra, Antonia, Montanaro, Marco, Felici, Stefano, Andriani, Alessandro, Carmosino, Ida, Niscola, Pasquale, Montefusco, Enrico, Breccia, Massimo, and Latagliata, Roberto

Published
2019
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12. Risk-adapted MRD-directed therapy for young adults with acute myeloid leukemia: 6-year update of the GIMEMA AML1310 trial

Author

Venditti, Adriano, Piciocchi, Alfonso, Candoni, Anna, Arena, Valentina, Palmieri, Raffaele, Filì, Carla, Carella, Angelo Michele, Calafiore, Valeria, Cairoli, Roberto, de Fabritiis, Paolo, Storti, Gabriella, Salutari, Prassede, Lanza, Francesco, Martinelli, Giovanni, Curti, Antonio, Luppi, Mario, Ingrosso, Claudia, Martelli, Maria Paola, Cuneo, Antonio, Albano, Francesco, Mulè, Antonino, Tafuri, Agostino, Cudillo, Laura, Tieghi, Alessia, Fracchiolla, Nicola Stefano, Capelli, Debora, Trisolini, Silvia Maria, Alati, Caterina, La Sala, Edoardo, Maurillo, Luca, Del Principe, Maria Ilaria, Irno Consalvo, Maria Antonietta, Divona, Maria Domenica, Ottone, Tiziana, Cerretti, Raffaella, Sconocchia, Giuseppe, Voso, Maria Teresa, Fazi, Paola, Vignetti, Marco, and Buccisano, Francesco

Published
2024
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13. Minimal/measurable residual disease in AML: a consensus document from the European LeukemiaNet MRD Working Party

Author

Schuurhuis, Gerrit J., Heuser, Michael, Freeman, Sylvie, Béné, Marie-Christine, Buccisano, Francesco, Cloos, Jacqueline, Grimwade, David, Haferlach, Torsten, Hills, Robert K., Hourigan, Christopher S., Jorgensen, Jeffrey L., Kern, Wolfgang, Lacombe, Francis, Maurillo, Luca, Preudhomme, Claude, van der Reijden, Bert A., Thiede, Christian, Venditti, Adriano, Vyas, Paresh, Wood, Brent L., Walter, Roland B., Döhner, Konstanze, Roboz, Gail J., and Ossenkoppele, Gert J.

Published
2018
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15. P505: GIMEMA AML1819 TRIAL: GEMTUZUMAB OZOGAMICIN PLUS INTENSIVE CHEMOTHERAPY IMPACTS ON THE LEVEL OF POST-CONSOLIDATION MEASURABLE RESIDUAL DISEASE (MRD) IN ACUTE MYELOID LEUKEMIA

Author

Venditti, Adriano, primary, Piciocchi, Alfonso, additional, Maurillo, Luca, additional, Ilaria Del Principe, Maria, additional, Palmieri, Raffaele, additional, Soddu, Stefano, additional, Moretti, Federico, additional, Salutari, Prassede, additional, Martelli, Maurizio, additional, Paola Martelli, Maria, additional, Luppi, Mario, additional, Pulsoni, Alessandro, additional, Zaja, Francesco, additional, Cairoli, Roberto, additional, Pane, Fabrizio, additional, Siragusa, Sergio, additional, Bassan, Renato, additional, Rondoni, Michela, additional, Mirabile, Milena, additional, Mulè, Antonino, additional, Beltrami, Germana, additional, Zappasodi, Patrizia, additional, Cudillo, Laura, additional, Mengarelli, Andrea, additional, Curti, Antonio, additional, Ferrara, Felicetto, additional, Rossi, Giovanni, additional, Audisio, Ernesta, additional, Spinosa, Giuseppina, additional, Tieghi, Alessia, additional, Bocchia, Monica, additional, Martini, Vincenza, additional, Califano, Catello, additional, Rigacci, Luigi, additional, Tafuri, Agostino, additional, Gottardi, Michele, additional, Fazi, Paola, additional, Vignetti, Marco, additional, and Buccisano, Francesco, additional

Published
2023
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16. P432: VALIDATION OF LIMIT OF QUANTIFICATION APPROACH BASED FLOW CYTOMETRY FOR MEASURABLE RESIDUAL DISEASE ASSESSMENT IN ACUTE MYELOID LEUKEMIA IN THE HOVON-SAKK-132 TRIAL

Author

Tettero, Jesse, primary, Palmieri, Raffaele, additional, Lam Ngai, Lok, additional, Bachas, Costa, additional, Arena, Valentina, additional, Breems, Dimitri, additional, Fischer, Thomas, additional, Tore Gjertsen, Bjorn, additional, Griškevičius, Laimonas, additional, Juliusson, Gunnar, additional, Maertens, Johan, additional, Manz, Markus, additional, Maurillo, Luca, additional, Pabst, Thomas, additional, Passweg, Jakob, additional, Piciocchi, Alfonso, additional, Porkka, Kimmo, additional, Löwenberg, Bob, additional, Venditti, Adriano, additional, Ossenkoppele, Gert, additional, Buccisano, Francesco, additional, and Cloos, Jacqueline, additional

Published
2023
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18. AVALON: The Italian cohort study on real-life efficacy of hypomethylating agents plus venetoclax in newly diagnosed or relapsed/refractory patients with acute myeloid leukemia

