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34 results on '"Marotti, Lorenza"'

1. Management of the axilla in breast cancer patients: critical review, regional modified Delphi consensus and implementation in the Tuscan breast network

Author

Ghilli, Matteo, Becherini, Carlotta, Meattini, Icro, Angiolini, Catia, Bengala, Carmelo, Marconi, Aroldo, Galli, Lorenzo, Angiolucci, Giovanni, Coltelli, Luigi, Borghesi, Simona, Lastrucci, Luciana, Manca, Gianpiero, Bianchi, Simonetta, Doria, Morena, Casella, Donato, Marotti, Lorenza, Amunni, Gianni, and Roncella, Manuela

Published
2024
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2. EUSOMA quality indicators for non-metastatic breast cancer: An update

Author

Rubio, Isabel T., Marotti, Lorenza, Biganzoli, Laura, Aristei, Cynthia, Athanasiou, Alexandra, Campbell, Christine, Cardoso, Fatima, Cardoso, Maria Joao, Coles, Charlotte E., Eicher, Manuela, Harbeck, Nadia, Karakatsanis, Andreas, Offersen, Birgitte V., Pijnappel, Ruud, Ponti, Antonio, Regitnig, Peter, Santini, Donatella, Sardanelli, Francesco, Spanic, Tanja, Varga, Zsuzsanna, Vrancken Peeters, Marie Jeanne T.F.D., Wengström, Yvonne, Wyld, Lynda, and Curigliano, Giuseppe

Published
2024
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3. European guidelines for the diagnosis, treatment and follow-up of breast lesions with uncertain malignant potential (B3 lesions) developed jointly by EUSOMA, EUSOBI, ESP (BWG) and ESSO

Author

Rubio, Isabel T., Wyld, Lynda, Marotti, Lorenza, Athanasiou, Alexandra, Regitnig, Peter, Catanuto, Giuseppe, Schoones, Jan W., Zambon, Marzia, Camps, Julia, Santini, Donatella, Dietz, Jill, Sardanelli, Francesco, Varga, Zsuzsanna, Smidt, Marjolein, Sharma, Nisha, Shaaban, Abeer M., and Gilbert, Fiona

Published
2024
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4. Treatment and outcomes in breast cancer patients: A cross section study from the EUSOMA breast centre network

Author

Baldissera, Antonella, Benozzi, Elisabetta, Berger, Johannes, Bortul, Marina, Bussels, Barbara, Cagossi, Katia, Caruso, Francesco, Cedolini, Carla, Corsi, Fabio, Despierre, Evelyn, Despini, Luca, Duhoux, Francois P, Esgueva, Antonio J., Ferrari, Alberta, Fogazzi, Gianluca, Fortunato, Lucio, Fougo, José Luis, Generali, Daniele, Gennari, Alessandra, Ghilli, Matteo, Gianni, Lorenzo, Grossi, Simona, Huscher, Alessandra, Kozłowski, Leszek, Larsson, Karolina, Matos, Leonor, Montemezzi, Stefania, Musolino, Antonio, Negreiros, Ida, Orye, Guy, Polato, Romano, Prové, Annemie, Romanucci, Giovanna, Rossi, Lorenzo, Staelens, Gracienne, Tazzioli, Giovanni, Trunfio, Martino, Vassilieff, Maud, Verhoeven, Didier, Veronesi, Paolo, Zamagni, Claudio, Aristei, Cynthia, Tomatis, Mariano, Antonio Ponti, Marotti, Lorenza, Cardoso, Maria Joao, Cheung, Kwok Leung, Curigliano, Giuseppe, De Vries, Jakob, Santini, Donatella, Sardanelli, Francesco, Van Dam, Peter, and Rubio, Isabel Teresa

Published
2024
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8. The impact of the SARS-COV-2 pandemic on the quality of breast cancer care in EUSOMA-certified breast centres

