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Your search keyword '"Masfarre L"' showing total 14 results
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14 results on '"Masfarre L"'

1. P3.13C.06 Artificial Intelligence Meets SCLC - Integrating Clinicopathological and Whole-Slide Image Data for Prognostic Prediction in SCLC.

Author

Rocha, P., Gibert, J., Menendez, S., del Rey-Vergara, R., Iñañez, A., Masfarre, L., Navarro, N., Rios-Hoyo, A., Perez, S., Taus, Á., Giner, M., Rovira, A., León-Mateos, L., Isla, D., Paz-Ares, L., Zugazagoitia, J., Martí Blanco, C., García-Campelo, R., Moreno-Vega, A., Callejo, A., Rojo, F., Sanchez, I., and Arriola, E.

Published
2024
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3. P2.11A.08 Molecular and Immunological Features Associated with Long-Term Benefit in Metastatic NSCLC Patients Undergoing Immune Checkpoint Blockade

Author

Rocha, P., Bach, R., Masfarre, L., Hernandez, S., Navarro-Gorro, N., Rossell, A., Villanueva, X., Giner, M., Sanchez, I., Galindo, M., del Rey-Vergara, R., Iñañez, A., Sanchéz-Espiridion, B., Lu, W., Acedo-Terrades, A., Berenguer-Molins, P., Sánchez-Font, A., Chalela, R., Curull, V., Taus, Á., Hardy-Werbin, M., Sausen, M., Georgiadis, A., White, J., Jackson, J.B., Moliner, L., Clavé, S., Bellosillo, B., Rovira, A., Wistuba, I., Solis Soto, L.M., Perera-Bel, J., and Arriola, E.

Published
2024
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4. Post-exposure prophylaxis for HIV infection in sexual assault victims

Author

Inciarte A, Leal L, Masfarre L, Gonzalez E, Vicens Diaz de Brito Fernandez, Lucero C, Garcia-Pindado J, León A, and García F

Subjects
HIV infections, female, post-exposure prophylaxis, sexual assault, follow-up studies, patient compliance
Abstract

OBJECTIVES: Sexual assault (SA) is recognized as a public health problem of epidemic proportions. Guidelines recommend the administration of post-exposure prophylaxis (PEP) after an SA. However, few data are available about the feasibility of this strategy, and this study was conducted to assess this. METHODS: We conducted a retrospective, longitudinal, observational study in SA victims attending the Hospital Clinic in Barcelona from 2006 to 2015. A total of 1695 SA victims attended the emergency room (ER), of whom 883 met the PEP criteria. Five follow-up visits were scheduled at days 1, 10, 28, 90 and 180 in the out-patient clinic. The primary endpoint was PEP completion rate at day 28. Secondary endpoints were loss to follow-up, treatment discontinuation, occurrence of adverse events (AEs) and rate of seroconversion. RESULTS: The median age of participants was 25 years [interquartile range (IQR) 21-33 years] and 93% were female. The median interval between exposure and presentation at the ER was 13 h (IQR 6-24 h). The level of risk was appreciable in 47% (n = 466) of individuals. Of 883 patients receiving PEP, 631 lived in Catalonia. In this group, the PEP completion rate at day 28 was 29% (n = 183). The follow-up rate was 63% (n = 400) and 38% (n = 241) at days 1 and 28, respectively. Treatment discontinuation was present in 58 (15%) of 400 patients who attended at least the day 1 visit, the main reason being AEs (n = 35; 60%). AEs were reported in 226 (56%) patients, and were mainly gastrointestinal (n = 196; 49%). Only 211 (33%) patients returned for HIV testing at day 90. A single seroconversion was observed in a men who have sex with men (MSM) patient at day 120. CONCLUSIONS: Follow-up and compliance rates in SA victims were poor. In addition, > 50% of the patients experienced AEs, which were the main reason for PEP interruption. Strategies to increase follow-up testing and new better tolerated drug regimens must be investigated to address these issues.

Published
2020

11. 1726P Expanding the role of medical oncologist in the management of COVID-19

Author

Ghiglione, L., Auclin, E., Aguilar-Company, J., Epaillard, N., Casadevall Aguilar, D., Masfarré, L., Rodriguez Castells, M., Tagliamento, M., Pilotto, S., Lopez Castro, R., Mielgo Rubio, X., Urbano Centella, C., Laguna, J.C., García-Illescas, D., Bluthgen, M.V., Gorría Puga, T., Minatta, J.N., Cruz, C.A., Prat, A., and Mezquita, L.

Published
2020
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12. 1714P Change of circulating pro-inflammatory markers between pre-COVID-19 condition and COVID-19 diagnosis predicts early death in cancer patients: The FLARE score

Author

Seguí, E., Auclin, E., Casadevall, D., Aguilar-Company, J., Rodriguez, M., Epaillard, N., Tagliamento, M., Pilotto, S., López-Castro, R., Mielgo, X., Urbano, C., Rodríguez, A., García-Illescas, D., Bluthgen, M.V., Masfarré, L., Oliveres, H., Minatta, J.N., Marco-Hernández, J., Prat, A., and Mezquita, L.

Published
2020
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14. Palinopsia associated with the CDK4/6 inhibitor ribociclib during the first-line treatment of metastatic breast cancer: two case reports.

Author

Martos T, Saint-Gerons M, Masfarre L, Castro-Henriques M, Martinez-Garcia M, Servitja S, and Albanell J

Abstract

The most frequently used standard treatment for hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer patients consists of a CDK4/6 inhibitor (abemaciclib, ribociclib, or palbociclib) combined with endocrine therapy. Despite CDK4/6 inhibitors being part of routine care in the last few years, new adverse events continue to be reported. Here, we report two cases of palinopsia, a rare neurological visual disturbance that refers to the persistence or recurrence of a visual image after the removal of visual stimuli in patients treated with ribociclib and letrozole. Neuro-ophthalmological assessments and brain MRIs did not find any organic cause. However, palinopsia was related in a time- and dose-dependent manner to the intake of ribociclib. Following a one-level dose reduction of ribociclib, palinopsia was mild and well tolerated. Both patients continued the treatment with ribociclib, with one of them for almost 2 years. Based on the identification of two cases in our hospital in a short period of time, it is tempting to suggest that ribociclib-related palinopsias may not be uncommon. We propose that physicians should be aware of this ribociclib-associated adverse event. Patients presenting this symptom should undergo a routine workup (neuro-ophthalmological assessment and brain MRI) and, if negative, be reassured of its relation with ribociclib as well as the safety of continuing on this drug., Competing Interests: The authors declare that the research was conducted in absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Martos, Saint-Gerons, Masfarre, Castro-Henriques, Martinez-Garcia, Servitja and Albanell.)

Published
2024
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