Author

Todisco, Elisabetta, Papayannidis, Cristina, Fracchiolla, Nicola, Petracci, Elisabetta, Zingaretti, Chiara, Vetro, Calogero, Martelli, Maria Paola, Zappasodi, Patrizia, Di Renzo, Nicola, Gallo, Susanna, Audisio, Ernesta, Griguolo, Davide, Cerchione, Claudio, Selleri, Carmine, Mattei, Daniele, Bernardi, Massimo, Fumagalli, Monica, Rizzuto, Giuliana, Facchini, Luca, Basilico, Claudia Maria, Manfra, Ilenia, Borlenghi, Erika, Cairoli, Roberto, Salutari, Prassede, Gottardi, Michele, Molteni, Alfredo, Martini, Vincenza, Lunghi, Monia, Fianchi, Luana, Cilloni, Daniela, Lanza, Francesco, Abruzzese, Elisabetta, Cascavilla, Nicola, Rivellini, Flavia, Ferrara, Felicetto, Maurillo, Luca, Nanni, Jacopo, Romano, Alessandra, Cardinali, Valeria, Gigli, Federica, Roncoroni, Elisa, Federico, Vincenzo, Marconi, Giovanni, Volpi, Roberta, Sciumè, Mariarita, Tarella, Corrado, Rossi, Giuseppe, Martinelli, Giovanni, Todisco, Elisabetta, Papayannidis, Cristina, Fracchiolla, Nicola, Petracci, Elisabetta, Zingaretti, Chiara, Vetro, Calogero, Martelli, Maria Paola, Zappasodi, Patrizia, Di Renzo, Nicola, Gallo, Susanna, Audisio, Ernesta, Griguolo, Davide, Cerchione, Claudio, Selleri, Carmine, Mattei, Daniele, Bernardi, Massimo, Fumagalli, Monica, Rizzuto, Giuliana, Facchini, Luca, Basilico, Claudia Maria, Manfra, Ilenia, Borlenghi, Erika, Cairoli, Roberto, Salutari, Prassede, Gottardi, Michele, Molteni, Alfredo, Martini, Vincenza, Lunghi, Monia, Fianchi, Luana, Cilloni, Daniela, Lanza, Francesco, Abruzzese, Elisabetta, Cascavilla, Nicola, Rivellini, Flavia, Ferrara, Felicetto, Maurillo, Luca, Nanni, Jacopo, Romano, Alessandra, Cardinali, Valeria, Gigli, Federica, Roncoroni, Elisa, Federico, Vincenzo, Marconi, Giovanni, Volpi, Roberta, Sciumè, Mariarita, Tarella, Corrado, Rossi, Giuseppe, Martinelli, Giovanni, Todisco, E, Papayannidis, C, Fracchiolla, N, Petracci, E, Zingaretti, C, Vetro, C, Martelli, M, Zappasodi, P, Di Renzo, N, Gallo, S, Audisio, E, Griguolo, D, Cerchione, C, Selleri, C, Mattei, D, Bernardi, M, Fumagalli, M, Rizzuto, G, Facchini, L, Basilico, C, Manfra, I, Borlenghi, E, Cairoli, R, Salutari, P, Gottardi, M, Molteni, A, Martini, V, Lunghi, M, Fianchi, L, Cilloni, D, Lanza, F, Abruzzese, E, Cascavilla, N, Rivellini, F, Ferrara, F, Maurillo, L, Nanni, J, Romano, A, Cardinali, V, Gigli, F, Roncoroni, E, Federico, V, Marconi, G, Volpi, R, Sciumè, M, Tarella, C, Rossi, G, and Martinelli, G

Subjects
Cancer Research, hypomethylating agents, Oncology, hypomethylating agent, relapsed and refractory AML, venetoclax, real-life data, acute myeloid leukemia
Abstract

Background: Venetoclax in combination with hypomethylating agents (HMA) is revolutionizing the therapy of acute myeloid leukemia (AML). However, evidence on large sets of patients is lacking, especially in relapsed or refractory leukemia. Methods: AVALON is a multicentric cohort study that was conducted in Italy on patients with AML who received venetoclax-based therapies from 2015 to 2020. The study was approved by the ethics committee of the participating institution and was conducted in accordance with the Declaration of Helsinki. The effectiveness and toxicity of venetoclax+HMA in 190 (43 newly diagnosed, 68 refractory, and 79 relapsed) patients with AML are reported here. Results: In the newly diagnosed AML, the overall response rate and survival confirmed the brilliant results demonstrated in VIALE-A. In the relapsed or refractory AML, the combination demonstrated a surprisingly complete remission rate (44.1% in refractory and 39.7% in relapsed evaluable patients) and conferred to treated patients a good expectation of survival. Toxicities were overall manageable, and most incidents occurred in the first 60days of therapy. Infections were confirmed as the most common nonhematologic adverse event. Conclusions: Real-life data show that the combination of venetoclax and HMA offers an expectation of remission and long-term survival to elderly, newly diagnosed patients, and to relapsed or chemoresistant AML, increasing the chance of cure through a different mechanism of action. The venetoclax+HMA combination is expected to constitute the base for triplet combinations and integration of target therapies. Our data contribute to ameliorate the understanding of venetoclax+HMA effectiveness and toxicities in real life.