Author

Baldini, Valentina, Ballardini, Bettina, Berger, Johannes, Berlière, Martine, Bonetti, Andrea, Bortul, Marina, Bussels, Barbara, Cagossi, Katia, Epifanio Castiglione, Gaetano Antonio, Cedolini, Carla, Esgueva Colmenarejo, Antonio J., Corsi, Fabio, Cretella, Elisabetta, Fogazzi, Gianluca, Fortunato, Lucio, Fougo, José Luis, Generali, Daniele, Gouveia, Pedro F., Grossi, Simona, Huscher, Alessandra, Kaelides, Michalis, Kuhn, Elisabetta, Levy, Christelle, Massarut, Samuele, Meani, Francesco, Montemezzi, Stefania, Musolino, Antonio, Negreiros, Ida, Bagge, Roger Olofsson, Pagani, Gianmatteo, Peterko, Ana Car, Prové, Annemie, Roelstraete, Heidi, Roncella, Manuella, Saguatti, Gianni, Sarlos, Dimitri, Sgarella, Adele, Staelens, Gracienne, Taffurelli, Mario, Tazzioli, Giovanni, Tinterri, Corrado, Vassilieff, Maud, Verhoeven, Didier, van Dam, Peter, Tomatis, Mariano, Ponti, Antonio, Marotti, Lorenza, Aristei, Cynthia, Biganzoli, Laura, Cardoso, Maria J, Cheung, Kwok L, Curigliano, Giuseppe, De Vries, Jakob, Santini, Donatella, Sardanelli, Francesco, and Rubio, Isabel Teresa

Published
2022
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9. Updated recommendations regarding the management of older patients with breast cancer: a joint paper from the European Society of Breast Cancer Specialists (EUSOMA) and the International Society of Geriatric Oncology (SIOG)

Author

Biganzoli, Laura, Battisti, Nicolò Matteo Luca, Wildiers, Hans, McCartney, Amelia, Colloca, Giuseppe, Kunkler, Ian H, Cardoso, Maria-João, Cheung, Kwok-Leung, de Glas, Nienke Aafke, Trimboli, Rubina M, Korc-Grodzicki, Beatriz, Soto-Perez-de-Celis, Enrique, Ponti, Antonio, Tsang, Janice, Marotti, Lorenza, Benn, Karen, Aapro, Matti S, and Brain, Etienne G C

Published
2021
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10. EUSOMA quality indicators for non-metastatic breast cancer: An update

Author

MS Radiologie, Cancer, Rubio, Isabel T, Marotti, Lorenza, Biganzoli, Laura, Aristei, Cynthia, Athanasiou, Alexandra, Campbell, Christine, Cardoso, Fatima, Cardoso, Maria Joao, Coles, Charlotte E, Eicher, Manuela, Harbeck, Nadia, Karakatsanis, Andreas, Offersen, Birgitte V, Pijnappel, Ruud, Ponti, Antonio, Regitnig, Peter, Santini, Donatella, Sardanelli, Francesco, Spanic, Tanja, Varga, Zsuzsanna, Vrancken Peeters, Marie Jeanne T F D, Wengström, Yvonne, Wyld, Lynda, Curigliano, Giuseppe, MS Radiologie, Cancer, Rubio, Isabel T, Marotti, Lorenza, Biganzoli, Laura, Aristei, Cynthia, Athanasiou, Alexandra, Campbell, Christine, Cardoso, Fatima, Cardoso, Maria Joao, Coles, Charlotte E, Eicher, Manuela, Harbeck, Nadia, Karakatsanis, Andreas, Offersen, Birgitte V, Pijnappel, Ruud, Ponti, Antonio, Regitnig, Peter, Santini, Donatella, Sardanelli, Francesco, Spanic, Tanja, Varga, Zsuzsanna, Vrancken Peeters, Marie Jeanne T F D, Wengström, Yvonne, Wyld, Lynda, and Curigliano, Giuseppe

Published
2024

11. European guidelines for the diagnosis, treatment and follow-up of breast lesions with uncertain malignant potential (B3 lesions) developed jointly by EUSOMA, EUSOBI, ESP (BWG) and ESSO

Author

Rubio, Isabel T; https://orcid.org/0000-0003-0035-0679, Wyld, Lynda, Marotti, Lorenza, Athanasiou, Alexandra, Regitnig, Peter; https://orcid.org/0000-0002-1371-1595, Catanuto, Giuseppe, Schoones Ma, Jan W, Zambon, Marzia, Camps, Julia, Santini, Donatella, Dietz, Jill, Sardanelli, Francesco; https://orcid.org/0000-0001-6545-9427, Varga, Zsuzsanna; https://orcid.org/0000-0002-2855-983X, Smidt, Marjolein, Sharma, Nisha; https://orcid.org/0000-0003-3991-0768, Shaaban, Abeer M, Gilbert, Fiona, Rubio, Isabel T; https://orcid.org/0000-0003-0035-0679, Wyld, Lynda, Marotti, Lorenza, Athanasiou, Alexandra, Regitnig, Peter; https://orcid.org/0000-0002-1371-1595, Catanuto, Giuseppe, Schoones Ma, Jan W, Zambon, Marzia, Camps, Julia, Santini, Donatella, Dietz, Jill, Sardanelli, Francesco; https://orcid.org/0000-0001-6545-9427, Varga, Zsuzsanna; https://orcid.org/0000-0002-2855-983X, Smidt, Marjolein, Sharma, Nisha; https://orcid.org/0000-0003-3991-0768, Shaaban, Abeer M, and Gilbert, Fiona

Abstract

Introduction: Breast lesions of uncertain malignant potential (B3) include atypical ductal and lobular hyperplasias, lobular carcinoma in situ, flat epithelial atypia, papillary lesions, radial scars and fibroepithelial lesions as well as other rare miscellaneous lesions. They are challenging to categorise histologically, requiring specialist training and multidisciplinary input. They may coexist with in situ or invasive breast cancer (BC) and increase the risk of subsequent BC development. Management should focus on adequate classification and management whilst avoiding overtreatment. The aim of these guidelines is to provide updated information regarding the diagnosis and management of B3 lesions, according to updated literature review evidence. Methods: These guidelines provide practical recommendations which can be applied in clinical practice which include recommendation grade and level of evidence. All sections were written according to an updated literature review and discussed at a consensus meeting. Critical appraisal by the expert writing committee adhered to the 23 items in the international Appraisal of Guidelines, Research and Evaluation (AGREE) tool. Results: Recommendations for further management after core-needle biopsy (CNB) or vacuum-assisted biopsy (VAB) diagnosis of a B3 lesion reported in this guideline, vary depending on the presence of atypia, size of lesion, sampling size, and patient preferences. After CNB or VAB, the option of vacuum-assisted excision or surgical excision should be evaluated by a multidisciplinary team and shared decision-making with the patient is crucial for personalizing further treatment. De-escalation of surgical intervention for B3 breast lesions is ongoing, and the inclusion of vacuum-assisted excision (VAE) will decrease the need for surgical intervention in further approaches. Communication with patients may be different according to histological diagnosis, presence or absence of atypia, or risk of upgrade due to d

Published
2024

12. The requirements of a specialist breast centre

Author

Biganzoli, Laura, Cardoso, Fatima, Beishon, Marc, Cameron, David, Cataliotti, Luigi, Coles, Charlotte E., Delgado Bolton, Roberto C., Trill, Maria Die, Erdem, Sema, Fjell, Maria, Geiss, Romain, Goossens, Mathijs, Kuhl, Christiane, Marotti, Lorenza, Naredi, Peter, Oberst, Simon, Palussière, Jean, Ponti, Antonio, Rosselli Del Turco, Marco, Rubio, Isabel T., Sapino, Anna, Senkus-Konefka, Elzbieta, Skelin, Marko, Sousa, Berta, Saarto, Tiina, Costa, Alberto, and Poortmans, Philip

Published
2020
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13. Corrigendum to “European guidelines for the diagnosis, treatment and follow-up of breast lesions with uncertain malignant potential (B3 lesions) developed jointly by EUSOMA, EUSOBI, ESP (BWG) and ESSO” [Eur J Surg Oncol 50 (1) (January 2024) 107292]

Author

Rubio, Isabel T., primary, Wyld, Lynda, additional, Marotti, Lorenza, additional, Athanasiou, Alexandra, additional, Regitnig, Peter, additional, Catanuto, Giuseppe, additional, Schoones, Jan W., additional, Zambon, Marzia, additional, Camps, Julia, additional, Santini, Donatella, additional, Dietz, Jill, additional, Sardanelli, Francesco, additional, Varga, Zsuzsanna, additional, Smidt, Marjolein, additional, Sharma, Nisha, additional, Shaaban, Abeer M., additional, and Gilbert, Fiona, additional

Published
2024
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14. EUSOMA quality indicators for non-metastatic breast cancer: An update