Published
2023

20. Supplementary Figure 3 from A Leukemia-Associated CD34/CD123/CD25/CD99+ Immunophenotype Identifies FLT3-Mutated Clones in Acute Myeloid Leukemia

Author

Angelini, Daniela F., primary, Ottone, Tiziana, primary, Guerrera, Gisella, primary, Lavorgna, Serena, primary, Cittadini, Michela, primary, Buccisano, Francesco, primary, De Bardi, Marco, primary, Gargano, Francesca, primary, Maurillo, Luca, primary, Divona, Mariadomenica, primary, Noguera, Nélida I., primary, Consalvo, Maria Irno, primary, Borsellino, Giovanna, primary, Bernardi, Giorgio, primary, Amadori, Sergio, primary, Venditti, Adriano, primary, Battistini, Luca, primary, and Lo-Coco, Francesco, primary

Published
2023
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21. Supplementary Table 4 from A Leukemia-Associated CD34/CD123/CD25/CD99+ Immunophenotype Identifies FLT3-Mutated Clones in Acute Myeloid Leukemia

Author

Angelini, Daniela F., primary, Ottone, Tiziana, primary, Guerrera, Gisella, primary, Lavorgna, Serena, primary, Cittadini, Michela, primary, Buccisano, Francesco, primary, De Bardi, Marco, primary, Gargano, Francesca, primary, Maurillo, Luca, primary, Divona, Mariadomenica, primary, Noguera, Nélida I., primary, Consalvo, Maria Irno, primary, Borsellino, Giovanna, primary, Bernardi, Giorgio, primary, Amadori, Sergio, primary, Venditti, Adriano, primary, Battistini, Luca, primary, and Lo-Coco, Francesco, primary

Published
2023
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22. Supplementary Table 2 from A Leukemia-Associated CD34/CD123/CD25/CD99+ Immunophenotype Identifies FLT3-Mutated Clones in Acute Myeloid Leukemia

Author

Angelini, Daniela F., primary, Ottone, Tiziana, primary, Guerrera, Gisella, primary, Lavorgna, Serena, primary, Cittadini, Michela, primary, Buccisano, Francesco, primary, De Bardi, Marco, primary, Gargano, Francesca, primary, Maurillo, Luca, primary, Divona, Mariadomenica, primary, Noguera, Nélida I., primary, Consalvo, Maria Irno, primary, Borsellino, Giovanna, primary, Bernardi, Giorgio, primary, Amadori, Sergio, primary, Venditti, Adriano, primary, Battistini, Luca, primary, and Lo-Coco, Francesco, primary

Published
2023
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23. Supplementary Figure 2 from A Leukemia-Associated CD34/CD123/CD25/CD99+ Immunophenotype Identifies FLT3-Mutated Clones in Acute Myeloid Leukemia

Author

Angelini, Daniela F., primary, Ottone, Tiziana, primary, Guerrera, Gisella, primary, Lavorgna, Serena, primary, Cittadini, Michela, primary, Buccisano, Francesco, primary, De Bardi, Marco, primary, Gargano, Francesca, primary, Maurillo, Luca, primary, Divona, Mariadomenica, primary, Noguera, Nélida I., primary, Consalvo, Maria Irno, primary, Borsellino, Giovanna, primary, Bernardi, Giorgio, primary, Amadori, Sergio, primary, Venditti, Adriano, primary, Battistini, Luca, primary, and Lo-Coco, Francesco, primary

Published
2023
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24. Supplementary Figure 1 from A Leukemia-Associated CD34/CD123/CD25/CD99+ Immunophenotype Identifies FLT3-Mutated Clones in Acute Myeloid Leukemia

Author

Angelini, Daniela F., primary, Ottone, Tiziana, primary, Guerrera, Gisella, primary, Lavorgna, Serena, primary, Cittadini, Michela, primary, Buccisano, Francesco, primary, De Bardi, Marco, primary, Gargano, Francesca, primary, Maurillo, Luca, primary, Divona, Mariadomenica, primary, Noguera, Nélida I., primary, Consalvo, Maria Irno, primary, Borsellino, Giovanna, primary, Bernardi, Giorgio, primary, Amadori, Sergio, primary, Venditti, Adriano, primary, Battistini, Luca, primary, and Lo-Coco, Francesco, primary

Published
2023
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25. Supplementary Data from Valproic Acid at Therapeutic Plasma Levels May Increase 5-Azacytidine Efficacy in Higher Risk Myelodysplastic Syndromes

Author

Voso, Maria Teresa, primary, Santini, Valeria, primary, Finelli, Carlo, primary, Musto, Pellegrino, primary, Pogliani, Enrico, primary, Angelucci, Emanuele, primary, Fioritoni, Giuseppe, primary, Alimena, Giuliana, primary, Maurillo, Luca, primary, Cortelezzi, Agostino, primary, Buccisano, Francesco, primary, Gobbi, Marco, primary, Borin, Lorenza, primary, Di Tucci, Anna, primary, Zini, Gina, primary, Petti, Maria Concetta, primary, Martinelli, Giovanni, primary, Fabiani, Emiliano, primary, Fazi, Paola, primary, Vignetti, Marco, primary, Piciocchi, Alfonso, primary, Liso, Vincenzo, primary, Amadori, Sergio, primary, and Leone, Giuseppe, primary