Author

Rubio, Isabel T., primary, Marotti, Lorenza, additional, Biganzoli, Laura, additional, Aristei, Cynthia, additional, Athanasiou, Alexandra, additional, Campbell, Christine, additional, Cardoso, Fatima, additional, Cardoso, Maria Joao, additional, Coles, Charlotte E., additional, Eicher, Manuela, additional, Harbeck, Nadia, additional, Karakatsanis, Andreas, additional, Offersen, Birgitte V., additional, Pijnappel, Ruud, additional, Ponti, Antonio, additional, Regitnig, Peter, additional, Santini, Donatella, additional, Sardanelli, Francesco, additional, Spanic, Tanja, additional, Varga, Zsuzsanna, additional, Vrancken Peeters, Marie Jeanne T.F.D., additional, Wengström, Yvonne, additional, Wyld, Lynda, additional, and Curigliano, Giuseppe, additional

Published
2023
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15. Trends in axillary lymph node dissection for early-stage breast cancer in Europe: Impact of evidence on practice

Author

Danaei, Mahmoud, Stickeler, Elmar, Sarlos, Dimitri, Prové, Annemie, Pagani, Olivia, Berclaz, Gilles, Taffurelli, Mario, Cretella, Elisabetta, Verhoeven, Didier, Denk, Andreas, Carly, Birgit, Ballardini, Bettina, van Riet, Yvonne, Kimmig, Rainer, Reinisch, Mattea, Angiolini, Catia, Möbus, Volker, Emons, Gunter, Friedrichs, Kay, Schneeweiss, Andreas, Tinterri, Corrado, Egle, Daniel, Staelens, Gracienne, Kiechle, Marion, Harbeck, Nadia, Corsi, Fabio, Menghini, Lorenzo, Lombardi, Augusto, Fortunato, Lucio, Bortul, Marina, Huober, Jens, Badbanchi, Farzaneh, Tausch, Christoph, Garcia-Etienne, Carlos A., Mansel, Robert E., Tomatis, Mariano, Heil, Joerg, Biganzoli, Laura, Ferrari, Alberta, Marotti, Lorenza, Sgarella, Adele, and Ponti, Antonio

Published
2019
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16. Treatment and outcomes in breast cancer patients: a cross section study from the EUSOMA Breast Centre Network

Author

Aristei, Cynthia, primary, Tomatis, Mariano, additional, Ponti, Antonio, additional, Marotti, Lorenza, additional, Cardoso, Maria Joao, additional, Cheung, Kwok Leung, additional, Curigliano, Giuseppe, additional, De Vries, Jakob, additional, Santini, Donatella, additional, Sardanelli, Francesco, additional, Van Dam, Peter, additional, and Rubio, Isabel Teresa, additional

Published
2023
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17. European guidelines for the diagnosis, treatment and follow-up of breast lesions with uncertain malignant potential (B3 lesions) developed jointly by EUSOMA, EUSOBI, ESP (BWG) and ESSO

Author

Rubio, Isabel T., primary, Wyld, Lynda, additional, Marotti, Lorenza, additional, Athanasiou, Alexandra, additional, Regitnig, Peter, additional, Catanuto, Giuseppe, additional, Schoones Ma, Jan W., additional, Zambon, Marzia, additional, Camps, Julia, additional, Santini, Donatella, additional, Dietz, Jill, additional, Sardanelli, Francesco, additional, Varga, Zsuzsanna, additional, Smidt, Marjolein, additional, Sharma, Nisha, additional, Shaaban, Abeer M., additional, and Gilbert, Fiona, additional

Published
2023
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22. EUSOMA

Author

Marotti, Lorenza, additional, Cataliotti, Luigi, additional, and Mansel, Robert, additional

Published
2019
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23. The impact of the SARS-COV-2 pandemic on the quality of breast cancer care in EUSOMA-certified breast centres

Author

van Dam, Peter, primary, Tomatis, Mariano, additional, Ponti, Antonio, additional, Marotti, Lorenza, additional, Aristei, Cynthia, additional, Biganzoli, Laura, additional, Cardoso, Maria J, additional, Cheung, Kwok L, additional, Curigliano, Giuseppe, additional, De Vries, Jakob, additional, Santini, Donatella, additional, Sardanelli, Francesco, additional, Rubio, Isabel Teresa, additional, Baldini, Valentina, additional, Ballardini, Bettina, additional, Berger, Johannes, additional, Berlière, Martine, additional, Bonetti, Andrea, additional, Bortul, Marina, additional, Bussels, Barbara, additional, Cagossi, Katia, additional, Epifanio Castiglione, Gaetano Antonio, additional, Cedolini, Carla, additional, Esgueva Colmenarejo, Antonio J., additional, Corsi, Fabio, additional, Cretella, Elisabetta, additional, Fogazzi, Gianluca, additional, Fortunato, Lucio, additional, Fougo, José Luis, additional, Generali, Daniele, additional, Gouveia, Pedro F., additional, Grossi, Simona, additional, Huscher, Alessandra, additional, Kaelides, Michalis, additional, Kuhn, Elisabetta, additional, Levy, Christelle, additional, Massarut, Samuele, additional, Meani, Francesco, additional, Montemezzi, Stefania, additional, Musolino, Antonio, additional, Negreiros, Ida, additional, Bagge, Roger Olofsson, additional, Pagani, Gianmatteo, additional, Peterko, Ana Car, additional, Prové, Annemie, additional, Roelstraete, Heidi, additional, Roncella, Manuella, additional, Saguatti, Gianni, additional, Sarlos, Dimitri, additional, Sgarella, Adele, additional, Staelens, Gracienne, additional, Taffurelli, Mario, additional, Tazzioli, Giovanni, additional, Tinterri, Corrado, additional, Vassilieff, Maud, additional, and Verhoeven, Didier, additional

Published
2022
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25. Eusoma/Abc Global Alliance Quality Indicators for Metastatic Breast Cancer Care

Author

Cardoso, Fatima, primary, McCartney, Amelia, additional, Ponti, Antonio, additional, Marotti, Lorenza, additional, Vrieling, Conny, additional, Eniu, Alexandru, additional, Sousa, Berta, additional, Ripamonti, Carla, additional, Travado, Luzia, additional, Spitz, Sabine, additional, Gustafsson, Eva, additional, Rubio, Isabel T., additional, and Biganzoli, Laura, additional

Published
2022
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27. Trends in axillary lymph node dissection for early-stage breast cancer in Europe: Impact of evidence on practice

Author

Garcia-Etienne, Carlos A., Mansel, Robert E., Tomatis, Mariano, Heil, Joerg, Biganzoli, Laura, Ferrari, Alberta, Marotti, Lorenza, Sgarella, Adele, Ponti, Antonio, Danaei, Mahmoud, Stickeler, Elmar, Sarlos, Dimitri, Prové, Annemie, Pagani, Olivia, Berclaz, Gilles, Taffurelli, Mario, Cretella, Elisabetta, Verhoeven, Didier, Denk, Andreas, Carly, Birgit, Ballardini, Bettina, van Riet, Yvonne, Kimmig, Rainer, Reinisch, Mattea, Angiolini, Catia, Möbus, Volker, Emons, Gunter, Friedrichs, Kay, Schneeweiss, Andreas, Tinterri, Corrado, Egle, Daniel, Staelens, Gracienne, Kiechle, Marion, Harbeck, Nadia, Corsi, Fabio, Menghini, Lorenzo, Lombardi, Augusto, Fortunato, Lucio, Bortul, Marina, Huober, Jens, Badbanchi, Farzaneh, Tausch, Christoph, EUSOMA Working Group, EUSOMA Working Grp, Garcia-Etienne, C. A., Mansel, R. E., Tomatis, M., Heil, J., Biganzoli, L., Ferrari, A., Marotti, L., Sgarella, A., Ponti, A., Danaei, M., Stickeler, E., Sarlos, D., Prove, A., Pagani, O., Berclaz, G., Taffurelli, M., Cretella, E., Verhoeven, D., Denk, A., Carly, B., Ballardini, B., van Riet, Y., Kimmig, R., Reinisch, M., Angiolini, C., Mobus, V., Emons, G., Friedrichs, K., Schneeweiss, A., Tinterri, C., Egle, D., Staelens, G., Kiechle, M., Harbeck, N., Corsi, F., Menghini, L., Lombardi, A., Fortunato, L., Bortul, M., Huober, J., Badbanchi, F., and Tausch, C.