Published
2023
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26. Supplementary Table 3 from A Leukemia-Associated CD34/CD123/CD25/CD99+ Immunophenotype Identifies FLT3-Mutated Clones in Acute Myeloid Leukemia

Author

Angelini, Daniela F., primary, Ottone, Tiziana, primary, Guerrera, Gisella, primary, Lavorgna, Serena, primary, Cittadini, Michela, primary, Buccisano, Francesco, primary, De Bardi, Marco, primary, Gargano, Francesca, primary, Maurillo, Luca, primary, Divona, Mariadomenica, primary, Noguera, Nélida I., primary, Consalvo, Maria Irno, primary, Borsellino, Giovanna, primary, Bernardi, Giorgio, primary, Amadori, Sergio, primary, Venditti, Adriano, primary, Battistini, Luca, primary, and Lo-Coco, Francesco, primary

Published
2023
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27. Supplementary Table 1 from A Leukemia-Associated CD34/CD123/CD25/CD99+ Immunophenotype Identifies FLT3-Mutated Clones in Acute Myeloid Leukemia

Author

Angelini, Daniela F., primary, Ottone, Tiziana, primary, Guerrera, Gisella, primary, Lavorgna, Serena, primary, Cittadini, Michela, primary, Buccisano, Francesco, primary, De Bardi, Marco, primary, Gargano, Francesca, primary, Maurillo, Luca, primary, Divona, Mariadomenica, primary, Noguera, Nélida I., primary, Consalvo, Maria Irno, primary, Borsellino, Giovanna, primary, Bernardi, Giorgio, primary, Amadori, Sergio, primary, Venditti, Adriano, primary, Battistini, Luca, primary, and Lo-Coco, Francesco, primary

Published
2023
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28. Supplementary Table 5 from A Leukemia-Associated CD34/CD123/CD25/CD99+ Immunophenotype Identifies FLT3-Mutated Clones in Acute Myeloid Leukemia

Author

Angelini, Daniela F., primary, Ottone, Tiziana, primary, Guerrera, Gisella, primary, Lavorgna, Serena, primary, Cittadini, Michela, primary, Buccisano, Francesco, primary, De Bardi, Marco, primary, Gargano, Francesca, primary, Maurillo, Luca, primary, Divona, Mariadomenica, primary, Noguera, Nélida I., primary, Consalvo, Maria Irno, primary, Borsellino, Giovanna, primary, Bernardi, Giorgio, primary, Amadori, Sergio, primary, Venditti, Adriano, primary, Battistini, Luca, primary, and Lo-Coco, Francesco, primary

Published
2023
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29. Acute leukemia diagnosis during the COVID-19 pandemic

Author

GUARNERA, Luca, primary, BUZZATTI, Elisa, additional, MARCHESI, Francesco, additional, ARMIENTO, Daniele, additional, MAZZONE, Carla, additional, CAPRIA, Saveria, additional, SCALZULLI, Emilia, additional, MALFONA, Francesco, additional, CHIARETTI, Sabina, additional, PALMIERI, Raffaele, additional, PATERNO, Giovangiacinto, additional, FRANZESE, Chiara, additional, BONANNI, Fabrizio, additional, SAVI, Arianna, additional, PASQUALONE, Gianmario, additional, MORETTI, Federico, additional, MAURILLO, Luca, additional, BUCCISANO, Francesco, additional, VENDITTI, Adriano, additional, and DEL PRINCIPE, Maria Ilaria, additional

Published
2023
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30. Real World Outcome of Unfit Patients with Acute Myeloid Leukemia Treated with the Combination Venetoclax Plus Hypomethylating Agents in the Gimema AML2320 Observational Trial

Author

Venditti, A, Piciocchi, A, Soddu, S, Frigeni, M, Palmieri, R, Borlenghi, E, Fracchiolla, N, Martelli, M, Audisio, E, Gianfaldoni, G, Vetro, C, di Rienzo, N, Esposito, D, Di Veroli, A, Selleri, C, Gigli, F, Curti, A, Mulè, A, Califano, C, Bigliardi, S, Breccia, M, Fozza, C, Bocchia, M, Lico, A, Simonetti, F, Pierdomenico, E, Buccisano, F, Del Principe, M, Maurillo, L, Fazi, P, Vignetti, M, Ferrara, F, Cairoli, R, Rossi, G, Rambaldi, A, Venditti, Adriano, Piciocchi, Alfonso, Soddu, Stefano, Frigeni, Marco, Palmieri, Raffaele, Borlenghi, Erika, Fracchiolla, Nicola, Martelli, Maria Paola, Audisio, Ernesta, Gianfaldoni, Giacomo, Vetro, Calogero, di Rienzo, Nicola, Esposito, Daniela, Di Veroli, Ambra, Selleri, Carmine, Gigli, Federica, Curti, Antonio, Mulè, Antonino, Califano, Catello, Bigliardi, Sara, Breccia, Massimo, Fozza, Claudio, Bocchia, Monica, Lico, Albana, Simonetti, Federico, Pierdomenico, Elisabetta, Buccisano, Francesco, Del Principe, Maria Ilaria, Maurillo, Luca, Fazi, Paola, Vignetti, Marco, Ferrara, Felicetto, Cairoli, Roberto, Rossi, Giuseppe, Rambaldi, Alessandro, Venditti, A, Piciocchi, A, Soddu, S, Frigeni, M, Palmieri, R, Borlenghi, E, Fracchiolla, N, Martelli, M, Audisio, E, Gianfaldoni, G, Vetro, C, di Rienzo, N, Esposito, D, Di Veroli, A, Selleri, C, Gigli, F, Curti, A, Mulè, A, Califano, C, Bigliardi, S, Breccia, M, Fozza, C, Bocchia, M, Lico, A, Simonetti, F, Pierdomenico, E, Buccisano, F, Del Principe, M, Maurillo, L, Fazi, P, Vignetti, M, Ferrara, F, Cairoli, R, Rossi, G, Rambaldi, A, Venditti, Adriano, Piciocchi, Alfonso, Soddu, Stefano, Frigeni, Marco, Palmieri, Raffaele, Borlenghi, Erika, Fracchiolla, Nicola, Martelli, Maria Paola, Audisio, Ernesta, Gianfaldoni, Giacomo, Vetro, Calogero, di Rienzo, Nicola, Esposito, Daniela, Di Veroli, Ambra, Selleri, Carmine, Gigli, Federica, Curti, Antonio, Mulè, Antonino, Califano, Catello, Bigliardi, Sara, Breccia, Massimo, Fozza, Claudio, Bocchia, Monica, Lico, Albana, Simonetti, Federico, Pierdomenico, Elisabetta, Buccisano, Francesco, Del Principe, Maria Ilaria, Maurillo, Luca, Fazi, Paola, Vignetti, Marco, Ferrara, Felicetto, Cairoli, Roberto, Rossi, Giuseppe, and Rambaldi, Alessandro

Published
2023

31. Optimal Duration of CPX-351 Treatment and Best Timing for Consolidation with Allogeneic Stem Cell Transplantation: Evidence from a Large Real-World Italian Study

Author

Guolo, F, Fianchi, L, Martelli, M, Chiusolo, P, Lussana, F, Grimaldi, F, Pilo, F, Rondoni, M, Fili, C, Capelli, D, Breccia, M, Mastaglio, S, Bocchia, M, Fumagalli, M, Galimberti, S, Mancini, V, Piccioni, A, Maurillo, L, Palmieri, R, Corbingi, A, Vetro, C, Sperotto, A, Gigli, F, Zappasodi, P, Mulé, A, Borlenghi, E, Dargenio, M, Lessi, F, Cerrano, M, Isidori, A, Brunetti, L, Papayannidis, C, Lunghi, M, Alati, C, Gatani, S, Mannelli, F, Fracchiolla, N, Gottardi, M, Cairoli, R, Ferrara, F, Lemoli, R, Venditti, A, Pagano, L, Todisco, E, Guolo, Fabio, Fianchi, Luana, Martelli, Maria Paola, Chiusolo, Patrizia, Lussana, Federico, Grimaldi, Francesco, Pilo, Federica, Rondoni, Michela, Fili, Carla, Capelli, Debora, Breccia, Massimo, Mastaglio, Sara, Bocchia, Monica, Fumagalli, Monica, Galimberti, Sara, Mancini, Valentina, Piccioni, Anna Lina, Maurillo, Luca, Palmieri, Raffaele, Corbingi, Andrea, Vetro, Calogero, Sperotto, Alessandra, Gigli, Federica, Zappasodi, Patrizia, Mulé, Antonio, Borlenghi, Erika, Dargenio, Michelina, Lessi, Federica, Cerrano, Marco, Isidori, Alessandro, Brunetti, Lorenzo, Papayannidis, Cristina, Lunghi, Monia, Alati, Caterina, Gatani, Samuele, Mannelli, Francesco, Fracchiolla, Nicola, Gottardi, Michele, Cairoli, Roberto, Ferrara, Felicetto, Lemoli, Roberto Massimo, Venditti, Adriano, Pagano, Livio, Todisco, Elisabetta, Guolo, F, Fianchi, L, Martelli, M, Chiusolo, P, Lussana, F, Grimaldi, F, Pilo, F, Rondoni, M, Fili, C, Capelli, D, Breccia, M, Mastaglio, S, Bocchia, M, Fumagalli, M, Galimberti, S, Mancini, V, Piccioni, A, Maurillo, L, Palmieri, R, Corbingi, A, Vetro, C, Sperotto, A, Gigli, F, Zappasodi, P, Mulé, A, Borlenghi, E, Dargenio, M, Lessi, F, Cerrano, M, Isidori, A, Brunetti, L, Papayannidis, C, Lunghi, M, Alati, C, Gatani, S, Mannelli, F, Fracchiolla, N, Gottardi, M, Cairoli, R, Ferrara, F, Lemoli, R, Venditti, A, Pagano, L, Todisco, E, Guolo, Fabio, Fianchi, Luana, Martelli, Maria Paola, Chiusolo, Patrizia, Lussana, Federico, Grimaldi, Francesco, Pilo, Federica, Rondoni, Michela, Fili, Carla, Capelli, Debora, Breccia, Massimo, Mastaglio, Sara, Bocchia, Monica, Fumagalli, Monica, Galimberti, Sara, Mancini, Valentina, Piccioni, Anna Lina, Maurillo, Luca, Palmieri, Raffaele, Corbingi, Andrea, Vetro, Calogero, Sperotto, Alessandra, Gigli, Federica, Zappasodi, Patrizia, Mulé, Antonio, Borlenghi, Erika, Dargenio, Michelina, Lessi, Federica, Cerrano, Marco, Isidori, Alessandro, Brunetti, Lorenzo, Papayannidis, Cristina, Lunghi, Monia, Alati, Caterina, Gatani, Samuele, Mannelli, Francesco, Fracchiolla, Nicola, Gottardi, Michele, Cairoli, Roberto, Ferrara, Felicetto, Lemoli, Roberto Massimo, Venditti, Adriano, Pagano, Livio, and Todisco, Elisabetta