Subjects
axillary lymph node dissection, axillary dissection, axillary surgery, axillary lymphadenectomy, positive sentinel node, Z0011, surgery for breast cancer, Medizin, Practice Patterns, Axillary dissection, 0302 clinical medicine, Axillary lymph node dissection, Breast, 030212 general & internal medicine, Practice Patterns, Physicians', Stage (cooking), Surgical approach, Lymph Node, Axillary lymphadenectomy, General Medicine, Middle Aged, 3. Good health, Europe, medicine.anatomical_structure, Homogeneous, 030220 oncology & carcinogenesis, Female, Axillary surgery, Positive sentinel node, Surgery for breast cancer, Adult, Aged, Axilla, Breast Neoplasms, Humans, Lymph Node Excision, Lymph Nodes, Breast Neoplasm, Human, medicine.medical_specialty, 03 medical and health sciences, Breast cancer, medicine, Physicians', Breast conservation, business.industry, General surgery, Background data, Axillary Lymph Node Dissection, medicine.disease, Surgery, Human medicine, business
Abstract

Background: Data from recently published trials have provided practice-changing recommendations for the surgical approach to the axilla in breast cancer. Patients with T1-2 lesions, treated with breast conservation, who have not received neoadjuvant chemotherapy and have 1-2 positive sentinel nodes (Z0011-criteria) may avoid axillary lymph node dissection (ALND). We aim to describe the dissemination of this practice in Europe over an extended period of time. Methods: Our source of data was the eusomaDB, a central data warehouse of prospectively collected information of the European Society of Breast Cancer Specialists (EUSOMA). We identified cases fulfilling Z0011-criteria from 2005 to 2016 from 34 European breast centers and report trends in ALND. Data derived from Germany, Italy, Belgium, Switzerland, Austria, and Netherlands. Results: 6671 patients fulfilled Z0011-criteria. Rates of ALND showed a statistically significant decrease from 2010 (89%) to 2011 (73%), reaching 46% in 2016 (p < 0.001). After multivariable analysis, factors associated with higher probability of ALND were earlier year of surgery, younger age, increasing tumor size and grade, and being operated in Italy (p < 0.001). The minimum and maximal rates of ALND in the most recent two-year period (2015-2016) were 0% and 83% in two centers located in different countries (p < 0.001). Conclusion: Our study demonstrates, a decrease in rates of ALND that started after year 2010 through the end of the study period. Wide differences were observed among centers and countries indicating the need to spread unified clinical guidelines in Europe to allow for homogeneous evidence-based practice patterns. (C) 2019 Elsevier Ltd. All rights reserved.

Published
2019

29. European Guidelines on the Organisation of Breast Centres and Voluntary Certification Processes

Author

Biganzoli, Laura, primary, Marotti, Lorenza, additional, Cardoso, Maria-Joao, additional, Cataliotti, Luigi, additional, Curigliano, Giuseppe, additional, Cuzick, Jack, additional, Goldhirsch, Aaron, additional, Leidenius, Marjut, additional, Mansel, Robert, additional, Markopoulos, Christos, additional, Wyld, Lynda, additional, and Rubio, Isabel T., additional

Published
2019
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30. Reply to letter from Suguatti et al.

Author

Cataliotti, Luigi, primary, Marotti, Lorenza, additional, Beishon, Marc, additional, Costa, Alberto, additional, Knox, Susan, additional, Rutgers, Emiel, additional, and Cardoso, Fatima, additional

Published
2017
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31. Data managers: A survey of the European Society of Breast Cancer Specialists in certified multi‐disciplinary breast centers.

Author

the EUSOMA Breast Centers Network Data Managers, Schnapper, Gabriele, Marotti, Lorenza, Ponti, Antonio, Mansel, Robert E., Casella, Denise, and Mano, Maria P.