Published
2023

33. FEVER OF UNKNOWN ORIGIN AND MULTIDRUG-RESISTANT ORGANISMS COLONIZATION IN AML PATIENTS.

Author

Guarnera, Luca, primary, Trotta, Gentiana Elena, additional, Boldrini, Valentina, additional, Cardillo, Lucia, additional, Cerroni, Ilaria, additional, Mezzanotte, Valeria, additional, Pasqualone, Gianmario, additional, Savi, Arianna, additional, Borsellino, Beatrice, additional, Buzzatti, Elisa, additional, Palmieri, Raffaele, additional, Paterno, Giovangiacinto, additional, Maurillo, Luca, additional, Buccisano, Francesco, additional, Venditti, Adriano, additional, and Del Principe, Maria Ilaria, additional

Published
2023
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36. Predictors of Early Thrombotic Events in Adult Patients with Acute Myeloid Leukemia: A Real-World Experience

Author

Paterno, Giovangiacinto, primary, Palmieri, Raffaele, additional, Forte, Vittorio, additional, Del Prete, Valentina, additional, Gurnari, Carmelo, additional, Guarnera, Luca, additional, Mallegni, Flavia, additional, Pascale, Maria Rosaria, additional, Buzzatti, Elisa, additional, Mezzanotte, Valeria, additional, Cerroni, Ilaria, additional, Savi, Arianna, additional, Buccisano, Francesco, additional, Maurillo, Luca, additional, Venditti, Adriano, additional, and Del Principe, Maria Ilaria, additional

Published
2022
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37. Risk Factors for Thrombosis in Patients Aged > 60 Years with Essential Thrombocythemia without Previous Thrombotic Events

Author

Latagliata, Roberto, primary, Andriani, Alessandro, additional, Breccia, Massimo, additional, Carmosino, Ida, additional, Vozella, Federico, additional, Romano, Atelda, additional, Biagi, Annalisa, additional, Maurillo, Luca, additional, Trawinska, Malgorzata Monika, additional, Paciaroni, Katia, additional, Santopietro, Michelina, additional, Leonetti Crescenzi, Sabrina, additional, D'Addosio, Ada, additional, Tatarelli, Caterina, additional, Abruzzese, Elisabetta, additional, Di Veroli, Ambra, additional, Rossi, Elena, additional, De Stefano, Valerio, additional, and Montanaro, Marco, additional

Published
2022
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38. Real Life Feasibility of a Combined Clinical and Biological Fitness Assessment in Patients with Acute Myeloid Leukemia

Author

Palmieri, Raffaele, primary, Iacobelli, Simona, additional, Paterno, Giovangiacinto, additional, Federico, Moretti, additional, Buzzatti, Elisa, additional, Elisa, Meddi, additional, Arianna, Savi, additional, Trotta, Gentiana, additional, Mallegni, Flavia, additional, Del Principe, Maria Ilaria, additional, Maurillo, Luca, additional, Voso, Maria Teresa, additional, Venditti, Adriano, additional, and Buccisano, Francesco, additional

Published
2022
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39. The Added Value of Multi-State Modelling in Acute Myeloid Leukemia: The Gimema AML1310 Study Post-Hoc Analysis

Author

Piciocchi, Alfonso, primary, Arena, Valentina, additional, Messina, Monica, additional, Orlando, Sonia Maria, additional, Palmieri, Raffaele, additional, Maurillo, Luca, additional, Del Principe, Maria Ilaria, additional, Fazi, Paola, additional, Vignetti, Marco, additional, Buccisano, Francesco, additional, and Venditti, Adriano, additional

Published
2022
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40. Clinical Characteristics at Onset and Treatment Approaches in Young and Elderly Patients with Essential Thrombocitemia (ET) in Lazio Region: Evaluation of Retrospective and Prospective Databases

Author

Andriani, Alessandro, primary, Breccia, Massimo, additional, Scalzulli, Emilia, additional, Cerchiara, Elisabetta, additional, Romano, Atelda, additional, Biagi, Annalisa, additional, Maurillo, Luca, additional, Trawinska, Malgorzata Monika, additional, Paciaroni, Katia, additional, Santopietro, Michelina, additional, Leonetti Crescenzi, Sabrina, additional, D'Addosio, Ada, additional, Tatarelli, Caterina, additional, Abruzzese, Elisabetta, additional, Di Veroli, Ambra, additional, Rossi, Elena, additional, Latagliata, Roberto, additional, and Montanaro, Marco, additional

Published
2022
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41. Direct CD32 T-cell cytotoxicity: implications for breast cancer prognosis and treatment

Author

Sconocchia, Giuseppe, primary, Lanzilli, Giulia, additional, Cesarini, Valeriana, additional, Silvestris, Domenico A, additional, Rezvani, Katayoun, additional, Arriga, Roberto, additional, Caratelli, Sara, additional, Chen, Ken, additional, Dou, Jinzhuang, additional, Cenciarelli, Carlo, additional, Toietta, Gabriele, additional, Baldari, Silvia, additional, Sconocchia, Tommaso, additional, De Paolis, Francesca, additional, Aureli, Anna, additional, Iezzi, Giandomenica, additional, Irno Consalvo, Maria, additional, Buccisano, Francesco, additional, del Principe, Maria I, additional, Maurillo, Luca, additional, Venditti, Adriano, additional, Ottaviani, Alessio, additional, and Spagnoli, Giulio C, additional

Published
2022
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42. Identification of Predictive Factors for Overall Survival and Response during Hypomethylating Treatment in Very Elderly (≥75 Years) Acute Myeloid Leukemia Patients: A Multicenter Real-Life Experience

Author

Molica, Matteo, primary, Mazzone, Carla, additional, Niscola, Pasquale, additional, Carmosino, Ida, additional, Di Veroli, Ambra, additional, De Gregoris, Cinzia, additional, Bonanni, Fabrizio, additional, Perrone, Salvatore, additional, Cenfra, Natalia, additional, Fianchi, Luana, additional, Piccioni, Anna Lina, additional, Spadea, Antonio, additional, Luzi, Giovanni, additional, Mengarelli, Andrea, additional, Cudillo, Laura, additional, Maurillo, Luca, additional, Pagano, Livio, additional, Breccia, Massimo, additional, Rigacci, Luigi, additional, and De Fabritiis, Paolo, additional

Published
2022
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43. Case report: A Saprochaete clavata (Magnusiomyces clavatus) severe infection effectively treated with granulocyte transfusion in a young patient with myeloid sarcoma

Author

Pasqualone, Gianmario, primary, Buzzatti, Elisa, additional, Palmieri, Raffaele, additional, Savi, Arianna, additional, Pascale, Maria Rosaria, additional, Borsellino, Beatrice, additional, Guarnera, Luca, additional, Buccisano, Francesco, additional, Voso, Maria Teresa, additional, Maurillo, Luca, additional, Sconocchia, Giuseppe, additional, Venditti, Adriano, additional, and Del Principe, Maria Ilaria, additional

Published
2022
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44. Real-life use of erythropoiesis-stimulating agents in myelodysplastic syndromes: a “Gruppo Romano Mielodisplasie (GROM)” multicenter study

Author

Buccisano, Francesco, Piccioni, Anna Lina, Nobile, Carolina, Criscuolo, Marianna, Niscola, Pasquale, Tatarelli, Caterina, Fianchi, Luana, Villivà, Nicoletta, Neri, Benedetta, Carmosino, Ida, Gumenyuk, Svitlana, Mancini, Stefano, Voso, Maria Teresa, Maurillo, Luca, Breccia, Massimo, Zini, Gina, Venditti, Adriano, Fenu, Susanna, Spiriti, Maria Antonietta Aloe, Latagliata, Roberto, and on behalf of GROM (Gruppo Romano Mielodisplasie)

Published
2016
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45. Comparison between azacitidine and decitabine as front-line therapy in elderly treatment naïve Acute Myeloid Leukemia not eligible for intensive chemotherapy

Author

Maurillo, Luca, primary, Spagnoli, Alessandra, additional, Candoni, Anna, additional, Papayannidis, Cristina, additional, Borlenghi, Erika, additional, Lazzarotto, Davide, additional, Fianchi, Luana, additional, Sciumè, Maria Rita, additional, Zannier, Maria Elena, additional, Buccisano, Francesco, additional, Principe, Maria Ilaria Del, additional, Mancini, Valentina, additional, Breccia, Massimo, additional, Fanin, Renato, additional, Todisco, Elisabetta, additional, Lunghi, Monia, additional, Palmieri, Raffaele, additional, Fracchiolla, Nicola, additional, Musto, Pellegrino, additional, Rossi, Giuseppe, additional, and Venditti, Adriano, additional

Published
2022
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47. Erratum:Technical Aspects of Flow Cytometry-based Measurable Residual Disease Quantification in Acute Myeloid Leukemia: Experience of the European LeukemiaNet MRD Working Party (HemaSphere (2022) 6:1 (e676) DOI: 10.1097/HS9.0000000000000676)