Subjects
BREAST tumors, CANCER treatment, DATABASE management, PSYCHOLOGY of executives, JOB satisfaction, QUESTIONNAIRES, OCCUPATIONAL roles, SPECIALTY hospitals
Abstract

Abstract: The European Society of Breast Cancer Specialists (EUSOMA) requires that the breast centers' core team includes a trained person responsible for data collection and analysis. We addressed a questionnaire to the data managers of the EUSOMA breast centers network in order to acquire information with regard to their education, training, role, activity, recognition, and satisfaction. Breast centers' data managers are highly educated individuals with a variety of backgrounds carrying out, more frequently part‐time and as temporary employees, a job for which they received little specific training. These findings support the importance of defining a core curriculum and a training program. [ABSTRACT FROM AUTHOR]

Published
2018
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33. Treatment and outcomes in breast cancer patients: A cross section study from the EUSOMA breast centre network.

Author

Aristei, Cynthia, Tomatis, Mariano, Antonio Ponti, Marotti, Lorenza, Cardoso, Maria Joao, Cheung, Kwok Leung, Curigliano, Giuseppe, De Vries, Jakob, Santini, Donatella, Sardanelli, Francesco, Van Dam, Peter, and Rubio, Isabel Teresa

Subjects
*BREAST cancer prognosis, *DNA metabolism, *LYMPHOCYTE metabolism, *SPECIALTY hospitals, *CROSS-sectional method, *MULTIVARIATE analysis, *EPIDERMAL growth factor receptors, *METASTASIS, *CANCER treatment, *TREATMENT effectiveness, *CANCER patients, *RISK assessment, *TUMOR classification, *GENE expression, *QUALITY of life, *DESCRIPTIVE statistics, *DATA analysis, *PROGRESSION-free survival, *COMBINED modality therapy, *TUMOR markers, *CERTIFICATION, *RADIOTHERAPY, *BREAST tumors
Abstract

The present study was designed to describe tumour features and treatments for patients with breast cancer. It also aimed at assessing the risk of distant metastases in relation to biological profiles, disease stages and treatment. Data were analysed from 81,882 patients in the EUSOMA database (disease stages at diagnosis 0-IV; median age 61 years; range 20–100 years). All patients were treated between January 2016 and December 2021 in 53 Breast Centres within the EUSOMA certification process in 13 European countries. Cases were classified as HR+ /HER2-, HR+ /HER2 + , HR-/HER2 + or HR-/HER2- and data were analysed accordingly. Univariable and multivariable analyses for distant metastases were conducted on a subset of 38,119 cases with information on whether or not they had developed them. Potential determinants included sub-group type, Ki67 value, disease stage, adjuvant systemic therapies and post-operative radiation therapy. In multivariable analysis, the HR-/HER2 + and HR-/HER2- sub-groups were associated with a higher risk of distant metastases than HR+ /HER2–. Ki67 > 20 % and advanced stage disease also carried a high risk. Radiation therapy emerged as a protective factor against distant metastases. Present results show a large patient database offers an information stream that can be applied to reduce uncertainties in clinical practice. Database parameters need to be updated dynamically for outcome monitoring. Molecular prognostic factors, gene-expression signatures, tumour-infiltrating lymphocytes and circulating tumoral DNA should be added. • European multi-centre data analysis of breast cancer, describing tumour features and treatments. • HR-/HER2 + and HR-/HER2- sub-types were linked with a high risk of distant metastases. • Ki67 > 20% and advanced stage disease carried a high risk. • Radiation therapy emerged as a protective factor against distant metastases. [ABSTRACT FROM AUTHOR]

Published
2024
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34. Data managers: A survey of the European Society of Breast Cancer Specialists in certified multi-disciplinary breast centers.

Author

Schnapper G, Marotti L, Casella D, Mano MP, Mansel RE, and Ponti A

Subjects
Adult, Breast Neoplasms therapy, Cancer Care Facilities legislation & jurisprudence, Europe, Female, Health Personnel statistics & numerical data, Humans, Male, Middle Aged, Societies, Medical, Specialization, Surveys and Questionnaires, Cancer Care Facilities organization & administration, Certification standards
Abstract

The European Society of Breast Cancer Specialists (EUSOMA) requires that the breast centers' core team includes a trained person responsible for data collection and analysis. We addressed a questionnaire to the data managers of the EUSOMA breast centers network in order to acquire information with regard to their education, training, role, activity, recognition, and satisfaction. Breast centers' data managers are highly educated individuals with a variety of backgrounds carrying out, more frequently part-time and as temporary employees, a job for which they received little specific training. These findings support the importance of defining a core curriculum and a training program., (© 2018 Wiley Periodicals, Inc.)

Published
2018
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