Author

Tettero, Jesse M., Freeman, Sylvie D., Buecklein, Veit, Venditti, Adriano, Maurillo, Luca, Kern, Wolfgang, Walter, Roland B., Wood, Brent L., Roumier, Christophe, Philippe, Jan, Denys, Barbara, Jorgensen, Jeffrey L., Bene, Marie C., Lacombe, Francis, Plesa, Adriana, Guzman, Monica L., Wierzbowska, Agnieszka, Czyz, Anna, Ngai, Lok Lam, Schwarzer, Adrian, Bachas, Costa, Cloos, Jacqueline, Subklewe, Marion, Fuering-Buske, Michaela, Buccisano, Francesco, VU University medical center, Hematology laboratory, AII - Cancer immunology, and CCA - Imaging and biomarkers

Abstract

Since the publication of the article entitled Technical Aspects of Flow Cytometry-based Measurable Residual Disease Quantification in Acute Myeloid Leukemia: Experience of the European LeukemiaNet MRD Working Party (HemaSphere. 2022;6(1):e676), the authors have requested a referencing correction. For Table 1, the correct references are 12-16. This has now been adjusted.

Published
2022

48. Identification of Predictive Factors for Overall Survival and Response during Hypomethylating Treatment in Very Elderly (≥75 Years) Acute Myeloid Leukemia Patients: A Multicenter Real-Life Experience

Author

Molica, Matteo, Mazzone, Carla, Niscola, Pasquale, Carmosino, Ida, Di Veroli, Ambra, De Gregoris, Cinzia, Bonanni, Fabrizio, Perrone, Salvatore, Cenfra, Natalia, Fianchi, Luana, Piccioni, Anna Lina, Spadea, Antonio, Luzi, Giovanni, Mengarelli, Andrea, Cudillo, Laura, Maurillo, Luca, Pagano, Livio, Breccia, Massimo, Rigacci, Luigi, De Fabritiis, Paolo, Pagano, Livio (ORCID:0000-0001-8287-928X), Molica, Matteo, Mazzone, Carla, Niscola, Pasquale, Carmosino, Ida, Di Veroli, Ambra, De Gregoris, Cinzia, Bonanni, Fabrizio, Perrone, Salvatore, Cenfra, Natalia, Fianchi, Luana, Piccioni, Anna Lina, Spadea, Antonio, Luzi, Giovanni, Mengarelli, Andrea, Cudillo, Laura, Maurillo, Luca, Pagano, Livio, Breccia, Massimo, Rigacci, Luigi, De Fabritiis, Paolo, and Pagano, Livio (ORCID:0000-0001-8287-928X)

Abstract

Simple Summary Intensive induction strategies are rarely used for older patients in community on-cology practice, with comorbidities being the major cause of contraindication. We conducted a multicentric retrospective study to evaluate activity and safety in a real-life setting of hypomethylating drugs (HMAs) in patients older than 75 years with AML. In multivariate analysis, age (>= 80), Charlson comorbidity index (>= 3), creatinine clearance and the type of best response (>= PR) during treatment maintained independent significance in predicting survival. Furthermore, our data show that HMAs have similar efficacy compared to pivotal trials and are well tolerated in a setting of very elderly patients with several co-comorbidities. Elderly patients represent the most challenging and hard-to-treat patient population due to dismal characteristics of the disease, such as secondary-acute myeloid leukemia (AML), enrichment of unfavorable molecular genes (TP53) and comorbidities. We conducted a multicentric retrospective study to evaluate activity and safety in a real-life setting of hypomethylating drugs (HMAs) in patients older than 75 years with AML. Between September 2010 and December 2021, 220 patients were treated, 164 (74.5%) received AZAcitidine and 56 DECitabine; most patients (57.8%), received more than four cycles of HMAs. The best response obtained was CR in 51 patients (23.2%), PR in 23 (10.5%) and SD in 45 (20.5%); overall transfusion independence was obtained in 47 patients (34%), after a median of 3.5 months. The median OS (mOs) was 8 months (95% CI 5.9-10.2), with 1- and 2-years OS of 39.4% (95% CI 32.7-46) and 17.4% (95% CI 11.7-23.1), respectively; similar mOS was observed according to HMA treatment (AZA 8.3 vs. DEC 7.8 months, p = 0.810). A subset of 57 long survivors (44 in AZA group and 13 in DEC group) received at least 12 cycles of HMAs, their mOS was 24.3 months. In multivariate analysis, age (>= 80), Charlson comorbidity index (>= 3

Published
2022

49. ITACA: A new validated international erythropoietic stimulating agent‐response score that further refines the predictive power of previous scoring systems

Author

Buckstein, Rena, Balleari, Enrico, Wells, Richard, Santini, Valeria, Sanna, Alessandro, Salvetti, Chiara, Crisà, Elena, Allione, Bernardino, Danise, Paolo, Finelli, Carlo, Clavio, Marino, Poloni, Antonella, Salvi, Flavia, Cilloni, Daniela, Oliva, Esther Natalie, Musto, Pellegrino, Houston, Brett, Zhu, Nancy, Geddes, Michelle, Leitch, Heather, Leber, Brian, Sabloff, Mitchell, Nevill, Thomas J., Yee, Karen W., Storring, John M., Francis, Janika, Maurillo, Luca, Latagliata, Roberto, Spiriti, Maria Antonietta Aloe, Andriani, Alessandro, Piccioni, Anna Lina, Fianchi, Luana, Fenu, Susanna, Gumenyuk, Svitlana, and Buccisano, Francesco

Published
2017
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